CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Aches and pains None Tried to stop. After two months remembered why I took in in the first place F 68 5 years
20
10/2/2019
 1  anxiety and arthritis Constant nausea from day one. Could not tolerate this medicine. M 65 10 days
20 2X day
9/13/2019
 1  Possible Fyrbomyalgia and Vulvodyni Painful clitoris!! Like I was punched in the funny bone but down there. I can barely walk! Entire body feels tingly and strange. Arms and hands shaking, anxiety, brain fog, mood swings, heart is racing nonstop. It's only day 7 and judging by the way I feel as well as everyone's horrifying comments, I am not taking this ever again. I feel crazy! I seriously can't function. I'll take the condition I have over this. F 37 7 days
20mg
8/16/2019
Email
 1  C-PTSD, depression, anxiety Panic attacks, derealization, depersonalization, bilateral leg weakness, vivid dreams, headache, teeth grinding I had hoped this would work, but the panic attacks were intense and long lasting. First Rx that's done that. Very scary, can't recommend F 54 9 days
30 mg
7/24/2019
 2  Depression and anxiety Sweating, no appetite at first, lost weight. Then, gained a lot of weight. Sleepiness, insomnia, need higher dose and another med to manage insomnia, depression and severe anxiety. Don't take it. F 53 6 days
90
6/21/2019
 4  Chronic Pain Withdrawal symptoms when missed dosage. Unexpected mood enhancement. M 30 2 years
20 MG
6/2/2019
 1  Depression Serotonin syndrome, what I called the "zippy zappies," the arm and brain tingles This took around 6 months after completely stopping (after tapering down) taking this medication. Its beneficial effects were short lived and its side effects lasted the whole time, but the worst thing was stopping taking it, i felt absolutely awful for months, which is not something that a depressive person like me should have to deal with on top of my illness. F 47 2 years
1X day
6/2/2019
 4  Depression Sick constipation M 47 0 days
60
5/24/2019
 1  Depression and anxiety It has added more anxiety and also badly caused severe pain in urinary tract , bad pain in bladder, penis and all muscles whole body. It is very dangerous drug. Side effects are much more than any little benefits . try natural treatments . try omega 3. M 60 1 months
5/15/2019
Email
 5  Depression, grief, severe headaches Always thirsty, dry mouth, some restlessness, jittery at times I have to say that I was not wanting to get back on an anti-depressant after being off them for years, but I'm a bereaved Mom and the sadness is a constant struggle. I also had daily stress headaches and that in itself was making me very depressed. I started taking 30 mg, and a week later up to 60 mg. My appetite is less (not a bad thing), I have not had a headache since beginning Cymbalta. My body aches are lessened. It feels like someone turned the "volume" down in my head so my sadness and depressed mood are almost gone. I'm looking forward to things again, I feel hopeful and happier than I have in awhile. I've read all the awful reviews and I'm happy I have nothing but good to report. It has really pulled me out of a bad space, so I'm able to be a functioning happy Mom and wife again. F 52 3 weeks
60mg 1X day
5/9/2019
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 4  Depressed mood & chronic pain. Some negligible tingling in my extremities just as the pain relief benefits set in. Typical sexual side effects everyone has heard about. Helps mood. I respond to antidepressants the same day I take them, so I have never had to take it on a regular basis, only as needed. M 40 1 years
30 mg 1X day
3/16/2019
 1  Osteoarthritis I felt pain relief within 7 hours of the first dose, but felt so sick and anxious. I got a headache that turned into a 4 day migraine. Stopped meds. Can’t afford to miss work and I’m very sensitive to meds and know if this were to work it would probably take me a couple of weeks to get used to it and just can’t afford to miss work. After reading all the problems people had with it, I don’t think I want to try it again anyway. F 52 1 days
30mg
3/4/2019
Email
 1  Back pain, anxiety, weight loss Anxiety, diarrhea, stomach upset Like hell to get off of, rebound insomnia, never the same again. Took after coming off amitriptyline which stopped working. F 63 3 months
10
3/1/2019
 3  Depression Maybe constipation. I’m not really feeling better. My Dr just Raised me from 40 to 80mg. We will see. Really Scary stories guys. I had very aggressive breast cancer. Now I’m cancer free. Im just having awful depression. F 57 6 days
80mg
2/6/2019
Email
 1  Fibromyalgia Horrible drug. Internal bleeding. Don’t take this drug. Changes you. F 60 5 years
60
2/1/2019
 2  depression first month total constipation, then liquid diarrhea. Transition from venlafaxine (Effexor) to cymbalta, so no other new side effects. Very hard to stop also. Doctors told me cymbalta couldn't cause my symptoms. Hopefully I tried to stop it 3 days before examinations (coloscopy), well cymbalta was the cause. Took 3 months more to go back to normal digestive functions. F 44 3 months
60 mg 1X day
12/28/2018
 1  yes I was stoned, and did not know what I was doing, or where I was even though I was at home. Just glad that I did not do this on a work day, as I probably would have stopped on a green and gone on the red. I was that wasted. I knew that something was wrong and hate not being in control so I refused to take anymore. Why is this considered a good alternative for pain, when I have no problems with any of the opiates? The only thing that I have had happen with things such as morphine is that it made me a little foggy and tired, but I had my whits about me. Same with Norco, that Kaiser wanted to get me off so bad that they lied about me saying that I wanted norco and nothing else. Even though I had asked for something else that is safer because of the acetaminophen in it and more effective long term against pain. Methadone is safer and yet they do not have it and it is harder to get unless you are previously a drug addict. M 53 1 days
20mg 1X day
12/24/2018
 1  Depression Was ok at first after 2years of taking med then started experiencing severe fatigue nausea and more headaches,body aches . Trying to come off the medication is worse than what I went on it for this drug should not be prescribed anymore period causes long term problems . F 54 3 years
30 mg
12/22/2018
 3  Rheumatoid arthritis:dysthymia. Zombie-like state. Slept every second of every day. Best sleeping I ever did! I would look at my two dogs signaling me to go out and think I am too tired, just let me sleep a bit longer and fall back asleep. My body, however, felt normal. It no longer hurt to walk with no shoes or stand barefoot whilst washing dishes. My husband commented, well as long as it is helping with your pain, but you seem like you are walking in your sleep. I quit taking 60 mg a day and called my doc asking for the lowest possible dose as I had been in a zombie-like state for two weeks. Here is where it gets rough. I am in unbearable pain like never before. My feet and calves are aching so much I can't sit still. The pain is intense. I was not in this amount of pain before starting this drug as it had mostly been alleviated with Orencia. My doc put me on Cymbalata for dysthemia. I only wish I was not suffering so much. I will try the lower dose if I have the chance as I did notice my mood immediately lifted while on this drug briefly. I quit talking on the phone and socializing as I have no stamina and a hard time listening to others grievances. Sometimes in my case I just want to be happy if only for a little while. I have no stress in my house, so it is especially hard to commit to being out only to have my spirits squelched. F 52 15 days
60 mg 1X day
12/17/2018
Email
 3  Depression and Chronic Pain Low sex drive. If I miss a dose, I am screwed! It is a double-edged sword for sure! I am currently out of the medicine because I am a Veteran. The VA doesn’t respond well if there’s a hiccup. I have waiting for 5 days for a refill, I may not make it... Take it off the market yesterday! M 55 5 years
60 MG
12/12/2018

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