CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Manic Depression Sweating, dry mouth, anxiety, brain zaps, severe brain pain, (different from headaches) dizziness, foggy, anger, no sex drive ... AT ALL, nausea, weight gain, throat pain and exhaustion. The side effects from coming off of this drug are much worse than the side effects of being on this med. ALL of the aforementioned side effects plus I feel like I have the flu. I have not been able to work, take care of my husband or daughter, take care of my house or even make meals on a consistent basis for the past 5 weeks while I am trying to get off of this med. I cannot think, spell, or follow through on simple tasks. The first week, I went from 60mg to 30mg - I almost divorced my husband of 8 years. The second week, I almost killed myself. the 4th week I went from 30mg daily to 30mg every other day. I am currently in week 5 of my detoxing and it has not gotten better. I cannot go shopping, people in the store are "too close to me" and I become very fight or flight. I should have been in the hospital at least twice. Thank God my husband loves me and is willing to supervise and take care of me. F 40 3 years
60 mg 1X day
7/18/2014
 2  For memory problems and anxiety Extreme tiredness, low libido Did not work for my memory problems nor my anxiety, both stayed about the same. I was on 60mg/d for a full year and then to 90 for a couple months which did nothing, so I had to wean off of it completely. Be warned that stopping Cymbalta can be very dangerous, I missed 3 doses, 3 days in a row and felt like I could have killed somebody. When I weaned off of 90mg I went to 60 and then to 30 over a course of 2 months but that is not long enough. A few days after stopping from 30mg I had very strong urges to kill myself for about a week. I knew I really didn't want to die but that didn't stop my brain from telling my body to do something about it. Luckily I have family and doctors that helped me through it. The only positive I can give this drug is that it helped me sleep when I trouble falling asleep before taking it, but it made me so sleepy that I needed a nap everyday. Now that I'm off it, I hardly ever want/need naps but my inability to fall asleep is back. F 26 1.5 years
90 1X day
6/29/2014
 2  Depression and Fibromyalgia Major difficulty having an Orgasm (this could be considered good or bad. Good, because one can perform Sex for a long, long time. Bad, because one can never get the satisfaction of completing the act.) I stopped Cymbalta for six months and went on Viibryd. I also began the type 2 Diabetes drug, an injectable, called Victoza. I was on Victoza for a year when I read that Cymbalta was now being used for Fibromyalgia. So I took one to see if it would help. 7 hours later I became so nauseous I had to run to my bathroom to vomit - I ended up puking for 15 minutes straight until I had the dry heaves. I thought perhaps I had a stomach bug so I put off taking the Cymbalta for a few days. 5 daysllater I took another Cymbalta. Sure enough 7 hours later I was running to my bathroom to puke my guts up once again. It had to be the Cymbalta /Victoza combination that made me sick. A year passed and I went to a new Rheumatologist. He recommended that I begin taking Cymbalt While I was taking Cymbalta it did seem to help my depression, but it sure did not help, nor alleviate, any of my Fibromyalgia symptoms. Also, it seemed to lose its effectiveness after I took it for some time. M 58 2 years
60 mg 1X day
6/27/2014
 1  facial pain Anixaty 1 days
at night
6/21/2014
 1  depresston I broke out in weeping and extremely painful blisters on my back. Then for the next eight months I had blisters in my mouth break one at a time. The terrible side effects are to numerus for me to go into. I was really sick. F 64 1 days
30 1X day
6/13/2014
 3  Chronic pain/depression Sweating insomnia ring in head no sex drive at all hard to interact with loved one feel like I'm just there I just stop taking this drug the side effects r bad feel a little jump this drug makes u think suicidal and I never thought about that before be VERY VERY CAREFUL wild taking this drug it might help some people but the side effects is not worth it I have been off for 2weeks now and my sex drive is in full swing I feel like a kid in a candy store can't get enough M 37 3 years
120mg 1X day
6/12/2014
 1  Major Depressive Disorder After one 30mg pill I experienced nausea, heart palpitations, total lack of ability to orgasm, insomnia (even though I took it that morning) that went for hours, auditory hallucinations. I did not take another pill, realizing that this was not the drug for me but felt rotten right through the day after taking it - head-aches, general malaise. It does work for some but it was too powerful in a negative way and I knew I could never go up to 60mg. F 46 1 days
30mg 1X day
6/9/2014
 1  fibromyalgia Memory issues, exhaustion, libido issues,weight gain, black outs and ringing in ears. When I stopped taking it I felt dizzy, had no appetite and had strange nerve zaps for months. F 28 1 years
90 mg
6/2/2014
 1  Depression Started at 30 I was fine. After a month I was upped to 60 mg. A week later I started getting agitated easily, my hair is shedding way more than usual. I sweated like crazy, I felt even more depressed than ever , I became anti social and my anxiety worsened. I'm currently being weaned off this drug, while on Prozac. IF YOU ARE HAVING PROBLEMS TALK TO YOUR PSYCH ASAP DONT STOP TAKING THIS MEDICINE BY YOURSELF *** warning extreme consequences GOOGLE IT (cymbalta withdrawal) luckily I'm one of the good ones tho F 18 2 months
60
5/30/2014
 1  pain, anxiety, depression slurred impaired speeh, crying, exhausted, emotional instanility never take this drug. It fries your brain. I've been off for 6 weeks, and still cannot talk correctly. Crying and anxious all the time. Still cannot sleep 8 hours. F 63 500 days
60 1X day
5/19/2014
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 1  GAD/ Deoression This drug has been a nightmare. I have woke up every night with a feelingbof panic and cant sleep for more than an hour at a time. Even taking Ativan at night doesnt even touch the anxiety. It is the worst drug Ive ever tried. F 35 5 days
20
5/18/2014
 1  fibromyalgia and back pain inability to have sex headaches nausea will not go away after being offered for 2 to 3 years M 64 2 years
90mg/30mg
5/16/2014
 1  Pain, anxiety Never ever take this. I was up all night with panic attacks, sweats, shaking, dry mouth, feeling sick, dizzy, faint, memory loss. These are prescribed far to easily and are awful! F 18 1 days
5/14/2014
 3  depression, early dementia Shock from paying $273 for one month supply of generic. Want to change med M 67 2 years
90 mg
5/11/2014
 5  panic attacks, anxiety Side effects- jumpy,nervous,hair loss.blurry vision. Big reason I stopped.was on it over ten years.it kinda ran its course. F 56 1 years
60mg
5/4/2014
Email
 1  Anxiety Nausea, extreme night sweats, strange sensation in my head, can't sleep. F 40 5 months
60
5/4/2014
 3  Depression, anxiety Only a slight headache and maybe curbed appetite. I feel a little better on day 2, but it is early on to identify if correlation. Perhaps I'll add another review after more time. F 26 2 days
30 mg a da
5/3/2014
 1  Depression & Anxiety 2 hours after taking a 30 mg pill I felt very weird & out of touch! Also felt tired & nauseated so layed down & fell asleep for an hour & now I'm wide awake with a headache, ringing ears, & restless legs while still feeling strange & not myself. Will never take another cymbalta inmy life! F 26 1 days
30mg
4/27/2014
 2  Depression and pain On and off sweats, nausea, jittery, eyes feel like they are over focusing, dizzy. Horrible side affects but made me more tollarable to life, unfortunately I'm stopping this crap before I freak out. M 29 1 days
60mg
4/17/2014
 1  Depression Major anxiety, brain 'fog' - couldn't remember words while speaking I felt that this medication was horrible for me; coming off of it was even worse-had so many horrid side effects getting off of it F 39 6 months
60mg 1X day
4/11/2014

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