CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Fibromyalgia Sweating - couldn't exercise at all because the smallest effort left me drenched and unable to cool down. I have other symptoms such as wieght gain, indigestion, what someone else called brain zap but I take other medications and can't be sure which causes them. My doc didn't correlate the excessive sweating to the Cymbalta for a long time. I does control my fibromyalgia. I am supposed to be at 120 mgs, 60 twice a day. I am currently on 90 due to my insurance having limits on how many pills they will allow. 90 doesn't work as well but it's better than 60. I've tried Effexor but it affected my sleep. I used to be on nortriptylene for a long time. When it became ineffective, I switched to cymbalta. I don't know what I am going to do if I am no longer able to get it. I am very sensitive to sleep problems - vivid dreams. F 51 5 years
11/30/2009
 3  depression and anxiety can't maintain erection, decreased libido, a little tired, jaw feels funny towards end of the day, it has helped rid me of anxiety and the depression is slowly fading away. Currently on 30 mg moving to 60 mg tomorrow. M 37 6 days
11/30/2009
 5  Depression & Anxiety The only side effects I have are a little increased sweating and loss of libido. Cymbalta, which is an SNRI, seems to help me better than the SSRI's like Prozac, Zoloft, and Paxil. Cymbalta knocks my anxiety right out and just relaxes me. It's a very well-tolerated drug for me with very mild side-effects. It also seems to give me energy as it keeps my seasonal depression at bay. I love Cymbalta! oh yeah, it is also cheap without insurance, about $120 a month for 30 days of 60 mgs. M 27 2 months
11/29/2009
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 3  Anxiety; mild Depression 15 lbs weight gain in 7 mths; some tiredness; Major sweating to the point of embarrassment; less concentration and focus It works like a charm in the beginning for my anxiety. I am now trying to wean off this medication due to weight gain and cost. Started at 30 mg. then went to 60 mg. My doc wanted me to go to 90, but I did not want to. The doc also told me that this med was less likely to cause weight gain compared to other anti-anxiety meds - not true for me. Plus I have some muscle pain and she thought it would help that, which it did not. Trying to wean off is aweful! I ran out and had to go a day without it and had the worst day ever - brain zaps, dizziness and uneasiness. That was when I decided to ask about weaning off. My new doc has prescribed Prozac and wants me to try to wean off Cymbalta in about a week. I have been down to 30 mg. for about 2 weeks. I am going to take it slow weaning off especially after reading so many comments about side effects of weaning. I think it helps to add 20 mg of Prozac to the 30 mg Cymbalta while weaning. I hope this works for me and hope Prozac works without weight gain. F 49 8 months
11/27/2009
 3  Anxiety/Depression Brain Zaps. Dizziness. Loss of sexual desire. Inability to orgasm. Loss of Concentration. I started taking and immediately started suffering brain zaps. If I missed a day, the brain zaps were almost debilitating. After about 3 months, I was no longer interested in having sex with my wife. When I did, i was unable to achieve orgasm. I experienced loss of concentration when speaking, had to search hard for the necessary words. I was taking 90 mg daily and decided to wean off the drug. It took 3 months of consistently lower doses to get off. The brain zaps were severe and the mood swings were almost unbearable during the weaning period. I suffered frquent crying spells and greater depression than when I started taking the drug. I experienced severe feelings of hoplessness and occasional thoughts of suicide. These symptoms went away as the drug left my system. I still have occasional brain zaps 3 months after being off the drug but it is much better. M 42 1 years
11/26/2009
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 3  Depression, Social Anxiety, I have had very few -but very noticable side effects, including but not limited to: complete exhaustion (but this was there with the depression), constipation, sick to the stomach and have had changes in eating patterns. I do feel flat (as people stated) but to me this is an improvement over mania and being all over the place. I am peeing all the time and am very very thirsty. I have also aquired a taste for alcohol which I find very odd - I am not much of a drinker anymore and it is like I am developing a problem to the point people have noticed. Even though I am exhausted, I am sleeping so much better -I fall asleep much easier and I don't wake in the middle of the night anymore. I lost five pounds the first month, which is great. I have had a increase in sex drive and my migraines have gone from 3 a week to once a month. Being flat allows me to better interact in public without the anxiety but I am still depressed while alone. I am one week into the 60's. F 37 2 months
11/25/2009
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 5  Fibrymyalgia, depression, anxiety I've had some brain fog. Searching for words when I'm talking and I can't seem to come up with the right one; I've been bumped to 90mg and fee better than I have in years. I call it the greatest thing that's happened to me. I can function like a human being. F 58 1.5 years
11/23/2009
 1  Depression/Anxiety When I first started taking cymbalta I would wake up drenched at night from sweating. I felt like I was in a fog the whole time I was on this medicine. I was at 60mg and then dropped to 30mg for 2 weeks then stopped taking it. The withdrawl from cymbalta only took about a week for the dizziness to stop. I am still having brain zaps here and there, and my anxiety has returned. I would rather live like this though than be in a fog. It has only been two weeks since I stopped taking the med. If you do not feel like this drug is working, or any other AD please tell your Dr. I was on this drug a little over a year and in that time I continued to get worse contemplating suicide more than once. I had taken other AD's prior to taking cymbalta, but never experience the awful thoughts and feelings like I did with cymbalta. I now know why there is a black box warning on these meds. Cymbalta changed my whole thought process, I felt like I was in some sort of hell and couldn't escape. Now that I am no longer on this med. it is like day and night, I finally feel good again. F 38 13 months
11/23/2009
 4  Mild depression/Generalized Anxiety Foggy, tension through jaw neck and shoulders, sweating I just started taking 30 mg of Cymbalta 3 days ago and almost stopped immediately because of the comments left on this forum. I continued however because I realize that people are less likely to leave positive feedback in any situation. So, I'm here to say that if you've just started stick with it...my worst side effects only lasted a day. And already I feel better, have more energy and in general feel like a wait has been lifted off my shoulders. I know from experience that you must try several different meds before you find the one that works for you, so if Cymbalta's not working for you talk to your doctor right away and try something new. Thankfully, after several different types and combinations of meds I have finally found something that works for me. F 28 3 days
11/22/2009
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 5  anxiety I am always tired! other then that, no side effects since the first couple of weeks when i began the medication back in december of '07 I think i've always been somewhat tired so i cant blame it all on cymbalta. however the medication has helped me so much with my anxiety. my sex drive has decreased but my orgasim has gotten more intense, especially after going from 30 to 60mg. I hate beng tired all the time, but i am more calm and i hardly get worked up. i can cry and have regular emotions though. sometimes i feel weird and i cant explain the feeling, but i think its normal. M 26 2 years
11/21/2009
 1  Fibro pain disorder I got off cymbalta 60mgs and slapped my boyfriend, anger, rage, cut my wrists, feel like a zombie, no emotions to severe anger/rage. I have never had any of these behaviors before. I slapped my boyfriend during 3 different arguments, several times in the face. I have never hit anyone ever, much less someone I love. Do not take this drug and get help to wean off of it. I am a total zombie, cannot think, remember anything, feel worthless, and totally scared about these ugly behaviors that I cannot seem to control. I had to go cold turkey because I could not get the drug anymore due to financial problems and I don't know what to do to help myself in this situation. Can anyone offer any suggestions. F 40 4 years
11/21/2009
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 1  Fibromyalgia Haven't slept in three days. Terrifying hallucinations when trying to go to sleep, jaw clenching, "brain fog", feel like a zombie-no emotion at all. No appetite at all. I have tingling and spasms in my legs but think that is from the fibro. Waiting on a call from my doctor to find out what to do. F 43 3 days
11/19/2009
 4  fibromyalgia inability to have an orgasm I've been taking 60 mg for 1-1/2 years. Cymbalta dramatically improved my bodily pain levels from the fibromyalgia. I also have arthritis, but that is not reduced at all. The orgasm issue is frustrating. Sex is still enjoyable, however. I've recently added Wellbutrin to try to counteract that part of it. F 54 1.5 years
11/18/2009
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 1  depression dripping in sweat all the time, extreme fatigue, mucus coming out of my anus, feeling like I have to have a bowel movement several times an hour, constipation, and my depression is the same as when I wasn't on it. Also feel like I'm in a cloud allthe time. Having vision problems. DON'T TAKE IT!!!!!! F 36 6 days
11/17/2009
 1  fibromyalgia This stuff I wont call it a medication, is the "Devils Brew" for those of you who have yet to experience side effects, get ready they are on their way. I took this medication for 7 months and previously posted the hideous side effects and horrific withdrawal.It has been 11 months since I took the last dose and I havent felt like myself since before I took the first dose. It takes your spirit. If you are on it STOP if you havent started DONT. F 63 7 months
11/17/2009
 4  stress mild constipation M 38 2 weeks
11/16/2009
 5  major depression No side effects. Now that I've just finished tapering off after 4 years of use, I'm experiencing some light-headedness/dizziness, fuzzy-thinking & nausea. This medicine saved my life. F 28 4 years
11/15/2009
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 4  Depression, Anxiety Nausea, Diarrhea, constipation- stomach issues. The first few months, I experienced headaches and fatigue. When I began Cymbalta, I had to take naps frequently. Also, I felt like I was in a fog most of the time. Later, I experienced constipation. Now, it's nausea everyday and diarrhea a couple days a week. Overall, it has definitely helped with anxiety. F 24 11 months
11/15/2009
 3  Fibromyalgia pain & Depression I've been on 60mg Cymbalta daily for 2 years. Recently decided to increase dose slowly. Anything added to my 60mg causes red burning & itchy butterfly rash on face. This has worked well for chronic pain.Unfortunately I can't seem to take more than 60mg because I break out in serious hives on my face in the cheek and eye area. I seem to be more weepy (crying easily) during pms as well. F 41 2 years
11/15/2009
 1  chronic fibromyalgia pain after being on the drug for three months my family, friends and relatives urged me to take a good look-I had become agressive headaches, exhaustion, no major pain relief -coming off the med was unreal, I am into the fourth week and I feel like I have no energy, every part of my body hurts plus to touch me I feel pain- I cannot do adl's and frustration leads me to cry. I want to go back to work but every day that gets farther away. I was prescribed the med but was told my ultram was ok to take with it-major negative and now I am paying for it F 57 90 days
11/14/2009
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