CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Pain This should have been yanked or never approved by FDA in the beginning. Worst side effects ever. Been off 2 years. Side effects never seem to go away. They can take there tv ads and put them where the sun don't shine. Also the doctor who prescribed it, was an incompetent. When I terminated use, it was good luck you are on your own. F 55 2 months
60 1X day
4/6/2012
 1  depression Getting angry and staying angry over things that didn't warrant it. Suicidal ideation began in June,2011 Extreme sensitivity to sun began in May 2011. The sun would make me sick and angry. Depressed and high at the same time. Strong sense of hopelessness and apathy even though I was working hard at the same time. Increased cravins for sugar after 1 year Depression deepened after suicide attempt. Hot and then cold throught the night. Going off the stuff is NOT fun. I've had brain zaps, nausea, vertigo, body and muscle pain, irritation and rage, and many other symptoms. F 56 18 months
30 2X day
4/3/2012
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 1  oteo artheitis pain memory loss, fuzzy thinking, balance off, dizziness, fatigue It does help relieve pain however in joints F 76 2 years
1X day
3/29/2012
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 3  Bipolar depression nausea dry mouth constipation the only reason why i'm giving this a 3 and not a 4 or 5 is because it is not a good med for those with bipolar who are prone to mania. the pro of cymbalta is that it made everyday activities more tolerable/conquerable and even enjoyable. however, it made me feel manic as well, which gets old after a while because there is no balance. I felt like maybe i was being numbed and i really just think that people with bipolar shouldn't be on anti-depressants. however, if you have clinical depression and lack motivation to get everyday things done, then i think cymbalta could be like a breath of fresh air for your life. again, it can make you feel manic or strung out, so not everyone should take as high of a dose as i did. F 24 1 years
60 mg 1X day
3/27/2012
 1  Anxiety dizziness, nausea, "brain shocks" I started to take because of stress at my job and increasing anxiety on a daily basis even when not at work. I started to feel better- I didn't sleep much but felt more "alert" and awake initially. I started at 30, eventually up to 60 and was good there, when Dr prescribed 90 I asked to go back down. Did not like 90. felt suicidal. I exercised 4+ times a week and didn't understand why the scale didn't go down. I had a decent shape after 4 months of 4x's a week exercise but wouldn't lose weight. i am still baffled on this. When I stopped exercising because of a job switch and lack of time, i gained 20 lbs rapidly. i am back to exercising 2x's a day, 3 times a week and still no weight loss but no gain either. I do hate this drug and have tried to get off for a year now. If I miss a day, i am so sick and nauseaus. That doesn't even fully describe it. i do not think anyone should ever take this drug if another option is availabe. I was weaning off as dr ordered but still not quite there. I am trying something new starting tomorrow because my anxiety is getting worse and depression is starting up again. My mother took for fibro but had to go off. She hated teh way she felt. i would not recommend this to anyone F 35 3 years
30 1X day
3/26/2012
 1  Osgteoarthritis Dizziness, vomiting, uncontrollable diahrrea, loss of muscle control, unable to walk or even crawl. My experience with Cymbalta was terrifying. My doctor prescribed it for pain contro with my Osteoarthritis. I waited till the next day to take it, as I don't like to take a new med in the evening. I began with a dry mouth and then dizziness. I lay down and when my husband called to see how I was I said I was okay as long as I stayed prone. I had to get up to talk to a client and could hardly make t to the computer room for dizziness. I hung up on him due to feeling so bad and lay down on the floor to try and stop the dizzies. I began throwing up and then lost control of my bowels. Called my husband to come home and my daughter. She stayed on the line till he got home. I crawled to the hall as I couldn't walk and she called an ambulance as directed by the doctor's nurse. I was dehydrated and had stage 4 blood pressure. I don't remember the 45 minute drive to the hospital. I would NEVER recommend this drug. It is quite capable of killing. Had my husband not gotten home I would have gone into a coma and possibly died. This is a case of the cure being worse than the condition it is supposed to cure. Oh and my doctor wanted me to keep the samples to try again later.....Not a chance. I am now doubting how trustworthy he is. F 65 1 days
1X day
3/23/2012
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 4  LBP (Lower Back Pain) Dry Mouth, Night Sweats Been taking Cymbalta for 2 weeks, started @30mg 1st week then @60 now. Back pain went from 6-8 level to 1-3 level. Very happy about that, am able to function in all areas. Concerned about the long time effects concerning sexual reactions. I already take 3 blood pressure pills (for 11 yrs) to keep my #'s low. prior to Cymbalta M 43 2 weeks
60mg 1X day
3/22/2012
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 1  Fibromyalgia/Depression Every side effect you could think of. The brain zaps are what really scared me, my doctors thought I was crazy when I explained them, then after 2 years of this and other symptoms I did research and found other people experienced the same things. Thank goodness I wasn't crazy. ALSO, bad constipation, I think it brought on my IBS that I am now dealing with. Previously, I did not have very many stomach problems, after being on Cymbalta for 2 years I have so many issues with my stomach. The withdrawals from this medicine are even worse, I thought I was going to die. I didn't realize it was the reason I was flipping out until a couple weeks later and I got on the internet and found out it was withdrawals of Cymbalta! I cried nonstop for 2 weeks, and begged my pharmacist to help me, I thought I was having a reaction to another medication, thats when we discovered it was the Cymbalta! DON'T take it, I thought it was a miracle drug because it helped my Fibromyalgia pain a little, but forget it, it's not worth it. I'll take the pain anyday! F 48 2 years
120 mg 1X day
3/21/2012
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 1  Chronic pain/Depression The only side effect was a monoemotion state, which sucked. Hell to get off of, which I did AMA. Much uncontrollable sobbing. When I started thinking about suicide, I was able to reason with myself and remind myself that this was just withdrawal from that godawful stuff and that it'd be over fairly soon. I didn't notice any difference in my pain level as a result of stopping the Cymbalta. I also didn't notice any effect on my pain level when I started it. Pharmaceutical Co. are way too good at pushing their drugs, and maybe in getting other treatments killed, like Medical Marijuana. Just like GM did to the electric car. Medical Marijuana has helped improve my life while getting me off of meds for spasticity, nauseau, depression, acid-reflux and who knows what else. I feel so much better now than when I was taking all those pills, Which was when I was in the hosp. for 9 mon. and rehab for 5 1/2 mo. I still get sick quite often, but I can eat some and laugh at something funny on TV. I wouldn't take Cymbalta again, or any other anti-depressant for that matter. M 46 4 years
60mg 1X day
3/20/2012
 4  anxiety and depression at the start i felt dreadful even on the 30mg nausea, head spins, then onto 60mg similar symptoms but after a week I felt fantastic as if I had my life back. no more sadness and racing pulse or feelings of inadequacies. I had no more suicidal thoughts. After four months i started to feel unwell. A fever started and then the diarrhea. One night I went 14 times. Every day for 3 weeks. I have lost 5kgs. Doctor thought it was a bug. Negative. Blood test showed increased levels of something which meant I had an allergy to something. I think it was the cymbalta. I weaned myself off over about ten days. Last tablet yesterday and 6 trips to the toilet today. i can't take much more of this. i just hope it is the cymbalta and not something else. F 52 4 months
60 1X day
3/17/2012
 2  Depression Withdrawal complete hell Not worth The numbness of life F 45 3 years
120
3/17/2012
 1  Depression/Anxiety Drowsiness, lethargy, hot/ cold sweats, dialated pupils, tremors, nausea i was reccommended this drug as I was concerned about the side effects of others I had tried ( Effexor, lexapro) affecting my work, thank goodness I started this on my day off as it has been pure hell WORSE SIDE EFFECTS than the others!! Not taking another dose as cannot take the time off work to push through the side effects, don't know what to do now... F 26 1 days
30 mg 1X day
3/17/2012
 3  Fibromyalgia/Depression constipation, no sex drive, flat emotions, lack of interest Although Cymbalta helps the Fibro and Depression the side effects are quite bothersome. Terrible constipation - make sure to get 8 glasses of water, 35 grams fiber ea day, still need to take stool softner. What I hate most are: the loss of sex drive, flat emotions and lack of interest in life. F 56 5 years
60 MG 1X day
3/14/2012
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 1  Bipolar II SNRI's are not for me I found out. At first I was on 30mg and felt alright but because of my anxiety my doctor tripled my dose and it threw me into severe mania and I had to be hospitalized. I don't remember the first two days after the second day of taking this large dose. Its probably more of a testament to my former doctor than the drug itself. He refused giving me Lorazepam and tripled cymbalta...idiot. My pharmacist stated this drug is the best for improving mood, sadly I didn't get the opportunity to find that out. F 42 30 days
120mg 1X day
3/11/2012
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 5  Intense pain from broken neck Add a lowwer level of pain relief and calmer aniety. Pain grew just before the actual neck surgery. Five brokens bones were removed from my neck before repair begainl Further repAIR IS needed but a new nuroulogist is needed for the work. What Pain pills safely work wirh cymbaltal when there are so many other brothen bones not being atteneded to'I hade the broken neck for 10 years and workers comp refused to provide necesssary care. [email protected] F 60 6 months
60mg 1X day
3/6/2012
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 1  neck and shoulder pain No initial side effects. Noticed less pain a day or two after starting, but after taking for two months pain started to increase and I didn't want to continue taking pills the rest of my life. I stopped taking pills 6 days ago and HATE the side effects it's giving me now. Dizziness, not being able to sleep through the night, weird dreams and today (day 6) crying at anything and everything. The dizziness is the worst thing..it wears on you. I would never again take this medication and definitely would not recommend anyone taking Cymbalta. F 46 2 months
30 mg 1X day
3/6/2012
 5  Severe Depression slight headache. Best to start really low and work up. Otherwise, am fine with loss of appetite. Gave me back my life. Feel lift of mood at 90 mg. At 30 mg and 60 mg, just happy to stop crying. F 55 1 years
90 MG 2X day
3/4/2012
 1  Mild Depression Insomnia, Vivid dreams when I did sleep, Spacey feeling, No sex drive I couldn't take the spacey feeling. I was forgetfull and couldn't concentrate. I went off cold trukey, which I probably should not have done. Horrific withdrawls for the short time I took it. It's been 2 weeks off of it and I feel agitated and cry all the time. I didn't have those symtoms before I took the cymbalta so I don't know why I have them now. I would not recommend this drug to anyone. F 52 3 months
60 1X day
3/4/2012
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 4  Fibromyalgia Initially yawning but that stopped after two weeks. I had been on Cymbalta for 2 years and had to discontinue due to "poop-out". Tried Pristiq which made me feel wired and didn't do anything at all for FM pain. Tried Prozac which made me feel emotially flatlining and killed my libido. Now, after 1 year off I am giving Cymbalta another try. It has been working very well so far and I am so relieved...! Combine with 100mg Tramadol if the pain gets severe. F 42 6 months
20 3X day
2/29/2012
 4  major depressive disorder first few days was horrible! i had insomnia and weird dreams which was terrible. my suicidal thoughts increased severely and i felt nausea, sick and so surreal. My sex drive decreased dramatically. Also on the third day i experienced dilated pupils which was strange but that went away 2 days later. After a week though the side effects have decreased however my mind still feels a little strange, but my sex drive have come back! yay! This AD has helped me a lot. I'm satisfied with this however i missed 2 doses the last few days and now i'm experienced brain zaps and all i want to do is sit down and not do anything at all. So strongly suggest you don't miss any dose. Again, this has done miracles for me. Still feeling a little strange, but i can feel myself getting better as the day progresses. F 18 1.5 months
30mg 1X day
2/29/2012
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