CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Fibromyalgia, Depression Nausea was horrible for first 6 months, since then bloating, unsettled stomach, have to take in morning because caused insomnia, periods have been increasingly irregular since on this medication, eye fatigue/blurry vision...difficult to explain F 29 2 years
60mg 1X day
6/16/2017
 1  Chronic pain & emotional tension Horrible! Waking in night and making incoherent phone calls to friends, halucinations (more severe & disturbing than LSD- being honest), disoriention.... One drug that Health Canada MUST pull! Please report ANY side effects promptly to your Dr. Lilly & Health Canada! Just don't take this please! M 59 2 months
6/10/2017
Email
 5  Depressed High blood pressure F 0 days
30
5/1/2017
 1  Depression No sex drive , sores on my head and body, light headed, cant remember things feeling tired all the time,shaking, fingers twitching I don't WANT this medicine anymore I would not recommend taking cymbalta F 59 2 years
60 mg ×2
4/26/2017
 1  Pain Management and Anxiety It immediately caused severe​ problems with concentration, blurred vision, upset stomach, and angry mood swings. It also caused problems with total lack of sex drive and caused overwhelming emotional problems. What makes this medication so bad is the 12-hour half life which I am sure you will read plenty of posts about. I hate this drug and anyone who prescribes it because they obviously haven't read any of the patient reviews. It looks like half of the people that take it have problems and the manufacturer failed to devise a plan to come off this medication. Also the manufacturer does not require the prescribing physician to advise the patient of the guaranteed side effects and addictive properties of this medication. This junk may have cost me my jo. Fortunately I can see a little bit of difference one week after discontinuing use. I will be calling a lawyer. No wonder the FDA did not approve their new drug for 2017 for Eli Lilly who invented Cymbalta and heavily advertised the drug without disclosing accurate side affects and withdrawal syndrome for people like me that had a bad encounter with this "medication". I would love to see all of the management for Eli Lilly forced to take this medication as they have advertised for a year and then cut them off completely so they will learn the real side effects of this drug that they so heavily advertised. I would pay good money to watch each person's life fall apart in front of their eyes. Whatever happened to the code of ethics that the scientists and doctors that work at Eli Lilly. I also have a real problem with the way this medication was dispensed at my Pharmacy and how there were none of the required FDA warnings on the any of the bottles that I was prescribed. What is wrong with doctors in America today. I tried to tell my doc M 50 2 months
4/21/2017
 5  Pinched nerve Lower back - anxiety Had to take pain pills before I saw the commercial for this Med - a life saver I was taking opioids for pinched nerve in lower back & going to the pain clinic once a month before I saw the commercial for this med - as soon as I saw it - I went to the Dr to ask about it - have not had to take a pain pill since :-) I can still feel the pressure sometimes in back back from the pinched nerve (when it's really cold) but I dint feel the pain anymore. Stopped the pain on the 1st day . I was taking Zoloft - with horrible side effects - was able to swap straight from the Zoloft to the Cymbalta without weaning . Helps anxiety , gives me energy . Once the generic came out , it did have to up the dose 30 Mgs a day but had to do the same thing when the generic for Zoloft came out . I think this med was made especially for me :-) F 49 5 years
90 1X day
4/14/2017
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 1  Anxiety and Depression Extreme weight gain (40 lbs) Numb. Not my limbs, but my emotions. Hearing loss and tinnitus. Decreased sense of smell. Loss of sex drive. Loss of sexual pleasure. I wouldn't recommend to anyone. It took me three YEARS to wean. Finally weaned with the help of Zoloft. I hate this drug and doctors who prescribe it. F 34 6 years
60 mg
4/9/2017
 3  Rheumatoid Arthritis pain, anxiety Asked for something to help with ongoing anxiety and depression (and peripheral mild pain) all due to Rheumatoid Arthritis that's been exasperated with being laid off and impending shoulder replacement surgery (due to RA). I'm a very healthy (outside of RA), work out regularly, but have been single since divorce in '99 (no kids). I've always dealt with life alone and somewhat successfully. But approaching 50 y/o, a chronic illness, and trying to find viable work in a town of only 70k is daunting. Rheumatologist suggested generic Cymbalta. At first felt more calm, not anxious or quite as worried of the future. Then sleep issues (waking up 2-3x night), and feeling my emotions were subdued began. Then lack of sexual desire with gf. Decided my symptoms weren't bad enough to warrant need for Cymbalta. Took half of capsule contents on night #9 to taper. Then next night (last night)...none. I feel more myself already on day 11...no ill side effects I've read about. Didn't give it the recommended 2-3 weeks for full effect...but the withdrawal effects from long-term use I've read (and confirmed by my rheumatologist) and preferring not to be emotionally numbed are main factors of stopping. Many of you have debilitating depression that warrants a med like Cymbalta...but it's not for me as my symptoms aren't as dire, thank God. I'll have mild anxiety though..and will have to deal with it, unfortunately. All...regarding the morbid side effects upon discontinuing, take everything you read online with a grain of salt. ALWAYS consult your doc about side effects when stopping...and of course, don't stop without your doc's instructions and awareness. Finally, something rarely addressed with depression...regular exercise is a secret weapon against depression. It works! But you must be patient and give an exercise routine several months to work. Doc's never instruct this option. M 49 9 days
20 mg
4/4/2017
 3  Fibromyalgia Extreme sweating around neck at night and during day around head hairline Taking it for fibromyalgia F 68 6 years
90 mg
3/29/2017
 1  For post natal.depression and post I never twigged just realised. A consultant upped because its suppose help bladder problems.Kept going to doctors got.awful vision disturbances. Stomach problems and put on 3stone and have tried to lose weight couldnt understand why now I know. Great drug in the beginning it really helped now been.on it for 17 years. The bladder specialist to do the test need to be of it so told me to drop by 20 mg. I wonder was wrong with me.Stomach problems horrendous visual problems headaches.Weird electrical feelings and feeling not there.More aches and pains.Hot flushes Now read up on this drug and halved the beads inside. Realising you just cant stop this drug.I am know going to gp to sort this and come off it totally Whether I will ever get my vision back I dont know. Beware F 10 years
3/5/2017
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 4  Depression I started taking cymbalta some 5 yrs ago , @ 60mgs daily , with some good results however over the last 6 moths having been having son difficulties with life in general & pain associated with diabetes, hence dosage increased to 120 mga daily divided dose , this has help me in general attitude to life & getting pain free mojo back again , so far all good , allow sufficient time /rest to take effect, cheers pjf M 70 5 years
120
3/4/2017
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 1  Anxiety and depression When first taking it, it help a little but then not at all. Depression never went into remission and the anxiety just got worse and worse. Went off Cymbalta about 5 weeks ago and it has been the worst withdrawal hell!! Sweating, cannot sleep past 5 AM. Anxiety so bad there are days I am incapable of calming down. Weight loss also. What a howwible experience. It is just downright scary! I would not recommend this drug to anyone. I am now doing acupuncture and supplements. The memory issues are awful. Confusion, crying. They say it will take 3 to 6 months to get rid of the withdrawal symptoms. F 70 7 years
40mg 1X day
2/25/2017
 1  Depression Horrible. Do not take.. I had every single side effect possible including the call your doctor if you experience! The problem was I didn't read about this medication until my health was turned into an uproar. I had chronic migraines, lost my period, hair, became diagnosed with fibromyalgia, became diabetic, thyroid issues, eye twitches, vision change, change in sleep, digestive issues, memory issues, such much more, but basisly felt like death. That's when I was thinking I was knocking on heavens door. I decided to see an Eastern med dr and he advised a 5 day lemonade cleanse. Immediately starting I got even worse symptoms, but I stuck through due to my body needing a candida cleanse from such intense sugar and carb cravings. My mom, my primary dr and I realized I started the cymbalta in nov and the Side effects gradually became worse mid dec. The cleanse symptoms were actually withdrawl symptoms that I am now on day 6. The company and other sites state 2 weeks and it's a withdrawl jus F 36
1X day
2/19/2017
Email
 1  Migraine Worked fairly well till I got serotonin syndrome. Went from 60mg to 30mg then every other day. Withdrawal is hell. Sweating, anxiety, overall pain, shaking, can't function. This already for 3 weeks. I hate it! Doctors needs to warn you about withdrawal also. F 52 4 months
60mg
2/16/2017
 1  Fibromyalgia depression/PTSD insomn Nuasea migraines dizziness loss of appetite feeling full quick diarrhea worse insomnia restless goofy within first two hours of taking it and then I would crash and get back up. It was really horrible I was taking it for nerve pain and just made it much much worse. I kept telling the doctor, and she said to wait and up the dose to 60mg well now it made me have an unexpected period and I feel like I have poison running through my blood whatever the doc says I'm stopping this F 19 3 weeks
60mg night
2/15/2017
 3  Depression None Too freely prescribed F 62 1 days
2/11/2017
Email
 1  Fibromlagia 30 mg didnt seem to be helping with fms pain so was advised to rake up to 60 mg thats when my problem started heart palputation emergency evac by rfds and diagonised with af doctor does not seem to think cymbalta caused the af but it was probably the trigger massive headaches,dizzy and nausea when stopping never taking this med again very bad experience F 52 3 months
30mg
2/6/2017
 1  For spinal stenosis pain in foot Severe nausea, chills, itching, insomnia, high blood sugars, exhaustion, headache I'm extremely sensitive to drugs and obviously to cymbalta. Only one pill caused all these symptoms. I'm on day three and think I'm getting better, but can't get out of bed or a chair from exhaustion. F 63 1 days
30 mg 1X day
2/6/2017
 5  Pain,anxiety I feel calm ,energy M 46 1 days
20
2/4/2017
 1  Nerve pain Colon stopped working Never should be on the market F 4 days
30 mg
2/1/2017

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