CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

Filter Results

Compare CYMBALTA with similar:
 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138


More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  fibromyalga (sp?) some nausia at first, some constipation I've lost 20 lbs!! sleep really well at night now. I have moments of being tired, but they pass. some headaches, but i had those before Cymbalta so I really can't say. the pain is WAY down - using along with TENS unit. NO paid meds needed now. I feel more on an even keel. My car accident was seven months ago and I feel really good! I ran out of meds and suffered confusion, vertigo, loss of control - but got back on and things have been great! F 40 3 months
9/15/2009
 4  Severe Depression Urine retention, vivid dreams, loss of appetite (which is a good thing), minor stomach problems It seems to be working quite well for me. My mood has definitely been elevated since I've been on it. I had been on other medications but they had not been working as well. I am taking it in combination with Welbutrin. M 64 2 weeks
9/14/2009
Email
 1  Depression, anxiety, fibromyalgia, Heightened anxiety, increased depression, listlessness, apathy, emotional numbing, increased physical pain! My pdoc and I decided to switch to 60mg cymbalta from years of being on Effexor XR 300mg(which recently seemed to "poop out" on me). After 4 weeks on 60, began a steep slide back into a state of depression I haven't experienced for many years, so was upped to 120 mg in mid July. I just began 100mg Pristiq today, since Cymbalta clealy did absolutely nothing for me other than put me in a dangerously depressed and pain filled state. I feel like a total zombie, can't do much but get in and out of bed to go to the bathroom. A constant feeling of background dread - a shadow of my former vibrant self. I feel totally disconnected and struggling to get through each day holding on to the hope that I will wake up feeling better and able to function normally again. F 42 3 months
9/12/2009
Email
 1  Intractable Depression Need to sleep 10-20 hours / Exhausted / Wild nightmarish dreams / Teeth grinding, jaw clenching, tongue biting (seizures) / Urinary retention / Severe diarrhea / No motivation, social isolation, lack of any feeling / Severe Irritability / Inability to function / Don't care about anyone or anything / Chemical Castration / Dry mouth / Tingling and numbness in limbs, painful feet / Extreme Fatigue / Memory Loss / Vomiting / Carb Craving / High Blood Sugars and others as previously listed by other posters I have suffered from severe depression for many years following the onset of diabetes and loss of career. I have tried most of the usual antidepressants on the market with no improvement to my depression. Approximately 4 months ago my psychiatric nurse put me on Cymbalta, starting with a 30mg dose (have since increased through 60, 90 and 120mg). There was no benefit to my depression at all And the worst side effect has been the desire to sleep 10 - 20 hours a day and then total apathy about everything and anything. Have been stuck for weeks in a completely flat emotional state...letting everything go including my diabetes. I recently became ill and nauseated...causing me to stop taking my meds...including Cymbalta. I am now suffering with the worst of withdrawal symptoms as frequently stated throughout these postings. I am afraid I will have to be hospitalized. If I had known about any of these terrible side-effects, I would never have agreed to take Cymbalta. I believe it is a very dangerous drug. I believe it should be withdrawn and re-evaluated. I believe a class action lawsuit is in order here. Good luck to everyone taking this med. M 50 4 months
9/12/2009
 4  fibro & depression at first, some s/effects- nausea, insomnia, terrible headaches, but after 2 days my debilitating fibro pain was 80% better! I had swore off anri-d's for life after coming off effexor 1 yr ago, so was pretty happy with the amazing-no pain- result. It has been pointed out to me i am 'flat', i feel very emotionless, both ways, don't get upset nor do i laugh as much as i used to, appetite decreased, still the odd headache, fibro pains-gone! but im so tired... its an effort to write this! i was started on 60mg 2 weeks ago. F 38 14 days
9/8/2009
Email
 4  Depression. Fybromalgia-neuro pain Initially disassociation, dry mouth, nausea, insomnia, and very forgetful. But after 4 months taking 60 mgrs/day + zoloft 100 mgrs, the fybromalgia has improved for the 1st time since it started. The spams have quiet down. And no longer feel so depressed. As a bonus I regained my libido lost since the accident. And yes I am not in menopause the lost was due to the depressiona and the chronic pain. I injured my spinal chord in an accident 10 years ago and suffer from chronic pain as well. Cymbalta has made a difference in my lif, and find myself active and with more energy. I am glad I stay with the medicine even if I still suffer from a bit of nausea and stomach problems that compared with the way I felt since the accident,are a small price to pay. F 53 4 months
9/6/2009
 1  Depression After several 3or 4 weeks I had bad dreams and pain in my legs. On day I took 30 mg thenthe nest day 60mg with 30 I had pain in one or the other legs always moved and then the next day on 60 it was often in both lgs. I had to buy a cane and I fell from spasams in both legs at the same time. I realized it was related to the pill and a side effect that got worse with a higher dose. The leg pain stopped when I stopped the pills. The withdrawl was awful major waves in my head like dizzy can't drive or walk. I now have to restart after 3 days and take 30mg and get off very slowly or I won't be able to work. The doctor had no knowlefdge of expected side effects the pharmacist helped. I hate this pill. Hard to get off and awfull side effects pain , bad dreams and pain in my legs. F 59 3 months
9/6/2009
 2  Depression Low sex drive, stomach upset, occasional headache, emotional "flatness." Stopped this drug b/c it wasn't really working and left me emotionally flat. This is one of the worst anti-depressants I have ever come "off" of in my life. When I was decreasing the dosage from 90mg to 60mg to 30mg I experienced nausea, dizziness, migraine-like headaches, rapid heartbeat, trembling and generally walked around for two weeks feeling like I had the flu (I didn't). I would only recommend this medication as a last resort for depression if every other SSRI & SNRI have been tried. F 35 4 months
9/3/2009
 4  Depression, pain, anxiety The first few days. Insomnia (never done speed, but i am pretty sure you could compare it-wanted to go on massive cleaning spree. Nausea and sweating also occurred. After a couple of days body regulated, now the only thing I noticed, is dry mouth and an increased sex drive without the ability to orgasm. F 29 3 months
9/1/2009
 2  Depression and Anxiety During the initial 3 weeks: insomnia, body odor, restless leg, very alert, blank/emotionless. These things WILL GO AWAY if you wait it out for 4 - 6 weeks. Current side effects at 90 mg and 7 weeks: No more constipation, starting to sleep better, having some emotions return. Forgetfulness. It took 6 weeks to finally get some anti-anxiety results, and it's minimal. The depression has improved, but very mild. I get blue when I drive or an alone, but maybe that's just me. I was hoping for a med that would make me feel happy, how I used to always be - so far Cymbalta is okay, but not enough for me. I suggest asking your doctor for Trazadone to help you sleep if you're having issues. It helped me. F 32 7 weeks
9/1/2009
 4  Depression I have not had any side effects. This medication seems to work well for me...my depression is finally controlled after years of trying to get something to help! However...if anyone thinks that medication is all you need to help with severe depression, you will be disappointed... F 49 1 years
8/31/2009
 3  Depression Strange thoughts, Nightmares I have been on 60 mg for the last year and I tried to wean myself off once and it just did not work. I am 28 now and was dignosed with depression when I was 14 and took Zoloft and Prozac for 4 years. Those meds were nothing compared to Cymbalta. I can say that it has helped with depression but the nightmares and insomia are starting to really drag me down. I can of panic when I know I need to go to bed. It helps alot when I read beofre bed if not I have extreme nightmares that I feel like are too real. F 28 1 years
8/31/2009
 2  Depression/Anxiety so tired that I can not function I have only been on it like 5 weeks and wonder if I can just get off. I told my doctor about my side effects last week and he said that we should try it for a little longer. I just don't think that I can do it anymore. I think that it is definitely adding to my depression. F 27 34 days
8/31/2009
 4  Anxiety, Fibromyalgia Horrible initial nausea, then, over time, increased fatigue, short term memory problems, lack of focus. Long period of withdrawal symptoms when ended. I was initially a devotee of cymbalta. For my anxiety and fibro, it was fantastic. I didn't wake up feeling like a 90 year old trying to move since my joints no longer ached, and the constant pressure of anxiety evaporated. I was able to focus again at my job. Problems began after three months with fatigue, which by month 6 had increased to include memory problems and the inability to stay on task. I tried several medications in combination to help address the problem, which included vyvanse, ritalin, adderall, and provigil. Each worked, but had their own problems (look for other 41 year old comments posted on 8/30/09 on this site for my issues with those drugs). About 4 months ago I finally decided I needed to stop. I read elsewhere about experiences regarding withdrawal symptoms, which can be very pronounced for some with the one agreement being never do it cold, and developed a plan with my psychiatrist to minimize these effects. Over a two month period, I moved from 60 mg/day down to 5 grains taken from a capsule every two days, and then stopped completely. There were still w/d effects, such as the 'brain zaps' many note, but these were bearable, periodic and short lasting when they did occur. Including the two month plan, it was still a little over three months before all of the withdrawal symptoms vanished. M 41 1 years
8/30/2009
 1  back pain depression Insomnia headaches nightmares I started taking cymbalta 2 months ago. I have had nightmares about my car wrecking, drowning, not being able to move, my husband having an affair with my best friend, and a lot more. The nightmares make me not want to sleep. I have actually woke up and wanted to cry. And also sometimes I just can't sleep, I don't feel tired at bedtime (even though I was tired an hour before). I also have the worst headaches and while I have the headaches my right eye is blurry. And it hasn't helped my back pain at all F 22 2 months
8/30/2009
 1  Bi-Polar headache lasted for a month, insomnia, brain zaps for 2 weeks when discontinued the medication The brain zaps were weird. Just standing in a store and little prickles of electricity floating in my head...I will never take this medication again. Switched to Lexapro. F 46 1 months
8/29/2009
 1  FM Huge weight gain, bloating, could not fall asleep for 1-2hrs every night,increased sweating. Never go on this medication...aside from the side effects while taking it tapering off is worse. F 44 7 months
8/29/2009
 4  Depression Night sweats, loss of appetite, vivid dreams, shakiness, nerve-like pinching feelings in my extremities if I miss a dose. I started taking Cymbalta in place of Zoloft because I had gotten so used to it that the largest does wasn't enough, so I had to change. I've been taking 60mg/day for almost two years, and for the most part I have been happy with it. Emotionally and how I feel day to day, I can tell a difference and feel better. I do, though, have an extreme use of appetite and frequent night sweats. If I miss two days of taking it, my head feels weird and I can feel prinkles in my nerve endings in my hands and feet. F 22 2 years
8/28/2009
 1  Depression Severe fatigue, problems staying asleep, slight nausea I have been on Cymbalta for almost a week and have been in bed the entire time. It has caused me to be severely fatigued with flu-like symptoms that came on about 24 hours after beginning this drug. The depression was not as bad as I feel on this medication. I am supposed to go to 60mg in two days but after reading the reports of the great difficulty in getting off Cymbalta - I am going to stop taking it before it gets even worse. F 62 5 days
8/28/2009
Email
 3  Depression, Anger, SAD I did not experience side effects, other than maybe a lower libido. Until.....weaning! I have never been on any medication that is worse to wean from than this one. The buzzing in my head, for about 6 months now. I went to 4 doctors to find out why I was suddenly having buzzing (also called tinnitus) but no one could come up with any reasons. Finally a psychiatrist resident told me that it was a result of weaning off some anti-depressants. OMG, I am so glad to know that I will not have this horrible constant buzzing for ever. I also experienced an elevated liver function, again my doctor did not know why, but I have since read it is due to long term Cymbalta, in fact that is one of the reasons I eventually stopped taking it. Actually, I have been on it for 4 years and I am still trying to wean off, it's been 6 months, slowly tapering. I am dizzy, very depressed and at time agitated and mean. F 50 4 years
8/26/2009

Previous Page       Next Page

BACK TO TOP