CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  GAD Weight loss and increased anxiety I stayed on cymbalta longer than I should. It did nothing for my GAD and actually made it worse. I only stayed on the medicine because it helped me lose weight. Unlike others - I had no problem getting off. I went from 60 to 30 to 0 with no side effects at all. M 35 1 years
60 1X day
6/25/2012
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 1  Pms , Anxiety Horrible headaches , diarrhea within 3 days of taking it and still having it . Nauseated when eating or drinking . Pools of sweat when I sleep and morbid dreams . Was places in psychiatric hospital for becoming suicidal on this drug which I've never been before . Very irritable and sensitive emotional state , memory loss... Sleeping 18 hours a day when I normally sleep 4-6 . Antisocial feel like I have flu !!? F 25 4 weeks
30 mg
6/25/2012
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 1  Depression MY stomach burned so bad I needed to go to the hospital, I took it with food and followed all directions that came with it. It was crippling pain. M 21 3 days
100 mg? 1X day
6/25/2012
 1  Depression Oily and sweaty skin, headache, hair loss This is a nasty medicine and i recommend avoiding it at all costs. The side effects are terrible and coming off of it is even worse. I was ill for 60 days when i stopped taking it. F 47 365 days
60 mg 1X day
6/24/2012
 3   About a week into Cymbalta, I stopped ejaculating. i still have a fairly active libidio and can achieve several erections in one night, but after hours of stimulation, nothing, nada, zilch. it was prescribed for nerve pain, whici has abated some, but not nearly enough to make this worthwhile. M 62 1 months
10mg 1X day
6/23/2012
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 1  Diagnosis for fibromyalgia (ddd) RAGE, emotional instability - inability to control my thoughts expressing emotion Within 2 hours of taking one pill I was throwing chairs and screaming at everyone while the "reason" voice inside my head (and heart) were not able to take hold. I do NOT understand why the medical industry is so willing to experiment with the general public. Just look at all the side effects. Look at how people are saying "Maybe I just need to give it more time." This stuff messes with the neurons in your brain which no one truly knows what is going on. Meanwhile, because people stigmatize drug use for legitimate pain, they must suffer from not using time=tested pain medications. In short, doctors just do not want to go the lengths to take responsibility. F 44 1 days
30 1X day
6/19/2012
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 3  Clinical Depression Increased Blood Pressure. Took water pill for years for BP. Due to Cymbalta, I had to take Lisinopril too. 9 months on Cymbalta along with 1 month with Lisinopril meant dizziness and still BP that was too high. When standing up my BP would drop quite a bit which caused dizziness. Cymbalta seemed to work otherwise, but high BP had to go. I quit Lisinopril and am weaning from Cymbalta to Prozac. Never tried Prozac before. M 53 9 months
60 MG
6/16/2012
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 4  GAD, panic disorder, depression Nausea, jitters, rapid heart rate, wired feeling, unable to achieve orgasm, constipation, headache, dry mouth, dizziness and loss of appetite. Hi I just started cymbalta 6 days ago. I had nausea, and all of the above symptoms when first starting, but most of them already went away. I still have dry mouth, a little bit of a wired feeling, and the sexual problem, but overall my moods have already gotten so much better, I am less fatigued, and my anxiety levels have decreased. From here, I am hoping that things will just get better. I tried many antideppressants in the past, and they all made me very tired. This med I can take in the morning or early afternoon, without any kind of fatigue. This med can cause some sleep disturbance so I recommend taking it no later than noon, and it shouldn't affect your sleep. I take 1 mg of Klonopin before bed, and I have been sleeping great without waking up in the middle of the night. If you take this med with food, you won't feel as nauseus either. For me, the nausea already went away. I am very optimistic about this drug, as I noticed a difference just after one dose. F 36 6 days
30mg 1X day
6/10/2012
 3  spinal stenosis/arthritis sweating, dry mouth, weight gain Cymbalta has helped relieve the pain of my spinal stenosis and back arthritis to the point that I can be more active than I use to be. It has not taken the pain away totally, but sure has helped. I did gain about 7 lbs which is making me feel very uncomfortable,but I'll take the weight than take the extreme pain that I was in. Don't get me wrong, I am still going to get surgery for my back, but this has helped put a "bandaid" on my pain until I get it done. I wouldnt like to be on this for a long period of time. The sweating/hot flashes are pretty bad, get them every day. The only thing that scares me is that I have been reading peoples posts about withdrawals. F 52
60mg 1X day
6/10/2012
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Patient History
 1  Nerve pain Brain zaps, heart palpitations, nausea, loss of appetite, muscle jolts ( whole body), strange vivid dreams, frequent yawning, uneasy sleep, some speech difficulty Don't take it!!! F 42 1 months
30 mg 1X day
6/10/2012
 1  Chronic paun After two months of use, began to experience stroke-like symptoms including loss of words, confusion, double vision, head pain, lack of coordination. It took a few ER visits and MRI's to rule out stroke. This was coupled with sudden onset of narcolepsy. I was falling asleep while talking, eating, DRIVING, and when I did want to sleep I would go for 15 hours. A sleep study found nothing. On the whole doctors could not figure out why these things were happening, failing to notice that the only thing "new" was the two months of Cymbalta I had taken prior to the onset of symptoms. After two more months, I simply stopped taking the Cymbalta and all the side effects went away within a week or two. I notified the company, because I believe these are incredibly dangerous side effects that need to be looked at, although I doubt they will study it. F 38 4 months
60 mg 1X day
6/9/2012
 2  anxiety, depression, muscle pain nausea, vomiting, headache, head buzz , dizziness, weakness, unable to get up. I only took it once that was enough, the worst day and night ever, I have never felt so ill, it took three days for these effects to go away F 27 1 days
30mg
6/8/2012
 5  Severe anxiety attacks I have stomach discomfort with any SSRI or SSNRI meds so my doctor suggested I take a 10 mg Zyrtec daily, along with the Cymbalta, where the antihistamine effect alleviates any upset stomach Cymbalta changed my life -- without it my anxiety attacks come back with a vengeance. If I'm going through an especially stressful time I'll take a daily dose of 60 mg knowing my doctor will approve my going to 90 if needed, otherwise I try to stay at 30 mg. I didn't have any weight fluctuations with it nor sexual side effects. F 50 3 years
30-60 mg 1X day
6/4/2012
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 1  anxiety, spinal nerve pain Stomach pain,nausea, dizziness overall shaky feeling. On day 1, took 30 mg at 9:00 pm. Woke up at 2:30 with stomach pain and vomiting my guts up. This lasted until 6:00. Took Nauzene for nausea all day and didn't help. finally at 5:00 pm managed to drink cup of soup. Worst medicine after only one dose I've ever taken. The bad part is I was too sick to attend my grandson's graduation. F 63 1 days
30 mg 1X day
6/2/2012
 5  Depression, weight control and pain Im a jockey I've had severe falls and a life time of weight problems to stay in racing that has caused me some very deppressing actions and thoughts since I've been these pills I've never been to happy in the mornings to b at track work nor at loosing weight to ride raceday but this is by far the best thing I've ever dealt with at the minute. M 24 1 weeks
30
6/1/2012
 3  Rage/Anger/Inpulse Control Bear in mind that i have been taking Remeron for 11 years, and had to add Cymbalta 2 years ago because I had been experiencing rage/anger (my dr. called it 'impulse control'). It worked for the rage. Get occasional dry mouth, and have had palpitations for over a year. Also began having difficulty sleeping, but I don't know if it's because of the Cymbalta or not. Hmmmm. My memory has gotten really, really bad. Need a change (from Remeron + Cymbalta), or maybe from my other medications (too many to list). M 53 2 years
30/60 1X day
5/28/2012
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 1  depression and pain Very dry mouth. Had to have water with me if I needed to speak. Dialated pupils. Throwing up. Diarhea. Sweating. Forgetfullness. Migraine. My brother warned me about this when I told him I was prescribed it. But I thought I need to do what the Dr. thought would help. Woke up on day 5 with a Migraine it went to throwing up, and other flu-like symptoms. It is AWFUL. Would agree with my brother, never recommend to anyone. F 45 5 days
30 mg 1X day
5/28/2012
 1  Depression HORRENDOUS nausea-vomiting every 15 mins, unable to keep even water down, shaky, jittery, extremely dilated pupils, headaches, sleeplessness, no appetite...still not well few days after taking it F 29 1 days
60mg
5/25/2012
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 1  depression and anxiety headache did not help my depression or anxiety at all, nor with pain F 30 65 days
30mg 1X day
5/23/2012
 1  Depression, rheumatoid issues Agitation, anxiety and severe anxiety attacks, anger, heart palpitations, extreme dizziness (felt like ocean waves in my brain), horrible nightmares I feel that taking Cymbalta changed me--I still experience heart palpitations and anxiety, even a year after discontinuing the meds F 52 6 months
30mg 1X day
5/22/2012

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