CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Anxiety Depressiom Tingling scalp, NO SEX DRIVE, reduced self control, BRAIN ZAPS The drug certainly eliminated the anxiety which was my primary concern at the time. However, the other side effects severely hurt your quality of life. The brain zaps are no joke if you happen to have this side effect - almost mini-seizures in rapid succession. I stopped cold turkey 5 days ago along with a very aggressive exercise program and office therapy! Wish me luck! M 45 2 years
60 1X day
10/13/2014
 2  Bipolar depression, GAD Am still awaiting an antidepressant effect. Meanwhile have felt more depressed and generally slowed down: anorexia, tiredness, slower talking, slower walking, constipation. Other early side-effects have been headaches, irritable watery eyes (improving), hair loss (persisting), anxiety, akathisia, no motivation (worse), reduced libido. Appearing to friends/family/nurses as flat and looking more depressed. Anorexia is severe. Hoping that I'm through the *2-week wall*! We'll see.. M 56 14 days
60mg 1X day
10/3/2014
 1  depression Horrible. Totally horse tranq knocked out for 12hrs within 2hrs of tasking it couldn't focus on anything laid down and stayed there all day apart from running to the toilet with diarrhoea a few times. Could sleep later without restless legs then slept for another 12hrs. One of the worst meds I've been on. M 49 1 days
60mg
9/27/2014
 1  depression auditory hallucinations!!!! other side effects were minor, but I heard music coming out of the wheel of my car; initially I thought it was very funny, and figured if I know I'm hallucinating I must be OK, but then I started to hear things that I wasn't sure if other people heard. Called the doctor SO FAST to go back on to Cipralex! F 51 4 months
20 1X day
9/25/2014
 5  anxiety I feel awesomely numb while taking Cymbalta. After only a couple of weeks taking the drug my thoughts improved, anxiety stopped completely, and I could hear what people are saying better. I do notice that my memory is not great and that I love sleep! It definitely got rid of what were hypochondriac-like thoughts, and completely. Sleep is amazing on this stuff. However, I'm scaling back from 60mg for 6 years to 30mg because I do notice my memory is affected. F 39 6 years
60 1X day
9/22/2014
 1  depression HIVES-CIRCLES AS BIG AS MY HAND ON MY INNER THIGHS THAT HURT TO THE BONE! F 66 14 days
30 1X day
9/17/2014
 5  depression ,fibro myalgia, syatica A little nausea first couple of days and jitters gone fast. Lived on a heating pad with lower back no motovation depression,fibromyalgia,after two week felt great stayed great for two months then had to get my dose increased from 20 to 40 mg. Never felt better. 63 3 months
20-up 40mg
9/11/2014
 1  chronic lower back and leg pain I had seizure-like symptoms. Shaking uncontrollable. Had to be taking to the hospital and got 3 different meds to stop it and a bag of fluid..bad thing is i cant remember any thing except getting up for work at 4 am till around 3-4 that afternoon..i still experienced some shaking for around 4-5 days afterwards... never again will i take this..now i'm very scared of taking any medicines. .., F 46 1 days
30
9/9/2014
 3  Chronic back pain from injury Begins with nausea for about 2 months but has subsided makes my head feel stupid or delayed have had headaches better now I missed 3 doses when I forgot meds on a trip and I snaped! This stuff is dangerous if you quit cold turkey or miss a few pills! But for the back pain it has really helped! Thinkin I'm getting off this crap soon and see how the pain goes. Definitely not a life long drug, probably fry my brain. I wonder in 10yrs from now they will figure out this stuff fries your brain or other problems. M 42 5 months
60mg
9/5/2014
 5  Depression, fatigue, brain fog None that I noticed If you are having major symptoms, do not be afraid to try this drug. Just ramp down from your old medicine if any and ramp up slowly to this one - take a whole week. This medication has quite literally changed my life. I'm a professional and wasn't able to get out of bed before 8, and then I was foggy through about noon ... not good. I would sleep 12 hours sometimes and still have these issues. I am now sleeping normally, 8 hours or maybe 7 at times. I feel wonderful in the mornings now and can immediately get up and start my day without the fog. I have energy and am enjoying my interests and activities again. I don't know if I'm having loss of appetite or weight loss quite yet, but I will say that previous to taking Cymbalta, I ate to wake up or clear my head and feel better. That's no longer happening and I'm back to riding my bike, gardening and other activities. So I won't be surprised to lose a few pounds due to my decreased need to consume calories and my increased caloric burn. I'm impressed -- in my 15 years of having periodic episodes of depression, I've never had such a drastic turnaround. Give this drug a shot -- if it doesn't work for you, ramp down slowly and move on. Nothing to lose and a lot to gain here. F 43 12 days
60 mg 1X day
9/1/2014
 4  Depression No side effects that I'm aware of. F 58 12 years
60 MG 1X day
8/23/2014
 1  fibro pain I went into anaphylactic shock taking Cymbalta F 60 1 weeks
8/20/2014
 1  pain Sweating, throwing up, stomach pain, can't sleep missed 2 days of work F 59 2 days
8/20/2014
Email
 5  neuropathic pain Biting myself when chewing Numbs the pain just enough so that I can handle it with no problems at all. F 60 3 years
60mg 1X day
8/15/2014
 5  Panic disorder and nerve damage Like with Celexa, I had the usual 2 weeks of side effects. Stomach upset, dizzy, shaking, sweating, insomnia. After the first 2 weeks, which any good Dr. should have warned you about, I'm fantastic:) Celexa and Cymbalta both have a 2 week side effect allotted time, both at the beginning and when you're quitting. Keep in mind that it metabolizes out of your system in 72 hrs. I'm finding most of the reviews are coming from people who were not given a heads up. Should have stuck it out for the 2 weeks. F 30 2 years
60 mg
8/10/2014
Email
 1  Anxiety, body pain from lupus I took this drug for 2 days and I will never take it again. Within hours of taking I started having the worst stomach cramps I've ever had (and I've given birth) then severe nausea and diarrhea. I started to research this drug and it is not a good thing. I would never recommend it. F 23 2 days
30mg
8/4/2014
 2  Depression, panic attacks F 60
30 1X day
8/2/2014
Email

Patient History
 2  Nerve Pain and Depression Hair loss, nightmares, blackouts, irrational thoughts I ended up in the hospital after having a few drinks at a party and blacking out completely. This stuff is dangerous. My hair loss still hasn't come back. F 36 2 years
60 mg 1X day
7/31/2014
 1  depression & general anxiety exhaustion, anorexia tendencies, headache, socially withdrawn, hallucinations if i missed a dose or drank alcohol, sadness. The drug may have helped anxiety a bit but WITHDRAWAL IS SO HARD. please think before taking this drug. It put me in more of a depression then ever before when i tried to come off of it. I had a full blown panic attack for the first time, dark thoughts, headaches, exhaustion,diarrhea, aches. I had been on paxil and celexa previously and never had withdrawal side effects. The benefits by no means outweigh the side effects. I finally was tapered off with the assistance of prozac- hoping prozac will help but my ultimate goal is no meds!! F 21 5 months
60 mg 1X day
7/29/2014
 1  nerve pain Made me unable to think, eliminated my motivation, could not focus, made me very tired, but couldn't sleep, them towards the end became out of sorts and felt angry for no particular reason, did NOT take care of pain!!! When Dr. took me off it, I had withdrawals like hard drugs and ended up in kidney shut down and had to go to emergency. This drug is dangerous! It made my life a disaster. Should NOT be approved for pain issues, it destroys your life! Shame of FDA and any Dr. that prescribes it for pain. M 58 9 weeks
30 mg 2X day
7/26/2014

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