CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Depression Terrible constipation and have headache on and off but in last week everyday and today a bad frontal headache where I can't bend forward. I feel it has helped a few ms symptoms such as the electric shocks, also I'm not sure how effective it is being with my depression I think I'm on an even keel but do still feel uninterested in things etc. F 44 5 days
60mg 1X day
5/9/2021
 1  Pain, disc degeneration etc Shaky and jerky, horrible stomach pain (like a hole was burning through it) and nausea for days, headache with burning sensation in front of my brain, face and hands turned red with burning sensations on top of hands and feet, etc I was first tried on gabapentin with “catastrophic results”- looked like I had Parkinson’s and ended up in ER three times, shaking so violently, once felt like something popped in my neck and was burning down my neck, could barely walk and talk. After taking only ONE cymbalta this started again, along with horrible stomach pain and nausea for days, like a hangover on steroids. Felt like I’d been poisoned. I don’t know why my body reacted so horribly to these meds, but the worst part is the doctor’s attitudes towards me - I cry in pain more days than not, can’t work since these meds as pain is worse, and I’m scared feeling my docs are going to kill me with meds! F 50 1 days
30
5/8/2021
Email
 1  Depression Anxiety Headache nausea diarrhea frequent urinating shaky feels like a had 20 Red Bull's pupils are so dilated feels like eye bulging out of my head restless legs no sleep your sleeping but awake. Horrible never again F 40 1 days
1 1X day
4/19/2021
 1  Anxiety, Fibromyalgia Increased anxiety, constipation, scary brain fog, drugged feeling, grinding teeth all day, very tired, no motivation. Was not warned about the difficulty in discontinuation. Terrible to withdrawal from! F 58 8 weeks
90 mg 1X day
4/19/2021
 1  Fibromyalgia pain and Insomnia Dry mouth, drowsiness,feeling tired all the time, difficulty sleeping, anxiety, jittery, headache F 55 10 days
30 MG
4/18/2021
Email
 4  Anxiety/autism Increased sex drive, headache/tiredness, loss of appetite, weight loss At first this med decreased my ability to climax but after several weeks I regained the ability and experienced increased sexual desire, very surprisingly. I do experience some flu-like symptoms occasionally (almost like a fever, although I don't have a fever). F 20 40 days
30 mg 1X day
4/7/2021
 1  Fibromyalgia Felt like I was dying! Worse than flu like symptoms...severe migraines...vomiting..fatigue...palpitations...never take this...ever! F 45 14 days
20mg 1X day
3/25/2021
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 1  Depression, anxiety Alcohol, cigarette craving. No libido delayed ejaculation total anhedonia, numbness everywhere and agression. I lost weight on it. I was mean emotionless robot and changed it to wellbutrin... my life is perfect again! 27 2 years
90 1X day
2/28/2021
 3  Pain relief Depression, feelings of hopelessness dark thoughts. Had to stop though may revisit therapy. At lower dosage Worked wonders for neuropathy and generalized joint pain even significantly reduced many of my neurological symptoms M 60 3 months
30-60 mg
2/17/2021
 3  MDD Brain fog Tiredness Insomnia Reduced appetite First month: full of energy, stop of suicidal ideation, happier episodes, motivated. Progressedto some episodes of insomnia even though exhausted. When sleeping experience, it was heavy REM with bizarre dreams, meaning not fully rested. Felt lethargic. Do feel 60mg is too high, therefore will reduce to 30mg as feel MDD wise, its helped significantly in comparison to SRRIs alone. Any withdrawal I have noted is similar to that of withdrawing from any SRRIs, indicating its the serotonin element of the drug that produces the significant side effects. Overall, I feel this is effective with the appropriate dose and management as need a drug for long term use for MDD. F 31 2 months
60mg 1X day
2/13/2021
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 1  Fibromyalgia/Depression Pain, diarrhea, panic, insomnia I have only taken one pill, took last night at 6pm. I have been up all night with terrible stomach pains and diarrhea. I feel so jittery and nervous like I drank a bunch of energy drinks. Heart racing, sweating. I have been unable to sleep all night and the pain I feel is so much worse. I am not taking this again. F 31 1 days
30 mg 1X day
2/13/2021
 1  Back pain This drug should be taken off the market. I have suffered from extreme dehydration. I had to go to the ER. Extreme diarrhea for five hours at a time. My skin felt electric. Blood in diarrhea. I'm weaning off after four weeks and it's a living hell. I feel like the weaning is going to be impossible. Migraines. Shaking and shivering. My doctor never mentioned this to me. Pharmacist never mentioned this. I have quit my job because I cannot work. Everything is aching. I've been in bed for two days. Do NOT take this medicine. Read about the life long side effects. F 48 12 days
60 1X day
2/10/2021
 1  Pain This will cause hell in your life. I had a immune disease and on other medications. The side effects are from the drug not the disease as I was lead to believe. Do not put this dangerousness drug in your body. Life will deteriorate and health put in danger. Don't take this drug. Please don't take this drug. F 63 5 years
60 2X day
1/31/2021
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 1  Pain Fatigue, Weakness, Dizziness, Nausea, No energy, Muscle Pain, Joint pain, Memory loss, Loss of motivation, Loss of interest in people and the things I used to love doing, Loss of concentration, Stomach pain, Alcohol cravings and Chocolate cravings, No longer able to have a climax, Teeth breaking, cavities, and discolouration, Hearing loss, Blurry vision, Weight gain, Bloating, Hair loss, Dry hair, Leg jerks, High blood pressure, High cholesterol, High liver enzymes, Urinating problems (couldn’t urinate or empty bladder) I had no life while taking Cymbalta. I was only existing. It took me 2 1/2 years to taper off Cymbalta and it was very hard. I lost over 10 years of my life to Cymbalta. I’ve been off for 1 year and I have a life again. Every side effect is gone, even the pain. I will never take another medication like Cymbalta again and I will never advise anyone to take it. It not only didn’t help with the pain I had, it caused me to have more pain. F 61 10 years
60 mg
1/25/2021
Email
 1  Stress and fibromyalgia Increased blood pressure, tinnitus, neuropathy, lack of feeling/emotion, dark circles under eyes, insomnia, headaches, dizziness, nausea, vision problems, etc., etc. This drug has taken away my joy and taken away years of my life. Doctors will tell you to either stop cold turkey or take every other day then stop. This is dangerous as it has a 12 hour half life. The side effects are horrendous if you try to taper too quickly. Thankfully I found a FB group that advises how to properly and slowly taper. I so wish I had NEVER started taking this poison! There are over 200 known side effects. F 57 11 years
30
1/25/2021
Email
 1  Anxiety Decreased libido, suicidal ideation, doctors are not informed or trained on how to taper a patient off the drug, if I was late or missed a dose extreme side effects-confusion and difficultly comprehending Don't start it. Doctors who prescribe it and pharmaceutical companies have never been informed how to ween patients off this drug and the long term side effects are endless. This is poison. F 35 4 years
120 mg 1X day
1/19/2021
Email
 1  Fibromyalgia Projectile vomiting, horrible diarrhea and burning, throbbing headache in temples with one dose. One dose is enough to know not to take a second dose. No thanks! F 56 1 days
30 mg 1X day
1/14/2021
 5  Chronic pain fatigue Warm feeling and yawning without being tired..stomach gurgling I was happily surprised within 3 hours of the first dose my pain had greatly improved. So far I was able to fall asleep in under an hour. No grogginess or feelings of no rest these last 3 days! My mood seems even better also. Decreased appetite is a plus as well. F 33 3 days
60mg day 1X day
1/11/2021
Email
 1  Anxiety, depression, panic attacks Headache, nausea, anger, restless F 61 1 days
30MG 1X day
1/11/2021
 1  Pain Awful to wean off of, terrible side effects headache, nausea, craving for something to eat, or another pill to alleviate the symptoms. So glad I'm off of it, yet it took two month's to feel better. It did work for nerve pain but the side effects are not worth it... M 50 2 months
20 1X day
12/24/2020

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