CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  major chronic depression/suicidal I feel the best I have felt in years. I have been on anti-depressants since 1986. I have been on this since Jan of this year and to my knowledge have no side effects. I think more clearly, sleep well, and am more alert and generally am accomplishing more than I have in several years. F 60 3 months
4/3/2007
 1  Anxiety Dry mouth, nausea, vomiting, dizzy, disoriented, "Zombie" feeling. Blurry vision. I felt like I was having a panic attack. all from 1 dose! I can't believe this drug is on the shelf and can be given out so freely. The doctor put me on a 30mlg dose with the idea of increasing me to 60mlg. If this is a cure I will suffer with anxiety! F 27 1 days
4/3/2007
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 3  BiBolar II Depression None - Maybe more Tired Rate it at a 3 M 64 180 days
4/1/2007
 1  Social Anxiety/Depression First few weeks: trouble sleeping, dizziness, nausea, acne Entire time: tremors in arms and head, A LOT of sweating during sleep, mild nausea, difficulty concentrating Withdrawal: Very dizzy/lightheaded, nausea, drowsiness, more sweating, clouded thinking, crying I was up 120mg daily the last 2 months. The side effects were unpleasant and it did not seem to help ease the anxiety/depression much at all. I felt like I had to cry much of the time but unable to. After I stopped the meds crying came very easily. M 23 4 months
4/1/2007
 3  bi-polar with body aches While on it: at 30 mg it was not effective for all over body pain. At 60 mg it resulted in loss of appetite, loss of desire for my husband, difficulty waking up and staying awake throuhout the day, and although my pain management was undercontrol I did not feel like "myself" in my head anymore. Withdrawl was a NIGHTMARE ... really intense for 2 weeks with extreme mood swings and aggitation, nausea, vomiting, and by week 3 pain returning. This drug should be taken off the market. Read packaging info and FDA reports on potential liver damage. F 30 4 months
3/31/2007
 4  Depression and Anxiety Dry mouth first couple of days. Maybe slight headache occasionally. I don't know about any sexual side effects yet. I have not gained weight yet either. The first couple of days I didn't want to eat much but my appetite has returned. I already had menopausal hot flashes and night sweats so I don't know if they are related to this drug or not, but I'm used to them. I took Prozac in the mid 90s and it worked fine, I went off it after a year and only recently got so depressed and anxious again to the point where I felt i needed help. I've only been taking it for a week and just increased to 60mg. I felt better the first day and it's really helped me. I feel good and my anxiety is much less. I can focus better on tasks and am not as distracted or worried about things. So far so good. F 53 2 weeks
3/30/2007
 1  Depression, Anxiety Withdrawl-MAJOR flu, profuse swetting, brain and body zaps, total confusion, body pain, extreeme mood swings, bouts of uncontrollable crying, dizziness, weight gain, impaired speech, impaired motor skills, unable to put my thoughts together, upset stomach, jaw and tongue tightness, nightmares, night sweets, joint pain, headaches, swelling/puffiness cymbalta has MAJOR withdrawl symptoms not disclosed by lily or the doctors prescribing it. It did seem to help somewhat with the depression, but the withdrawl from stopping is far worse than the benefits it brings, go with a different medication, and not effexor, it is the same way. F 31 4 days
3/30/2007
 1  mild depression suicidal thought, loss of appetite, sleeplessness, agitation,anger it needs to be taken off the market. My 24 year old neice committed suicide while taking Cymbalta. Im planning on sueing the company for directly causing her death. Many people have committed suicide while on his horrible drug. Alot of families of victims have filed a Class Action Lawsuit against Eli-Lilly for their incompetence. Justice for the many victims of this death drug. F 24 2 weeks
3/29/2007
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 1  depression Major sweating at night. Had to change my clothes about five times a night. Very sedating and I was in a brain fog most of the time. Too spaced out to be depressed. It took me days just to get simple things done. I am now getting off this useless (for me) drug. In weaning myself off it, my brain is doing the weirdest things. I feel dizzy a lot, and I have this sort of white noise noise in my brain much of the time. It's been almost a week since I stopped and I can't wait until this drug has left my system. I can see now how zoned out I was and I'm looking forward to just being me again, without any drugs. The only drug that ever worked for me was Prozac, but that stopped working after about five years. F 41 5 months
3/29/2007
 1  mild depression suicidal thought, loss of appetite, sleeplessness, agitation,anger it needs to be taken off the market. F 24 2 weeks
3/29/2007
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 1  anxiety I had an immediate and severe reaction to this drug. I had hot flashes, I felt disoriented, ended up having a serious panic attack and had to go to the hospital. I have read that this is a common reaction to Cymbalta with a first dose. My (old) doctor thought that it was because the dose was too high for a first go at it and tried to talk me into taking it in microdoses until I adapted to it. Given that my experience was extreme and frightning, I told her she was kidding herself! M 38 1 days
3/29/2007
 1  mild depression suicidal thought, loss of appetite, sleeplessness, agitation,anger it needs to be taken off the market. F 24 2 weeks
3/29/2007
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 1  mild depression suicidal thought, loss of appetite, sleeplessness, agitation,anger it needs to be taken off the market. F 24 2 weeks
3/29/2007
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 3  Depression, Fibromyalgia Extreme night sweats, hot flashes, weight gain (craved sugar), no libido, no orgasm. It helped initially with depression, initialy I had an increased sex drive and it helped with the pain of Fibro. That did not last! Pain came back, sex drive died, depression came back, and the side effects got worse. I went from Lexapro which did not work to Cymbalta, which worked initially then stopped. I have gained 60 pounds from both meds, I have no ability to orgasm or desire to have sex. I tried to stop it before and had horrible withdrawel: dizziness, headaches, vertigo, etc. I went back on and started having very vivid dreams, hot flashes, and drenching night sweats. I have come off again with help of Wellbutrin, I hope it works, withdrawel is awful. F 29 8 months
3/28/2007
 3  Depression, anxiety sleeplessness, trouble achieving orgasm, lack of appetite (to the point of being a problem), blurred/strange vision, I didn't have side effects when I took a lower dose of cymbalta, but once I switched to 60 mgs -- and stopped taking remeron, my old drug-- all the awful side effects started. I would wake up every night (literally. Even when I attempted taking some sort of sleep medication to help) at around 6 or 7 30, then not be able to fall back asleep for a good hour and a half to two hours. It was incredibly irritating and caused a lot of exhaustion on my part. I also noticed a pretty major decrease in my appetite-- this paired with my use of (prescribed) adderal meant I wasn't eating EVER-- had trouble achieving orgasm during intercourse (it took forever, absolutely forever), and towards the end, even had spots in my vision/blurred vision. The worst was that I loved how this drug made me feel mentally-- I really did-- but I just couldn't stand the physical side effects. I gave it a 3 for this reason; of course, these side effects by no means pop up in every patient, and if they don't in yo F 19 2 months
3/27/2007
 1  Fibromyalgia Headache, extreme fatigue, nausea, sweating, slurred speech, halluinations, insomnia, depression, sexual side effects, terrible anxiety. Taking this drug was the woarst thing I have ever experienced. I felt as if I had been poisoned and it did not help with any of my pain. It took me days to recover after I stopped taking it. F 36 7 days
3/26/2007
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 1  depression/anxiety/pmdd Could not sleep, so anxious I felt I was crawling under my skin. Some chest pain, decreased appetitie. A nervous wreck I only took it for one day and I had to stop. I was previously on effexor for PMDD, but I started to get panic attacks that I thought were related to the effexor. I am currently still trying to find a more "mild" drug to help with my pmdd/anxiety, no luck as of yet F 27 1 days
3/25/2007
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 1  Treatment Resistnt Major Depression Did nothing for me. Absolutely Nothing. Have tried all of the SSRI's and SNRI's to no effect. Been depressed for 4 years. The only thing that has helped is a recent switch to a tricyclic antidepressant imipramine. M 49 120 days
3/24/2007
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 4  Depression no firm erections, difficulty ejaculating, intense orgasms (nice!), dizziness, night sweats is better than Lexapro - which I was on for 2 years (20 mg.) M 60 5 months
3/23/2007
 5  major depression sweating the only thing that gets really irritating is the hot flushes, guess they'll keep me warm in winter though! F 43 8 months
3/22/2007

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