CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Fibromyalgia & Depression When I stated on 30mg just had a few episodes of diareha, some dry mouth and slight headache, this was only on the first week. Then upped the dose to 60mg and have been on 60 mg for a week now and feel great. So far this medicine is the greatest thing in the world for me! I have suffered from so much pain everyday for years and have become so depressed from living a life of pain, now I am reborn again, no pain and very happy. I have cryed but not from pain or depression but from happiness. I felt that my life was never going to be pain free until now. I hope this continues and I don't develope any unbearable side affects becouse I can't go back to the painful and depressing life I had to live. F 48 15 days
5/27/2009
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 1  Neuropathy - Degenerative Joint Dis Brain Zaps like a short circuit in my brain - Lithargic - Weight Gain- Incredible Anxiety - No energy - Apathy combined with fits of rage and anger - Insatiable appetite for sugar, lots of soda and chocolate -things I never ate before taking this drug - Severe Depression and an overwhelming sense of helplessness I decided to stop taking this medicine completely a week ago today. I was on 60mg and at one time twice a day. At first I got a lot of these crazy short cirucits in my brain but they've almost gone away now. I can't begin to tell you how much better I feel now. Super increased energy, more positive thoughts, sleep better and able to deal with and think a lot better like I could before taking this nasty medicine. I wasn't taking this as an anti[-depressant but a pain management aid. God help anyone that takes this medication for depression. You'll probably want to go out and kill yourself afterwards and put yourself out of your misery. I had many thoughts of suicide and helplessness and being overwhelmed on this durg and thoughts I never had before taking it. I stopped exercising and socializing and became a hermit as I felt more and more paranoid. Again things I never had previously. Best advice - Don't read all this garbage about the terrible side effects of withdraw from stopping Cymbalta. Just do it and get off the stuff and see if your side effects match those of others after you have the meds out of your body for at least a week. I can tell you in one short week I got my life back again and have the high levels of physical and mental energy I had before taking this drug. I'm relaxed and able to function like the person I had always been. Do you know our enitre waste water and now fresh water systems are so laced with anti-depressants today that many aren't safe to d M 57 2.5 years
5/27/2009
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 5  anxiety, depression loss of appetite, nausea - but they went away after a few weeks Cymbalta has improved my life in so many ways...I used to be an emotional wreck at work but now...I can handle massive amounts of stress. I LOVE it! F 27 3 months
5/26/2009
 1  Major Depressive Disorder Perfect while on it long term, problems came when I had to stop taking it. Muscle spasms, brain zaps, irritable beyond words, nauseated, headaches. This drug works great while your on it, though it takes a week or so for your body to adjust. But DO NOT ever stop taking it lol. The withdrawals are terrible. Worse then withdrawing from narotics like methamphetamines. M 32 2 years
5/24/2009
 3  
5/22/2009
 1  fibromyalgia I had horrific dreams. I have hit such a dark place in my head and it is work trying to keep daily life a coexistance with this other person that I feel like moved into my body without permission. I took this med for 6 weeks and weaned off slowly by recomendation of my gynocologist due to my complaints thinking since I am also in perimenopause. She put the time span together and said I should never been given this drug. I was ready to check into psyc ward and I thank Jesus she called me and talked me through. Crying uncontrolably for days and nights on end and I have been off this crap for about two weeks. I am really scared to go to bed. Last night I woke my husband that there was a snake that had bitten my Beagle and it was under the bed. My son works at 5am and said I came in at 4am and asked how he liked his salad, and then went back to bed. My husband asked me why I had different clothes on in the morning than what I had worn to bed. I began to wet the bed. I am trying to stay up. I don't remember when I last bathed and don't care. I am having a lot of physical pain. I confided some things to my pastor's wife for prayer support. If you have faith in Christ just keep trying to get center. Mentally this becomes a war that you have no strength to fight. I am going through this as I write. We need to all get together and form a class in action and file suit against the makers of this death drug. F 45 6 weeks
5/21/2009
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 1  Fibromyalgia severe nausea when not taken with food, over active bladder Was prescribed this drug to help combat the chronic pain of fibromyalgia. Took a very low dose once a day. Had to take with food or I was sidelined with an hour-long bout of nausea. Did not notice a reduction in the Fibromyalgia pain at all. Then starting having to urinate more frequently and experienced incomplete emptying of bladder. These symptons continued to get worse even after I stopped the medication. I didn't make the connection to cymbalta until my OBGYN told me that it had originally been developed as a drug for incontinence! After almost a year of taking detrol to reverse the effects of the cymbalta, my bladder is virtually back to normal. F 27 4 months
5/21/2009
 1  anxiety and pain from stress blurred vision, very tired, couldnt function, moving in slow motion, brain not keeping up with things, my eyes moved very slowly, reaction time slow, dry mouth, chapped lips, interrupted sleep patterns, restless leg!!!! HORRIBLE HEADACHE for 2 days...it felt like worms crawling around in my brain the whole top of my head hurt like I have never felt before! feeling trapped inside my body. I took 30 mg and yea it stopped my pain which was awesome! BUT the side effects scared me to death! I felt like a zombie. I couldnt function at work and was slurring my words. I didn't want to speak to anyone and never smiled anymore. The last few days seem like a blurr. I don't really remember much. I won't take the recommended 60 mg. I took my last pill night before last and OMG! I had rapid heart beat, couldnt breath but I kept telling myself it was all in my mind and eventually it went away. I slept all night but my pain is back. I think I would rather deal with the pain. I won't take this again! F 41 6 days
5/20/2009
 3  Depression Lack of Energy, Sometimes I get anti-social and moody and tired all day It has caused my depression to get to a tolerable level, where most of the time I am not depressed anymore, but I don't know if its the Cymbalta or it mixed with my other medications (Methadone, Roxicodone for Severe Chronic Pain, Klonopin Wafer 2 mg for Anxiety and Inderal ER 60 & Lyrica 150mg for essential tremor and nerve pain), but since I added it to these other medications I have not had any energy at all and I feel like I am asleep all day and just want to lay in bed M 26 29 days
5/19/2009
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 2  Chronic back pain & depression Just took first dose last night. Woke up several times with arm tremors, I feel very anxious this morning and my hands and feet are sweating. Also I have lightheadness, pinpoint pupils this am along with nausea until I ate breakfast. Will these side effects get better? F 51 1 days
5/16/2009
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 1  anxiety and depression short term memory problems, anxiety, exhaustion, dizzy, brain fog, brain zaps, eyes trying to catch up with my head. I never felt right on this medicine. Brain fog, dizzy, more anxiety, short term memory gone, exhaustion all the time. I tried to discontinue this drug three different times, and had to go back on it because the withdrawals were so bad. At my last attempt it took me over six weeks of withdrawaling it was a nightmare. Dizzy, exhaustion, crying spells, anger, flu like symptoms, nausea, vommiting, major brain zaps, short term memory gone, joint pain, poor sleep, I felt like I was loosing my mind, felt like someone was smothering my brain. Please be careful when trying to discontinue this drug, do your research and wean very very slowly. The only warning about side effects from this drug is if you stop it abruptly. They are not side effects they are WITHDRAWAL EFFECTS. Your body is going through a major withdrawal. Side effects are mild when you take a new drug, and can be bothersome at times, and may even go away. WTHDRAWAL EFFECTS, are a nightmare, and are 100x's worst. F 44 19 months
5/16/2009
 1  Depression, anxiety Started perfect, then didn't care about anyone, or anything. didn't care about the future. didn't care when a really good friend of mine died. Started not to care about living. not a depressed feeling, but there was no good or bad in life. a zombie. kinda like drugged people you see on movies of psych wards. Started out doing exactly what i wanted from it: helping the depression, and completely getting rid of the anxieties i was having. I've taken several different antidepressants and none had worked so good so fast. i took 60 mg every morning with my adderall. Over time, i just stopped caring about anything. stopped going to class. stopped going to work. stopped working out(i ran triathlons the previous semester). stopped leaving my apartment unless absolutely necessary (pretty much just to buy food). I eventually didn't want to play World of Warcraft anymore(most addictive drug ever). I got to the point where i was barely getting out of my bed. I was a Cymbalta zombie. M 21 6 months
5/15/2009
 3  Fibromyalgia blurred vision,zombie feeling,sleepy, dry mouth, nightmares I have only been taking this for a short amount of time, but I don't know if I can handle the side effects. I am a mom of 3 small children and feel like I can't take care of them due to the fact I can't concentrate on anything. I constantly space out on nothing and get confused. I have also had vivid nightmares every night. F 25 3 days
5/14/2009
 2  depression and anxiety EXTREME FATIGUE - like moving my limbs through tar, sleep disturbance (no REM stage sleep) and constant napping, muscle twitching and restless legs symptoms at night, weight gain, lowered sex drive WITHDRAWAL IS HORRIBLE. I reduced from 60mg to 30mg under doctor's advice in order to get an accurate sleep study. Within a week I became completely non-functional. Fatigue symptoms multiplied exponentially, I was dizzy, I couldn't concentrate on anything at all (couldn't cook, clean or drive). Doctor prescribed 60mg Prozac to offset effects of withdrawal on day 6 of the Cymbalta dose reduction, at which point I became totally despondent. Withdrawal effects led to reemergence of major depressive/anxiety symptoms: uncontrollably crying, physical sensations of agitation, and suicidal thoughts. Totally unbearable. I went back up to 60mg and cancelled the sleep study because I'm afraid to go off this drug. F 32 1 years
5/13/2009
 1  Major Depression Tremors, anxiety, unable to think, a "disconnected" feeling, ringing in my ears, dry mouth, blurred vision, lightheadedness, lethargic, fatigue Taking this medication was a terrifying experience for me. I was only taking the lower dose (30 mg) and I honestly thought I was going insane. I went to visit my mother on the 5th day of taking it and she almost called an ambulance for me as my tremors were so bad and I was unable to communicate effectively. She thought I was having a seizure. I was either so tired I had to sleep or so manic I thought I was going to crawl out of my skin. I have no history of mania so it was scary. I ended up having what is called Serotonin Toxicity which is a potential fatal problem when serotonin build up in your central nervous system. Be aware that this medication is different for everyone but it was NOT the drug for me. F 30 7 days
5/13/2009
 4  depression Intense cramps in the abdominal aera. Basically in the stomach area and last between 10 to 20 minutus> The pain is so intense that I had to be taken to the hospital. F 54 1 months
5/12/2009
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 1  General Anxiety Disorder Cymbalta works good for GAD, but when the day comes to stop taking it, well, that's another story!!! Been weaning off for two weeks and have been completely off since April 25th. The withdrawl effects of this drug has been the worst thing I have ever experienced in my life. I could do nothing but lay completely still in bed for a week. The withdrawl effects have been brain zaps, diarrea, blurred vision, headaches, and terrible nausea! The drug works, but you will regret ever taking it, when the day comes that you have to stop! Please think long and hard before going on this drug. F 48 5 years
5/12/2009
 2  depression, anxiety, panic attacks nausea constipation hypersensitivity My doctor started me on this drug at a 60mg dose. Over time it was increased to 90mg. I was recently told that 90mg was not recommended even for adults and that it was strange to see such a high dosage. I was told this by a different doctor who I visited after being out of school for a week and a half due to strange symptoms. M 15 10 months
5/11/2009
 4  anxiety, panic, major depression nausea, cotton mouth, and lack of appetite Tried paxil, celexa, buspar, and depakote. Cymbalta works better than anything I have tried. I have been on Cymbalta for 2 days and I can all ready feel the positive effects. F 37 2 days
5/9/2009
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 1  Depression/Fibro Anger, anger, and more anger. Turned me into a raving lunatic! Lilly's going to be in trouble for this one - it should be yanked off the shelf. I am normally so calm, people ask if I have a pulse. But I felt like bashing my fist through dry wall on this stuff. Try Cytomel - it works! M 5 days
5/9/2009

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