CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Fibromyalgoia very flat, non-emotional, numb to everything. Became depressed, hated life. Could not concentrate, loss of short-term memory. I was started on 60 mg Cymbata when I was diagnosed with Fibro. Was increased to 90 mg after pain became very difficult. Pain continued even while taking it but also something else began. I have never ever suffered with depression until I started taking Cymbalta. In the beginning I thought I was depressed due to the pain I was in but after I also had difficulty remembering simple things I knew it was not normal for me. I began to feel numb to everything even things I use to love doing. Had no drive no zest for life anymore. I would not recommend this medication to anyone. If I had not stopped taking it, I truly believe I would have committed sucide. F 52 8 months
90 1X day
1/20/2012
 1  Fibromyalgia I was losing my mind. I did things like letting my dog off her leash in a busy commercial parking lot. I had very vivid dreams but they didn't bother me too much. It worked wonders for my Fibro pain. I just wish it didn't affect my brain as it does. Getting off of it was sheer HELL. I ended up having to count beads in order to wean myself off of it. It took several months and then I was OK. To anyone taking Cymbalta: DO NOT stop taking it cold turkey. You really do need to wean yourself off of it. F 59 3 months
30 MG 1X day
1/20/2012
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 1  Anxiety Horrible experience. Extremely fatigue, bad headaches, vivid dreams, loss of appetite, severe chills and I was freezing all the time. It got worse every week. I taste the medicine constantly which added to my concern, like poison coursing through my veins. Constantly tasting the medicine provided irritation at the roof of my mouth which manifest into a very painful open sore. I could not believe it! This has never happened. Told doctor I will not take another pill. Dr said I put my body under a lot of stress. I've had lots of stressful experiences, I blame the medicine. I've taken Lexapro and I loved it, but reduced sexual desire wasn't good for my marriage, so Dr. suggested this poison. FDA is bought and sold allowing a Toxic medicine like this on the market! Be warned! F 45 3 weeks
60MG 1X day
1/19/2012
 1  Back pain I was told to take for pain and that I needed to give it time to work. I took one pill and went to sleep. I woke up an hour or so later with a horrible headache, cold chill and dizzy. 24 hours later and I still don't feel right. I had dreams about dead people and while I was awake I wondered how my body would fit into a coffin and it was very scary. My pupils were huge and eyes very sensitive. I'm not really into helping others but I can't go on without even trying to warn others. Please don't take this drug, its evil. F 29 1 days
20mg
1/15/2012
 5  Crushed hips, back pain,depression At first i yawned constantly and had dry mouth but over time it stopped, and weight loss love love love this medicine its made a tremendous difference in my life it doesnt really do anything for my pain but helps alot for my depression and moods. F 28 2 years
90MG 1X day
1/14/2012
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 2  Anxiety and depression headaches, numbness in face. F 26 4 months
60mg 1X day
1/13/2012
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 1  Fibro ringing in my ears, brains zaps (I also describe these as slinks in my head) dry mouth, weight gain and excessive sweating. I did not have any side effects for the first two months and the drug does help my pain but I cannot handle the side effects any more. How do you get off this drug?????? do not take this medication it should not be on the market. I would like to see the clinical trials for this med. F 64 8 months
60 mg 1X day
1/12/2012
 5  Anxiety None. Just went from 30mg to 60mg one time daily. This has really helped with my anxiety and racing thoughts. M 38 2 months
60
1/10/2012
 5  depression & pain First few days it was hard to get to sleep and I yawned quite a bit. I have taken Cymbalta in the past and it was helpful to me before. I've noticed that it is extremely helpful with anxiety and obsessive-compulsive issues too. My family has noticed a big difference in me which is always a plus :) F 47 3 weeks
30 mg 1X day
1/5/2012
 3  Anxiety Some sleep disturbance the first week, weight loss I was surprised that there were so few side effects with this medication (I reacted horribly to Effexor). I am not sure I am getting much relief from the anxiety but I am going to keep trying for a few more months. An added benefit has been that it seems to have increased my metabolism. I have lost weight but maintained by normal appetite M 35 3 months
60mg 1X day
1/3/2012
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 1  depression/anxiety brain zaps, increased suicidal thoughts, weight gain, mood swings, insomnia, no self worth or motivation at all. cymbalta was the worst thing to ever happen to me. i started taking for severe depression and at first it seemed to help. for about 6 months i took 20 mgs twice a day. then it seemed to not have near the effect it did before and i attempted to kill myself. my mom thought maybe a higher dose was needed. so i went to 30 mgs twice a day. Depression symptoms improved but i was tired constantly and had started to gain weight. this started a cycle of upping my dose every six months until i was at the highest recommended dosage of 120 mgs a day. For about a year i stayed at this amount and felt increasingly awful as time past. suicidal tendencies becoming overwhelming, brain zaps even if i missed just one pill. i lost my parents insurance and cymbalta was 250 dollars a month. i was buying 6 pills at a time for 35 dollars and only taking half my dosage and suffering the awful withdrawals. finally a solution came. i had gained 80 pounds over the 4 years i was on cymbalta and i went to a doctors weight loss clinic. the doctor told me if i wanted to take phentermine, i had to quit cymbalta because it was like taking a double dose. so she prescribed me 60 mgs of prozac and 37.5 mgs of phentermine daily. SHE ALSO SAID STOP TAKING CYMBALTA COLD TURKEY THE NEXT DAY. i was scared to try, but i did it, and it worked. mild withdrawals for about a week and now i have been off of it for almost two months. i feel better than i ever have. F 22 4 years
60 MG 2X day
1/3/2012
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 1  Fibromyalgia and depression Drowsy. Headaches. Dizzy. Nausea. Extreme depression. I was first given this drug for fibromyalgia and it did nothing for the pain. I may as well been given a tic tac. I gave it a good honest try for 2 months, but it made me suicidal and the pain persisted. I never had any luck with any serotonin drugs, but did fine when switched to Gabapentin. F 45 3 months
60MG 1X day
1/1/2012
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 4  Severe back and leg pain This is the second time on the drug and I knew what I was getting in for but desperate for the pain relief it gives. Side effects: clammy, sweaty skin, jaw clenching, frequent yawning, fatigue, hair loss, decreased appetite. The pain went away or diminished greatly after starting on 60 mg after a week on 30. It is VERY hard to come off, and it took me 5 months of taking out a few sprinkles at a time, vertigo almost too much to bear......tough to find a drug that relieves the pain but so many side effects and nightmare to come off. I have to say that for the pain relief I am very happy, so do not be afraid to go on it for that.....go off slowly, is all. F 56 2 weeks
60 mg 1X day
12/31/2011
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 1  Anxiety None while on it, except it did nothing for me. Cymbalta withdrawal is a different story: Paresthesis (zapping sensation in brain) Tinnitus Nausea Dizziness / vertigo I have NEVER had these symptoms before in my life. This product is dangerous. M 37 2 months
30 then 60
12/29/2011
 5  back and nerve pain diarrhea and weight loss has helped m greatly M 43 3 months
30 mg 1X day
12/27/2011
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 5  depression Occasional headache some sexual loss helped my backpain and nerve damage in my feet even though prescribed for depression helps that too F 40 1 years
30mgs
12/24/2011
 4  BPD, Depression, Anxiety F 23 6 months
60 1X day
12/21/2011
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Patient History
 1  Anxiety Apathy, heavy alcohol use, delayed climaxes, disregard for others, carelessness. Dangerous. Almost cost me my family, marriage, house, job - everything I'd worked for. M 49 12 months
30 1X day
12/21/2011
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 5  Depression Give it a good try; use Tums or omeprazole for stomach side effects; don't miss a dose; I found taking it at noon works best for me; keep hydrated; combine with psychotherapy. I have been depressed for decades. I am also a recovering alcoholic/drug addict (clean/sober for five years now). I suffered from major depressive disorder, suicidal ideation and attempts, seasonal affective disorder, generalized anxiety, self mutilation, and dysthimia (sp?).I tried paxil, welbutrin, lexepro, and celexa. Cymbalta has finally relieved my depression. I have been on Cymbalta for nine months. I am curious to see how I do this winter - depression is usually worse for me in winter months; this will be my first winter on Cymbalta. I attend psychotherapy and also tend to my spiritual health. The horror stories of Cymbalta kept me away from it. Out of desperation I tried it finally; so glad I did! If and when I come off of it, I will treat it as a med that needs progressive withdrawal measures. I recently started taking clonazepam for anxiety. The combination is working well for me. I take 1/2 tab of clonazepam at night I take 60 mg of Cymbalta at noon. I get flu like symptoms (body aches/fatigue) immediately if I skip a dose or am late with a dose. I get occasional stomach upset/burning, which I take Tums and omeprazole to relieve. No other side effects thus far. For me, suicidal ideation was immediately relieved within first couple weeks of taking Cymbalta. (Life is so much easier without those pesky, self loathing, negative thoughts!) Cymbalta also lessens menstrual cramps and lower back pain for me; although, I still take NSAIDS for both occasionally (even F 42 9 months
60 mg 1X day
12/18/2011
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 5  Severe depression none Cymbalta has saved me. I was severely depressed, tried every type of anti depressent on the market, as well as mood stabilizers with anti-depressents. This was the only medication that worked for me. It took a while, and a few uptitrations, but it is my miracle medication. F 37 3 years
120 mg 1X day
12/17/2011

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