CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Depression/Bi Polar EXTREME constipation!!! Initially had dialated pupils - looked like I was on Meth - Quit, reintroduced to my system by gradually increasing dosage - this worked... Other than the constipation... I loved this medicine! I no longer felt like hiding from crowds, was confident enough to express my feelings (calmly too)...However after about 6 months I had to stop taking it - that goes to show you how BAD the constipation was - was even taking presecip laxatives - am on Wellbutrin now and it's not giving me the side effects, but does not help with mood/anxiety NEAR as much - F 40
6/14/2008
 1  depression suicide my wife Sharon Coalson committed suicide by self inflicted gunshot on dec. 12 06 as a result of an adverse reaction between cymbalta and lunesta. She was misdiagnosed for depression when in fact she was experiecing a bipolar state. the abject apathy of her doctors and treatment was criminal. i finally obtained her medical records which gave me an insight into what she was coping with and registered my complaints with the alabama board of medical examiners . she was also prescribed xanax for anxiety --anyone prescribed three medications all with the potential side effects of suicide and mis diagnosed does not stand a chance. i can give more in depth discussion personally by tel 256 236 3082 or [email protected] or "tony coalson" in google and read the article regarding her suicide. medications such as these without close supervision, awareness, and monitoring are deadly. F 62 6 months
6/13/2008
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 2  Fibromyalgia, Depression Terrible stomach pain, severe diarrhea, dry mouth, nausea Awful! It made me sick and made it hard to concentrate or think. I felt blahh! F 34 3 days
6/12/2008
 1  depression pain After first dose, nausea set in and then an overall sick feeling, very very bad heartburn, anxiety, tightness in chest I do not like most medicines and try to avoid them but my doctors keep telling me I need them. I had two doctors warn me about Cymbalta but my main doc wanted me to try anyway. I will not take it again even though I usually try things for a week; this day has not warranted another dose! When you are sick, the last thing you need is a pill making a good day turn into a nightmare. So sorry for anyone else this drug hurt. Congrats to those that it helped. I would just say if you have gastro troubles really ask your physician GI preferably about this; for it to cause so much distress on one 30mg tab is pretty extreme. F 54 1 days
6/12/2008
 1  Depression Horrible dreams, tingling and numbness in hands and feet. Swelling of hands and inability to walk properly for several weeks. Pain in joints. Should be taken off market. Have tried to get off before but couldn't stand withdrawal symptoms, now I am trying again and will stick to it no matter what happens F 72 1 years
6/8/2008
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 3  fibromyelga pain F 50
6/3/2008
 1  Panic attacks I experienced a 3 hour panic attack. Had to cancel a long awaited trip because of it. Had leg cramps, shakiness, frequent urination, would have hot flashes and then cold chills. Lack of emotions. Last day I am taking this medication. F 37 4 days
6/3/2008
 3  Depression Teeth Grinding, 4-6 hour crash where you can almost pass out on your feet, sweating, Chronic Hives, servere weight gain 25pds, miss a dose get servere headaches and enter into an almost drunken fog. I have gone from Effexor to Cymbalta and I am much more pleased with the Cymabalta. Sexaul side effects are more mild, Consentration is easier, and I am able to control racing thoughts. The Sweating is not as bad as it was with effexor either. I have had hives while on both medications so no advantage there. The one thing I really do dislike is the crash. I am taking Cytomel to help with energy and didn't realize that was a potential side effect until comeing to look at this page. Literally you will be fine them five minutes later you can not keep you eyes open or your head up. The weight gain has been something I experienced on effexor but not nearly to the extent that I have on Cymbalta. With Effexor I was able to make a few modifications to my diet and was able to ge to my original weight pretty quick with Cymbalta no matter how strict I am the weight just doesnt seem to wat to come off. M 33 6 months
5/30/2008
 1  anxiety I sat in the tub for three days because I couldn't handle any stimulation at all. On my third day I felt tingling in my chest, hands, thought I was dying went to the ER. Seriously could NOT cope with the side effects at all. Was taken off of it and put on zoloft. I don't think people with anxiety that has any bit of hypochondria should be prescribed this. The tingling is not something I take lightly. it was terrible. F 25 3 days
5/29/2008
 2  depression, anxiety vivid, unpleasant dreams. some insomnia. constipation. i liked the slightly manic energy boost, but it didn't help much with depression. made me even more anxious. M 53 30 days
5/26/2008
 1  fibromyalgia pain Heart palpitations, nausea, diarrhea, tremors, anxiety, nightmares, disrupted sleep, fever/ went to ER!!! HORRIBLE--for me anyway! F 51 3 days
5/26/2008
 5  depression anxiety sweating, constipation F 46 3 days
5/21/2008
 2  depression/anxiety/BPD sleepy during the day and waking up and night. However, no dreams at all. That was good becuase all my dreams are bad. I have no motivation and feel tired during the day. Delayed ejaculation. I really think that it is cool that my bad dreams have gone away. but the side effects are really bad. first i took 60mg and was so sweaty and sleepless. Still sleepless even on 20mg day three. I am trying to finish my second to last semester of college and Im not doing well. I was on wellbutrin for about 3 weeks and I had lots of energy, yet my emotions were a little wierd, anger and some crying. I was sleeping well with wellbutrin which I thought was impossible with my insomnia. I take 900mg of Neurontin 10mg sonata 30 mg of Tamazapam, and 1.5 mg of Clonipin. Im not sure what to do. M 34 3 days
5/21/2008
 5  anxiety and depression gas, nausea, libido slightly down, climax difficult I have been on at least 8 anti-depression meds in the last 10 plus years and this is the first one that really helped with the anxiety, I had to quite smoking for the nausea to go away, but now that is has I feel a positive outlook on life again. M 38 3 months
5/10/2008
 1   25 of 40 some not even listed, blisters, numbness of face, loss of sensation in the mouth, on the one side that i had it. Twiching, legs shakes, 2 months insomina, vomiting, nerve pain, anxiety, yawning day one, head felt like a concrete block, loss of concentration, memory loss, unable to control writing, unable to finish off sentances, pupils dilating,unable to recall thoughts, feeling like my head was cut in half, unable to follow instructions and now an identification problem. Too excited... stop after 2 tablets but by then my face had gone numb. strangulation, and unable to walk in a straight line or identify people in the street or watch tv. Loss of feeling in my arms, burning in the stomach, and in the head. I am now hyper sensitive to other stuff. I have direeha since August 2007 and we are now in May 2008. My nerves each side of my stomach were going and my heart was racing. i wouldn't wish this one on my worst enemy, if i had doubled my dose to 60 i reckon i would be dead. Since taking it I have taken other stuff and it hasn't worked.. its made me feel worse not better. The neurologist says its because of my migraines . Unfortunatley I seem to have the change in sexual desires the minds kind of there but the body seems to be put off. I am hoping this might return. Other wise I kind of seem to be stuffed. F 38 6 days
5/10/2008
 1  SLE, raynouds, cerebritis Severe cerebritis flare up. Extremely painful headaches. Couldn't find much data on people taking Cymbalta with cerebritis and Drs. thought that Cymbalta was not the problem, but when I stopped taking the headaches went away. F 31 2 months
5/9/2008
 4  anxiety, depression, migraines Involuntary jaw-clenching, nausea, loss of appetite. Side effects disappeared after approximately two weeks. I don't feel a lot happier or free of worry, but depression and anxiety are most definitely less severe since I began this medication. Migraines are also less frequent (every four to five months instead of 1-2/month). I am definitely not disappointed with the results I've had with this medicine. Yes, the initial side effects are quite troubling but it was worth it. M 33 9 months
5/8/2008
 4  Depression constipation(still working through that), mild nausea (now gone), sleepiness I switched over from Prozac in an effort to combat my anxiety. Remarkable result with Cymbalta after only 2 weeks on 60mg. NO ANXIETY, NO WORRIES! I used to worry about everything. I feel much more centred. Like others, I feel somewhat lethargic and disinterested but I think that's part of my depression and will ease off once I reach steady state in about 4 weeks. Worth a try..I REALLY love the weight loss. 5lbs in two weeks without trying..just decreased appetite. F 41 2 weeks
5/6/2008
 4  fibromyalgia pain, anxiety a little nausea in the beginning but just a couple days. VERY tired in the beginning as well. Still somewhat tired after 3 months. Difficult to have orgasm. wish I had started it years ago. F 46 3 months
5/4/2008
 1  Nerve pain, OCD, Depression When I first took this drug I was ecstatic, because I felt sooo good! I did have some agitation, and definitely sweating. Also very vivid dreams, which was sometimes fun, and like being in the movie theatres all night. Spaciness, and very tired all the time. No sex life at all! I was extremely happy about Cymbalta at first, especially after just coming off Effexor, but now that I have been completely off of it for 5 days, I feel like I just woke up out of a 2 year COMA!! I cannot believe how crappy and tired I have felt over the last couple of years, thanks to Cymbalta! It was not real easy coming off 90 mg's, and I had a lot of crying spells, and felt so very strange. I fortunately switched to a very low dose of Celexa, so that helped making the change a little easier. Now that I am taking Celexa I feel so absolutely awake, and soooo happy, and energetic (like my old self). Oh yeah, and it's sure nice to have a sex life again!! F 42 2 years
5/2/2008

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