CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Fibromyalgia This is my first day on Cymbalta and was quite frightened by all the blogs on here. I am being started at 30 mgs and see how it goes. I am at a pain level of 8-9 so in addition I take oxycodone. I'm taking Prilosec to ease any nausea or stomache upsets that I have read about. I really hope this works for me because for the past 6 months I have tried everything from pool therapy, massage, reiki, far infra red sauna, and many pain meds. I feel like this is my last hope to get my life back again. F 58 1 days
5/8/2009
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 2  pain and depression severe night sweats, crazy dreams, breaking out in a cold sweat, thoughts of suicide, irrationality, shakiness, bad headaches, wrist pain, racing heart. please talk to your doctor!ask hard questions. listen to your body. F 43 3 months
5/8/2009
 4  Anxiety Slight constipation & lack of sex drive at first, but it went away after 2-3 weeks. So far it seems to be helping. I had a few side effects at first, but they went away after the first couple weeks. Now I really don't have any side effects, unless I forget to take the medicine, otherwise I get strange brain zaps. The past couple days I have noticed a rash on my torso, I do not know if this is from the medicine, although I have been on the medicine almost a year now. M 24 11 months
5/7/2009
 1  Depression Night sweats, headaches. I never felt like this medication helped my symptoms, but I never took anything I thougth helped. Now I question the diagnosis in the first place, because I've been antidepressant-free for a year and a half and feel great. So I can't really testify to effectiveness. Withdrawal symptoms are horrible: migraine-type headaches, sweats, tremor, nausea, dizziness, and a feeling of electrical shocks from my brain. I had trouble doing simple things like counting change, and I was terrified that wouldn't change, but my brain did heal itself! I got off Cymbalta with the assistance of my great doctor. It took me a good 4 months before I was back to normal, working normally. I had to take narcotic pain medications to get rid of the headaches so that I was able to sleep -- not something I wanted to do, but it was better than getting back on the Cymbalta. Feel free to contact me for moral support if you're suffering from withdrawal symptoms due to Cymbalta -- but make sure your doctor is aware of them also! F 27 6 months
5/7/2009
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 3  depression I was fine for the first month, but now I am experiencing severe joint discomfort in my wrists. It truly is odd. I will continue and talk to a professional about these side effect. Disturbed about the major joint discomfort in my wrists. I like the weight loss, but have also felt heart palpatations and have had extreme dreams. F 50 3 months
5/3/2009
 1  anxiety, nervousness, fibromyalgia, wavy dizziness, nausea, clenching jaw, headaches, feel of shaking inside, tiredness, feeling of bugging out about not taking cymbalta anymore. I have hypothyroidism, haven't taken anything for depression in years, also have fibromyalgia, and also on aspirin therapy. Recently seeing dr for anxiety, nervousness. Recommended cymbalta, took 1st dose of 30mg today at 11am and by 3pm, was feeling dizzy and extremely nauseas, next couple of hours, blurred vision on and off, clenching jaw, headaches, feeling of bugging out about not taking cymbalta anymore, pain in back of neck from clenching teeth...never had side effects this quick before. Will not take it tomorrow...wish me luck...will post again in couple of days. Do not take!!! I was really hoping it was going to help with fibromyalgia pain. F 36 1 days
5/2/2009
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 4  Anxiety/Depression I feel good! I'm on day 5 and read all these posts before starting. I was previously on Paxil which was not effective. I feel good! I know its too soon, but I do not have any side effects, I feel more alert, focused and worry-free. I usually have very vivid dreams but I have slept well and have had calm dreams the last few nights. I do not feel "zombie-like" or tired, in fact I feel like I have more clarity and energy. I am on the low dose, 30mg daily. I don't see any correlation to this med and diarrea and I am not worried about the effects of "going off it" as I plan to "stay on it" as long as I feel this good. I have advice for those who still suffer: Get some sunshine on your face, just a few minutes will make you feel great. Get an old dog, not a puppy, an old dog that Needs you, that you can care for and that will love you back. If you can't handle a dog get a fish. Smile at a baby! They usually smile back at you :) Think of positive thoughts even if you have to make them up. I dare you! Buy something new even if its just a pair of underwear. Women know this really does work wonders. Give it a fair chance, good luck. Aloha~ F 52 5 days
5/1/2009
 2  depression, fibromyalgia serious brain fog, careless, carefree, zombie type, laziness - mainly the symptoms from Fibromyalgia in regard to not completing task or alertness got worse. This drug is good if one wants to be feelingless. There is improvement in depression primarily is due to no presence of mind, body or soul. Does not help with the pain. I will continue to take it for another four weeks and than see if the side effects go away. I did try 60ml for two days and my mind could not handle it - back to 30mg. M 49 33 days
4/28/2009
 4  depression very vivid dreams, often nightmares. intense withdraw side effects if I do not take medicine regularly. dry mouth. It's hard for me to rate my experience on cymbalta, as I have been on antidepressants since the age of 14 and can hardly tell myself from the side-effects anymore. However, I have been on this medicine the longest and am most satisfied with the results. I'm a very happy, easy going person now, whether that's from cymbalta or years of therapy. I don't really notice the medicine unless I forget to take it, at which point I start to feel incredibly ill. This makes me not want to get off it so I keep putting it off. Maybe there's a part of me that's afraid to see what I'm like without antidepressants too. It's just been so long. F 21 4 years
4/24/2009
 1  Pain/anxiety Nausea, upset stomach, lose bowels, very fatigued. Very vivid and outragous nightmares. I hear it's generally used for depression but I've never felt so depressed in my life. I weigh more than I did when I was pregnant. Feel like I retain water. This drug almost ruined my life. Made me very emotional, from a combination of exhaustion and whatever the drug was doing to my brain. I would have outbursts some days and have terrible arguments with my boyfriend. Other days I would be extremely quiet and just want to be alone. I would purposely want to listen to depressing music or watch sad movies to add to my own misery. I feel like I have been on a rollercoater. I told my Dr. that I was feeling this way but was brushed off. I decided today I was going to stop and deal with the withdrawl.. So far I feel pretty bad, migraines and depression. I know that it will eventually go away.. DO NOT TAKE THIS. You'd be better off taking almost anything else. F 26 5 months
4/24/2009
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 1  Pain Sleepy, shaking, disoriented, stupefaction I have been on Wellbutrin for over 3 years. I started it for smoking cessation and it helped me go from nearly two packs a day to just a few a day. It also gave me energy and I had no side effects at all. No stupefaction effect that many get from drugs like Eleval and Pamlor (I took both to try to help with chronic pain – worthless. Now I wear a Fentanyl patch and the pain is well controlled and I have no side effects). I took one (1) 30mg pill and within two hours was asleep in my car because I got so tired and disoriented. I was at work at the time that I took it. Later that night, I was still groggy and my body was shaking, like I was having a low grade seizure or something. I slept on and off during the night, but was unable to go to work the next day because of the shaking and feeling of being disoriented. Your experience my be different, but if you are taking something that is working fine, don’t let a doctor “recommend” this. I won’t take this drug again and I would seriously consider not taking it if you are about to. Try Wellbutrin if you haven’t tried it. M 47 1 days
4/23/2009
 5  Severe Depression/Anxiety Extreme Fatigue/ Zombie like. By the Time I was 17 i had been on every anti-depressant under the sun. You name it, i've tried it. My doctor finally decided to put me on cymbalta, along with a mood stabilizer and an anitpsycotic for sleep. I can say nothing bad about the drug as long as it it TAKEN PROPERLY. The Drug worked perfect for me. The zombie like state at times and the fatigue were the only side effects i experienced. However if i missed a dose or two my world was turned up-side-down. i would go into manic episodes, and become extremely irratic. I would suggest this drug to anyone who can keep a regimented medication schedule. F 21 2 years
4/22/2009
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 1  fibromyalgia halucinations, BAD depression, thoughts of suicide, increased pain, sleeplessness,sweaty, dry mouth, head aches, and alcoholism!! I wouldnt suggest that anyone take this drug. it turned me into a completely different person in a matter of weeks. my first day taking it I had the worst anxiety of my life, very real haluctinations....after seeing my doctor a week later she told me I should continue to take cymbalta that the side effects would lessen but they didnt, they got worse. I started having thoughts of killing myself whenever I saw a knife or pair of sissors...then my friends and family brought to my attention that I was drinking alcohol non stop for over a month....priar to taking this medication I had never been a big drinker. I took cymbalta for 4 months and I can honestly say it made me CRAZY!! it took me 5 months after I stopped taking it to become myself again and get over the depression and alcholism. DONT TAKE THIS DRUG!! F 22 4 months
4/21/2009
 1  anxiety, depression, fibromyalgia brain fog, unable to think & speak clearly, tingling in head, blurry vision, frustration, depression, uncontrollable crying & rages, night sweats, headaches was on Zoloft for probably 10 years and thought I would try Cymbalta due to its claim to help fibromyalgia and that it wouldn't cause weight gain...felt much, much better on the Zoloft and just started back on it today... F 43
4/18/2009
 3  Depression/Anxiety Very vivid and distrubing night terrors,(I had two episodes where in one I saw someone being murdered and the others I saw the bodies of 3 females in a marshy like area)I was freaked out of my mind, I had problems staying awake and alert in the daytime, could not concentrate on my work, if I had missed at least two doses, I would become incredibly irritated and "zoned" snapping on my friends,co-workers and even my kids. I recently relocated to a new state and was having some adjustment issues and depression, I noticed my weight gain and my hair falling out as a sign of me needing help, I think that I could better manage those issues than the side effects. I will admit that it took the edge off when I was taking the 30mg, but when on the 60mg I felt that it only enhanced my other problems prior to taking this medication. I am now currently on Wellbutrin and I like it way much more than Cymbalta. I feel that I am more functional and can still do my daily activities, I agree with the other statements about being in a "Zombie" like mind frame. F 29 2 months
4/17/2009
 2  Fibromyalgia I noticed a lessening of the Fibromyalgia pain in a week, but the diahrrea and hair loss are not acceptable. F 62 3 months
4/17/2009
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 3  depression, anxiety, body aches first 3-4 months I was doing great, then disrupted sleep began, waking up every hour, night sweats, craving for sugar, low motivation to do anything I started on 30mg and went up to 60mg. Couldn't tolerate 60mg, it rendered me completely sleepless and with metallic taste in my mouth. The cravings for sweets are annoying. I feel like a junkie. As of today I'm switching to Lexapro. F 51 7 months
4/15/2009
 3  Generalized Anxiety Disorder Nausea (the first 3 days), chills, clenching jaw, excessive yawning, excessive sleepiness, foggy, zombie-like feeling, headache, loss of appetite I've only been on the 30 mg pill (take once in the morning) for about a week, so I'm trying to stick it out. I was very nauseated for the first 3 days, but that went away. What bothers me most is the excessive tiredness and yawning that hits me like a brick in the afternoon. I also feel like a zombie by then... really drugged up. The RN suggested I try taking it at night instead, so we'll see how that goes. This is the first time I've ever been on a psychiatric drug. It definitely has helped with my anxiety, which is why I'm continuing to give it a chance. Keeping my fingers crossed... F 34 6 days
4/15/2009
 1  Anxiety/Panic Attacks I took the first 30mg dose this morning. After about an hour my mouth felt like cotton. I became dizzy, nauseous and totally spaced-out. I just want to sleep and its only 3:00PM. I got a really good night's rest last night in order to start taking Cymbalta. The last drug I took was Lexapro which made me feel the same way. I only took it for one day and will NOT take Cymbalta again tomorrow. I am allergic to synthetic drugs such as Vicodin and Percocet, maybe that is why these drugs have such an effect on me. I want my Xanax back. It is much easier to control than an extended release tablet. I only took one .5mg tablet of Xanax in the morning and sometimes another later in the day if I needed it. I just wish I could get this med out of my system ASAP. My anxiety and panic attacks are much easier to take than the way I feel right now. I will definitely try to find a holistic alternative. F 53 1 days
4/14/2009
 1  Depression I have been taking it for 2 days and have had sever headaches, nausea, and feel as if I have a fever. After the first dosage I assumed i was getting sick. After the second I researched the side effects. I will not take this drug any more. M 43 2 days
4/14/2009

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