CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  IBS, Anxiety Horrible side effects. Nausea, Heartburn and chest pain, Severe Constipation, Burning feeling all over body, mainly in the kidneys, Very tired and unable to sleep. Noticed Dilated Pupils as well as major head aches. Low sex drive/Impotence, Worsened Anxiety and panic attacks. Very dry mouth with awful taste, aches and pains. Although it seems i was effected by every side effect possible, it may not be the same for others. But the suffering i went through with this drug was worse the then what they were prescribed for. M 24 5 days
30mg 1X day
2/29/2012
 3  depression/anxiety Terrible night sweats, zaps and nausea within 8 hours of missing dose, constipation, emotional blunting, sexual disfunction, yawning at weird times (while playing tennis), slower mental function It's helped depression/anxiety, but I'm not sure it has helped more than the Paxil or Celexa I tried before, meanwhile I don't like being a slave to it. I've lost about 10 pounds. I still have depressive episodes a few times a year. I feel unmotivated but not unhappy. Don't look forward or dread anything particularly. It's a weird place to be in. F 43 4 years
90mg 1X day
2/28/2012
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 5  Anxiety, feeling unreal only brain zaps when Id forget to take it Please remember, EVERYONE IS DIFFERENT. this drug helped me feel SO much better. chronic anxiety and depersonalization went away (not completely but effectively) even at the smallest available dose. Had to go off after I lost my insurance since it is a pricy drug. that was not very easy, but still easier than going ON zoloft which i am on right now and it sucks, lol. but its cheaper... will probably have to go back to cymbalta! remember everyone is different and its always worth giving a shot. again Ive tried lexapro, paxil, prozac and now zoloft. cymbalta worked the best by a long shot. Good luck and God bless! F 26 1.5 years
20mg 1X day
2/27/2012
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 2  Anxiety GI upset, change of personality After a therapeutic level of Cymbalta was reached in my system, I thought Cymbalta was great...I was feeling more relaxed than I had been in a long time. I ignored the stomach pains and constipation because I figuerd I'd rather be happy and have to take an occasional stomach med. After a couple months, I realized I had nothing to say anymore...I could not make conversation to save my life. I wasn't stressed anymore, but my self-esteem was shot as I thought I was the most boring person ever. I ended up tapering off over a couple weeks and am back to square one with my anxiety, but have a personality back. F 28 5 months
30 mg 1X day
2/22/2012
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 1  Trauma and Depression Side effects HORRIFIC......grinding teeth, dizziness, severe weight gain, crying all the time, severe low self esteem, non exsistent sexual feelings or other, zombie like state, lack of energy! WITHDRAWAL SYMPTOMS!!! OMG absolutely HORRIFIC!!! Reduced tablets to low dose and carefully weaned myself down to taking no tablet.....As a Result, suicidal thoughts, collapsed and was rushed to hospital, suspected cardiac arrest, Brain Zapps(Imagine chewing on silver paper and X that by 100), weird brain sensations!! Grinding of teeth... Off the tablets 6 wks now and still suffering!!! My doctor has issued the drug a 'yellow card'.......REPORT THIS DRUG TO YOUR DOCTOR! Now I am off this drug, I can honestly say, it did me no good what so ever and I just hope the Brain Zapps go......feel terrible..... I have put on over 3 stone in weight, have no energy and had virtually given up on life!!! F 48 2 years
60 1X day
2/18/2012
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 1  Major depressive dis., Gen anxiety Read what other people have said here!! F 62 2 years
120mg
2/17/2012
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 3  Depression and anxiety I ahve not had any that I am aware of EXCEPT when I tried to switch from Cymbalta ( expensive even with great insurance ) to another anti-depressant that was available in a generic form. I ended up with the WORST headaches ever - "cluster headaches" that I would never wish on my worst enemy. I went back on Cymbalta and presto - headaches gone. THis is a scary thing for me as I do not want to take it forever but right now I am scared to even try to go off of it. F 50 4 years
60 1X day
2/15/2012
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 4  Fibromyalgia Initially I was very nauseated (3 days). Now, I have extreme hunger and weight gain Although it hasn't been a miracle drug for the fibro, it has greatly improved the quality of my life. I feel like I'm really living again. F 50 4 months
60 1X day
2/13/2012
 1  Stress Fainting, couldn't breath, shaking, blurry vision F 35 1 days
60
2/13/2012
 1   Most listed by others primarily gastrointestinal initially, later as described PLEASE HEAR ME THIS IS A DANGEROUS DRUG !!!! When I first started on this drug I had GI upset buy my doc encouraged me to continue (2008) as the benefits would be great. Within 3 wks I felt so much pain relief I felt like a "new person" so I treated the GI problems symptomatically with GI MEDS. Then the personality change began, since I live alone I did not realize it until road rage began. I tried to tell my doc this but she just blew it off ( I later discovered that SHE was being paid by the drug company for a drug "survey") Then things began to happen such as: I would be driving and have no idea where I was going, woke up several times in my car in my pajamas, packages would arrive at my home from the TV shopping channels addressed to me, I had NO MEMORY of ordering them, I overdrew my checking account several times ( HAD NEVER DONE THAT). Then the pain slowly, along with "brain fog" and "brain zaps". The doc did not want to hear about the brain issues she just wanted to up the dosage to address pain issue( again the "survey"). So I asked a trusted pharmacist (an older man) he said off the record "OH YES very common, don't you know this is a legal form of Ecstacy?" "Your brain is craving a higher dose, this is a BAD DRUG". That was enough for me ! He told me how to wean off of it.... yes counting those little beads, even doing that it was hideous ! I bet it will be taken off the market soon, if no F 62 7 months
60 1X day
2/13/2012
 5  Bo-polar,depression,Borderline Dizzy if I forget to take it I have been on TONS of other meds in my 20 yrs of dealing with my Illness and this is by far the BEST ive ever had very good for my depression, but not alone I take it with other drugs F 34 5 years
60 2X day
2/10/2012
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 1  fibromyalgia/depression extreme restless leg syndrome, involuntary arm and leg movements, difficulty breathing, vertigo, "spaciness" it was almost as if i were allergic to it F 52 5 days
30MG 1X day
2/10/2012
 1  muscle pain, anxiety Extreme dizziness upon waking, sweating profusely, clammy hands, fainting, burning pain in sternum, nausea F 31 1 days
60 MG
2/9/2012
 4  Fibromyalgia and Depression Weight Loss, initially nausea, but the nausea subsided after ~3 weeks F 33 8 months
60 mg 1X day
2/8/2012
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 4  Low back pain and depression I have not had any side effects and hope I won't. So far it has lessen my low back pain and made me more connected with life. Started 30 mg for 15 days before going to 60mg and it has worked fine. M 30 3 weeks
30mg/60mg
1/30/2012
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 3  Clinical Depression and anxiety weight loss, major loss of appetite, trembling, trouble sleeping F 19 4 months
60mg 1X day
1/29/2012
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 1  Mild depression/anxiety Took one capsule at 11.30pm, woke up with uncomfortable tummy pains at 4.30am, felt like upper stomach was burning, dizziness and extremely nauseas with a need to dry reach, without vomitting. Weak muscles, bodily tremors, chills and slight fever. The whole day experienced nausea, tummy aches needing to go to the toilet frequently, major loss of appetite, slurred vision, jumbled words, decreased expression/apathy, quiet, mild shakes, constant yawning and extremely fatigued My brief experience is enough to put me off going further or 'giving it time' to work. I've always self managed my own symptoms over the years and recently felt the need to trying something different in combination with possible therapy. BUT, I know that I can be without this. 2 days later I'm still experiencing effects, still a bit foggy in thought with tummy cramps (I was so zombified the last few days and haven't yawned SO much in my life!) I felt like I needed to be hospitalised. I regret not doing some self research on this before to understand potential effects on my body and state of mind. Regardless of whether the effects are temporary, I'd rather try and be overall healthy the natural way. I know everyone has a different experience - for some better/worse than others. Before turning to these drugs, if any of you have even that smallest bit of motivation and zest for life- find the things which make you happy and get on those natural highs instead, it's the best kind.. you don't know what kind of (permanent) physical, mental and emotional damage these drugs can cause. Also not a bad idea to read experiences and weigh the goods and the bads (for me, the negatives def outweigh the positives!) Getting on theses things could make things even worse. This experience has taught me a lesson for life. Try not to give up on hope for better days ahead!! And for those on here who have already mentioned this - I agree, this stuff is lethal. Please take care and good luck! F 28
30mg 1X day
1/29/2012
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Patient History
 2  depression/anxiety constipation,exhausted,very hungry This medication so far hasn't been the best. I am only 16 years old and my psychiatrist suggested this. Mostly older adults take this medication but I have major depression and GAD. My suicidal thoughts have still not gone away. I guess I should wait a few more weeks. I am hoping it wont get worse. F 16 7 days
30 MG 1X day
1/25/2012
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 5  DDD/Back pain and nerve pain Nausea the first week and "wired" but that wears off. Now I have night sweats. BUT the less pain makes it all worthwhile. I have my life back. F 46 2 months
60 mg
1/22/2012
 5  depression, anxiety None. Great! I have used and had to quit many anti-depressants, but this helps a lot, takes the edge off so I can do the counseling and support group work needed. F 44 2 years
30 2X day
1/20/2012
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