CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Depression, chronic pain The withdrawals are worse than anything I initially experienced. My pain now is 100% worse, now have IBS, feel like Max Headroom 50-60x a day. Pure hell. Coming off narcotics was a cake walk compared to this! Don't take it. Please. I stopped it over 4 weeks ago and I am in literal hell. F 41 10 years
90mg
10/29/2016
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 5  Major depression, severe anxiety Weight gain but this can be controlled, poor cognitive function, loss of short/medium term memory Was prescribed this drug to deal with treatment resistant depression over a year ago and it was so effective that I was able to cease taking it without any side effects..suffered a relapse in recent times and resumed taking the cymbalta..it's cheap and cheerful and it works..I put on more than 14 pounds the last time I was on it but I am watching my weight this time..while my cognitive function is shocking and my memory even worse, I have got used to it..it's a small price to pay.. F 53 1 days
60
10/2/2016
 4  Depression Overall, I just feel normal. If I missa dose--dizziness and freaky dreams, which used to skeeve me out, but kinda find them interesting, now, in a way. Stil wonder about long term use tho. M 62 10 years
60 mg
9/22/2016
 5  Fibromyalgia, neuropathy, etc Dizziness Wished I had not been misdiagnosed so many times over the years and finally got the right diagnosis and medication. It has helped me tremendously F 45 5 weeks
30 mg
9/8/2016
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 4  Back injury I initially experienced major insomnia- still a minor issue (I've never been a good sleeper). I suffer nausea most days till about 2pm. I get major hot flashes and night sweats. I have put on 5 kilos (not ideal) and it has messed up my periods. On the plus side my pain is manageable and my state of mind is not as bleak as it was. I would recommend it. Side effects I can put up with. F 41 2 months
60 1X day
9/5/2016
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 1  Depression anxiety Was on Prozac 20mg and it was making me more depressed. So my Dr switched me to 60 mg of Cymbalta. Took my first pill at night went to sleep not thinking about it at all because I knew it could take weeks before it started working. About 1 a.m I jolted up out of bed. My heart was racing I was cold and hot at the same time. Couldn't catch my breath. Was very scary felt disoriented. Came to hospital and they gave me something to reverse it. The Dr at hospital said that was a very common effect with Cymbalta. F 44 1 days
60 mg
9/1/2016
 5  Neck pain/ osteoarthritis Constipation and weight gain This drug has been life altering. I was ready to end it before I started taking cymbalta. I am enjoying life again. I feel the best when I also practice yoga a few times a week and get regular massages. F 46 1 years
60mg
8/22/2016
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 5  Neck pain/ osteoarthritis Constipation and weight gain This drug has been life altering. I was ready to end it before I started taking cymbalta. I am enjoying life again. I feel the best when I also practice yoga a few times a week and get regular massages. F 46 1 years
60mg
8/21/2016
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 1  Depression Did not help my depression and caused me to have suicidal thoughts. I was taken off and experianced withdraw so bad that I now back on and slowly coming off. I had chest pain, heart palpitations, vomiting, headache, rage, mood swings, and more Other drugs can help just as well, without the terrible side effects F 17 6 weeks
60mg
8/11/2016
 1  Major Depressive Disorder Increased sever social anxiety, severe short term memory loss, continuously worsening depression. Feel like I'm out of touch with reality. Feel almost child-like. After 10 years on this drug, and trying to go off of it at least 4 times, I know the horrible side effects of withdrawal (especially the bothersome brain zaps), which is why I stay on it even though I want nothing more than to be "normal" again. F 37 10 years
30mg
7/30/2016
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 4  Arth9 Stomach pain F 72 10 days
7/26/2016
 2  Fibromyalgia pain Extreme headaches tiredness brain fog weight gain hungry all the time ibd now stomach aches dizziness anxiety Have extreme headaches having a hard time with them sometimes I feel lost in a fog hard time remembering things hungry but can't eat much without stomach ache still have pain had anxiety in the beginning of dosage which was 30 mg F 54 10 months
60mg
7/25/2016
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 5  Depression Withdrawal when missed dose. Exhaustion, horrible anxiety, crying, unable to work or function. Withdrawal symptoms always happened within 24 hours of missed dose.NOT recommended to skip or stop suddenly! Controls worst of my depression and anxiety. It seems side effects people report depend on the reason they are taking the medication. F 42 10 years
60
7/15/2016
 1  Anxiety Sweating, muscle and joint pain, body temperature regulation, brain zaps, headaches, mood swings, dizziness, nausea, fatigue, brain fog, breathing problems, heart palpitations, feelings of exhaustion and apathetic to almost everything!!!! I wish I would have never taken this medicine!!!!😢 Also, I'm pretty sure I have taken this longer than 10 years but that was the longest option to choose from. I wish I had never taken this drug!!!!! The. side effects were manageable but I didn't know the things I was experiencing were related to the medicine until I began researching and realized others were experiencing the same things. I am now in week 6 of tappering off of 60MG and the WITHDRAWLS are terrible. I can't sleep, my muscles ache, it is difficult to breath, crying, mild tremors, brain fog, brain ZAPS which I have described to my doctor for years by saying that sometimes my brain feels like it mis-firing or short circuiting. I didn't know it had a name until a few days ago. I will get through this but I nor anyone else should have to suffer through withdrawals like this from a drug that was "Prescribed"!! F 45 10 years
60mg
7/6/2016
 4  Anxiety (+depression/bipolar) Weight gain (+10kg) At summer time I feel some restlessness, difficulties to concentrate. Sometimes impulsivity in the way I answer/react (as compared to what I would have done otherwise) I was treated with 60 mg when I started the treatement. then switched to 30mg. the first two years, I stopped it 6 months after being better (my doc was ok) but the symptome reapeared the next year. For the last two years, I`ve taken it continuously at low dose (30mg). F 37 5 years
60/30 1X day
7/1/2016
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 1  Pain Hospital er . Flu like symptoms.anxioty sleep deprived but exhausted weak and generally felt like dying Doc put me up from 30t60 ,after third day on higher dose woke up at 4am puking ,shaking . Could.t get up got ride t er. I hate narcotics,but this feeling is worse than anything ive ever takin for my pain. Pain management is th biggest joke now!! F 48 2 months
60
6/29/2016
 1  bipolar depression with anxiety Weight gain was(30Lbs), sweating, memory loss I started taking it in 2004. At first I hated the sweating and weight gain. After awhile I learned to cope with it and my anxiety was about 80% gone. My depression disappeared. It seemed as though I was never bipolar and I was textbook bipolar!. I was able to cope with even with an abusive partner. The issue is you cope too well. You become desensitized to everything. Nothing feels normal. You just go through the motions of life. I didn't think of my children's needs or emotions because I had none. I weened off after 5yrs of taking it. Stepped down from 60 to 30mg then off. I did take prozac while weening. I was off for two months and asked to be put back on it after all my bipolar symptoms resumed. I took it and was back to normal except I had anxiety. Now after being on it for almost 16yrs I weened off again with prozac. I've been off cymbalta for 3 months. Still on 40mg of prozac, but hope to wean off that, too. The reason I wanted off is memory loss. Forgetting words, there meanings and how to pronounce them. Driving and not knowing where I'm headed after a few minutes. Not able to enjoy sex. Just loss of feelings. After 3 months off I'm still without memories from the past, have issues remembering the date, names, recipes, appointments, to thaw something for dinner. It's impossible to remember my meds or appointments. I don't have signs of depression but am on 40mg of Prozac. I just want to remember. F 40 16 years
90 1X day
6/20/2016
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 1  PTSD Symptoms After 4 1/2 years on Cymbalta(30mg), and still dealing with Depression from PTSD, I had a 24 hr psychosis event and ended up in the emergency room. My doctor then thought it best to bump my dosage to 60 mg. That extra 30mg of Cymbalta , almost was the last nail in my coffin. Within a few months I was always irritable and angry verbally abusive to my family. My anxiety was on full blast and I couldn't turn it off, causing tremors and restless legs. I slept 3 to 4 days a week, and I had extreme depression. I had migraines and lived in a fog and couldn't even comprehend basic responsibilities , like paying my bills or working my cell phone. I showed paranoia symptoms and my blood pressure would raise or drop at any given moment, I was often dizzy or light headed, probably from the raising and falling of my blood pressure. My heart would beat rapidly much of the time, and my sleep patterns way off. Because many of these symptoms resembled extreme PTSD symptoms and my VA doctor so many mil I am experiencing residue side effect, after a few months without Cymbalta, mostly in tremors and restless legs. Also there is alway an amount of anxiety and nervousness that I never had before, and now rarely goes away. M 50 6 years
60 mg 1X day
6/10/2016
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 1  Nerve pain depression anxiety Brain zaps, virtigo, disorientation, cognitive empairment Also because it is expensive I fight with insurance to get it covered M 26 4 years
90 1X day
6/5/2016
 3  depression & fibromyalgia none that I am aware of, only first couple of weeks, severe nausea so bad it made me vomit and also headache. same when I stopped taking it, lasted the same 2 weeks. I AM MORE CONCERNED ABOUT IT'S LONG TERM EFFECTS on my brain and body but I really don't know what they may be? I stopped taking it about 3 weeks ago because I am just concerned about its long term effects of which I have no clue what they may be. I've had headaches since I stopped -I am not sure if it's due to the Cymbalta withdraw or maybe it s a long term side effect? but I don't know what else would be causing them, since I eat very healthly and do a lot to avoid anything that can cause cancer. my primary doctor said ulcers can cause headaches?-so I'm seeing a specialist to see if that gets rid of the headaches? Cymbalta definitely worked for depression, not sure about fibro pain. I am looking into taking Niacin vitamin for depression now. F 52 8 years
30mg 2X day
6/1/2016
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