CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Anxiety and pain Terrible profuse sweating, headaches, dizziness, tinnitus It sucks and shouldn't be prescribed F 59 2 months
20 1X day
8/10/2022
Email
 1  Fibromyalgia Extreme Nausea, extreme fatigue, tingling tongue, irritation to light sound and temperature. Sweats and chills. Loss of appetite. Changed ability to taste. Miserable felt suicidal to escape irritability to sounds I took for two days and am off for two days. I don't know if it helps with pain because the side effects were unbearable. Dry mouth is not a correct description it was as if my tongue had electrical currents. Hearing loud sounds (like a loud car or motorcycle drive by outside) made me so Irritated I wanted to die or Kill someone! Insane for two days in! My tongue is finally starting to feel normal and I was able to drink coffee this morning! Irritability and tiredness is starting to subside! Scary horrific! Would not recommend F 44 2 days
20mg 1X day
7/31/2022
Email
 1  Chronic pain Upon attempting to stop med had severe issues for month and half. Not sure how well it actually worked after using for 6 months. Used for chronic pain related to C2-T1 lamenectomy and fusion. Stopping drug was debilitating due to brain zaps and vertigo which led to nausea and inability to function. I would never take this drug again as withdrawal (yes withdrawal) is horrible and lasts for months. I tried to wean off it as doctor recommended. Even went so far as opening pills and removing half the med. Would never recommend due to issues with stopping medicine. Think long and hard about taking this med. Brain zaps are truly debilitating and should be included in disclosure as can last months. M 64 6 months
30 2X day
6/20/2022
 2  depresia I write ir Lithuanian language. As nezinau ar mano savijauta yra nuo Cymbaltos vartojimo.As jauciu kiekviena diena galvos skausma virsuje galvos centre,spengia ausyse,kiekviena diena skauda krutine,sokineja kraujo spaudimas,sirdies ritmo sutrikimai ir ttttttttt..... as bandau mazinti Cymbalta vartojima nuo 60mg ,kiekviena diena nuimu po 7 granules,jau pasiekiau 30mg simptomai nesikeicia,sergu kiekviena diena.as tikiuosi man pageres jei pavyks man nutraukti vartojima Cymbaltos.As pavargau sirgti kiekviena diena-sunku... M 40 8 months
60 1X day
5/29/2022
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 1  Depression, Anxiety, Derealization The brain zaps are unbearable, just showering and brushing my teeth is exhausting, no joy in things I used to love, no friends because they think I'm insane.can't work a real job because of the fatigue even with insane amounts of caffeine. I'm like an angry zombie I got on this to be helped not crushed. If you have depression or anxiety PLEASE look at holistic ways FIRST. I wish I knew diet and exercise and drinking enough water can help with symptoms M 24 4 years
60 1X day
5/27/2022
 3  Lupus Pain Light sensitivity I'm horrible with taking medications anyway so taking this med was a long shot for me. I was in so much pain before med. i took it at night. I woke up to horrible gas and the urge to poop. I stood up I felt extremely dizzy. I had instant diarrhea. My vision was blurry. My nerve pain was gone but I felt horrible. Mouth was dry. Constantly yawning. F 28 1 days
30 mg 1X day
5/17/2022
 1  Anxiety and Depression - nausea - intense brain zaps - hard to breathe - increased anxiety -anger -intense sweating - headache - muscle pain - heart palpitations - tingling -loss of sex drive currently on day 6 of withdrawal and it's pure hell. do not take this drug ever unless you want to be dependent on it. Was taking 40mg then went down to 20 for a couple months. Started to taper off my taking 20mg one day and then not taking it the next for about a month and now i'm completely off of it and i have never felt worse. I wish i never took this medicine. F 19 5 months
20mg 1X day
5/13/2022
 1  Depression Horrendous nausea episodes with pressure in the head and muscle tremors M 44 0 days
30mg 1X day
5/10/2022
 1  sexual harassment felt dead inside. no joy. creativity gone. Health plummeted. Gained a lot of weight. Aggression. Irritable. No sex drive. grinding damaged my teeth. Nausea. Insane brain zaps. Brain fog and scattered thoughts. Acted weird. Sex drive has not returned almost 2 years later. What a horrible drug. They pass it out like Halloween Candy. The withdrawal took over a year while other antidepressants only took weeks. What a nightmare. They give this to women who are being sexually harassed so that you are more compliant with the abuse. Psychiatry is steeped in misogyny. F 59 1 years
100 mg 1X day
5/9/2022
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 1  Depression and anxiety Constant fatigue, no emotions except sadness, 20 pound weight gain, INCREASED body pain. No motivation, very easily aggravated. Lilly KNOWS that this drug is TOXIC, yet all they do is add more warnings to their pamphlet of bullshit. It needs to be taken OFF THE MARKET, and prescribed ONLY for those trying to wean off. I have weaned down from 80mgs to 30mgs, and now it's very hard to decrease without returning depression and anxiety. PLEASE DO NOT TAKE IT!!! F 65 11 months
80 mg 1X day
4/29/2022
 1  suspected fibromyalgia Extreme nausea, dizziness, confusion/brain fog, muscle tightness/stiffness most noticeably in the neck, chin, and face areas, worsened anxiety, tingling sensation all over I felt slightly off the first day I took the pill and thought I could tough it out but the second day was enough for me to call it quits. I don't think I needed to be prescribed this drug, even though I struggle with anxiety, I don't think I have fibromyalgia. I have only felt "fuzzy" from medication one other time when I was taking antibiotics I ended up not needing as well. I hope this medication helps those who need it, but I will keep my friends and family away from it unless it's an absolute. F 26 2 days
20 MG 1X day
4/27/2022
 2  Fibromyalgia Back Pain Anxiety Beginning - the first couple of days taking this medication was hell. Every side effect I had it. Nausea, insomnia, cravings, brain fog, loss of appetite, etc. On the medication - it really did help with my anxiety. I felt more at piece with things and less agitation. On the other hand, my pain and fibromyalgia got worse. I had complete muscle failures (went to the hospital multiple times) extreme fatigue (had to go part time), headaches and sensitivity to light, sound, etc. It would randomly come as well. I could have two good days and four bad days. Etc. So unlike me. Withdrawals - I weaned off the medication. Insomnia, ramblings, agitation, loss of concentration, nightmares (scary ones about real life, never in my life before did I have anything like this) and constant scratching. Omg the dry mouth this gives you is crazy bad! Throughout the whole experience. Also really had heart burn, constipation and general stomach issues throughout. To be honest, this was definitely not the drug for me. The doctor thought it might help with the pain and muscle spasms I was having but it just made it worse. It has made me realise though, I might need to try a different anti-depressant or anxiety medication for that. F 25 6 months
60mg 1X day
4/23/2022
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 1  Depression I started taking this drug for depression. Do not start taking it ever ! I felt good but gained been weight rapidly . No sex drive ! About three years ago I tried to get off of it. I could not function .. debilitating brain zaps that made me need to sit down . I was insanely dizzy and my eyes felt like they were wobbling in my head . I could not work. I had to get back on my 30 mg dose . This year I decided to rid myself of this poison . My NP had no clue how to help me get off of it . I stared taking 20 mg and this was easy then I after a while I went to 20 mg every other day . Then I stared counting the pellets and reducing the amount taken by a few pellets each week. It's been six months of a nightmarish hell trying to get off of this drug . Anxiety , inability to sleep and insane night terrors. Everything I drop the dose I feel worse . Then after I adjust to the lower dose I begin to feel normal . Hoping to be completely off of it in a few more weeks . This drug causes dependence. Almost impossible to get off of . NEVER start taking it. 54 7 years
30mg 1X day
4/16/2022
Email
 1  Major depressive disorder Head “zaps” Nausea Fatigue Dizziness Lack of motivation Increased anxiety This drug should not be on the market! It is pure hell and even worse when you try to get off of it. It did absolutely nothing for my depression. I am praying that I will be able to wean off of it as soon as possible. In the meantime, it is pure hell. Please do not even consider it! The drug maker should be sued! F 65 10 months
60 mg
4/14/2022
 1  Anxiety Vomiting, dry mouth, made my anxiety worse, tingling in hands, neck dystonia and severe muscle spasms. It was horrible! I only took it for one month then stopped cold turkey. Do not ever stop this medication cold turkey! Every single symptom got so much worse. I had no idea how dangerous this med is! F 53 30 days
30mg 1X day
3/24/2022
Email
 1  Depression and back pain First off don't even take this drug. It's horrible. Forget about sex. You won't have a sex drive. And if you miss a dose prepare yourself for a rough path ahead. I've been taking this for 5 years. Recently my insurance company has been screwing me around with getting it filled. And I was playing a game of tag with my dr. All while being off this drug for 2 days. It's been 5 days now not having it and it's been the most awful experience. Tired, fogginess, brain zaps every 30 sec that last from the time I wake up til I go to bed. I've been wanting to get off of this due to the side affects of it. And at this point for me there is no time like the present since I still don't have my prescription filled. I'm going to detox this shit out of my system and never take it again. THERE ARE OTHER EFFECTIVE MEDICINES OUT THERE. STAY AWAY FROM THIS F 38 0 days
60 1X day
3/22/2022
Email
 3  Depression and severe pain Dizzy, nausea, insomnia. It seems to be helping a bit with the severe pain. Not sure about anxiety - insomnia. Trying to give it a trial because the pain is killing me. I am severely agoraphobic. F 68 10 days
60 1X day
3/6/2022
 1  Anxiety, depression Memory loss, brain fog (for the very things I can recall), aggression, suicidal thoughts, depression This medication has been the ruin of my life. Will probably spend the rest of my life in prison. Be wary of ANY medical professional that trivializes concerns you have regarding the medication. M 49 21 days
60 1X day
2/21/2022
Email
 5  Depression No side effects When the generic form came out, after 2 weeks I had extreme vertigo. Stopped the generic and went back to Cymbalta. I have not had any problem since. Helped me tremendously. Depression has been with me since I was a child. I found out later in life it runs in my family (mother and her sisters) It changed my life. F 74 15 years
60MG 1X day
2/20/2022
 1  Depression Did NOTHING for depression! Felt exhausted and nervous at the same time. All I want to do is sleep. Made me easily angered and impatient. Now I get to look forward to the HELL from weaning off of it. I wish I could SUE the manufacturer. DONT TAKE IT! It does NOTHING to help! F 65 0 days
80mg
2/20/2022

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