CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2744 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  minor depression, migraines The cymbalta kicked off anxiety and insomnia big time. It was too stimulating for me. Went off and now using viibryd F 31 2 months
60 mg
8/15/2012
 1  Trigeminal Nueralgia Extreme body sweats, all over drenching sweats. Ringing in the ears. Worked the first couple of weeks. went from 30mg to 60mg. It all went downhill from there. Total body drenching sweats hourly. restless in late night and only really got to sleep at 3pm. Kids would be up and going at 7:00am. so only 4 hours of sleep for me argh. weened off and stopped taking altogether from dr. Nightmares, vivid sleep walking/talking episodes. muscle spasasms, deafing ringing in the ears. Buring sensations on side of the face and ear. I had asked about side effects of withdrawl and dr's siad just minimal. I hope this is not minimal... F 43 6 months
60mg 1X day
8/11/2012
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 4  Panic disorder,depression None at all what so ever for the first 5 years,then my agitation got bad and I seem to be more negative than I used to be,but boy it does give you bouts of energy here and there! So I will sacrifice the mood swings sometimes since it totally blocks my panic attacks. The only other thing,my memory short term is not as good,but tried years ago to taper down to 30 mg and my anxiety was back,and believe me I have tried every anti depressant there is,this is the only one that would totally block panic without weight gain! F 43 10 years
60mg 1X day
8/10/2012
 3  chronic back pain herniated disks Weight loss,abdominal pain, excessive sweating for 5mths, rages,mood swings recently,jaw clenching,nightmares past 2wks F 36 9 months
60mg daily
8/7/2012
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 1  back pain Weight gain, unrelenting nausea, sweating, drowsiness. Most important: it did little or nothing for my back pain. My Dr. wanted me to try this drug rather than using chronic vicodin and I agreed because I respect his opinion. My pain became unbearable and all I was offered was Cymbalta; not even a good placebo. After 2 months on Cymbalta I asked my Dr: do you even care about my back pain? Do you think that Vicodin is in any way, shape or form a "worse" drug than Cymbalta? Vicodin works and has few side-effects, the Cymbalta side-effects are terrible and it doesn't work; and stopping it is worse than stopping Vicodin. After a little badgering, he admitted that Cymbalta was a bad choice and I got my 6 month rx for Vicodin..that was 4 months ago, pain pretty much gone and I only use it prn. Nobody should be prescribed Cymbalta for chronic pain, nobody. F 50 60 days
60 1X day
8/1/2012
 3  back pain WEIGHT GAIN!! sweats I have been taken cymbalta for back pain, 30 mg did nothing for me however the 60 mg helped for about 2 months. I gained about 20 pounds!!! Horrible!! The fat on my stomach sure can not be good for my back!! I wanted off of it. So I decided to stop. BAD IDEA! DO NOT GO COLD TURKEY! I was so sick the 3rd day off of it, felt like I had the flu. I immediately took it again and called my doctor. My doctor brought me down to 30 mg every day for 2 weeks and then every other day. The only side effect now is heart palpitations, which is just annoying. I still sweat like crazy. Hoping that will go away soon and hopefully I can loose this weight I gained! M 53 7 months
60 mg 1X day
7/27/2012
 4  Bipolar 2 No side effects- no weight gain- has been a great med for me and now I am on Lamictal with it and the combo seems fine. It is very difficult to reduce dosage though so beware F 39 3 years
160 mg
7/26/2012
 1  lower back pain This is a horrible drug. I gained 25 pounds in 5 weeks, I have been constipated, gassy, having heart palpitations, insomnia, my hair is fried and I do not use ANY chemicals on it, I keep breaking out F 42 35 days
40mg 1X day
7/26/2012
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 1  Fibro, CFS, depression Gained 25lbs in a year, developed tachycardia (115/minute), increased blood pressure. Tapered for 4 months before stopping. 2 days after taking last pill got extremely ill, nausea, emotional, depresses, anxious, thought I was having a nervous breakdown. Took vitamin c, d, b complex, wore seabands. 9 days off and still experiencing symptoms. Heart rate has decreased to 86-90. F 31 1 years
60
7/25/2012
 1  back pain I have gained 20 pounds in 5 weeks ...no joke F 42 1 months
40mg
7/25/2012
 1  depression and pain you have no idea how bad this drug is until your pharmacy needs to call your doctor and you are without it for just ONE day and go into full blown withdrawals - or when you attempt to get off it. You will start counting the pellets inside the capsule to reduce the dosage to get off this drug. HIGHLY addictive. You don't realize it until you want off... nightmare medication unless you are on it forever and good luck with the long term side effects... research!! F 50
60 mg 1X day
7/25/2012
 5  depression In the first 2 weeks I had nausea, lack of appetite and i lost some weight. It went away after 2 weeks i just had to stick it out. Cymbalta is hands down the best anti-depressant for me. I tried others and cymbalta is the best. It helps with my anxiety too. I have had no sexual side effects except being able to last longer in bed. M 25 3 years
90 mg 1X day
7/13/2012
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 5  depresion,anxiety,pain At first had suicidal thoughts but that lasted only a couple weeks,then works great. I will not stop taking it,it is the ticket for me. M 52 2 years
90 1X day
7/11/2012
 5  Ptsd and genelized anziety disorder Agitation I think it's the best and safest ssni I've ever tried and haven't been in the hospital for over 6 months. Cymbalta saved my life. M 40 10 months
1X day
7/10/2012
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 1  fibromyalgia The worst side effects were terrible swelling of my feet, ankles, legs, hands and wrists, as well as increasing difficulty urinating. If I hadn't figured out myself that Cymbalta was causing these problems, I honestly believe it would have killed me! M 57 1 days
60 mg 1X day
7/9/2012
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 3  depression/anxiety and UCTD pain excessive severe sweating (for about a month, then it subsided), upset stomach (this too improved) This medication has helped with my anxiety/depression and moderately with my pain. I had a hard time initially with the excessive sweating, it was to the point where it was embarassing and obviously abnormal. Fortunately this symptom improved after about a month. F 28 1 years
60 1X day
7/8/2012
 2  depression I broke out in hives on my cheeks it was very itchy and burned went to hospital once they said it was contact dermatitis then my other cheek did the same they say It's the cymbalta. I read online you should not take this with trazodone... I believe my psychologist is a moron because I've had problems with other depression Meds mixed with trazodone. I'm going to see if I can get this changed. I'm not sure if its the mixture or if its just cymbalta F 25 7 days
30
6/29/2012
 5  Fibromyalgia Pain & associated Depr I can only think of one possible side effect, which is dizzyness &/or lost seconds as I drive or type or write, because my mind will wonder to things that have nothing to do with what I am doing, as it is happening now due to Fatigue from this Fibro disease. I can only think of one possible side effect, which is dizziness &/or lost seconds as I drive or type or write, because my mind will wonder to things that have nothing to do with what I am doing, as it is happening now due to Fatigue from this Fibro disease. I take so many other meds that it could be triggered by as well. However, due to full body muscle spasms at night which were uncontrollable, my Primary Dr. doubled my dose of Cymbalta, because I had already been on the Flexeril 10mg 3 x day, she felt that this was another brain reaction. The problem with dizziness and the missing time by my weirding out while driving or walking or typing or writing, all became worse & my Pain Manager (Dr. Cathy X Gao) said that no one should prescribe that high a dose of Cymbalta. I am now back on my regular dose. M 46 2 years
60 1X day
6/28/2012
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 5  Depression, GAD, Insomnia -Excessive sweating (improved after time but remained) -Delayed ejaculation (improved after time but remained) -Hand shaking (occasionally) -Excessive Hangover in the morning after drinking alcohol during night Despite its side effects, I find cymbalta the best choice for Depression, Anhedonia and Insomnia due to GAD. My GAD controlled my life since I couldn't handle any stressful situation but thanks to duloxetine I can have a normal life again I enjoy playing videogames/watching movies again. I can go out with friends again without suffering extreme anxiety I can sleep at night easily and naturally Overall it's a very good drug. It only takes 1-2 weeks to work By the way, if you want to quit this med there is only one way: Opening pills and removing a few micro-capsules every 2 weeks (let's say 20 micro-capsules). You won't even notice M 27 6 months
60 MG 1X day
6/25/2012
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 2  GAD Weight loss and increased anxiety I stayed on cymbalta longer than I should. It did nothing for my GAD and actually made it worse. I only stayed on the medicine because it helped me lose weight. Unlike others - I had no problem getting off. I went from 60 to 30 to 0 with no side effects at all. M 35 1 years
60 1X day
6/25/2012
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