CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Depression, OCD A few days after taking cymbalta I experiened a little bit of nausea. Side effects have gone away after 4 weeks. Cymbalta is a great medication for depression. If you have not taken anything for depression, this drug can help you. It helped me and now I love life and I am living like I could never live before. I look back now and think, "That was me" I do not have obsession like I did from OCD and now I am happy and stress free all the time. I can't say enough positives about this drug, it is amazing. Cymbalta, you rock. 5 weeks
6/7/2006
 5  depression As a psych.; amazing and immediate recovery from depression but I agree with many here that you sacrifice sleep and in my case, rapid weight gain. Once you are stabilized, it's most important to get counseling. The most effective treatment is still cognitive behavioral. F 45 1.5 years
6/4/2006
 3  depression I definatly get real nausious. I am having strong flu like symtoms but I am coming off of effexor and that has always been hardcore. I have been on effexor for 11 years and it has help me funtion and provide for my family, but I have been really tired and have to contantly fight weight gain. I have noticed that I have a little more energy and more mental clarity in the short time that I have been on Cymbalta. I'm going to stick it out and give this new drug several months before making a decision. God bless M 35 11 days
6/3/2006
 1  Fibromyalgia Violent vomiting, extreme headache, extreme worsening of RLS symptoms. That was after 1 30 mg dose. The vomiting lasted a day - I did not sleep for 2 days due to RLS and PLMD becoming severe. When I tried to sleep, I woke up with several bruises. I'd about rather just die than take this again. I think that severe RLS/PLMD sufferers should avoid this. F 38 1 days
6/3/2006
 2  chronic facial pain Gesichtsschmerz loss of concentration, irregular sleep, sweating in sleep, trembling fingers, hair loss, different sense of taste, less appetite, less intense feelings The medicine didn't make the pain any better, though I'm taking 120 mg/d for two month now. I think I will stop taking Cymbalta, as it affects my studies at university. Since I'm on the high dosage I have severe problems thinking clearly and remembering things. I cant't say much about the effects of Cymbalta in treatment of depression, but I wouldn't recommend it for treatment of headache/facial pain. F 26 6 months
6/2/2006
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 1  anxiety/depression insomnia, EXTREME nausea,sensations where it felt like someone was pinching or burning me, severe heart palpitations, sharp pains in my head, AND MANY MORE My doctor told me this was a wonderful drug, so i thought i would give it a try, from the first day my symptoms started and only worstened or increased, Had to go to the emergency room because i felt like i was gonna die, this is a VERY SCARY drug and i suggest you do alot of research to see if it is right for you, honestly i don't suggest this drug to anyone, i threw 130 dollars worth of this medicine in the garbage because it made me feel that terrible. F 21 2 weeks
6/2/2006
 1  fibromyalgia NIGHTMARES! and some marked drowsiness. I would NOT recommend this med to anyone. Too many side effects. F 25 5 days
6/2/2006
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 4  pelvic pain/vulvodynia Started off with a smaller dose then increased and had minimal side effects except for sweating at night, even when i'm cold. I noticed that if I forget to take the drug, even for one day, I will get very dizzy. Seems to be helping; pain is less intense and I feel better about the prospect of it eventually going away. F 34 4 months
5/30/2006
 2  Migraines Constipation Restless sleep Found no change in having migraines when taking this medication, but did have a weight gain. F 51 5 months
5/29/2006
 5  severe leg pain from nerve damage Constipation. Within the first few days of taking this medication I felt like my heart was going to explode. I went and checked my blood pressure and it was the highest it's ever been in my life and I have never had high blood pressure. I went into a state of panic that lasted nearly 15 hours. This is a scary scary drug, and it made me severly suicidal (never had depression or thoughts of suicide)! Watch out! It completely took away my leg pain but the side effects are just unbareable. There is something wrong with this drug. F 22 10 days
5/26/2006
 1  FMS, neck pain, fatigue Tired, dizzy, concentration problems, depression with suicidal idealation (all I did was think about ways to kill myself), feelings of worthlessness But on the plus side I didn't have to pee as often as normal. Made the fatigue worse and because I was more tired than before I had a harder time dealing with the general FMS pain and neck pain. I don't think it made the pain worse, but it certainly didn't help it. I was so tired I kept thinking I was not doing anyone any good and I should just kill myself. So I stopped taking it (about 8 months ago) and I'm, well, more alert than I was while I was on it. I can't remember the last time I cried and I cried almost daily while taking this medicine. I also almost can't even understand how or why I wanted to kill myself while on this medicine. I guess it did affect my brain chemicals, but in a rellly BAD way. I would say NOT to take this for any reason other than you are ALREADY depressed! F 34 3 months
5/26/2006
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 1  Depresion and anxiety Jitters, exessive sweating, horrible headaches, irrational thoughts of committing suicide. It instantly relieved the physical pain in my shoulders and back caused by anxiety for the first 3 months, but the side effects were too much to handle. F 24 6 months
5/26/2006
 5  depression constipation F 64 4 months
5/25/2006
 5  Depression Mild dizziness first 3 days. Very minimal side effects. Worked very quickly with minimal side effects. Really nice! F 38 3 weeks
5/25/2006
 5  Depression, Anxiety Nothing that stands out! It did not increase my appetite or make me sick to my stomach. Fortunately, I have not experienced side effects on this medicine. This is rare, for I'm usually very sensitive. I love this medicine! In the past, I have tried prozac, zoloft, and wellbutrin sr. I have mild depression that had gotten worse since I had an abortion and relationship problems earlier this year. Well, I now feel better than I have in a looooooonnnnnnnngggggg time. Wow! This medicine is not a cure-all, but it definitely helped me get back on track and feel better! I'm my usual goofball self again! F 26 2 months
5/24/2006
 4  IBS Felt really strange when starting Cymbaltia. Had major withdrawal when I stopped. Took for a year and it seemed to cure my IBS. M 34 1 weeks
5/24/2006
 5  Major Depressive Disorder Flu-like symptoms, dizziness, headaches, stomach problems that lasted on week before going away. Loss of apetite, occassional blurred vision, sweaty hands. I have been on medication for ten years, and Cymbalta is the first one to work. I finally have the chance to be myself without depression again! My advice is to try to stick out the side effects if you can. The majority of mine have gone away. I wouldn't give up this medication for anything. I went from suicidal to outgoing and cheerful within a matter of months. It really has saved my life. F 24 3 months
5/22/2006
 4  Fibromyalga and depression Night Sweats, lack of concentration and spacy feeling-living up to the dumb blonde sterotype Since starting it 2 years ago I have left my husband of 20 years. I definitley have an "I don't care" attitude and things that used to be important to me simply don't matter anymore. I'm scared to go off of it because it helps my muscle pain so much-I don't want to go back to lying in bed all day. F 47 2 years
5/22/2006
 5  Depression Wonderful Weight Loss 25kg in a year I cannot miss a dose as I get a tingling feeling in my head. It is great I have tried many over the last few years. The last one was Efexor and I put on a huge amount of weight. With Cymbalta I easily returned to my normal weight. I have energy and confidence that I did not have before. I take 120mg F 42 1 years
5/19/2006
 5  Depression Since I was taking other medication before so no side effects were obvious. I have been taking cymbalta for a few years. Previously I had taken lexapro, welbutrin and klonopin. My doctor has prescribed different dosages of cymbalta and the present 60mg has seemed to be the best. I had lost the abililty to concentrate and was actually afraid to even drive. Now I have much more confidence and enjoy things I had given up on. I am now able to read an instruction manuel with no problem and operate my computer and camera with ease. This medicine is a real blessing to me. emails are welcome. M 74 24 months
5/18/2006

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