CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2744 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Depression After the third day on 30 mg of this drug I felt like I was in a fog. I was completely depleted of all energy. It kept me up all night and I would sleep all day. The first couple days are hard for me to even remember what went on. I do not recommend this medication. Feeling this out of control is scary. F 39 10 days
11/26/2007
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 4   depression and anxiety Only thing i have noticed is the constipation, otherwise nothing else. Been taking paxil for about 5 years and was not satisfied with the results. made the transaction from paxil to cymbalta without a hitch.Getting away from paxil also improved my sex life. M 54 11 months
11/25/2007
 4  Bi-Polar, depression very tired..head fog. went from effexor to cymbalta. felt tingling for the first 5 days. I have been on it for 2 weeks and I have finally seen the light. I have been feeling really good. Mood is great. but I can tell when it is time to take it I get this tingling feeling,like when I turn my head my brain is a bit behind....but other than that its been good to feel like life is worth living again. F 45 14 days
11/24/2007
 2  Depression/anxity After 3 days my tongue was triple in size and a dark maroon color vivid dreams weird and wild,sores on tongue,no crying,head aches were gone. I liked that it made me seem emotionally detached events happened that would normally make me burst into tears but with Cymbalta I was emotionally free.I had less headaches I hate that I had a reaction to it and my doctor took me off of it. F 42 30 days
11/24/2007
 5  GAD and depression none M 57 30 days
11/23/2007
 3  mild depression difficulty sleeping, sweating all hours of the day, no sex drive at all, decreased appetite, does not do well with alcohol, get extreme headaches with two drinks, mentally in a fog...sometimes I think I'd be better off depressed..... M 54 40 days
11/23/2007
 5  Depression & anxiety Tummy hurt for the first day but none since then. When my doc first recommended Cymbalta I read a lot of mixed reviews, most coming from this site. I was terrified to try it but basically at the end of my rope. My depression and anxiety were making life hell for both my husband and me, and after trying or being on several anti-depressants in the past, I decided to give Cymbalta a try DESPITE the reviews I read. I first took 30 mg and felt better but began having side effects (no orgasm). Doc decreased dosage to 20 mg a day and it has changed my life! I am finally back to ME, the real me, 100%. Absolutely no depression, no anxiety, no panic attacks. I went from being a pessimist to an optimist in two weeks. My husband and I haven't had an argument since I started taking it. I feel great! Just 20 mg has made such a difference in my life I felt I needed to come back onto this board and share my story. Any time someone comments on how I've changed, I'm never shy to say, "Thanks Cymbalta!" It's great to be happy and l F 37 7 months
11/22/2007
 1  depression weight gain i gained so much weight F 38 1 years
11/19/2007
 3  neuropathy Weight gain, hungry all the time especially craved sugar at night. I noticed a difference in my pain it took the edge off and actually noticed that my mood was very even and I felt very content, but I gained 8lbs within 1 month after maintaining my weight for 9 years. So it was a catch 22 because I was getting depressed about my weight gain. I stopped taking it 8 days ago and my cravings have subsided and I'm starting to loose weight. F 30 2 months
11/18/2007
 1  Depression Weight Gain - 60 pounds in two years; loss of interest in sex; no desire to particpate in life; stronger feelings of worthlessness I've been weening off Cymbalta for a month now. I'm doing my own taper program to reduce the withdrawl effects, especially the brain zaps. Been a little bit*hy, but only when I get over tired. I don't crave seratonin producing foods as much any more and weight gain has stopped! I'm starting to get interested in my life again... I think doctors need to research this drug more than just relying on what the pharama companies tell them in order to sell it. F 44 2 years
11/17/2007
 3  depression,anxiety,severe pain nausea mostly, some headaches I have tried every drug in the book, either Im allergic or makes things worse. So far nausea is my worst side effect, and some drowsiness. Maybe will take at night. HOWEVER Im only on my 3rd day and have done some sleep walking and eating in my sleep. Not sure what that is about but didnt do it last night. I sleep pretty good on it so far. And Im a very poor sleeper! Those of you that have only been taking the drug less that a week or two should give it a chance, it usually takes drugs a couple weeks to level out in your system. But to each his own. Im going to try as long as I can. If this can help me I will be excited. F 45 3 days
11/15/2007
 5  Depression and hypomania. Bi-polar Tired, wich could come from my depression. I hade a depression and was on SSRI and Lithium when I suddenly got hypomanic. My MD changed the SSRI and started me on cymbalta and increased xanor. It took me 5-6 days to come down from my hypomania. This is an observation from someone who only used the medicin one week. F 43 7 days
11/14/2007
 2  Depression,anxiety Constipation,tremors and brain zaps on day 10 after changing a dose to 60 mg. I had to switch to Cymbalta after using Lexapro for 8 weeks. I had to get off both them for the same reason: nightly tremors. Since I had convulsions when I was a child I didn't want trigger it back. Otherwise both medications are tolerable and gave me a lots of energy and positive change in life. F 39 10 days
11/12/2007
 2  Fibromyalgia Severe indigestion, and I cannot sleep at all! The insomnia is so bad, I may go crazy soon. I really don't think it is doing anything to help my fibro, and the indigestion is so bad i cannot stand it anymore. I am just going to stop taking it. I have only been on it for a week and a half and I can't take it anymore. F 32 10 days
11/12/2007
 4  Major depression The med simply worked. I took three weeks to get to 60 MG, stayed on it three months and then took three weeks at a reduced rate to exit. The only reason I came off was "noise" in my head similar to an electric arc from a welding machine. Is this what others are calling "Brain Zaps"? Ren M 71 4 months
11/11/2007
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 5  anxiety/depression weight loss, insomnia (all went away after two weeks) I have tried about fiver other anit-depressants and they all made me CRAZY. I couldn't handle the side effects. After just a couple of days on 30mg of Cymbalta I notice a difference. I felt human again, although I had to reduce dosage to 20mg. I had trouble sleeping but not with the 20mg. My doctor told me I can even open the pill and split the 20mg in half which I'm cosnidering. I haven't had a single panic or anxiety attack or bouts with deperession in over a month since taking it. It is a life saver for me. F 43 2 months
11/9/2007
 5  anxiety Initially because I was very anxious before my treatment started it made me feel extremely anxious for 7-8 days. But I am so glad I stuck it out because I am now calm and feel "normal" for the first time in a long time. F 45 64 days
11/9/2007
 2  Depression, Anxiety Increased agression, nausea, diarreah, nightmares(extreme and vivid), increased craving for sweets and carbs, profuse sweating not related to anxiety. This medication was not a good choice for me. Although this drug has the reputation for being "weight neutral", unfortunately, that wasn't the case for me. I also found it to pack less of a punch in terms of effectiveness than Zoloft. The side effects were enough to make me discontinue the medication. F 37 3 months
11/9/2007
 5  Chronic Depression, OCD, Anxiety The first week I had flu-like symptoms and felt somewhat detached from myself. Symptoms improved each day. I have tried them all. This medicine is a blessing for me. It's the best I have felt since grade school. I am enjoying life again. I have energy and motivation. Since I have chronic depression, I will not go off EVER! I'm ok with that since I feel so good. F 39 2 years
11/8/2007
 3  Pain/Nerve Damage Weight Loss (40lbs.). Loss of appetite. Abdominal pain. Diariaha. Headaches. Dizziness. Nausa. Very recluse. No social life. Pain/Nerve damage symptoms reduced. Very calm/mello. M 49 2 months
11/8/2007

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