CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Depression/Anxiety/ Pain Started Med, now cannot get off it because of withdrawals. F 44 1 years
20 1X day
12/20/2020
 4  Anxiety and mild depression None, except maybe slight hunger, but I already had increased appetite so can't say for sure. I had tried a higher dose of this before and found it made me feel a bit odd. 30 mg seems effective for me w/o side effects and I think it helps with my chronic pain from damaged nerves also. F 56 1 years
30 mg 1X day
12/11/2020
 1  depression It has caused me chronic yeast that has went systemic and destroyed my gi tract. The worst part of it all is the withdrawals trying to get off it. I have been weening 5 years down to 4.5mg from 180. What a nightmare!! The worst drug ever made. You have been warned. Stay away from snri's my doctor said she has difficulty getting patient's off them. F 33 8 years
180 1X day
11/29/2020
 1  Nerve pain Horrible nausea, groggy fogggy feeling, upset stomach, tiredness. Made my anxiety way worse. My whole body was shaking. Just took one pill. Never will i take it again It feels like the flu. I hope it goes away soon. I keep taking gravol all day . I am so upset F 37 1 days
30mg 1X day
11/28/2020
 1  Supposed depression Suicidal thought, more depression Going off it!!! F 55 0 days
60
11/16/2020
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 1  Anxiety Extreme flu-like symptoms. Extreme! It's been 3 days since I took my one and only dose and I'm still very nauseated. I missed two days of work because of it. I had no idea a medication could do this to a person. Never, ever again. F 35 1 days
30mg 1X day
10/30/2020
 1  Fibromyalgia and back problems Taking it was ok coming off of it was sheer hell. Every time I turned my eyes had this weird static noise in my ears, vomiting,shaking,dizzy palpitations just hideous. It should be taken off the shelf so many legal cases against the people who produce this F 41 100 days
90mg 1X day
10/28/2020
 1  pinched nerve pain omg awful took with tramadol high bp dizzy fast heart rate blurry bision for 2 and a half days Should be banned do not take not worth it. F 62 6 days
20 mg 1X day
10/18/2020
 5  Chronic Muscle/Skeletal Pain No side effects This is unbelievably effective for my chronic pain of 25+ years. After trying everything (NSAIDs, Opioids, Plaquenil, Prozac, Amiltriptaline, Gabapentin and no relief, I'm nearly in disbelief that I have zero pain most nights, sleep better, and can participate in most activities. Honestly, it's like a life saver! My pain was constant, intense and debilitating - and it's basically gone. Cymbalta began working for me right away. By the time I upped to the 60 mg dose after 2 weeks at 30 mg - I was lying in bed at night amazed at not feeling pain. F 55 6 months
60 1X day
10/11/2020
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 4  Fibromylagia Moderate Side effects first 2-4 weeks. Afterwards, feeling great. Helped with pain, energy level, cured my IBS and overall i feel much much better. Now after 3 months i feel as if it doesn't work so Well as it did after 4 weeks. F 40 3 months
60mg 1X day
10/9/2020
 5  anxiety it turned my anxiety into depression it has less of an effect on libido and when mixed with alcohol than SSRIs F 21 2 years
30mg 1X day
9/29/2020
 4  Depression, anger and anxiety 3 days of feeling nauseous, tired and depersonalized followed by improvement on the 4th day and feeling like my old self after that. Working wonderfully for the conditions prescribed for. I was afraid of taking this or any other antidepressants, this is my first experience with any such medication. M 47 8 days
20 1X day
9/27/2020
 1  Depression and Pain Nausea, diarrhea, dilated pupils, but the worst side effect was insomnia. The first night I slept three hours then was wide awake, and every night after, the sleep was less and less until it was none. The part that scared me the most was I did not feel tired. In fact, I felt nothing. It got rid of my sadness along with feeling any emotions at all. I lost interest in everything and had zero motivation. I am on the second day of no Cymbalta now. I was finally able to sleep four hours today. I am thankful for no withdrawal problems yet. F 42 7 days
30 mg 1X day
9/25/2020
 2  Anxiety, depression Brain fog constantly, gag reflex, very tired but can't sleep F 41 3 months
20 1X day
8/30/2020
 5  Fibromyalgia and Anxiety Dry throat (drink more water as solution), dizziness if you stand up too fast, nausea for the first few months but it’s fine now. Weight gain. I started taking cymbalta for my fibro in grade 9 when I had resigned myself to living a half life, essentially. Within the first few months of taking it I noticed change in my energy, fatigue and energy levels for the good. I’m able to live life now. F 16 3 years
60 MG 1X day
8/27/2020
 1  Depresson anger I dont like throwing up Also mulyi bowel dirrea Terribly I do not like F 56 5 weeks
3o mg 5X H
8/15/2020
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 1  Depression and Anxiety I completely lost any amount of libido that i may have had left on this drug, and 1 month after discontinuation the issues still persist. I gained 20 lbs on top of the 15 i gained on effexor. I also had night sweats, which were more severe on the effexor but continued moderately with the cymbalta. I went immediately from cymbalta to wellbutrin with no weaning and did not notice any severe withdrawal symptoms, but i was sick and extremely depressed for the first 2 or 3 weeks after discontinuing. However, i was also withdrawing from an herbal drug and beginning the wellbutrin at the same time so it is impossible to know which, or if all, of these factors were affecting this. Overall, i am 100 times worse after both antidepressants than i ever was before them. I was harmed much more than i was helped. F 21 7 months
90 mg 1X day
8/15/2020
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 1  Panic an anxiety attacks When I went to see my doctor about anxiety an panic attacks I was not depressed at all. My doctor decided to put me on Cymbalta said that depression and anxiety go together and then that we could try this medicine. With my Cymbalta they added Xanax I started taking Cymbalta and it seemed to help because I couldn't feel anything it was almost like I was numb to the anxiety and the panic attacks. I thought that was a good thing until I started not caring about things that I should have been caring about. I tried five times to come off of Cymbalta but always went right back on it because of the side effects coming off of it was so hard. I finally said I didn't want to go through this stuff anymore. I didn't want to not care and not feel. I have a 13 year old daughter and for the past 11 years I have not care about anything, before I got on the Cymbalta I was happy with my child and my life it was only the panic attacks I didn't like, after being on the Cymbalta I become very depressed and did not want to do anything .I knew that it was the Cymbalta that it was making me feel this way so I started weaning myself off by taking the beats out of the capsules. I'm down to 20 mg now and I'm going to go down to 10 and then 5 and I hope to be off this medicine .I feel like this medicine has robbed me of my life of 11 years. I would not recommend this medicine to anybody. F 33 11 years
90 1X day
8/3/2020
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 3  Depression/anxiety I gained 40 pounds in 6 months, and my blood pressure increased. I was already in a low calorie diet before starting cymbalta 1250 calories per day so I was advised against eating less. I was already working out 5 times a week before I started the drug. -- It worked GREAT for my anxiety and depression, but the extreme weight gain was making me hate myself and backfired. After talking with my psychiatrist about this, we decided to wean myself off cymbalta. I am working with a nutritionist, and still gain weight the few weaks AFTER I stopped the medicine. Cymbalta did something to my metabolism ..... F 55 6 months
60 mg 1X day
7/12/2020
Email
 5  Depression, anxiety This drug changed my life. I'm more relaxed and optimistic for the first time. I wish I'd tried medication a decade ago. My partner noticed the change, and even my dog seems happier around me. At first I had trouble concentrating and extreme exhaustion, but I switched to taking it at night and now I sleep really well and feel well-rested and positive in the morning. Keep in mind lots of people only come on here because they're having the negative side effects, probably most people dont bother to rate who are satisfied with it. I was scared to take any meds at first especially after reading negative reviews - so just know it can help!! F 32 2 months
60 mg 1X day
7/6/2020

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