CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  depression F 36 4 months
6/20/2007
 5  depression and OCD VERy very slight twtch in my hand or arm sometimes. Does not happen much and is not noticable. I was very depresed and suicidal. I was on other medications but found that Cymbalta works better that anything I have taken. and it has proven to keep me stable. I have been on it for a year now. F 44 1 years
6/19/2007
 3  OCD Head aches, sleep, seats, all of the above I just felt like poop. I read this web site 1 day and most of the stuff I read was just the same like the weird dreams and sweats. I felt very tired went to bed feel right to sleep just to wake up in a sweat like a pig. Froze everyone at work I think they were beging to hate me. I am now on a lower dose from 60 to 30 and can already feel the difference. I hate this drug.. Cymbalta started out great for me even recommended it to people but boy am I sorry i was like a sweating zombie.. F 40 2 years
6/17/2007
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 2  Anxiety/Depression Memory loss,Disoriented,Sluggish,Short attention span,Muscle pain,And short temper Started out great.After three weeks it changed my personality for the worse!! M 30 100 days
6/16/2007
 4  Depression, Social Anxiety, ADD Nausea, headache, loss of appetite, racing thoughts, increased social anxiety. I've been treated for major depression and anxiety for about 2 years now. I took Zoloft and Xanax for about 6 months, but the combination made me feel like Frankenstein. Since taking Cymbalta, my depression has gotten a lot better, buy my anxiety got A LOT worse. After 3 weeks, I had to start taking Xanax again to be able to leave home without crying. For the first month, I took Cymbalta in the morning because the doctor said it would make me wired. It actually made me really tired. Over the weekends, all I did was sleep. Now I take it when I get home from work, and although I don't sleep straight through the whole night, I have a lot more energy during the day. The combination of the Cymbalta and Xanax helps me be more relaxed and productive at work and at home. F 28 6 weeks
6/13/2007
 5  depression, anxiety, pain mild nausea and stomach upset, mild headache I have suffered severe pain, numbness and tingling in my left arm, severe pain in my left leg for more than 5 years. Nothing else has ever relieved it. After 2 weeks on this drug, the pain is gone. I am also free of anxiety and my depression is lifting. I'm like a new person. Thank God for Cymbalta! F 55 14 days
6/12/2007
 5  for fibromyalgia none has helped me immemsely with pain F 62 18 months
6/12/2007
 1  Borderline Personality Disorder Oh geez...where do I begin. I RARELY sleep; when I do, I wake up constantly. Unbearable body tremors, diarrhea 24/7, have lost 25 pounds and look basically anorexic. Can't concentrate for more than a few moments, without losing interest. Can't stand for more than 5 minutes tops. Horrible nausea that only gets worse at night. Dizzy constantly and sharp shooting pains throughout my body, all the way to my head. The worst part is the TWITCHING. I feel like I'm getting Tardive Dyskenesia. Have problems peeing also. I have been on this for about 5 weeks, and my condition is worsening with each passing minute. I'm deteriorating; slowly but surely. I'm 15, and have been tried on every anti-psychotic and anti-depressant on the market. Nothing works, but at least they didn't drive me insane like CYMBALTA. I suggest if this is your problem, check out holistic doctors. Thats what I'm doing now. F 15 5 weeks
6/11/2007
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 3  Depression My Dad passed away in 05. My Mom has not been able to deal with this after her 57 years of marrage. She has been taking various anti depressents. Celxa was the last one. Her dosage was increased to 40 mg and she got tremors and increased anxiety. Her MD put her on cymbalta. She has been taking it for 2 weeks. What I have noticed as her daughter and care giver is aggression. Normally even withourt drugs she is very passive. If I would call her to see if she wanted to come for dinner she would say yes no matter what time it was. Now her answer was your calling at 5 and want me for dinner I just made a sandwich. I thought it was great she had an opinion my husband took offense. The other thing where I thought she was out of character was that she was mad at a very good friend who she normally wouldn't be. She seems to be taking a stand and being angry where she normally even with out medication she is very passive and going along with the flow. I will say she isn't crying as much. F 76 10 days
6/10/2007
 2  Depression, chronic nerve pain dizzyness, palpatations, speediness, no appetite, diarheah, interrupted sleep (no dreams) Day 1 was bad - had problems breathing, forgetting to breathe and dizziness. Very 'electric' feeling. Day 2 was a bit better, noticed no depression and minimal nerve pain! But by the end of the day I was literrally pulling hair out of my scalp from itching. I took 30mg caps... I think I may ask for a much lower dose to start with. F 45 2 days
6/10/2007
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 2  depression / anxiety / chronic pain dilated pupils, blurred vision, nausea, irritable, tired, but very jittery and uneasy, so I can't sleep. Ravenously hungry, but nothing tastes right so I can't eat. Dizzy,confusion, agitation, extremely dry mouth, clenching jaw all day, unable to stop, uncontrollable muscle spasm. I took it for the first time last night, and today has been the worst day of my life. The side effects are so bad I don't know if I can keep taking it to get through the initial stages. I can't do anything, standing up for more than a few minutes makes me dizzy, and I'm so tired, but can't sleep. Does anyone have any ideas? if so, feel free to email me. I'm sure that it's not a bad drug, and someone else stated, if you had problems with it, you're more likely to tell someone that if it was great, but it seems like the patient informationthat the company puts out isn't accurate...only 4% of people have any adverse side effects according to them...so all 4 % of us managed to find this site? F 26 1 days
6/10/2007
Email
 4  Depression & Pain for CTS Oh it helped and was nice for the depression. Felt like a new person after 7 weeks but I only had minor depression (SADD) I took it at the time i was diagnosed with Carpal Tunnel It helped that so much. Gained 12lbs in 30 days after 7 months out of no where. Dosed down from 60 to 30 for 3 weeks. Today is day 4 off it and I HATE IT. The withdrawls make you forget all the good I took it for 8 months for depression initially. It turned out to help my carpal tunnel. Once I got over my seasonal depression, which by the way I was a whole new person on it after 7 weeks. I wasnt willing to give cymbalta up because of the help with my hand, until someone turned me on to B-6. I am writing because I decided to dose down, what I thought was dosing down slowly. They had me on 30 mg to start for two weeks then 60mg there after. I went to 30 mg for three almost four weeks. I went off completley this past Tuesday. Everything they say on the forums about the hellish withdrawls are true. The ones that say they dosed down even slower and lower dosages have the same problems. Just a little note of your not the only one. I didnt think I would ever want to get off of it either but I did. Now I am wondering what in the heck I was thinking. Oh it might have been the 13lbs i gained out of no where in less than 30 days before i started the dose down. The withdrawal sympto F 37 8 months
6/9/2007
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 4  ANXIETY SLEEPINESS DURING THE DAY & FEEL OUT OF IT ALOT,SWEATING,SOME INSOMNIA AT NIGHT ONLY,WEIGHT GAIN ABOUT 40LBS IN A FEW SHORT MONTHS,CRAVE SWEETS LIKE A DRUG,CAN'T SEEM TO GET ENOUGH,ALSO HAVE TREMORS WHEN I WAKE UP IN THE MORNINGS OR AFTER TAKING A NAP..VERY THIRSTY ALL THE TIME,SOMEWHAT CONSTIPATED TOO,BUT OTHER THEN THOSE SYMPTOMS I'M GENERALY HAPPY ALL THE TIME AND I NEVER HAVE PANIC ATTACKS...I THINK THE DRUG IS A GOOD THING. I AM A LITTLE WORRIED ABOUT TRYING TO GET OFF THIS DRUG ONE DAY, EVERYONE SEEMS TO SAY THE SAMETHING ABOUT IT BEING HELL TO GET OFF..AND THE FACT THAT IT CAN CAUSE LIVER DAMAGE,AND ITS INCREASED IF YOU HAVE A BEER EVERY ONCE IN AWHILE... F 42 2 years
6/8/2007
 1  pain and numbness in leg(s) Was taking 30 mg once a day. A definite decrease in sexual drive (thought i was coming down with Erectile Dysfunction). Much fatigue and some confusion. This drug had absolutely no effect on my pain whatsoever. If anything, it added more problems. New doctor suggested taking 60 mg a day for pain and gave me samples (as my coverage went sky-high on "brand-name drugs). I did not mention the lack of sexual drive because I wasn't sure if it WAS from Cymbalta. I had been weening myself off this drug when I went to her, and my sex drive IS improving. I have not yet started the 60 mg a day and hesitate to do so. I will have to tell her on my next appointment. Meanwhile, I try not to stand or walk too long to avoid the pain. M 58 2 years
6/8/2007
 5  Drop Foot,chronic back and leg pain none Cymbalta replaced Nurontin due to nite leg pain and chronic back pain,its wonderful. Ive been disabled 17 years and this drug is a God Send I take it in conjunction with Duragesic. M 49 1.5 years
6/7/2007
 1  chronic depression brain zaps - horrid, uncontrollable twitching of lower lip, contant ear ringing, extreme light & noise sensitivity, sleeplessness, crying for no reason Everyone who is contemplating being placed on this medication should first be warned of the side effects, & especially the withdrawal effects. F 48 6 months
6/7/2007
Email
 5  Anxiety/Depression/Bi-polar - None - I have been on Cymbalta for two day's and have had no side effects. I feel great! I can say that this medicine really works effectivly and fast. Unlike other meds that I have taken in the past (and trust me, I have taken more then you can image) I felt it working within and hour or two after taking the pill. My doctor has me on 30mg for one week and then 60mg from there on. Last night I slept GREAT! I didn't wake up nor have night sweats. This morning when I woke up for work I was in a great mode and that is unusual for me. Two day's ago I was reading all of your comments aboout the side effect to Cymbalata and I was really scared and almost didn't fill the prescriptiong but then thought to myself, I have been in more pain then this so what the hell and give it a try because everyone is different and I am sure it has done more good then bad. Everyone needs to keep in mind that you are going to hear more form people who have a complaint about something then the people who don't. F 28 2 days
6/5/2007
 5  depression/anxiety Dry mouth...sleepy...and those arent to bad. Took a while to work i have been on alot of different ssri's and cymbalta is by far working the best. I have been on 60 mg for about 2 months now and im feeling a whole lot better. My anxiety has decreased and i am in an overall better mood! It took awhile to work and to be able to feel the positive affects...but hang in there and get through the first couple of months M 21 2 months
6/3/2007
 4  Severe Depression Complete loss of sex drive; nightmares if I miss one tablet together with electric shock sensation M 35 450 days
6/3/2007
 3  Chronic back pain Extreme tiredness, blurred vision, constipation, weight gain, and irritability. My neurologist suggested Cymbalta for chronic back pain. Started with ten mg's and increased to 20 mg. While there has been some pain relief the side effects are more than I care to deal with. I am planning on asking him to take me off of Cymbalta and increase my Tegretol. F 42 3 months
6/3/2007

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