CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Fibromyalgia Feeling drowsy all day. No energy. Even with the pain I manage to get up & do my daily routines. Felt horrible. Plus got these ugly cold sores in & outside my lip. Woke up with painful swollen lip after my second day...pain was bad so I was willing to try anything. Big mistake...can't drink or eat anything now. Can barely talk. F 33 2 days
30mg
11/21/2011
 4  Depression and Musculoskeletal pain Constipation, lucid dreams, apathy (which is better sometimes than worrying about everything) F 43 1 years
30mg
11/20/2011
 4  Depression If I miss just one day I feel dizzy. It has been a tremendous help for depression, anxiety, and mood swings. F 40 1 days
60mg 1X day
11/19/2011
 4  Depression muscle and joint pain I have no horrible side effects from this med. My apologies to anyone who might be offended by the following. I obtain an erection and orgasm much more slowly than before. My muscle and joint pain is almost totally gone. What depression I had has reduced alot. Situational anxiety has decreased substantially. M 51 1 months
30mg 1X day
11/17/2011
 1  Dysthymia, GAD, BPD apathy, weight gain, nausea, fatigue, anger, irritability, twitching, worsening of anxiety, blurred vision, difficulty concentrating, suicidal idealisations I have been on about 7 different antidepressants. This one, other than Effexor, I have found to be the worst. Lately I have been really angry, irritable and unable to keep these feelings to myself so they have been affecting my relationships and work life. I constantly have suicidal thoughts and my self harming worsened on these drugs. If I forgot to take a dose I would get severe brain zaps, ringing ears, nausea and really irritable. I don't feel like I am myself; like I'm a different person with a different personality. I finally convinced my doctor to switch me over to Avanza. I wouldn't reccommend this drug to anyone, but as antidepressants are, it can be different for everyone and it takes time to find the right one (which I'm not sure exists for me). F 22 2 years
60MG 1X day
11/16/2011
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 1  depression I should have known after the first couple of days, I should have discontinued taking this horrible drug immediately. Ridiculous brain zaps, involuntary muscle movements, and eyes that looked like they were bulging out of my head. "Wow, you look completely freaked out", is what one of my closest friends said. But since I was desperate for relief from suicidal depression, I perservered. Within about a week, my eyes looked normal, but I still had blurred vision after being 20/20 my entire life. And I felt better, I guess if you call feeling completely emotionless better. Zombie. Robot. Gained 15 pounds practicly overnight. Absolutely awful. I would seriously rather be on suicide watch then be a fat, blurry eyed robot. So I quit. It's been over 4 months and my eyesight is apparantly altered for good, the weight won't come off, regardless of increased activity, and now I have these horrible rages that I will fly into on little notice, in addition to my depression. PLEASE, i F 42 30 days
120mg 1X day
11/12/2011
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 4  fibromyalia dry mouth I wasn't worried about cymbalta at all until I read this reviews. F 64 18 months
60 1X day
11/10/2011
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 1  Depression "Lightening storm" in my head like pings. If I was late on my dose the dizziness and electric shock sensation in my head had me convienced I was going to have a seizure. I was weaned off the drug for more and three months but it took nearly a year and a herbal regimine to get me back to normal. I even had thoughts of suicide...not to say that I was depressed and hopeless...I would just suddenly picture myself holding a gun and putting it in my mouth. It was horrible. This stuff needs to be taken off the market!! If it hadn't been for the herbals I took I don't know where I'd be. F 40 5 years
60mg 1X day
11/9/2011
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 4  anxiety nausea, diarrhea, stomach pain (temporary), lucid dreams, drowsiness (temporary) The dreams are the only side effect that persisted. It has helped me tremendously to cope with my anxiety. Any medication can be harmful...but so can the effects of anxiety and depression. You need to weigh the risks and benefits. Everyone reacts differently and this is not the first med I tried. F 32 3 months
30mg 1X day
11/7/2011
 2  lower back pain an anxity what a horrible experience, I am 23 years old .I have tried many medacations in my life an this Drug has some of the strangest effects ever . I took it for the first an last time . I was completly emotionless had deep convo with an ex which should have made me cry or feel sad in some way yet i was completly unaffectedand an felt nothing . I couldnt sleep till about 3 in the morning and to my surpise was bright an bushy taled at 6 30 smilieing super happy i didnt even know who i was felt like i was a robet .An extremely smart movtatived one who was super foucsed its about 1 pm now i refuse to take another dose althou i am frezzeing and have chills dry month and zero desire to eat . Honestly it may be a mircle drug happy helps you lose weight cuz u have zero need to eat.Your mind is so open to learning im just extremely scared that i will need it everyday . so good bye mircle drug just flushed a 2mos supply down the toliet F 23 1 days
60mg 1X day
10/31/2011
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 1  for pain i have chronic fatigue syndrome and i think i have fibro. having a lot of muscle pain. took cymbalta at 10:30 am. it's now 5 pm and i'm extremely, nauseas, tired, irritable and running to the bathroom. i will not take it again. M 70 1 days
1X day
10/29/2011
 1  depression Every side effect that came with cymbalta I had while taking it. If you haven't started it PLEASE don't! F 26 6 months
60 1X day
10/27/2011
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 1  Bipolar depression TOTAL FLAT EFFECT I was so absolutely flat I had no emotions WHATSOEVER. No feelings of depression, love, hate, anger, NOTHING. No sense of humor, no laughter, which still persists to this day 5 yrs later I can not laugh or smile. I see something funny and cognitively say "hey that was funny". But I can't laugh. I would love to be able to laugh. I did not care abt anything. I did not grieve for my fathers passing, I rationalized it that he was in terrible pain, when he was the most influential person in my life. M 60 2 months
Donremembe 2X day
10/24/2011
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 3  Depression Emotionally Numb, Aggression, No Concentration, No Motivation, Excessive Hunger, Weight Gain Starting was tough, 1st 2 weeks were morning doses. Yawning constantly, Moving eyes caused a sensation I can describe only as a brain shock. Yawns were almost climactic, felt like I had run a marathon. The shakes and nightmares were horrible. Night doses helped, except the sexual problems, keeping aroused was almost impossible. 6 Months: Things settled I thought 'I Love Cymbalta',Something finally worked. 12+ Months: Started to notice how I just 'Couldn't be bothered' to do so many things. I was a Gym Junkie, extremely fit and energetic. The desire to eat now rules me, I have gained so much weight and i cant stop. 2 Years: I have changed. Home life fine, wife and I doing great but I am getting horrible mood swings where I just snap, aggression kicks in and I make no sense. I don't hurt anyone other than myself, but I need to smash something and scream. I have no regard for my wife's feelings. This is NOT me, it is scaring me and is getting more frequent. My concentration is getting worse which is making my work suffer (software developer), I am so tried though mostly sleep well, I don't seem to care about anything and thinking things I shouldn't. Cymbalta? I think so, I always felt like I handed over a little bit of control when I started taking it and now I think it is taking more. It gripped me like no other drugs had, and I have been on many. I want off this drug and have made the appointment with my Dr to hopefully get this under way but I am terrified. M 32 2.5 years
60 MG 1X day
10/23/2011
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 3  Muscle pain in my neck. Headache's, dry mouth This drug will cause you to gain weight and keep it. I gained 20 lbs. and sometimes I'll only eat one regular meal a day, two at the most with no snacks. I'm going to wean myself off of this drug because of the cost. ($160 a month) This is a drug that you have to wean off slowly because of the withdraws (ringing in ears, and it makes you feel weird) M 44 5 years
60 1X day
10/22/2011
 2  suspected fibromyalgia headache, dizziness, loss of appetite, extreme fatigue, disorientation, muscle weekness, chills The NP I was seeing at the time suspected me to have fibromyalgia. I knew whatever it was it slowly developed into something awful. I had severe pain in all my joints, debilitating fatigue and mailaise, Raynaud's phenomenon, hair loss, sudden dizziness, muscle weakness, extremely tender hands and feet, you name it I was suffering from it. She decided to put me on cymbalta which was a big mistake for me. I took the small dose of 30mg at bedtime. I had no recollection of the next day. I slept through the night right after I took it and all day the next day and all night.. It seemed like the only thing I could remember was a bunch of ppl coming in my room to check on me at one time. It was just a memory flash and was extremely vague. I was later told that it was only my mother and my granny. When I was finally able to get up my body felt really strange. I had extreme body chills, I couldn't unclench my jaws hardly and I constanly felt the urge to yawn. Try doing that while clenching your jaws lol, It hurts. I came to find out 8months later that I do not have fibromyalgia.. I have Lupus. Cymbalta is definately not for lupus patients. As for fibromyalgia, cymbalta has been shown to be effective for 1:4 ppl. My mothers friend has fibro and cymbalta helped her but of course its not for everyone. F 26 1 days
30mg 1X day
10/20/2011
 3  depression weight gain , insomnia tired of pills M 43 60 days
30mg 1X day
10/19/2011
 1  I have fibromyalga chills, headache, eyeache, ears ringing, tremors, cold sweats, loose stool, fatigue, dizzie, confused i took cymbalta for 1day and I will never take it again, I woke up dizzy with a headache, cold and sweating, shivering, my stomach felt like I had a stomach virus, my hands were trembling, I felt like I was going through withdraws or hungover, I couldnt get out of bed until 4pm, they really should have studied this drug further.....now I understand why most insurance wont pay for it....it should have been called cymBADta! F 34 1 days
30 mg 1X day
10/14/2011
 5  Depression I have only been taking cymbalta for 3 weeks and I have noticed a major difference and things just keep getting better! I did experience some negative side effects when I first started taking the pill, but everyday things got better and better and side effects subsided after a week. A total life saver!!! F 26 3 weeks
30MG 1X day
10/13/2011
 4  depressiin/anxiety Starting out at 30mg I lost my appetite and it wasn't very effective. Doctor then upped my dose to 60mg. For about 2 weeks I lost my appetite again but eventually got it back. If I do not take my medicine at 730 in the morning I will not be able to sleep at all that night. When I do fall asleep I have very vivid dreams, a lot of them nightmares. I just want to put this out there for all the people taking this drug, it does not work miracles after the first day you take it, your body has to get use to the drug. Ill admit it can be difficult but if you work with your doctor you can find ways to make the medicine work. It is not "poison " and your totally ignorant to say such a thing, doctors go to school for a lengthy period of time and are doing whats in beat interest for their ppatients, with the exception of some doctors. Suggestion ; if your having dif difficulty with the drug then work with your doctor to fix it. No med like cymbalta will just work over night you need to give it time and make it work with you. 4 months later and I'm still working with it but I have used just about every single kind of medication and all have failed, this has worked best with me. Another thing, everyone is different, everyobrs bodied function different and medicine works differently on every person. Read the warning labels if your parinoid about side effects or try herbal remedies instead which help tremendously such as teas. Those who have suicidal thoughts and tendoncies on this drug should obviously talk to your doctor and get off immediately. I am 23 years old and its quite sad listening to people blame their doctors and medicine for lack of help and care. You need to do some work as well in changing your life around and getting better. F 23 4 months
6o 1X day
10/13/2011
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