CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  depression, anxiety flu like symptoms, disconnected with family, zombie like The feeling is horrible from this drug. I want to feel the way I did 4 days ago, and after only being on it for 4 days, I'm not taking it any more. I feel worse from the side affects then I did from my depression. I cannot beleive they put this drug out on the market to put people's minds in a zombie state. Wish I never took the first one. F 51 4 days
30 mg 1X day
5/1/2010
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 1  fybromyalgia Lightheaded, increased appetite even when felt full, "light switch" effect, where it felt like an electrical current would speed through my body, decreased urine output - I couldn't hardly go. Withdrawl increased light switch effect and was HORRIBLE!!! The withdrawl was terrible and I was told there were no withdrawl symptoms. I have talked with some people who like this med. It was terrible for me...BE CAUTIOUS...they can't even explain HOW it works. Look up the parent company and see how they triied to pull off a very similar drug that ended in a recall. F 35 3 weeks
30 1X day
5/1/2010
 3  Nerve Pain Fuzzy memory I ran out and missed ONE dose and was dizzy and felt stoned. I've just lowered to 20 mg. and hope to be off of it soon. F 47 10 months
30 mg 1X day
4/30/2010
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 4  Depression, Anxiety At first I did experience some insomnia and restlessness as well as loss of appetite. However I stuck it out and after about a week all the side effects started to stammer away. I now feel like my old self. I am smiling happy and excited about my life. The horrible panic attacks are gone and I am able to be rational and use my head. F 21 2 months
60 MG 1X day
4/29/2010
 1  Depression brought on by job loss I went to my doctor due to some mood issues brought on by the loss of my job. He recommended Cymbalta and said that this would "help me through the rough spot" and was temporary. I took my first (and only) dose at about 8pm. I noticed that I was a little more restless than normal. Prior to tonight, my sleep patterns have been good, body clock was fine. I tried to lay down about 10pm and tossed and turned as if I had too much caffeine. I got up and piddled on the computer and tried to go back to bed. I then noticed that I felt as if I was on a bad acid trip or something (I have never tried any elicit drugs in my life.) I began to shake, and feel pressure in my abdomen. The pressure has never eased, and now I am pacing and feeling very "trippy" for lack of a better term. I have never taken any type of depression meds in my life, I have never needed anything of the sort. I am convinced that I will never take this nor any other med of this type again due to this horrible feeling. My mind is racing and I feel as if I am on a roller coaster that will not stop. It has been nearly 9 hours and this has yet to relent! Your mileage may vary, but this is not for me! M 39 1 days
30 1X day
4/28/2010
 1  Depression This worked great on my depression. However I couldn't stop eating; especially sweets. I gained 30 lbs. in 7 months. But the side-effects coming off were worse: numbness and tingling in my arms and hands that never went away, nightmares, and shortness of breath. I don't know what to do about the side-effects that happened once I stopped taking it. The doctor didn't seem to have any answers. Any suggestions? F 48 7 months
30 MG 2X day
4/28/2010
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 3  pmdd insomnia; urinary retention/bladder and lower back pain; dizziness; forgetfulness; foggy brain; weight loss; poor appetite Have cyclical moderate depression, body pain and joint pain related to perimenopause and although it seemed to stave off the depression, it did nothing for body pain. Didn't mind the weight loss, but the urinary retention and bladder and back pain were very uncomfortable. Waking in the middle of the night and not being able to go back to sleep was big problem. Felt tired in morning and always late for work. Reason for getting off was mostly regarding high cost of medication - even with insurance. F 49 3 weeks
60 mg 1X day
4/27/2010
 3  cluster headaches Was on Effexor 150 for 3 years, so minimal, but more hunger, tired. Sweating is a real problem, and missed one dose and was dizzy, out of body. It does help the headaches, positive, but I feel dull and more lifeless. It will be like Effexor, or worse, to stop. These drugs with horrific withdrawal should not be prescribed. Pain abatement research, please. F 67 60 days
60 mg 1X day
4/25/2010
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 1  GAD PVC's, Urinary Retention PVC's gradually subsided but lasted for a couple months, also noticed I wasn't emptying my bladder completely. When I gradually came off, it felt as though I emptied my bladder for several days! Also, SWEATING....I'm off for several days and sweat at the slightest move. Would NEVER recommend. F 57 4 months
30 1X day
4/25/2010
 5  anxiety None that I noticed. I went through quite a few medications over the past 20 years or so and nothing really helped. Now I feel like my old self again. I have confidence. Stuff doesn't bother me like it did. M 57 6 months
60mg 1X day
4/23/2010
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 4  depression Didn't really notice any new side effects increased activity...yeah! not tired all the time, helped depression didn't want to rip peoples heads off. used in conjuntion with wellbutron F 59 2 years
30 mg 1X day
4/22/2010
 1  Fibromyalgia Constipation, knotted stomach, weight gain, feeling like a zoombie, daytime sleepiness. I have tried to go off of this drug now for the 2nd time and I have dizziness and feel like I am going to faint. Afraid to go out or drive. I'm going to stick to it this time and quit this drug if it kills me. I would not recommend anyone getting started on this drug. Why do doctors give this drug to patients without they themself try it out first? Why make guinny pigs out of your patients? F 63 4 months
60 mg 1X day
4/22/2010
 3  depression, GAD, DOC. HUGE costipation, somnolence, loss of libido. it seems to be uneffective to me. I completely had to change med to stay well al least of my real state. i don't recommend it. M 23 1 months
60 mg 2X day
4/21/2010
 5  anxiety depression Some constipation.I take a fiber supplement and that works. No more dry mouth. Still have the ringing in my ears but not as bad and that may well be the anxity. My mood has improved. My libedo is slowly improving. I have had no weight gain and actually some appetite supression. I am sleeping with the help of meds 6-7 hours( this is the biggest help). I have not had a migraine since on Cymbalta. I no longer feel helpless, hopeless or like I don't want to go on. My negative thought that race in my mind have diminished greatly. Part of this improvement is due to I am sleeping and part may be due to the sunshine and time. I have tried Lexapro and Wellbutrin XL first with no improvement in my mood. The depression is gone, no more crying spells but I still have some anxiety. I have also been on hormones as much of this may be menopause related. Have hope and keep trying. F 52 28 days
60 1X day
4/20/2010
 4  Back Pain, Fibromyalgia & Depressio Dr recommended that I take the 30 mg/day for 2 weeks & then bump it up to 60 mg. With the 30 mg I was feeling a lot less back & fibromyalgia pain PLUS depression improved so I did not move up to the 60 mg. During this timeframe I also started PT for my back pain & think this has helped too so I want to try & get off the Cymbalta. Allelulia that I did not increase the dosage to 60 mg because I am now having some difficulty getting off the drug. Slowly tapered off for 4 weeks & have had nothing for 11 days & still feeling strange. Withdrawal Symptoms: dizzy, brain zaps, balance issues, itchy skin, difficulty sleeping...... I will persevere & will NOT go back on again! F 53 6 months
30 mg 1X day
4/19/2010
 4  Depression Weight loss, severe itching, anytime I scrath it turn into a blister,however this is the only anti-dep that has worked for me in a long,Long,LONG time, sleeplessness, some trouble pooping, the weight loss is FAb though!!! The itching is HELL!!! The scars it leaves are gross, but I would rather live with the scars than the depression.....Any suggestions???? F 28 3 months
30 mg 2X day
4/19/2010
 3  depression dry mouth,insomnia,anxiety it only somewhat works,i still need to take buspar to help relieve residual anxiety M 38 5 years
120mg 1X day
4/19/2010
 2  depression/anxiety EXTREME FATIGUE!!! OVER EATING I COULDN'T KEEP MY EYES OPEN AFTER 2PM EACH DAY. IN BED BY 6:30 7:00 PM - I AM JUST STARTING TO WEAN OFF - EXTREMELY DIZZY - AFTER 1 DAY OF BEING OFF OF IT! TOOK IT LAST NIGHT AND NOT DIZZY TODAY - THIS IS GOING TO BE AN ABSOLUTE NIGHTMARE! USED TO BE ON PROZAC AND WELLBUTRIN - HAVE NO CLUE WHY I SWITCHED - I WAS THINKING THE OTHER 2 MEDS WERE LOSING THEIR EFFECT - NOT THE CASE. i'VE ONLY BEEN ON IT 3 MONTHS - (ACTUALLY NOT EVEN 3) AND I CAN'T GET OFF OF IT SAFELY. THEY DON'T TELL YOU THAT WHEN YOU START! F 46 3 months
60mg 1X day
4/18/2010
 4  diabetic neuropathy in both feet I was concerned Cymbalta affecting REM sleep, actually blocking people from having REM sleep, and that's not a good thing at all. My doctor at the time assured me that it doesn't happen to everyone, only some people. I could not find out a straight answer on the net, all conflicting. Before, I had been on Lyrica and gained about 40 pounds because of it. After a few months I went off Lyrica because of the weight gain, and started Cymbalta, then got freaked out over the REM issue and went cold turkey. What a strange trip it's been! I have never done illegal hard drugs, but I tell you that going off Cymbalta cold turkey is probably the closest you can come. I was having lucid dreams every night. I could control what i was doing and remembered everything , every detail the next morning. I wrote about it in a public blog and a man from Arizona asked me to come out to Arizona, he was researching and teaching people how to induce lucid dreams! LOL I never took him up on it. I told him it I didn't gain weight as with other meds for diabetic neuropathy such as Lyrica and now possibly Savella. Cymbalta allowed me to sleep because before it, many nights my diabetic neuropathy was so bad that I could not sleep. Does it cause loss of REM sleep in all patients? I would appreciate an answer. thank you. F 48 6 months
30 MG 1X day
4/17/2010
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 3  Nerve Pain extreme anger, hate, and rage, nightmares, daily suicidal thoughts i have to take it, i don't have any other choice at the moment, and i'd rather be hateful than live with all the shooting nerve pain through my body. M 31 8 months
60mg 1X day
4/16/2010
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