CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  fibromyalgia Uncontrollable crying, insomnia, narcolepsy, night terrors, strange thoughts, almost lost job and my husband, profuse sweating, anxiety attacks, muscle jerks, joint pain, this Medication is seriously dangerous!!! F 42 1 years
12/21/2015
 1  Nerve pain from shingles, anxiety Immediately knocked me out for two hours. Caused blurry vision - by day four, I was unable to drive my car or read a letter because my vision was so blurry. Didn't work as well as Lyrica on the nerve damage pain. Helped with anxiety only because it knocks you out and puts you into a zombie-like state. But the worst part was the vision changes - made it completely unsafe to drive. I didn't last a week on this drug. F 38 4 days
30mg 1X day
12/17/2015
 2  Depression Lethargy, lack of concentration, brain zaps, nausea Initially helped with depression but after a while just felt spaced out and tired all the time. Didn't realise to begin with this could be side effects as had worked to begin with. Just gone cold turkey and had one week of horrible brain zaps, mood swings and nausea. Now I feel great like I'm alive again, better than being on the tabs. Wish I had never started... F 31 2 years
60ng
12/9/2015
 3   Swollen abdomen, yellowish tint to the eyes, painful liver, lethargic Although cymbalta work wonderfully for my depression in the beginning I began having some terrible symptoms about a year ago. I suddenly developed a slight yellowish tint to my eyes. I went to my gastroenterologist who did my annual colorectal and endoscopy exam. He discovered that I had a cyst on my liver. Although I had told him I had pain in my liver he told me I should not have any pain. The pain got worse. I had more test through my PCP who uncovered horses and lesions through a cat scan with contrast. Thank God I had the good sense to do some research. I called my psychiatrist who she said Cymbalta could cause those problems. I had begun to run out of the prescription, fortunately, so I stopped taking it all together. The majority of the symptoms have stopped. My Distended stomach has decreased, painful liver is nearly gone, yellowish tint of eyes has decreased, I have also lost weight since I stopped taking it and I am NOT lethargic. My mood has been uplifted since stopping the Cymbalta. F 63 10 years
60 mg 2x d
12/8/2015
 1  trigeminal neuralgia Shaky gait, painful joints, moodiness, swollen and painful feet I had to reduce dose from 60 mg twice daily to once daily. Could barely walk. This is not worth it. F 64 3 months
60 mg
12/5/2015
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 1  Fibromylgia Horrid severe side effects & do nothing for the pain . DONT TAKE!! F 50 6 months
11/29/2015
 1  supposed depression I don't know if my problems were because I wasn't depressed (I was misdiagnosed with depression when my problems were Claritin side effects). I had extreme anger and road rage. I literally screamed at a stranger over a parking spot. I also told off an attorney I was working with. These behaviors are not like me at all. There needs to be a class actiom. F 35 2 months
30mg
11/28/2015
 4  extreme back pain,and depression Initially had many side effects but almost none after 3 months. Has really helped me a lot with both issues but not completely so I'm increasing to maximum dosage today to 60 mg. Has been a life saver. I don't care if this drug is addictive because without it I probably would be dead and just hope I'll have access to it for the rest of my life. I am 66 years old. M 66 3 months
20 2X day
11/12/2015
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 1  Depression chronic pain So so sick. This drug hooks you and makes it impossible to get off. WARNING....DO NOT TAKE THIS MEDICATION. SIDE EFFECTS ON WITHDRAWAL IS HELL ON EARTH M 45 5 years
60mg
11/10/2015
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 3  Depression, chronic pain Helped very much with depression, did nothing for pain. FANTASTIC antidepressant in my case. That said, I forgot to refill once (thanks, Keppra), and went 2 days without taking it - horrible withdrawal. Be careful not to run out. F 22 1 years
60 mg 1X day
11/9/2015
 4  Depression None If I don't take Cymbata I tend to be irritable and angry. Cymbalta takes the edge off. F 60 10 years
60 1X day
11/8/2015
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 2  anxiety and chronic pain Skin reaction, dizzy, crying spells,nausea Coming off it was awful! F 39 3 days
60mg
11/1/2015
 5  major depression and anxiety The only side effect I have had is waking up at night drenched in sweat. I was on cymbalta for a number of years and it worked. Then I had several life changing events and anxiety set in and I thought it was the cymbalta not working. Then for a year and a half my doctor continued to change my meds, nothing worked. I went into an out patient program for mental illness, still nothing worked. I am now back on cymbalta and finally feeling better. I could be better so my new doctor found that I don't absorb the medication correctly so plans are to up my dose to 140 mg and add folic acid. As for all the people who have had bad experiences with this drug, all I can say is some meds work for some people and some don't. I had simalar experiences going on and off the half a dozen other anti depressants for a year and a half. You have to give the drugs a chance to work and in my experience it takes at least 4-6 weeks to find out if the drug is going to work. Good luck to all suffering with depression and/or anxiety, it will get better :) F 52 3 years
120 mg
10/31/2015
 4  Depression Cymbalta worked great for me – until it settled in with a horrible side effects. First, I thought I had the flu – achy joints and pains, but it turned out to be a side effect, which got worse at 40 mg. I was in so much pain I didn't want to move. Real bummer because it will leave my depression, anxiety, and OCD F 48 45 days
30mg 1X day
10/30/2015
 1  Depression/chronic pain #1 biggest complaint was horrible excessive sweating, I'm talking about having to change my clothes 2 times prior to just leaving the house! 30+lb weight gain, slept about 80% of the years away & wouldn't get out of bed for days at a time. Extreme fatigue, brain fog, nightmares, etc. The worse drug I've EVER taken!! Before you even consider taking Cymbalta, you NEED to have an in depth conversation w/your Dr about what happens if you need to stop taking this med. It is a nightmare to discontinue & I spent over a year w/what is called "Cymbalta withdrawal syndrome. Yes, it truly does exist & I can tell you from my heart it was the worse med I've ever tried to come off of my life! Literally opening up the capsules to count the individual beads so I wouldn't go through worse withdrawals. Brain zaps, migraines, nausea, severe stomach aches, body aches & pains, horrible nightmares, & excessive sweating. My new Dr states he believes this med should be taken off of the market! Eli Lilly LIED on the inserts stating only 1-2% had Cymbalta Withdrawal Syndrome, when actually over 50% did. Check out the number of Cymbalta court cases that are now being filed if you don't believe me. I even called Eli Lilly-yes I was completely manic after 2mos of withdrawal, & asked them what I should do about what I was going through. They stated I needed to get stomach meds, anxiety meds, & to see my Dr for other meds to treat the withdrawal symptoms. I asked if any funding was available for see a psychiatrist &/or paying for the additional meds? "No, but I will relay your ideas to my superiors". Eli Lilly contacted my Dr, without telling me, stating I was suicidal, & many other other things. This forced my Dr to fill out mandatory forms & continue constant appoin F 42 9 years
90mgs
10/30/2015
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 1  Anxiety Depression Initially had bad nausea whilst on the generic brand, but took a long time to work it out, as I was told it's the same as the original brand name Cymbalta. Then once on Cymbalta brand name, I increased to 60mg now suffer bad body aches mainly in my legs. F 42 6 months
60mg 1X day
10/23/2015
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 1  Mood Stabilizer Major Diarrhea and nausea, leg cramps, insomnia, Dr. prescribed Klonipin .25mg once a day in evening to help me sleep. i cut that in half at .125mg and it takes the edge off and I can sleep at night. feeling better in the am. and seems to work. M 47 1 days
30mg 1X day
10/19/2015
 1  Depression/Anxiety Weight gain, excessive sweating, cognitive impairment, IBS, fatigue, insomnia, falling down If I thought being on it was bad, coming off was HORRIFIC! I'm 5 months since my last dose of 20 mg. I tapered for 5 months using the available Rx strengths. I am totally disabled now. THANKS, CYMBALTA! F 45 16 months
60 1X day
10/19/2015
 1  Osteoarthritis pain Nauseous. Foggy brain. Yawning with gagging. Hallucinations. Dreams. Chills. Tingling on head and skin. Trouble walking. Bad headache. I will never take this drug again. I could not tell if what I was thinking about if I was actually doing it or not. Panic feeling. It felt like I had something heavy pushing down on my head and eyes. I would rather deal with my pain they experience this feeling again. There has got to be something better to take then this. Seems like a very dangerous drug from everything I have read about it. F 54 1 days
30MG
10/10/2015
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 2  post concussion headaches shivers, sweats, dizzy, flu like. bed time dose woke 2 hrs later, forced myself to go back to sleep, woke every hr shaking, tingling skin, itching head..... 12 hrs in laying down horrid headache, flu shivers, dizzy as hell. scared to continue taking wishing it would work. huuummmm epic fail F 52 1 days
20mg 1 day
10/5/2015
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