CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Depression and Sjögren's Syndrome I'm not sure if I had any side effects, but I never felt any benefit from taking this drug, which both my psychiatrist and rheumatologist recommended. F 25 6 months
120mg
7/4/2013
 1  Fibromyalgia osteoarthritis depress Stomach pain, muscle pain, shortness of breath, intense sweating, overheating, nausea, dry mouth, worsening restless legs, itching, tachycardia, dehydration, hypertension, weight gain, suicidal. Be careful with this med. It started out ok, but felt bad after 3 to 4 months. Then titrated off for month and a half. Feel much better with no pain meds. Scary how bad I felt. Pain 24/7 and this med is supposed to help? What a nightmare. F 59 6 months
60 1X day
7/4/2013
 1  Nerve pain Severe lethargy and some shortness of breath to the point I couldn't stand up straight. I was weak and had to crawl into bed. I only took one dose. F 44 1 days
30
6/29/2013
 1  trouble breathing.. vomitting and other symptoms. Later: overactive immune system and inflammation. SSRIs are suicide pills - you probably die. Discontinued after 1 day. Dry mouth, near nose bleeds and other symptoms after 3-4 weeks. Went to a really big hospital emergency room where they gave me some pills that helped. However, later they send me to psychiatry where they gave me zyprexa. F 32 1 days
10 1X day
6/29/2013
 5  fibromyalgia Inconsistent sleep patterns w/ night waking and sweating; constant lump in throat (feeling as though something is stuck); fogginess and inattentiveness. Before taking Cymbalta my pain throughout the day and night had become intolerable. I found immediate relief as I started taking Cymbalta. While I'm not crazy about some of the side effects, I am willing to overlook them because I am able to function. I am concerned about the withdrawl symptoms that patients have written about, and fear that I will just need to take this drug for the rest of my life. F 46 1.5 years
30 MG 1X day
6/28/2013
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 1  nerve pain, burning all over body bad mood swings, tearful, nausea, panicky, nervous, vivid dreams, drowsy during day but cant sleep for long at night, I was desperate to come off this drug with the side effects. I was on lyrica which is a god send for me bringing the burning which had spread everywhere down from feeling burnt alive & seeing no way of living to bad sun-burn which was a massive difference. I was put on lexapro later to 'help' the lyrica work with the pain as seemed to keep having to increase lyrica levels to get prev same pain killing level, but I after reading notes was annoyed as thought she was slipping me onto an antidepressant without my knowing(altho I know I was depressed by then) after had been on lexapro for 6 years was changed to cymbalta by pain clinic after I expressed concern at being in a constant head fog and wanted to come off, was told cymbalta would help pain and increase seratonin whiich is depleted after nerve damage apparently. Not in fog any more but side effects are awful, was on 60mg and he agreed to reduce to 30mg but really want to come off, just afraid of pain increases and withdrawals. Cant cope with the mood swings and tearfulness but not even sure if thats the coming off lexapro and actually just me! or is it the cymbalta at this stage! would love to hear from anyone else on this for nerve pain and their experience-thanks F 44 6 months
30mg 1X day
6/13/2013
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 1  Chronic pain, depression Severe stomach cramps, upset stomach, dizziness, spacey. It's been horrible! I have tried a lot of different depression meds, am taking Lortab for pain 2xs a day. I really hoped this would work so I could get off narcotics for pain but I would rather take the Lortab than this garbage. This med should never have been approved by FDA. F 44 1 days
30mg
6/5/2013
Email
 4  Pain and Depression I took it at night, because taking it during the day I was sick. It caused nausea, and some dizziness. Cymbalta was the only anti depressant that has ever worked for me. I was on it for 3 1/2 yrs. During that time, I felt the best that I had in my life. But, then my ins co didn't want to pay for it anymore, so I went to the company and was put on the patient prescription plan, where they give you the drug if you qualify. That went ok for awhile and then they started to get harder and harder to work with, so I decided to get off of Cymbalta. I did research, and found out that no matter how I did it, I was going to be sick. So I did it cold turkey. I would never take that drug again, every. I prayed for death for 10 days, and then it took 6 months for all of the side effects to go away. NASTY DRUG!!!! F 59 3 years
30mg 1X day
6/2/2013
Email
 1  Pain Extremely thirsty day 1 couldn't drink enough water. Could not sleep and was severely nauseated. Day 2 nausea, dry heaves, diaherrea all day long, lethargic no appetite. Day 3 nausea, diaherea lethargic and miserable. I was prescribed this drug for pain, no change in my pain at all, now feeling like crap on top of being in pain. I feel like I have a whatever, bitchy attitude not feeling like myself at all. My husband thinks I need to stop taking it because I am not myself at all. 3 days of this drug and I am done with it. Bad stuff!!!!!!! F 45 3 days
30mg 1X day
5/27/2013
 1  pain Weight gain, tired and dont care about much at all. M 47 90 days
60 1X day
5/18/2013
 1  fibro stomach pain and vimiting first drove to work pulled over ti puke could not open eyes dizzy couldnt drive climbed in the back of my car because i was confused just wanted to lay down clinching teeth seeing things loss of time layed in my car on side of road for 4 hours in 80 degree waether went to er over heated needing flids its now night time and i cant go to slleo still clinching teeth will not be taking it tomorow please if you try it dont drive and have some one a round some one could have rapef me i would have been able to do anything so scarry F 28 1 days
30 mg 1X day
5/17/2013
 3  bi polar/ depression/ anxiety morning groginess, better sleep, daytime fatigue, some periods of depression still, boredom, dry mouth, decreased appetite, strange dreams. F 23 45 days
30mg 1X day
5/15/2013
 5  Clinical Depression It works wonderfully. No more temper tantrums It works wonderfully. I get along with my family, have more energy, and have a much higher self-esteem. As the the cost, my Doctor gives me samples and I do not pay anything for them. Wish I had started years ago as my depression finds its roots in a very dis-functional childhood. M 72 9 years
30mg 1X day
5/3/2013
Email
 4  Depression/ anxiety Drowsiness, slept better at night. Works awesome I have no complaints except the cost. Thank goodness for insurance or else it's $700 a month. F 23 30 days
30 mg 1X day
5/2/2013
 2  depression, anxiety vivid dreams, decreased appetite, fatigue wasted my time with this medication, did not help depression in anyway, caused increased fatigue which only made mood worse, cymbalta is nothing "novel" just another SNRI antidpressant M 31 3 months
60 1X day
4/30/2013
 4  Depression After weaning off Cymbalta, I lost my sense of smell. It's been over a year now, and I still have not regained it. Every now and then I get a whiff of something, but it hasn't stayed. Why isn't this side effect discussed or indicated as a side effect? F 58 2 years
60 mg 1X day
4/26/2013
Email
 3  pain No side affects Getting off cymbalta: extremely difficult. Asked Dr. To decrease strength--started on 30 mg. No problem. Tried many times to stop taking, finally increased time by 2 hours for 2 weeks, then by 4 hours for two weeks, progressing in this manner and am now on to 36 hours between taking this medication. No brain 'zaps' that were horrid and I feel great with no 'down' feelings, (that are not part of my personality)! I hope to continue until cymbalta is no longer part of my pain therapy! I will NEVER take cymbalta again! Thanks, Joan F 73
60mg 1X day
4/25/2013
Email
 5  Depression/Pain from spine surgerie This has worked wonders for me as far as depression and nerve pain problems. Only problem is the extreme weight gain (40 lbs), crave sweets non stop and the price! My insurance pays part, but it's still very expensive. Will be so glad when it goes generic. Anyone have the sweet cravings and weight gain problems? Will continue taking it because it's the only thing that has helped me after trying every anti-depressant known to man!! Just wish I could somehow stop the weight problem! Any suggestions??? F 64 4 years
1X day
4/22/2013
 1  Mild depression/anxiety Switched to Cymbalta after Pharmacy screwed up and said Insurance no longer covered Lexapro (they were wrong). Cymbalta through me into a the DEEPEST pit of depression that I have ever experienced and hope to NEVER experience in my life again! This was 2 years ago! After discovering The mistake the Pharmacy made....I was promptly switched back to Lexapro and Have been so much better and feel NORMAL!!!! F 45 2 months
1X day
4/22/2013
Email
 1  for ativan withdrawal EXTREME SUICIDAL IDEATION M 48 1 days
4/8/2013

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