CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  fibromyalgia and lupus chronic pain Felt hazy and weird the first dose Cymbalta is amazing!! Pain meds didn't even touch my pain. I remember just people watching and being in tears while thinking I would love to just be able to walk care free again, without pain. Literally every part of my body hurt. The first dose made me feel strange and I decided I was done with meds. But I got to a point to where I was so depressed that I gave it another try...and OMG...I feel like me again. I can shop, I can stand and walk for long periods of time again! I just pray that it continues to work. I was on plaquenil for 9 months and it was literally killing me. My dr kept saying to give it a year. I was getting worse and worse, did my research and yep..I was right. Plaquenils rare side effects cause muscle damage and worsens chronic pain....my dr said.."sorry bout that"...Thank you Cymbalta!!!! F 45 3 months
30mg 2 a d
4/8/2015
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 1  neuropathy, back and hip pain horrid nightmares, severe nausea and dizziness, chills, dry mouth, worse numbness in arms and feet, loss of balance. Migraine Took first dose at 9 p.m. on Sat., started getting drowsy around 10pm, fell asleep and had horrid nightmares and could not wake up, finally woke up at 1am with severe nausea and dizziness, tried to make my way to the bathroom but felt like I was out of my body, I was clopping or high-stepping like a horse and weaving all over the place. Made it back to bed where I stayed for nearly 24 hrs unable to raise my head from the pillow. It is now Monday night and I still have the migraine as well as a wheezing sound when I breathe, all after one pill! I will be calling my Dr. In the a.m. F 56 1 days
30MG 1X day
4/7/2015
 1  Anxiety I wake up nearly every morning in a fog. I feel all of my cognitive functions have been muted. I feel off balance or dizzy. I feel like my vision is different. Get drunk from one beer, fear its from the heavy toll this medication is taking on my liver. Poor memory, can't concentrate, simply do not feel like myself anymore. I tried cymbalta because I was in a constant state of panic due to health anxiety. The only good thing I have to say about cymbatla is that it does take care of anxiety, but I would imagine that a simple SSRI would provide the same results without the unwanted side effects. I guess I can't say the way I am feeling is all due to the cymbalta, but there is a definite correlation between how I feel and when I started taking this medication. M 29 6 months
30 MG 1X day
4/6/2015
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 1  depression and nerve pain Bad dreams everynite and horrible interactions with atorvastatin Helped pain just a little F 77 5 years
30mg
4/2/2015
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 1  depression and pain Racing heart. Felt drugged. F 32 4 weeks
60 mg
3/31/2015
 5  Bipolar 2 Relaxing and calming effect, i am mellowed out with no more rage or agression/ hypomania. Still have a bi-monthly crying spell and a few moments of despair but that coincides with negative thinking and reflecti g on past hurt. My body feels good, no weight gain or change in appetite; very little menstrual pain, which I did not expect! I just feel so happy to be alive and I enjoy all the things I used to do; does affect my abilty to sleep for extended perioda due to some night sweats and vivid dreams; some sleep talking and outburts once or twice a week at night, but i have no sleeping partner so this is no issue for me. A small trade off for extreme happiness; I smile alot. F 22 1 years
90
3/29/2015
 1  fibromyalgia very tighten muscles of face and neck. i had never had this problem before and it stopped after i quit taking the cymbalta. F 7 days
1X day
3/21/2015
 4  Depression. RA None 64 2 years
120
3/17/2015
 4  chronic pain At first I experienced a sensation of periodic brain shocks which were a little unsettling but after the first couple days these symptoms subsided. My physical pain level has been on average anywhere from 5-7 on a scale of 1-10 every day for the last 12+ years. It has now become much less (2-3) and depressive feelings/mood much better as well. I don't understand why there are so many who have had adverse reactions to Cymbalta, I have had great results so far. F 54 1 years
60 mg 2xda
3/16/2015
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 1  Fibromyalgia Chronic low grade headache, dry throat, loss of emotional feeling, nervous agitation, insomnia, drowsy, sweating. I have tried it once before. It worked great for the fibro pain but I quit after 10 tens because of all the side effects. I'll try and ride them out but be warned......anyone taking this drug......if you can't handle it the withdrawals are wicked. Wait until you start to experience brain zaps. Wish me luck. M 51 3 days
30 1X day
3/16/2015
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 5  Osteoarthritis Before taking Cymbalta I was on so much pain medication and still had no life. I missed out seeing my son grow up because all I did was sleep and barely move because of pain. My doctor started on Cymbalta and within weeks I had my life back. I had prayed so long for an answer. Pain stole so many years of my life and cheated my son out of having a mother. Just recently I tried to reduce the amount of Cymbalta I was taking. After 3 doses at the reduced amount I could tell a difference in my pain level. Thank you Eli Lilly for giving me back my life. F 55 5 years
120 mg
3/14/2015
 1  nerve pain from a stroke Woke up 5,hrs after taking one diarrhea vomitting all muscles sore 45 1 days
30 mg
3/13/2015
 1  Depression Neuropathic pain for MS I was recomnendedI this drug by my neurologist to help with MS symptoms and found my brain could not function as it had been. Very confused and bad memory loss, which was extreme considering I had to hold down my job.One day I felt extremely unwell and went to the doctor, while is was there explaining how I felt I had a huge reaction. Severe pains in my head with my blood pressure so high the machine would not work. I was rushed to hospital in an abulance in which the ambo thought I was not going to survive. I was in hospital for one month with at least five episodes per day of extreme debilitating pain and put on numerous drugs, mri scans, lumbar puncture etc. I felt my head was going to explode with the pain and was later told I could have died through the blood vessels bursting in my head. So I agree with the comments 100% it has been the EVIL PILL for me and would not recomend it to anyone else. F 55 6 weeks
30mg 1X day
3/11/2015
 2  Fibromyalsia jaw clenching, increased thirst, cold shivers, Exhausted and yawning constantly but couldn't sleep well. Emotional numb feeling. F 31 4 days
30
3/10/2015
 5  depression and anxiety The first few days were like a fog. I didn't eat much due to nausea and then it was fine. Had a headache too. Difficulty with reaching orgasm. I stopped taking it cold turkey ( I actually just forgot to use it for 5 days) and suffered 0 side effects or reactions. Originally I was put on it with a view to ceasing after 6 months but I was terrified I'd revisit the horrible depression and anxiety so I stayed on it. F 40 2 years
3/5/2015
 3  Back and nerve pain Tingling hands, memory loss, confusion, balance issues, vertigo, joint pain, teeth and ear pain, high BP, muscle twitching or jerking, blurred vision This was worse when I went off 1st 60 mg cold turkey, issues there but not real bad. 2nd 60 mg took skipping day in between for 5 days then off. Whamo! Hit with major issues kept me in bed for a week. Nausea, vomiting, chest pain, nose bleeds, headaches, dizzy, food made me sick looking at it, UTIs, 5-8 bowel movements daily, knowing this was coming I started eating lots of veg. Fruits, taking 7000 IUs daily Vit D3 (not D2) potassium, magnesium, multi Vit. Drinking lots of water with lemon to detox liver some, and used my oxygen all day and nite 2 liters especially when going thru bad part. As a result in one week I was thru the worse. At my worse u can do nothing, no work, no thinking, no walking, just sit or lie down. It was horrendous but hopefully over. I'm now 10 days cymbalta free and symptoms still there but not severe. Still wouldn't be able to work but I'm up and out now. My head is clearing up, headaches gone, vertigo only laying back, I can eat but still healthy diet and vitamins and drinking water. My Dr was aware I did this but wanted me to do long withdrawal. I have strong personality, pain doesn't bother me alot as I've been in it for 15 or so yrs. and I wasn't taking this for mental issues, just to help with pain in right hip as it prevented me from walking and caused balance issues. So not everybody will fly through this as quick as me but being ready mentally, eating properly, taking Vits before hand and for me having oxygen at home helped TREMENDOUSLY! E F 67 4 years
60 MG 2 X'
2/28/2015
 1  Bipolar Mood Disorder Sensation of electric shocks in my brain, tingling in my hands, confusion, headache, nausea if I'm ever unfortunate enough to miss one dose. Cash price $200 a month on average. My pharmacist told me everyone is on this stuff. Lily is making a huge profit on the depressed, anxiety ridden, chronically pained without any conscience. F 47 2 years
60
2/25/2015
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 1  Anxiety Side affects: Tingling in hands and feet, brain zaps, dizziness, insomnia, paranoia, confusion, disorientation, depersonalization, tongue necrosis, early dementia, hair loss, skin boils, Crying spells, depression, worsening of anxiety, rage, dehydration, appetite loss, but weight gain, mood swings, nausea, fatigue, restless leg syndrome, etc. etc. etc. YES IM SERIOUS!!! THIS DRUG IS EVIL and has stolen 2 years of my life... because the side affects slowly creep up on you. I honestly thought I had multiple sclerosis and contributed a lot of my symptoms to other things. PLEASE LISTEN when I tell you to RUN... Not walk away from this drug!!! Shame shame shame on you Eli Lilly! CYMBALTA WILL KILL YOU!!!!!!!!!!! And for anybody who says they don't have side affects, or give this drug a highly satisfied rating, you just haven't taken it long enough!!! Careful when stopping this drug as the withdrawal is gruesome!!!!! F 32 1 years
30
2/23/2015
 1  anxiety and pain On 5th day I had overwhelming itching and genital blisters. Before that decreased appetite and nausia. I stopped taking after 5 doses. 4 days later and developed cold sores on mouth and genital blisters slowly going away. Would not recommend this F 49 5 days
20 mg
2/22/2015
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 3  Pain Have taken 4 tablets so far (4 days) and side effects seem to be easing off. 4 hours after taking first tablet i felt like vomiting, had cold sweats, shaking and a mad urge to clench my jaw. On day 4 I now have this urge in my jaw, i jawn about 8000 times a day and feel a weird sensation in my body during and immediately after. Sleep no issue. Pain howeverassively improved. GP said stick it out for first 14 days so will see how i get on. F 28 4 days
60mg
2/20/2015
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