CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2744 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Fibromyalgia, neuropathy, etc Dizziness Wished I had not been misdiagnosed so many times over the years and finally got the right diagnosis and medication. It has helped me tremendously F 45 5 weeks
30 mg
9/8/2016
Email
 5  Major depression, severe anxiety Weight gain but this can be controlled, poor cognitive function, loss of short/medium term memory Was prescribed this drug to deal with treatment resistant depression over a year ago and it was so effective that I was able to cease taking it without any side effects..suffered a relapse in recent times and resumed taking the cymbalta..it's cheap and cheerful and it works..I put on more than 14 pounds the last time I was on it but I am watching my weight this time..while my cognitive function is shocking and my memory even worse, I have got used to it..it's a small price to pay.. F 53 1 days
60
10/2/2016
 5  Neck pain/ osteoarthritis Constipation and weight gain This drug has been life altering. I was ready to end it before I started taking cymbalta. I am enjoying life again. I feel the best when I also practice yoga a few times a week and get regular massages. F 46 1 years
60mg
8/21/2016
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 5  Neck pain/ osteoarthritis Constipation and weight gain This drug has been life altering. I was ready to end it before I started taking cymbalta. I am enjoying life again. I feel the best when I also practice yoga a few times a week and get regular massages. F 46 1 years
60mg
8/22/2016
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 5  Depression Tension headaches, nausea, jittery feeling Immediate relief from depression on the second afternoon. Side effects also getting better. Completely worth it to feel better! F 14 3 days
20mg
2/20/2016
 5  Depression, chronic pain Sweating I've suffered with suicidal depression and the pain of Cervical Dystonia. Cymbalta helps with both. My weight has been unaffected; pain flare ups are rare but can be severe. My MD and I are considering a slow down titration as a trial. F 63 10 years
90 MG
3/13/2016
Email
 5  Foot Pain, Joint pain loss of appitite, nausea This drug has been a life saver. I have had severe foot pain for 3 years. Have seen many doctors, had food injections, started on methotrexate, etc. Since starting Cymbalta, I can get out of bed without holding onto something in severe pain. I can now actually work on my feet all day and come home and go for a walk with the dog. I can wear any shoe now without all the different orthotics in them. I feel like I have my life back and can finally start exercising again to get rid of all the weight I gained while being inactive due to the pain. I am grateful my primary doctor put me on this medication. F 49 14 days
1X day
1/27/2016
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 5  Nerve,joint,PTSD post car crash Have had some dry mouth/throat but no other side effects. This medicine has helped TREMENDOUSLY. I was rear-ended while parked and had numberous fractures, spine damage, nerve damage, and severe PTSD. My dr put me on neurontin first but I ended up in the ER. Second day of neurontin, my vision became so blurry I could not see and my blood pressure was off the charts. I was very worried about more nasty side effects with cymbalta. As far as I'm concerned, this medicine is a Godsend. After about 5 days, I felt the best I've been since my car accident six months ago. It's expensive but for me it's awesome! F 38 2 weeks
60
12/26/2015
Email
 5  Panic disorder and nerve damage Like with Celexa, I had the usual 2 weeks of side effects. Stomach upset, dizzy, shaking, sweating, insomnia. After the first 2 weeks, which any good Dr. should have warned you about, I'm fantastic:) Celexa and Cymbalta both have a 2 week side effect allotted time, both at the beginning and when you're quitting. Keep in mind that it metabolizes out of your system in 72 hrs. I'm finding most of the reviews are coming from people who were not given a heads up. Should have stuck it out for the 2 weeks. F 30 2 years
60 mg
8/10/2014
Email
 5  panic attacks, anxiety Side effects- jumpy,nervous,hair loss.blurry vision. Big reason I stopped.was on it over ten years.it kinda ran its course. F 56 1 years
60mg
5/4/2014
Email
 5  for pain management Cymbalta has helped me get my life back. The side effects are minor compared to the benefit, dry mouth, gained around 10-15 and crazy vivid dreams nothing scary. I recommended it to anyone that is not suffering from depression or diabetes. It works better then opined, staying clean and getting things back in order. F 37 1 days
40mg
3/17/2014
Email
 5  depression bipolar chronic pain I've only been taking Cymbalta for a few days but I already feel so much better. I finally have the energy I always wanted, I'm being productive, and enjoying my life. Side effects im experiencing are: greater sensitivity to light and taste, headaches, and jaw clenching. Since I just started I don't know if these symptoms will continue, or for how long if they do, but I am willing to put up with them. F 30 4 days
30 mg
4/1/2014
Email
 5  osteoarthritis None. The medicine has got me back running and swimming. I feel like my old self (two years ago). F 52 1 months
20 mg
9/27/2013
 5  Depression Sore throat, tiredness, headache, weight loss. Amazing medicine for me. No more crying everyday. No more getting upset at simple things. I weighed 165lbs when I started taking cymbalta and I'm 115 now (I'm 5'7). F 38 2 years
30mg
3/6/2014
 5  for sleep I have very high tolerance with any kind of sleeping pills I was once on abieim and my doctor changed by medication to50 mg of trazodone and that doesn't help. F 54 2 days
2X AN
1/31/2014
 5  Depression/Back pain Vivid and weird (but not scary)dreams Significant night sweats Nausea/vomiting and headaches if I forget a dosage. I tried many anti-depressants. I had various side effects and minimal results. My MD was almost out of options when Cymbalta came out. And she thought it would be a good match since I also had back pain. I was on it very early. It turned out to be the only one that gave me consistant relief and let me feel too, rather than be flat. I find the dreams interesting (almost fun). The dreams get stronger if I change dosage or forget a dose. I have missed dosages at times and I get significant nausea and headaches. I don't consider that a problem however because if I ever discontinue Cymbalta, I'll step it down slowly to avoid symptoms. The night sweats are significant, but I always forget it's a side effect of Cymbalta and blame it on peri-menapause, so I just feel like it's ok to live with it. Anyway, I recommend Cymbalta, but after seeing the comments I guess people really have different reactions so try it; especially if you didn't have good results with other anti-depressants, but if it's not right; talk to your MD and get off of it. Oh, I haven't noticed any improvement in my back pain. Although I wonder if I went off of it whether I would then notice that it had been helping. F 48 4 years
1/22/2010
Email
 5  Musculoskeletal pain due to hemochr Side effects were quite severe for the first 10 days (mood swings, nausea, diarrhea, nervousness) but after that almost nothing I have found cymbalta has helped me with pain significantly and almost no side effects after the first week or so. I read so many bas reviews of this drug, I just wanted to offer a positive one. F 39 6 weeks
60 mg
8/6/2015
Email
 5  depression and chronic pain No side effects!!! A miracle drug. No more pain. My mood was so much better. More energy. Could not continue to afford it. Fast forward 3 years later. Depressed. Pain. No energy. Started taking cymbalta again..not the same. Too many bad side effects! NOT THE SAME!!!!!! What happened?? In 2007 I started taking cymbalta and it changed my life. For the first time in a long time I felt normal. In 2012 tried it again, made me sick. Don't know what is different about it but it's not the same. Now I would rate it terrible!!! F 65 2 months
30mg.
2/2/2015
 5  Depression/Fibromyalgia Have some minor brain fog at times and short term memory issues at times, but these could be due to age or taking Ambien for insomnia. I couldn't honestly blame it on Cymbalta Have had life-long low to mid grade depression (familial) and was put on antidepressant 19 years ago after a major depressive episode. I intended to take for a short time but felt the best I had in years mentally, so didn't want to give them up. Talk therapy wasn't effective at all. Also developed extreme body pain/exhaustion a few years earlier and was diagnosed with fibro. About 8 years ago my doctor asked if I would switch to Cymbalta after she said she had several fibro patients responding well to it. It has helped with the pain and depression. My quality of life much better and minor side effects. I am medication averse and always go to the alternative/holistic approach before resorting to any meds. I have a very healthy lifestyle, exercise, eat well, maintain BMI 19/20, etc. Recently I wanted to try to go off Cymbalta to try to be medication free. Knew about possible severe side effects with going cold turkey, so just reduced dose to 15 mg/day for 3 or 4 weeks, with no issues. Then tried reducing to 10 mg. After a few days I was back to having circuitous negative thoughts/mental stress over very minor issues. This was what I was so relieved to have end when I started on antidepressants. I had a sense of wellbeing for the first time I could remember. I decided to try to stay on 15 mg. Cymbalta or would go back to 30mg. if necessary, but my life is unquestionably better with Cymbalta. F 66 8 years
30 mg 1X day
5/30/2015
 5  anxiety I feel awesomely numb while taking Cymbalta. After only a couple of weeks taking the drug my thoughts improved, anxiety stopped completely, and I could hear what people are saying better. I do notice that my memory is not great and that I love sleep! It definitely got rid of what were hypochondriac-like thoughts, and completely. Sleep is amazing on this stuff. However, I'm scaling back from 60mg for 6 years to 30mg because I do notice my memory is affected. F 39 6 years
60 1X day
9/22/2014

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