CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  depression I am currently trying to wean off of cymbalta and the side affects are horrible. Brain zaps, shales, chills, memory loss, word loss- I just quit my job and can't imagine having to work like this. It worked for a while but I gained so much weight. The last 6 months I have gained at a rate of 5lbs per month. F 34 2 years
60 1X day
10/6/2011
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 2  depression/anxiety constipation,exhausted,very hungry This medication so far hasn't been the best. I am only 16 years old and my psychiatrist suggested this. Mostly older adults take this medication but I have major depression and GAD. My suicidal thoughts have still not gone away. I guess I should wait a few more weeks. I am hoping it wont get worse. F 16 7 days
30 MG 1X day
1/25/2012
Email
 2  depression I started have extreme sweating. I couldn't do anything without becoming soaked. I also had severe insomnia and had to take a lot of drugs to make me sleep. I didn't connect any of this to Cymbalta until I ran out and just used the Elavil I had. My sweats have gone away and then I notice that I could take half or a third of the medicine I took before and could go to sleep. My mind doesn't race like it did. I can't believe how long I suffered all due to Cymbalta.. I couldn't even go outside in the summer because I sweated so bad and would get sick and dizzy. All of it is gone now. F 56 3 years
90 1X day
11/22/2011
 2  lower back pain an anxity what a horrible experience, I am 23 years old .I have tried many medacations in my life an this Drug has some of the strangest effects ever . I took it for the first an last time . I was completly emotionless had deep convo with an ex which should have made me cry or feel sad in some way yet i was completly unaffectedand an felt nothing . I couldnt sleep till about 3 in the morning and to my surpise was bright an bushy taled at 6 30 smilieing super happy i didnt even know who i was felt like i was a robet .An extremely smart movtatived one who was super foucsed its about 1 pm now i refuse to take another dose althou i am frezzeing and have chills dry month and zero desire to eat . Honestly it may be a mircle drug happy helps you lose weight cuz u have zero need to eat.Your mind is so open to learning im just extremely scared that i will need it everyday . so good bye mircle drug just flushed a 2mos supply down the toliet F 23 1 days
60mg 1X day
10/31/2011
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 2  Anxiety and depression headaches, numbness in face. F 26 4 months
60mg 1X day
1/13/2012
Email
 2  anxiety, depression, muscle pain nausea, vomiting, headache, head buzz , dizziness, weakness, unable to get up. I only took it once that was enough, the worst day and night ever, I have never felt so ill, it took three days for these effects to go away F 27 1 days
30mg
6/8/2012
 2  Bipolar depression Less depression, although still had low-moderate level at times, but couldn't "feel" much of anything. Emotionally numb. Didn't cry at my own sister's funeral!!! Felt numb, robot-like. Also couldn't orgasm. Cymbalta seemed to deaden everything. Reduced dose now to 30 mg and already feel myself coming alive. This is a strange med, and I've been on a lot!! F 54 8 months
60 mg
8/25/2012
 2  depression I broke out in hives on my cheeks it was very itchy and burned went to hospital once they said it was contact dermatitis then my other cheek did the same they say It's the cymbalta. I read online you should not take this with trazodone... I believe my psychologist is a moron because I've had problems with other depression Meds mixed with trazodone. I'm going to see if I can get this changed. I'm not sure if its the mixture or if its just cymbalta F 25 7 days
30
6/29/2012
 2  Depression and Sjögren's Syndrome I'm not sure if I had any side effects, but I never felt any benefit from taking this drug, which both my psychiatrist and rheumatologist recommended. F 25 6 months
120mg
7/4/2013
 2  depression & anxiety Fatique, lethargy, night-sweats and uncontrollable muscle jerks. Cymbalta works to reduce my anxiety, but has done nothing at all for my depression. My physician says I should be doing things that mimic being "normal," but I do not have any energy or enthusiasm. Physicians do not have a clue...unless they've experienced extreme depression, they have no basis for advice-giving. So now I'm quite addicted to this drug. I have the alarm on my phone set to alert me to take the capsule, but if I miss one dose, the following day I have brain zaps and audible buzzes, very disconcerting and I do not look forward to quitting this drug. I've also gained weight with no change in my normal eating habits, which are quite healthy. Another example of the pharmaceutical companies pushing a drug into the market and the medical profession pouncing upon it. I am quite confused with the variety of conditions Cymbalta is prescribed for. F 63 9 months
60 1X day
4/27/2012
 2  Anxiety GI upset, change of personality After a therapeutic level of Cymbalta was reached in my system, I thought Cymbalta was great...I was feeling more relaxed than I had been in a long time. I ignored the stomach pains and constipation because I figuerd I'd rather be happy and have to take an occasional stomach med. After a couple months, I realized I had nothing to say anymore...I could not make conversation to save my life. I wasn't stressed anymore, but my self-esteem was shot as I thought I was the most boring person ever. I ended up tapering off over a couple weeks and am back to square one with my anxiety, but have a personality back. F 28 5 months
30 mg 1X day
2/22/2012
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 2  Bi-polar Depression I am so tired. All the time. I can have nightmares. Sweat dripping off me in the morning. if i miss a dose I am in a daze. I can get cold alot. Body jerks, My body can feel bruised all over. I got dizzy and feel over once. lowering my dose also. i am suppose to go down. 30 mg. but.. dam I don't wanna hurt or get sick. driving sometimes when going up or down off this is not smart. I would never had agreed to be on this if i knew how painful and sick I would get if i missed a dose or going up or down on this med. Due i feel any better Hmmm... no not so much! F 38
90 1X day
4/28/2012
 2  Depression Withdrawal complete hell Not worth The numbness of life F 45 3 years
120
3/17/2012
 2  Depression and Fibromyalgia Headaches, changes in vision (sharp things made me paranoid), mood swings, dry mouth, thirst I did not like this medication. My doctor put me on it because she thought it would help with my daily aches and pains as well as major depression. It worked fine for about 2-3 months but then I started getting headaches and dry mouth. I was constantly thirsty. I stayed on it but then my vision started changing. I would go to a store and the clothes racks that stick out would really mess with my eyes. I became paranoid that something would poke me in the eyes. The final straw was the mood swings that made me so irritable that I would yell at my parents for no reason. F 25 1 years
60 mg 1X day
8/17/2012
 2  Anxiety & Depression Insomnia, Nightmares, Exhaustion, Initial Appetite Loss, Severe agitation Started 30 MG - 1st night, horrible nausea. Things were fine, increased my dosage. Stopped being able to fall asleep, stay asleep, constantly exhausted, vivid dreams and nightmares, extreme agitation with everyone and everything F 20 3 weeks
60 MG 1X day
1/7/2013
 2  depression, likely job-related onthe 16th day, had a skin irritation on my right hand, mimicking contact dermatitis, 21st day, started on my left hand. 32nd day, started on my right foot. tapering off this med, all better except right hand, but it's coming along no problems tapering off this med, except crying jags returning. F 47 2 months
30 mg 1X day
9/10/2012
 2  for fibromyalgia pain I and my sister experienced development of glaucoma, unbearable withdrawal symptoms like insomnia, brain glitches, brain fog, irritability, taking 6 months to taper from 60 mg to 30 mg. Another 4 months and I am down to about 20 grains, however much that is - have to open capsule and count little grains Even thought it initially halted my FM pain, I would strongly advise against taking Cymbalta F 59 6 days
60 1X day
11/2/2012
 2  anxiety, depression Hitting the wall with too many life problems resulted in the discontinuation of Effexor and immediately on to Cymbalta. At 60 mg. 1x day for a month I felt fine. Doubling the I felt emotionally flat, no emotion. I had impulsivity, I think just to see if I could get some feeling. Constipation was awful with a large weight gain that put me out of all clothes save sweats. I had balance issues, and would get the shakes before my second dose. I did get permission to cut the dose to 60 mg 1x a day, but it has been pure hell going down as I have a whole set of new side effects. I am exhausted and sleep with vivid dreams such as I never had before, I am a step away from a migraine daily. I have sweats and then freeze. My heart races at rest and I am getting moody, even losing my patience with my dog. I have joint pain and can hardly move. Originally at 60 mg I felt great, and until 2 days ago, I didn't know I was on the highest dose. In hindsight, I would have never started it. I also had a sudden hearing loss experience and am now totally deaf in my left ear; it is sensioneural and will never return. I don't know if it is related but I lost my job because of it. I would like to know if anyone else experienced a hearing loss as my brother-in-law is a doctor in an unrelated field and he has never heard of such a thing. If you did, please contact me. Thanks. F 56 5 months
60 mg 2X day
1/22/2013
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 2  depression and fibromyalgia I experienced a completely "spaced out feeling" which was only worsened by the dizzying relentless nausea. I feel so tired I can barely function. I have only been on this drug for eight days. Please; Could anyone tell me how long the nausea lasts? I am considering quitting although I was really hopeful about this one. F 34 8 days
8/6/2006
 2  Depression/Anxiety HIGH BLOOD PRESSURE!! Lack of emotions (neither happy or sad), heart palpatations, very little sex drive, VERY tired! Cannot get enough sleep!!!!! F 28 2 months
8/21/2006

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