CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Fibromyalgia, Depression It does help; recently depression has increased F 48 3 years
120
12/20/2016
 3  Anxiety/OCD Lots of energy/ weight gain I started 2 yrs ago and it helped so much. I praised this drug so much. Then 3 mths ago I hit major depression wanted it to go away. So my doctor prescribed 60mg instead of 30mg I thought it was going to help but the depression is back. I have two beautiful healthy children and a wonderful marriage. I just want to enjoy it again. I'm thinking about going off of it with help of my doctor. Could it be the medicine making me horribly depressed? F 35 2 years
30 mg
12/29/2016
 3  Fibromyalgia I took Duloxetine (Cymbalta) 3 hours ago. So far, I am Jittery, have the chills, extreme diarrhea, super bad nausea and I felt like I needed to lie down only to toss and turn and not be able to sleep. Muscle pain has subsided. With that being said though. It's been 3 hours, I ALWAYS have many side effects happen when starting a new medicine and it also did what it was supposed to and made my pain better. I will continue to take this dose. I am supposed to increase to 40mg in two weeks but I'll see how well the 20mg does. F 28 1 times
20 Mg
3/14/2016
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 3  Depression Horrible trying to stop. Should not have taken it so long. Doctor said I would be on it the rest of my life. I don't think soooo! I'm in the process now of trying to stop. F 61 9 years
60
3/29/2016
Email
 3  Fibromyalgia Brain fog, weight loss So far no real help with the depression, anxiety, or pain, but no real annoying side effects to speak of (brain fog trends to happen with my pain anyway) so I'm hoping a larger dose will come with my next appointment and success will come then. Fingers crossed! F 29 2 months
30 mg
4/18/2016
 3  Major Depression Not sure if side effects were from this medicine or others (Niasin and Zetia for high cholesterol), but I had dry mouth. I was still depressed, and I don't know if it was working. When I forgot to take a dose on time, I had nausea. I went through a difficult divorce and had a lot of other big changes in my life (moving to different house, starting a new business, money issues), but I was still very depressed so I didn't think meds were helping. I stopped taking Cymbalta when I had skipped a dose and was too busy to deal with the nausea. I didn't really intend to stop taking it, but I didn't want to deal with the nausea so I just never took it again. Didn't notice any difference for at least a month. But then I went through more stress, moved again, downsized my business, had staffing problems, no family or close friends nearby, etc. Two months after stopping med, I had extreme memory and disorientation problems. That is getting better because I don't have as much on my mind now, but I can't concentrate, am very lonely and depressed and confused. I have a lot of bad crying jags and feelings of homelessness and fear of the future. I might go back on it, but when I moved 4 months ago, I never finished unpacking and now I can't find my meds so I would need to get a new prescription, but it is so hard to get an apt to see a Dr. I am just generally confused and can't make decisions. I feel like there is no one I can depend on, and no one would notice if I disappeared. F 58 3 years
60 mg 1X day
1/5/2016
 3  Depression, chronic pain Helped very much with depression, did nothing for pain. FANTASTIC antidepressant in my case. That said, I forgot to refill once (thanks, Keppra), and went 2 days without taking it - horrible withdrawal. Be careful not to run out. F 22 1 years
60 mg 1X day
11/9/2015
 3   Swollen abdomen, yellowish tint to the eyes, painful liver, lethargic Although cymbalta work wonderfully for my depression in the beginning I began having some terrible symptoms about a year ago. I suddenly developed a slight yellowish tint to my eyes. I went to my gastroenterologist who did my annual colorectal and endoscopy exam. He discovered that I had a cyst on my liver. Although I had told him I had pain in my liver he told me I should not have any pain. The pain got worse. I had more test through my PCP who uncovered horses and lesions through a cat scan with contrast. Thank God I had the good sense to do some research. I called my psychiatrist who she said Cymbalta could cause those problems. I had begun to run out of the prescription, fortunately, so I stopped taking it all together. The majority of the symptoms have stopped. My Distended stomach has decreased, painful liver is nearly gone, yellowish tint of eyes has decreased, I have also lost weight since I stopped taking it and I am NOT lethargic. My mood has been uplifted since stopping the Cymbalta. F 63 10 years
60 mg 2x d
12/8/2015
 3  Depression, anxiety Only a slight headache and maybe curbed appetite. I feel a little better on day 2, but it is early on to identify if correlation. Perhaps I'll add another review after more time. F 26 2 days
30 mg a da
5/3/2014
 3  Fibromyalgia Weight gain foggy brain It did help with fibro pain some what F 38 3 years
60 mg
12/10/2017
 3  bi polar/ depression/ anxiety morning groginess, better sleep, daytime fatigue, some periods of depression still, boredom, dry mouth, decreased appetite, strange dreams. F 23 45 days
30mg 1X day
5/15/2013
 3  Depression/Anxiety EXCESSIVE Sweating- Badly at night. Fatigue 24/7 , Unmotivated, Don't care about anything. F 23 2 years
60
10/30/2013
 3  Depression, fibrogylmia Sweating, dizziness F 53 1 days
120mg
12/29/2013
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 3  pain from spinal nerve damage Weight gain ...40 + pounds, loss of sex drive Takes the edge off my pain. Very hard to quit taking. Had open the capsules to count the liitle balls inside the capsules and take 10 balls less per week. They need to make smaller doses! F 58 3 years
60 mg 1X day
9/29/2013
 3  depression, fibromyalgia, pain I get extremely dizzy when I stand up. Neasuated, exhausted all the time. Sleep 16 hrs a day. Can't work like this. Does the exhaustion go away. Was on 60 mg two months now 120 for a week so.far. helps my pain..I haven't noticed it help my depression yet. Had a mental breakdown a month ago. F 42 2 months
120 mg
9/16/2013
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 3  mild depression,arthritis, etal Tinnitus extreme, brain fog/inability to concentrate/memory loss " what?", complete life apathy, depression, hoarding, excessive clothes shopping to feel & look better (broke), dizzy, clumbsyness(sp?), complete loss sex drive, & other stuff, (I think) Tried to get off this crap by dosing down, but, increase pounding tinnitus so bad, had to go back on. It did lessen muscle/skeletal pain, but, no Way eliminated. Dr tried to substitute Prozac, I still don't understand the coorelation, maybe he just thought I was lying about having pain!!! Who would put themselves thru agony? Did I mention increased anger, small bit. If you don't need it, don't start. I get the feeling my cocktail of meds will mean my demise before my health situation. F 54 3.5 years
90 1X day
9/14/2013
 3  Depression, Anxiety First few days of taking cymbalta: Nausea, Thirst, Sleeplessness I had taken other anti depressants in the past such as Lexapro and Zoloft. I switched to Cymbalta after the others stopped working. The side affects I experienced when I started taking Cymbalta were mild as my body was already adjusted to anti depressant medication. Many of the severe side affects such as vomitting, nausea, restlessness,etc that people are describing happened to me the very first time I started taking an anti depressant, which was at the time Lexapro. This is because my body was not used to the med and I had to wean myself onto the med. Instead of taking the whole dose, start with a quarter for about 3 days then half the dose another few until you can handle the full dose. I almost gave up on lexapro because it made me sick at first but the severe side affects did stop. However, do contact your doctor if the affects persist as it might not be the right medication for you. F 22 22 days
1/21/2010
 3  Back and nerve pain Tingling hands, memory loss, confusion, balance issues, vertigo, joint pain, teeth and ear pain, high BP, muscle twitching or jerking, blurred vision This was worse when I went off 1st 60 mg cold turkey, issues there but not real bad. 2nd 60 mg took skipping day in between for 5 days then off. Whamo! Hit with major issues kept me in bed for a week. Nausea, vomiting, chest pain, nose bleeds, headaches, dizzy, food made me sick looking at it, UTIs, 5-8 bowel movements daily, knowing this was coming I started eating lots of veg. Fruits, taking 7000 IUs daily Vit D3 (not D2) potassium, magnesium, multi Vit. Drinking lots of water with lemon to detox liver some, and used my oxygen all day and nite 2 liters especially when going thru bad part. As a result in one week I was thru the worse. At my worse u can do nothing, no work, no thinking, no walking, just sit or lie down. It was horrendous but hopefully over. I'm now 10 days cymbalta free and symptoms still there but not severe. Still wouldn't be able to work but I'm up and out now. My head is clearing up, headaches gone, vertigo only laying back, I can eat but still healthy diet and vitamins and drinking water. My Dr was aware I did this but wanted me to do long withdrawal. I have strong personality, pain doesn't bother me alot as I've been in it for 15 or so yrs. and I wasn't taking this for mental issues, just to help with pain in right hip as it prevented me from walking and caused balance issues. So not everybody will fly through this as quick as me but being ready mentally, eating properly, taking Vits before hand and for me having oxygen at home helped TREMENDOUSLY! E F 67 4 years
60 MG 2 X'
2/28/2015
 3  Pain Have taken 4 tablets so far (4 days) and side effects seem to be easing off. 4 hours after taking first tablet i felt like vomiting, had cold sweats, shaking and a mad urge to clench my jaw. On day 4 I now have this urge in my jaw, i jawn about 8000 times a day and feel a weird sensation in my body during and immediately after. Sleep no issue. Pain howeverassively improved. GP said stick it out for first 14 days so will see how i get on. F 28 4 days
60mg
2/20/2015
Email
 3  Scoliosis{Spine} pain Occasional headaches,and I have gained over 25 lbs!!!!ARGH!!! BUT! It is a miracle for the pain.Not sure its worth it tho,if the weight gain continues to be an issue.. Not sure the pain numbing is worth the amazing weight gain... F 54 5 months
30 mg 1X day
1/28/2015

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