CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  major depression nausea at first, but that went away. Lost some weight, keeps me from eating like I was. I was already taking Wellbutrin but the depression was the worst I had ever had and doctor added the cymbalta 30 mg a day. I had high blood pressure and migraines so Inderal was added. I feel like a different person, feel so much better. Am afraid now the doctor will take me off this combination. Blood pressure is back to normal, cut down on the inderal to 20 mg a day. I have read the side effects of coming off the cymbalta, sounds really scary. Doctor mentioned me being on the cymbalta for about a year. Has anyone been on the cymbalta longer and with the combination of other meds that I am taking. F 55 4 months
5/7/2007
 5  depression and anxiety Hot flashes and restless sleep for the first 4 weeks. Decreased appetite (which is a plus to me), increased libido I have had positive comments from family and co-workers about my overall improvement in attitude, patience, moods etc.... F 35 60 days
7/3/2007
 5  depression I can't be sure since I am on many RX's but I think weight gain other than that nothing. Saved both myself and my daughter from deep depression pretty quickly. F 50 6 months
6/27/2007
 5  Depression None worth mentioning I had tried multiple ADs with no benefit... this one has been a lifesaver. F 43 3 years
9/22/2007
 5  Moderate Depression Nausea first few days. OTC motion sickness pills helped, but they leave me drugged/tired. I cannot orgasm, yet I have increased drive. Go figure. Mild insomnia, but I have always had that, so it's hard to say that it's from the Cymbalta, EXCEPT that when I wake up during the night, I'm WIDE AWAKE. I feel great! Wellbutrin worked for me for a while, then quit. Lexapro helped a bit, but left me with sexual difficulties. I then switched to Buspar, and that did nothing for my depression. I tried each of those for approximately one year each. I just switched to Cymbalta, and I'm so much happier! I haven't felt like this, on a regular basis, in a long time! I smile a lot. I blow things off easily. I also am less happy-emotional, too. I was extremely bad about that..I'd get choked up at the simplest things. Anything sentimental..forget it. I still have the same *feelings* just without the physical effects. I'm very happy. I am going to see if I can take something to counteract the sexual side effect and report back. F 26 1 weeks
8/7/2007
 5  depression, anxiety, pain mild nausea and stomach upset, mild headache I have suffered severe pain, numbness and tingling in my left arm, severe pain in my left leg for more than 5 years. Nothing else has ever relieved it. After 2 weeks on this drug, the pain is gone. I am also free of anxiety and my depression is lifting. I'm like a new person. Thank God for Cymbalta! F 55 14 days
6/12/2007
 5  Anxiety/Depression For the first week, I experienced extreme tremors and extreme fatigue. I was thinking about stopping the med because of the fatigue, but I persevered. After about two weeks, those side effects were gone. I love the way I feel. Happy. Way more calm. Confident. Creative. Excited about life. Motivated. I do have some strange side effects: hesitation to urinate, yawning (big yawns), some insomnia, some fatigue (due to insomnia?), missed period (not pregnant), and the craziest is very vivid dreams with many details. Some are nightmares and some are wonderful. I compare it to the movie Jacob's Ladder Heaven and Hell mixed together....only not quite so bad. :) I have only recently began taking Wellbutrin and Cymbalta. Wellbutrin for about one year and Cymbalta for two months. I feel like the benefits of Cymbalta are the reason I decided to try medication (I hate taking medication). The concerns I have are that I want to feel this way without medication. Also, I am very concerned about missing a period since I want to have kids some day. F 32 2 months
4/10/2007
 5  Chronic pain Slight nausea for the first week or two and ongoing night sweats. I started having relief of my widespread pain from osteoarthritis, osteoporosis and back pain within 24 hours! Cymbalta has increased my quality of life as my pain is now at a tolerable level. F 57 6 weeks
7/4/2007
 5  fibromyalgia and depression nausea about 4 hours after taking the med lasting rest of the day,sweating in the face, severe constipation Ihave only taken cympalta for 5 days and already I feel like a new person. My mood and energy are better than they have been in months. I feel like i have found my light at the end of the tunnel. 1st week taking 30 mg will be going up to 60mg in 2 days. I take this in addition to 150mg per day of wellbutrin and this has helped every aspect of my life already!!!!!! I LOVE IT! F 34 5 days
5/8/2007
 5  Fibromyalgia Good Side effects -- Weight loss(reduced desire to snack), reduced inflamation in ankle, increased sex drive, Bad Side effects -- nausea and insomnia, started taking pill in morning instead of at night I took Cymbalta about 1 1/2 months, went off of it due to nausea, THEN I noticed decrease in appetite, especially for snacks, and increased sex drive. Have gone back on Cymbalta taking it every other day, because of the weight loss benefit. :-) F 50 3 months
5/29/2007
 5  depression F 36 4 months
6/20/2007
 5  Severe Depression absolutely none I had been crying non stop for about a month. Although I was on Zoloft, it was no longer working for me. My doctor prescribed Cymbalta and I had IMMEDIATE results. I woke up the next morning, ready to face the world, refreshed, and smiling. It's been 6 months, and I still have no side effects and feel better than I have in years. I never even transferred up to the 60 mg pills that they suggest. The 30 mg pills work just great for me. I'm a believer! F 48 6 months
7/25/2007
 5  Severe depression-anxiety-stress At first, starting with the 30 mg, the side effects were awful. Severe dizziness, diarrhea, so bad I went to the ER. After a few days staying on the medicine, these went away. Then graduated to the 60 mg. the effects came back less severe for a couple days. Now if I miss one pill, I get foggy headed, ringing in my ears, light headed, but after I take my missed dose, about 2 hours and these go away. After a bout with severe chest pains, causing me to have a arteriogram, my doctor put me on Cymbalta for the severe depression, anxiety and stress. So far, I have had to stop taking it 1 time and that is when the real problematic side effects kicked in. Major crying, of course the depression, anxiety came back. My doctor put me back on it immediately. My friends at work even stated that if I can't afford to get it refilled, let them know and they would be glad to pay for it. They don't like me when I don't have my Cymbalta. (My HAPPY PILL) This is a wonder drug for me. It hasn't solved all my problems, but it has helped me tremendously!! F 41 2.5 years
9/20/2007
 5  Depression None I took zoloft for years but was having a lot of depression and felt really spacy. Switched to Cybalta and I am 100% better. Few episodes of depression and I don't feel so spacy and numb. It gives me hope that one day I can get off these drugs all together. F 55 8 months
6/1/2007
 5  Depression - sadness - Shldr pain day one I had this unbelieveable nausea - this is day 3 taking it and just have not much of an appetite. I read this blog and was concerned, but went ahead as everyone reacts differently. I am taking 20mg once a day for one week, then up to 40mg after that. I have noticed my moods are better already, I feel more awake. I am taking this with Lunesta and feel like I have found my perfect cure, I am sleeping, and everything is so much better! It's early days - so we will see. I will post again in 2 weeks. Anyone considering taking this should give it a shot - it's worth it. Due to a car accident for 4 months I have been on every narcotic known to man kind. I stopped cold turkey taking all narcotics and this has helped me with that too.. and the pain is actually better from Cymbalta than all the powerful narcotics and muscle relaxers. F 36 2 days
4/13/2007
 5  Anxiety/Depression/Bi-polar - None - I have been on Cymbalta for two day's and have had no side effects. I feel great! I can say that this medicine really works effectivly and fast. Unlike other meds that I have taken in the past (and trust me, I have taken more then you can image) I felt it working within and hour or two after taking the pill. My doctor has me on 30mg for one week and then 60mg from there on. Last night I slept GREAT! I didn't wake up nor have night sweats. This morning when I woke up for work I was in a great mode and that is unusual for me. Two day's ago I was reading all of your comments aboout the side effect to Cymbalata and I was really scared and almost didn't fill the prescriptiong but then thought to myself, I have been in more pain then this so what the hell and give it a try because everyone is different and I am sure it has done more good then bad. Everyone needs to keep in mind that you are going to hear more form people who have a complaint about something then the people who don't. F 28 2 days
6/5/2007
 5  depression and OCD VERy very slight twtch in my hand or arm sometimes. Does not happen much and is not noticable. I was very depresed and suicidal. I was on other medications but found that Cymbalta works better that anything I have taken. and it has proven to keep me stable. I have been on it for a year now. F 44 1 years
6/19/2007
 5  depression and panic attacks i noticed that i sweat quite a bit at night while asleep, i had a dry mouth for the first month, i lost 20 pounds in about 2 months because i wasn't ever hungry (i'm not complaining about that...) and DO NOT ever not take more than 2 or 3 days. the jolts and zaps throughout the body are incredibly uncomfortable and it makes you very, very cranky. oh! and if you drink alcohol, you won't remember a thing about the night and you will act like a jacka**. i had to lower my amount of consumption to keep straight. other than those small side effects, i reccommend cymbalta for anyone with depression. i absolutely adore it. F 30 5 months
4/12/2007
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 5  depression and panic attacks i noticed that i sweat quite a bit at night while asleep, i had a dry mouth for the first month, i lost 20 pounds in about 2 months because i wasn't ever hungry (i'm not complaining about that...) and DO NOT ever not take more than 2 or 3 days. the jolts and zaps throughout the body are incredibly uncomfortable and it makes you very, very cranky. other than those small side effects, i reccommend cymbalta for anyone with depression. i absolutely adore it. F 30 5 months
4/12/2007
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 5  depression As a psych.; amazing and immediate recovery from depression but I agree with many here that you sacrifice sleep and in my case, rapid weight gain. Once you are stabilized, it's most important to get counseling. The most effective treatment is still cognitive behavioral. F 45 1.5 years
6/4/2006

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