CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  depression awful night sweats to the point where i am drenched I started out with Wellbutrin and lost 30 lbs, was never hungry. I liked the energy factor but it still wasn't doing much for depression. Starting taking cymbalta, and have gained 20 lbs since and for some reason can't get rid of it. Very upset because I really do like the drug. May look into something else. F 25 4 months
1/28/2007
 5  Anxiety & Depression Could not sleep the first week 30mg - it gave me an abudance of energy and lifted my mood. Lost 15lbs in two weeks which is always a good thing. I am much happier and the stress and anxiety is in control. This drug has been great for me as I have taken others and could not function from day to day as other anti-depressants made me sub-human or sleep 14hours of a 24hour day. Just find the one that is right for you F 37 6 days
6/8/2006
 5  Anxiety Loss of appetite, vivid dreams I feel great. Due to my loss of appetite I now think about things before I eat them and have acquired healtheir eating habits. The first few weeks were tough (getting adjusted) but now that I am starting to see and live with the benefits I am glad I stuck with it. F 26 5 weeks
1/25/2007
 5  migrane prevention constipation, dry mouth, loss of appitite, increase sex drive, teeth grinding, hard to fall asleep and wake up alot during the night It's too early to tell if the medicine will prevent my migranes but so far it has given me more engry. Which is awesome b/c my other meds made me tired all day. The constipation went away after one week. I already grined my teeth but it has increased since taking cymbalta. My sex drive has actually increased but harder to orgasm. Hopefully my migranes will become fewer or not at all. F 25 2 weeks
1/8/2007
 5  Severe Depression (PPD),anxiety... First few days had a cloudy mind (took around 5 pm). I was on 30 mg for a month then went up to 60 mg. I take in the mornings now and usually get stomach cramps about 30 min. after I take it-but lasts for 10 min. Nothing worse than bad menstral cramping really. Night waking and sweats here and there but not sure if it's the medicine really. Loss of appetite also but not too severe. My anxiety is nearly GONE. Depression GONE! I go out and DO THINGS NOW!!!! I had a vomit phobia before and I dealt w/ my two kids and husband throwing up this month and I didn't freak out or run away. I think CYMPBALTA has SAVED MY LIFE!! REALLY! I love it and I was the kind of person that was against anti depressants. I forced myself to stick w/ this and I have NO REGRETS! I'm HAPPY! I LOVE LIFE!!!!!!! F 32 3 months
1/9/2007
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 5  major depression sweating the only thing that gets really irritating is the hot flushes, guess they'll keep me warm in winter though! F 43 8 months
3/22/2007
 5  major depression Initially had some increased sweating and fogginess. During switch from Zoloft, there were some really bad days. It seemed that there were moments that showed promise and others that were very dark. Initial weight loss. Despite the fact that I now weigh more than ever before in my life, I am feeling so good otherwise that I will take chubby and happy any day oever thin and miserable. I have my whole life back and Cymbalta had a lot to do with it. No sex problems, sweating is gone. I do have trouble deciding when I am no longer hungry. Cymbalta saved my life. F 47 8 months
1/12/2007
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 5  Fibromyalgia dry mouth, increased sweating It's like a miracle drug for me! Very little pain if any, more alert, more energy, increased sex drive, No more IBS, decreased appetite and some weight loss. I love this drug. I just wish it worked for everybody! F 46 3 months
1/8/2007
 5  post-partum anxiety jittery, dry mouth, feels like a 24-hour steady rush of energy, wake up several times a night, yawning that causes a tightness in my throat and makes my ears need to pop. after 1st baby had to take effexor, worked great, but husband didn't like me on it...i am not a worrisome person, very laid back, but the physical feelings of panic or "weird feelings" in my head/dizziness would make me worry...especially when driving. Now listening to attacking anxiety program, works great! Cymbalta is for short term, hope to be off of it by December! F 27 9 days
7/23/2006
 5  mild depression I was a bit spacy my first few days, felt like I was walking on a cloud. Some constipation. Had insomnia the first week, but then started taking it in the morning and can now sleep fine. The mood lift is worth any of these slight effects. I have lost seven pounds, (great for me) while i have been on this. I lost my desire to drink alcohol as much. Also, it has helped me tremendously with my urinary incontinence problem. All in all, a miracle drug. I felt myself being more patient with my kids and a lot happier. F 40 5 weeks
7/22/2006
 5  gad, mild depression nausea and fatigue the first week at 30mg, but went away during next week of 60mg. Nervous energy. Worked great on depression. Waiting for it to kick in fully for anxiety. F 38 3 months
7/24/2006
 5  long term depression-over 10 years Terrible night sweating (I need a towel in the middle of the night) has caused loss of sleep problems for me and my spouse. Also, problems with acid reflux that sometimes feels like chest pain. No information on whether these side effects will go away. This is the best antidepressant I have ever used--and I have used dozens alone and in combinations concurrent with psychotherapy. Currently, I take 40 mg Cymbalta plus 300mg Wellbutrin daily. Inability to orgasm on all other drugs is less of a problem on Cymbalta, although still usually happens. Unfortunately, I have not lost the 15 extra pounds from Lexapro! F 54 3 months
7/27/2006
 5  depressiona and anxiety initial dizziness and nausea and inability to reach orgasm, weight loss Now- after three months still difficulty reaching orgasm but better, night sweats (soaking), and nightmares/vivid dreams. I have been happy with this medication so far. The side effects aren't fun, but overall my quality of life and modivation for life has increased- which I think is worth it! F 27 3 months
8/2/2006
 5  mild depression/stress Very briefly-foggy headed, very mild nausea. Excessive sweating during first few days. Some insomnia at first, but switched to AM dosage and that relieved that. I have to agree that once I got over feeling a bit 'weird' for the first few days, and sweating a bit, I feel like the old me is back! Pre-stress ME! :) I have MUCH more patience with my children. I can focus better. I feel happy again. I feel no side effects at this point, 15 days into a 30mg dose daily. I hope not to be on it long, but am thankful for something to pull me through whatever it was I was going through. F 36 15 days
8/3/2006
 5  depression and chronic pain initially: sweating, tiredness, foggy thinking, lost 8 pounds, slow to orgasm; after two months, just slow to orgasm. This is the SEVENTH antidepressant I've tried in the last 16 years and the FIRST that has truly alleviated my depression and chronic pain. In a nutshell: I'm much happier, far more productive, and a better wife, mother, sister, daughter, and friend. I want to live life rather than retreat from it. (Posted Summer 2006) F 41 3 months
7/26/2006
 5  neuropothy initial- sleepiness, lightheadedness, loss of appitite. coming off of this is a NIGHTMARE, i would recommend weening yourself down off of it, cold turkey will make you seriously want to kill someone. this is my second time being perscribed cymbalta, the first time i stopped taking it ONLY because my insurance no longer covered it. let me tell you, for me--this drug is HEAVENSENT. i was miserable before i started taking it, excrutiating pain down my left hip and leg, tried everything--this was the ONLY thing that worked and it started working immediately. i've been on it again now for 3 days and i can say that the worst part of this drug is coming off of it or going onto it. if you stick it out--things get SO MUCH BETTER. F 25 4 months
3/14/2007
 5  depression 1st week--sweaty palms, anxiety, sleeplessnes, decreased appetite 2nd week--less anxiety but still have decreased appetite I feel more focused and less anxious about life in general. I have only been taking Cymbalta for 12 days and will have to see how it goes in the next month. This is the only antideppresant that I have ever taken so I am not sure what to expect. I do have a sunnier outlook though. Sex is still great- no bad side effects there! I did get a urinary tract infection-not common with me. Has anyone else experienced a UTI? F 49 12 days
2/1/2007
 5  low back pain constipation I was in a bad car accident and hurt my low back (L-5) and had undergone all kinds of injections, etc to get out of pain. My dr suggested Cymbalta. I was on in for 6 weeks and told my dr it was "a miracle drug." It was the first time I was out of pain in 4 years. Then, just as quickly, the pain came back. My dr said that he had other patients who had experienced the same response. Those of you on it for a month or so, good luck, I hope that it keeps you out of pain. I wish that it still worked for me. F 49 4 months
3/14/2007
 5  depression fibromialgia hot flashes Wonderful less pain less flashes less depression. Not all medcine works for everyone don't give up try something else. I also use suplements. Balance is the key. F 56 3 months
10/15/2008
 5  Anxiety Always sick to my stomach. Very tired. That could be from working third shift to. I started feeling better with in a couple days except for the side effect. I have to take my medicine in the pm or I cant sleep good. I feel like I have more energy to do thing with my family. I am really happy to be feeling like my old self . F 29 2.5 weeks
10/7/2008
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