CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  chronic facial pain Gesichtsschmerz loss of concentration, irregular sleep, sweating in sleep, trembling fingers, hair loss, different sense of taste, less appetite, less intense feelings The medicine didn't make the pain any better, though I'm taking 120 mg/d for two month now. I think I will stop taking Cymbalta, as it affects my studies at university. Since I'm on the high dosage I have severe problems thinking clearly and remembering things. I cant't say much about the effects of Cymbalta in treatment of depression, but I wouldn't recommend it for treatment of headache/facial pain. F 26 6 months
6/2/2006
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 2  depression on my fifth day lethargic, foggy feeling, diconnected, hard to focus. I am not sure what to do about this-I was sick 2.5 days last week, and thought I had the flu, but now I am wondering if it is the is not this cymbalta..... F 39 5 days
12/4/2006
 2  depression on my fifth day lethargic, foggy feeling, diconnected, hard to focus,my eyes feel like they have a film over them I am not sure what to do about this-I was sick 2.5 days last week, and thought I had the flu, but now I am wondering if it is the is not this cymbalta..... F 39 5 days
12/4/2006
 2  Migraines Constipation Restless sleep Found no change in having migraines when taking this medication, but did have a weight gain. F 51 5 months
5/29/2006
 2  Depression Fatigue, extreme changes in body temperature (hot to cold), slight headache, insomnia, agitation and anxiousness, fidgeting, food tasting odd and loss of concentration. The side effects are worse than the benefits. I decided to stop taking the drug as I made me feel worse than I did before I took it. I was not prepared to endure the side effects for 2-4 weeks to see whether the drug would work or not. I can't see how it can be an anti-depressant when some of the side effects are depressive thoughts and actions. F 21 1 days
4/6/2007
 2  Depressed w/ Chronic neck condition Severly damaging to the stomach lining. No ability what so ever to orgasm, Vomiting for over 2 weeks in a row. Night sweats, vivid dreams, hot flashes, bad. I want to share my story with Cymbalta, because I read alot of the reveiws. The first thing, some drugs DO work for some people. We need to look at the age and sex of an individual, and their problems. I do beleive that the DR knows best, but no one knows your body like you. I took Cymbalta, I LOVED IT. LOVED IT. I felt great. No more crying, virtually no more pain, I suffer with a great deal of pain everyday, and have been taking also narcotic pain meds, that still didn't work as well as Cymbalta. But, I started noticing problems with my digestion. The IBS is normal when taking med's like this, so that never was a real issue, but I always had like a rock feeling in my esophagus, and stomach was bloated adn aching. Then the vomiting started. I cold turkey stopped Cymbalta, needless to say I ran out of my narcotics at the same time, and BAM! It was awfull. Any body who may have had an addiction can understand, I went through the worst thing I have ever been through, a chemica F 29 4 months
4/5/2007
 2  Severe Depression Almost constant flatulence/bloating; infrequent heart palpitations; night sweats at first; no apparent sexual side-effects; extreme headache/dizziness upon missing a dose; flu-like symptoms; chronic aches and pains As with all other meds I have tried, Cymbalta seemed to work great in the beginning except for some initial dizziness/nausea. After two years, I think the effectiveness has worn off. I have had severe insomnia for the last three months and cannot get a night's sleep without taking Lunesta. I am trying to get an appointment with a psychiatrist since my previous one retired and there are waiting lists for the other two in town. I am happy that this medication has worked well for some, but I am now nearly as depressed as I was before I began taking medication 20 years ago. If you decide to take this drug, I would recommend keeping a "side-effect" journal; I wish I had started one two years ago. It's so hard to know what might be a side-effect and what might be something else. F 43 2 years
11/30/2006
 2  Osteo-Arthritis Pain Relief Headaches, Extreme tireness during the day, Vision changed -fuzziness/halos around lights, joint pain, sharp/jabbing stabs of pain Initially, I started Cymbalta at 60 mg/1 week then progressed to 120 mg. I was told this might help with my osteoarthritis pain. I did feel emotionally better initially but if I missed one morning's dose, I was extremely emotionally and down by the end of the day. I took Prozac 20 mg. prior to this for about 5 years and had no side effects. Cymbalta didn't help with the pain and I am experiencing more pain as I am weaning myself off 120=>60=>30mg. I am experiencing other side effects such as roaming joint aches, headaches, sharp stabbing/jabbing pain in hands/feet. I am menopausal and having more migraines. I have also been taking HRT for about 8 months with the cybalta. My doctor thought this drug might help with the pain and headaches but it definitely did not. If fact, I feel new symptoms such as being chronically tired each morning about 7:30-8:30 while at work and there is no reduction of incidence of headaches. I have also tried Rozerem for last two days with Cymbalt F 50 1.5 months
10/17/2008
 2  depression. anxiety, panic attacks. loss of appetite. shortened attention span. since i started taking cymbalta i've found that no food sounds desirable and i keep waking up in the middle of the night. i have no sex drive. i've even heard voices, though, i'm not really sure if that's something that goes along with taking this medication. F 18 1 weeks
10/21/2008
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 2  depression/ocd EXTREME sweating, flat feeling, anger, halo around head feeling. I thought this was supposed to help depression, I think it made it worse! After reading the other posts here, I can now see what I thought was signs of depression is actually side effects of the drug. I think Cymbalta has made me extremely angry at everyone and has made my obsessive thoughts worse! F 6 months
10/21/2008
 2  borderlin/bpd, severe depression heartburn, bad, took 2 prilosec to get it under control. Terrible joint pain that I have never had before, in my ankles, knees, feet, sometimes I get up to walk and feel like i'm gonna fall down. Terrible constipation. Has been so-so for helping my migranes, but I see a chiropractor for that and if i go regularly my migranes are greatly decreased. At least 30 lb. weight gain. All I wanna do is sleep. Maybe right for some, cause everyone is different, but I want off this ride. F 38 5 months
10/22/2008
 2  Anxiety, depression First day: tingling feeling in my head, almost like shivers down my spine, but in my head. Second day: total insomnia. I thought since this was a newer drug, there might be fewer side effects. But the total insomnia I experienced was the worst of all meds I have taken. Even after taking it in the morning I could not sleep at night. It was horrible. I will not be taking it anymore. F 30 2 days
10/19/2008
 2  severe long trm dep w/min bp hard transition from lexapro then noticed improved mood. But sick all the time from insomnia and also physically feel like I have the flu. Seems like the anti depressive effect was very very temporary with me and now just feel like a total mess. This drug has not been studied on nearly enough people. We are allowing ourselves to be the guinie pigs. F 46 4 weeks
10/2/2006
 2  Depression, Stress, Panic attacks Nausea, mild disorientation, full loss of apetite, flu-like symptoms, zombie-like feeling,tightness in the jaw, constant forceful yawning, and EARLY morning insomnia This drug helped me with my daily massive headaches, and body pain. It helped me not care (about anything),it also eased my depression. BUT later that first day,as soon as i started working out at the gym i got a splitting headache and felt as if i was going to explode in my head. Later that night i woke up at 3am and couldn't sleep. i had this weird feeling ..something like i know im here, but when i looked at my body i wasn't sure, i didnt care to move my limbs if i stayed still...i cant explain it i was so spaced out, it made me more anxious because i didnt reognize the way my soul felt. I wanted to laugh and enjoy, but i didn't have the spark*--this was yesterday. and im not very sure which is worse,mild depression and panic attacks or this "medication"(depression for me is pain coming from my mind, and the pill felt like a mask on my mind and pain in my quality of life) . Cymbalta in my experience was like legal low-dose speed.I think i will try group therapy, red bull,a F 19 1 days
10/3/2008
 2  mainly antideprecion swithced from effexor due to the major benefits that cymbalta claims helps with neuropathic pain. i have just been diagnosed with chronic pain syndrome that was diagnoed as fibromyalgia for a year. i told thie dr that the cymbalta was too much effects or safe neuronic the average side efects of any major drug stopped suddenly. bad moods relapced to can be used as a pain management drug but doesnt work that wll. my stepson commited suicide from this drug. it needs to be monitored for the first week or so. F 31 9 months
10/6/2008
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 2  depression/anger can't stop yawning, wake up in the middle of the night, am so tired during the day... like a zombie i've not even been taking it for a week but i dont know if i can deal with the side effects. im exausted during the day, waking up in the night... i've tried taking it in the am and pm and its all the same. totally constipated, i mean big time... anyone else had these issues? have they gotten better? im worried, i can't go on like this for long F 24 5 days
10/15/2008
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 2  anxiety and chronic back pain sleeplessness, shaking I began taking this drug for treatment of anxiety and chronic back pain. Before treatment I was finding myself having anxiety attacks and mood swings that were not healthy for myself or my 4 year old toddler. I had moments of rage when I thought I could just explode...I would become angry and it would grow intensely and quickly. So, after getting on Cymbalta I truly did notice it was helping and other than the shaking and insomnia it was worth it to me...but then!!!! I had to stop taking it abruptly when I couldn't afford it and HELL SET IN!!! I began to have "electric impulses" mainly in my hands and fingertips and they were the worst in the morning. It happened when I'd get up...I'd feel strange, almost unbalanced, then the electrical shock feeling would kick in. It was really scary and there was nothing that could be done about it. It lasted for weeks. It wasn't until later and after I'd stopped taking it that my migraines returned in such frequency that it scared me...in F 28 6 months
10/7/2008
 2  severe depression Triggered extreme rapid cycling. The good thing I can say about this med is that it helped determine for sure that I have bipolar disorder. I went into severe rapid cycling, mania, hypomania, severe suicidal depression ... it was terrible. I am coming off it now and already see a difference. DO NOT TAKE IF YOU ARE BIPOLAR WITHOUT DISCUSSING THIS WITH A PSYCHIATRIST!!! F 22 3 months
3/21/2007
 2  anxiety, depression 20 mg. No nausea, but a little constipation at first. Mild headaches from time to time (top of head). Took in a.m., and by p.m. I could often feel my heart pounding. Did not gain weight, but could not lose in spite of diet & exercise. Initially I felt energetic and had a bounce in my step. Felt calmer and found it much easier to make decisions. I didn't worry so much about making mistakes. However, it really didn't bother me that much if things didn't get done. Found I could no longer multi-task, and everything seemed to take longer to accomplish. Slept really well, but seemed to require more sleep, and had a hard time getting up. Never shed a single tear while on this med. Over time I started feeling more and more light-headed, and my legs felt weighted down, sometimes painful. I could not get my heart rate up while using the eliptical at the gym, and would cut my walks short because of fatigue. Withdrawal took almost a month. Headaches, light-headedness, problems with my eyes (slight delay), and achy chest and legs. Kept feeling like I was getting a urinary tract infection. I think I was retaining water because my clothes seem to fit better now that I am off the med. Be extremely careful, that's all I can say. This med is truly a double-edged sword. Do not start it unless you plan to take it forever, because it is very difficult to get it out of your system. I FINALLY feel good again, but was terrified that the med had done some irreparable damage to my brain. F 55 5 months
4/22/2007
 2  Complex Regional pain syndrome severe Constipation, Urine retention, no libio, It seemed to numb all my bodily functions. F 37
3/15/2007

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