CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Chronic pain, depression Severe stomach cramps, upset stomach, dizziness, spacey. It's been horrible! I have tried a lot of different depression meds, am taking Lortab for pain 2xs a day. I really hoped this would work so I could get off narcotics for pain but I would rather take the Lortab than this garbage. This med should never have been approved by FDA. F 44 1 days
30mg
6/5/2013
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 1  diabetic neuropthy pain absolutly the worst med ive ever taken,,i was a zombie,,in pain constanly,,could not get off a chair or raise to my feet,walked with a cane,,couldnt roll over in bed,,had to get out and back in,my hubby had to lift my legs onto bed,,i was ready for a psyc hospital,,it was terrible,,,, F 77 5 months
30 1X day
2/8/2013
 1  PTSD anxiety and Bi-polar nausea, vomiting, fainting, dizziness, fatigue, rash, phantom smells, loss of all motivation, loss of appetite, irritable, extreme sweats and hot flushes quickly changing to shivering flu like symptoms, My illness made my life uncomfortable. the drug made it intolerable. coming off the drug made my life not worth living and was close to ending it. the withdrawal (even when reducing gradually) is a living hell and hell visits you in your sleep in a bloody horror movie way. I hate this drug with a passion. after being off of it for just 2 days and despite the horrifying withdrawal symptoms, my spirit and will to live returned and i actually got out of bed for the first time in 8 weeks and cooked a meal. F 50 9 weeks
60mg 1X day
2/22/2013
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 1   If you are wondering why you so quickly feel better (pain free) ask a chemist to explain to you just how close to "ecstasy"the notorious date rape drug this actually is! and the reason that it "quits working" and you have to go up in dosage after awhile is because your brain craves MORE. THIS is not a medication it is a drug, the withdrawal is worse than from heroine a DEA agent told me ! BWARE!!!! Dangerous Drug !!!! F 64 6 months
60mg 1X day
3/20/2013
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 1  fibro stomach pain and vimiting first drove to work pulled over ti puke could not open eyes dizzy couldnt drive climbed in the back of my car because i was confused just wanted to lay down clinching teeth seeing things loss of time layed in my car on side of road for 4 hours in 80 degree waether went to er over heated needing flids its now night time and i cant go to slleo still clinching teeth will not be taking it tomorow please if you try it dont drive and have some one a round some one could have rapef me i would have been able to do anything so scarry F 28 1 days
30 mg 1X day
5/17/2013
 1  Pain Extremely thirsty day 1 couldn't drink enough water. Could not sleep and was severely nauseated. Day 2 nausea, dry heaves, diaherrea all day long, lethargic no appetite. Day 3 nausea, diaherea lethargic and miserable. I was prescribed this drug for pain, no change in my pain at all, now feeling like crap on top of being in pain. I feel like I have a whatever, bitchy attitude not feeling like myself at all. My husband thinks I need to stop taking it because I am not myself at all. 3 days of this drug and I am done with it. Bad stuff!!!!!!! F 45 3 days
30mg 1X day
5/27/2013
 1  Back pain I took this drug before and stopped. I resumed it for three days and am nauseous, severe headache, fast heartbeat, unable to sleep. Severe muscle cramping in legs and arms. I am stopping it and hope to feel better F 54 3 days
60
9/26/2012
 1  Depression/Back pain Nausea, Brain zaps, SEVERE WEIGHT GAIN 60lbs This drug is HELL. If I missed a dose by a few hours, the side effects would start. Brain fog and brain zaps are horrible!! Even more difficult to stop the drug. It's like they want you to be addicted, so you can stay a lifelong customer! It did absolutely nothing for pain. It worked wonders for my depression at first, but since I gained so much weight I was more depressed than when I started. You just keep gaining no matter what you do! As soon as I got off cymbalta I lost 30lbs instantly without doing anything. F 29 18 months
60mg 1X day
10/13/2012
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 1  Anxiety I took one pill on a Saturday and soon felt stoned out of my mind. Had no strength to get up or do anything but sleep. I very nearly slept an entire weekend away. My knees and hip both hurt afterward. These plagued me until Monday afternoon. Sticking with ativan as needed and seeing a therapist. Will never touch that medicine again. F 40 1 days
30mg
10/16/2012
 1  MS and Ovarian Cancer Pain Sick to my stomach. Headache, anxiety and felt bloated all the time. I would also have bouts of sweating. Gave it a month and then stopped using it. I was given this to take daily. I have Lortab for serious pain but this was to help in between with daily pain I suffer with. I do not use Lortab very much and this was to be something that would sort of help me daily. This drug was terrible. Would NOT advise taking it. It did nothing for pain. It mostly just made me sick. Quick after giving it a solid 30 day try. When I don't want to use the Lortab. I do much better taking Motrin or an older medication called Ketoprofen. F 38 30 days
60 1X day
10/20/2012
 1   I took one Pill Tuesday evening. I felt Stoned, Drunk, Confussed, Dizzy, my Heart is fluttering and I keep having sharp pain in Back and Legs, short of Breath. It is Thursday and still feeling the effects from 1 pill F 40 1 days
30 MH
10/18/2012
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 1  lower back pain nausea,vomiting,stomach pain,constant sweating,memory loss,mind racing,migraines,panic attacks,fatigue,brain zaps.numbness and tingling on right side of body,moodiness,depression,rage,crying jags,lethargic. I weened myself off of Cymbalta and have suffered terribly with withdrawals. F 51 2 years
60 MG. 1X day
9/18/2012
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 1  Depression and anxiety Almost died. Eli Lilly told doctor that I could drop dead at any moment. I had no history of heart trouble. Taking 100mg. Serotonin toxicity? Took 4 months to come off it. List of side effects during withdrawal is lengthy. Extremely unpleasant and at times frightening. Too many to put down here. A couple of side effects have no yet disappeared even after stopping Cymbalta over 4 months ago. My personality changed while I was on Cymbalta but has returned to 'normal'. Now I am embarrased over some earlier behaviour. Also my brain has cleared (not confused as it was when doctor was warned of likely imminent death) and my memory vastly improved. I am amazed that I seem to have escaped. However, at night I am usually sweating around neck and down chest despite the fact that it has been winter. I find that I can't control my environment to ensure that I am neither too hot nor too cold. There seems to be virtually no margin, no comfort zone. I will either be too hot or almost immediately feeling chilly no matter what I do. I do not have a temperature. My husband can be wearing a coat and beanie while I am in a sleveless cotton nightdress and have the window open. It is not menopausal. That was over about 10 years ago with no side effects (no hot flushes etc.) F 62 500 days
1X day
9/9/2012
 1  Mild depression/anxiety Switched to Cymbalta after Pharmacy screwed up and said Insurance no longer covered Lexapro (they were wrong). Cymbalta through me into a the DEEPEST pit of depression that I have ever experienced and hope to NEVER experience in my life again! This was 2 years ago! After discovering The mistake the Pharmacy made....I was promptly switched back to Lexapro and Have been so much better and feel NORMAL!!!! F 45 2 months
1X day
4/22/2013
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 1  Depression/Anxiety Always tired, yawned all the time. Constipated. No sexual desires at all. F 34 6 months
60 MG
9/22/2012
 1  Fibromyalgia Weight gain F 58 3 years
60 1X day
8/26/2012
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 1  depression and pain you have no idea how bad this drug is until your pharmacy needs to call your doctor and you are without it for just ONE day and go into full blown withdrawals - or when you attempt to get off it. You will start counting the pellets inside the capsule to reduce the dosage to get off this drug. HIGHLY addictive. You don't realize it until you want off... nightmare medication unless you are on it forever and good luck with the long term side effects... research!! F 50
60 mg 1X day
7/25/2012
 1  minor depression, migraines The cymbalta kicked off anxiety and insomnia big time. It was too stimulating for me. Went off and now using viibryd F 31 2 months
60 mg
8/15/2012
 1  Trigeminal Nueralgia Extreme body sweats, all over drenching sweats. Ringing in the ears. Worked the first couple of weeks. went from 30mg to 60mg. It all went downhill from there. Total body drenching sweats hourly. restless in late night and only really got to sleep at 3pm. Kids would be up and going at 7:00am. so only 4 hours of sleep for me argh. weened off and stopped taking altogether from dr. Nightmares, vivid sleep walking/talking episodes. muscle spasasms, deafing ringing in the ears. Buring sensations on side of the face and ear. I had asked about side effects of withdrawl and dr's siad just minimal. I hope this is not minimal... F 43 6 months
60mg 1X day
8/11/2012
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 1  back pain Weight gain, unrelenting nausea, sweating, drowsiness. Most important: it did little or nothing for my back pain. My Dr. wanted me to try this drug rather than using chronic vicodin and I agreed because I respect his opinion. My pain became unbearable and all I was offered was Cymbalta; not even a good placebo. After 2 months on Cymbalta I asked my Dr: do you even care about my back pain? Do you think that Vicodin is in any way, shape or form a "worse" drug than Cymbalta? Vicodin works and has few side-effects, the Cymbalta side-effects are terrible and it doesn't work; and stopping it is worse than stopping Vicodin. After a little badgering, he admitted that Cymbalta was a bad choice and I got my 6 month rx for Vicodin..that was 4 months ago, pain pretty much gone and I only use it prn. Nobody should be prescribed Cymbalta for chronic pain, nobody. F 50 60 days
60 1X day
8/1/2012

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