CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  pain, fibromyalgia had dry mouth, constipation, horible tremors and double vision, and confusion F 85 21 days
1/19/2009
 1  depression Extreme fatige,sweating,nightmares and that was just the beginning.The thoughts of suicide were overwhelming and it made me feel a horrible despair.Mood swings,extreme anger,leg pain just to name a few. I didnt take cymbalta for long because it was turning me into a worse basket case than I already was. One thing I did experience when trying to get off it was mood swings. Some of which were very angry outbursts,an anger I never felt before.Lost the love of my life because of it. Now taking 100 mg. of Zoloft and feeling so much better. I would not recommend cymbalta to anyone. F 46 2 months
2/9/2009
 1  depression and arthritis pain In the beginning, extreme nausea, digestive upsets..got better but never went away completely. Horrid hot flashes and sweating at night. I have tried almost every antidepressant and this is BY FAR the worst. My mood improved but I became "flat" and became a recluse. My legs became restless and felt tight however the drugs worked well for pain for the most past. Going off this drug was horrible. I took prozac instead of the cymbalta and that helped alot. The nausea resumed however for nearly a week. The medicine is very pricy and prozac is $5 generic. I had been on prozac 15 years with mild side effects...I will stick with that. Check out the other options before you chose cymbalta. F 43 4 months
1/30/2009
 1  depression/chronic back pain Mania, anger compulsive behavior. Diminished sex drive. Severe constipation not even responsive to high doses of laxatives. Reclusive desires. Compulsive drinking, smoking, shopping. Quit upon recognition of all of these bad sideffects. Cut from 120 to 60 to 60 every three days to none.Anxious to be off took only three weeks for withdrawal. Horrible withdrawal symptoms...It still feels like a brick is in my head, but glad to be free from this drug F 45 8 months
1/30/2009
 1  Depression/fibromyalgia Dizziness, weakness, extreme pain, anxiety, depression worsened. I was on Cymbalta for about six months, last year. The side effects crept up slowly, at first I thought it was helping the depression and I'd noticed a lessening of my fibro pain, but the longer I took it the worse my dizziness became, I started getting weaker, couldn't walk more then 50 feet without needing to rest and almost collapsing. Then the fibro pain started getting worse and my depression worsened to the point of becoming suidicidal. F 62 180 days
1/27/2009
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 1  depression/anxiety insomnia, anxiety, racing heart, racing thoughts, headache, nausea, clouded thinking, heartburn I have been on this medication for about a year and it helped tremendously at first. Now I am having SEVERE anxiety, nausea and headaches. I am going to begin tapering off of this tonight now that I know to remove seven beads a day. Will let you know how it goes. F 31 1 years
1/31/2009
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 1  Depression Numbness, tingling, brain "zaps", headaches, HUGE weight gain, tremors DO NOT let your doctor put you on a high dose....I was on 120 mg daily and I gained over 30 pounds in the 6 months I was on this. Numbness, tingling, and brain zaps if I missed a dose. Took myself off when my doctor suggested I go on a blood pressure med to reduce the tremors. This drug should be OFF THE MARKET F 29 6 months
2/2/2009
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 1  anxiety/depression This is day 5 since I stopped the 30mg cymbalta and i must say..i feel TERRIBLE! feel like i have the flu..horrible headache, can't sleep..body is aching something terrible..but i will ride it out..i will NEVER take another pill!! F 31 1.5 years
2/6/2009
 1  Depression Suicidal, zero energy, constant crying, spaced out. Fire and rescue literally had to come to my home and take me to the emergency room. I COULD NOT FUNCTION!!!!!!!!!!!! Terrible, terrible experience! F 49 3 months
4/23/2008
 1  anxiety extreme weight gain, intense migraines, an aura around everything similar to begining migraine, muscle spasms. I am still not off of it everytime I try I get extreme dizziness, like being on a double loop rollercoaster all day, feeling like I just might pass out. Is is also very expensive. F 42 5 months
4/28/2008
 1  Depression/Fibromyalgia Sleepy but unable to sleep, severe IBS flare w/intense cramping, zombie-like Absolutely horrible for me. Always resisted it but drs talked me into it to replenish serotonin due to prolonged, intense stress caused by chronic pain, PTSD, etc. This drug was a nightmare. I felt so tired but when I laid down, I couldn't sleep, racing thoughts, agitation. When I was up & about, I felt like I couldn't wake up from a bad dream. Felt like I was watching my life instead of living. Then the cramps started. White knuckle intestinal kind. I normally have severe IBS-C but ended up with D. Took days to recover. I'm sad this didn't work out. But I am glad that I only took the 30 mg tablet instead of the 60 mg the rheum. gave me. Evidently there is supposed to be a step-up period but some drs are misinformed. I think the company ought to provide much, much lower doses to start with. (There's a 20mg but evidently that's not the standard sample handed out). F 50 1 days
11/4/2008
 1  Pain and depression weight gain, lethargic, night sweats. THE WITHDRAWELS ARE TERRIBLE AND COULD RUIN YOUR LIFE!!!!!! I have been withdrawing off Cybalta for 3 weeks. I used prozac to get off it, which was better than weaning or cold turket for me. I have only allowed myself to drive the past couple of day. The brain zaps, aggitation are a little less each day and I didn't cry yesterday and so far today I am free of tears. I researched the withdrawal thing and several people wrote, "I am still on it because I can't get off of it" If I had children or worked outside of the home, I would still be on this stuff. When I asked my doctor about it and told him that when I was late for my dose that I got "Paxil Head" and he wanted to change my percription to another med in the same family and did not believe me , but humored me with prozac, which I only took one . The prozac leaves your body slower and helps make the first day a little more bearable. Please read these warnings, these side effect could very easily mistaken for depression and mental illness. F 53 3 years
4/18/2008
 1  Depression & Fibro Apathy, mean-spirited thinking, headaches, lack of focus, couldn't care less attitude, insomnia, constipation. Second time trying this. Not for me. I was so annoyed at my dog for PANTING in the middle of the night, I actually turned him out of the house. He could have been killed or lost. I came to my senses, got dressed, went out and found him but realized that this med was driving me to very bad decisions. I never, never intentionally put my dog in danger before, or will again. End of Cymbalta for me. Watch out on this drug. Might work for some, but beware for those it doesn't help. Gotta be something better out there. I am sick and tired of suffering to make money for the drug companies. F 55 7 days
4/15/2008
 1  Anxiety/Depression Nauseau, profuse sweating, dry mouth, can't sleep. The side effects are too much to take. I was on 60mg. per day butwhen I complained the doctor put me on 30mg. per day but I still feel awful. I throw up alot. F 37 2 months
12/4/2008
 1  depression-bi polar 2 blurry vision, then double vision, nausea, nightmares depression went away but it was not worth the severe vision problems & extreme nightmares. F 66 75 days
12/4/2008
 1  severe depression suicidal migraines, stress headaches, confusion, no sex interest, slept up to 12+ hours, chronic fatigue ^, delayed processing of information, apathetic, flat, first thought of suicide 6:57 am Do not recommend to anyone. Remember, drug companies are first and foremost out to make big bucks; cannot explain scientifically how C. works, or any other antidepressant IS NOT KNOWN. MD.s heavily use Reps. to promote their "poison" pills and the shrinks listen to them, get their "education" from them. Good luck and be careful, my dear experimenter. I am off the "stuff." F 51 5 days
11/26/2008
 1  depression and anxiety I took 15 mg and fell asleep. Woke up 4 days later. Had constipation, racing heart, nausea which lasted 2 weeeks and all this from a single dose. Just had a liver function test and enzymes have doubled. Psychiatrist is a lovely man but believes the drug reps when they say there are no side effects. F 48 1 days
11/17/2008
 1  depression, back pain, fibromyalgia agitation; hostility; suicidial thoughts; increased pain; increased depression; muscle spasams in legs and feet; dry eye; increased blood pressure; heart palpitations; increased anxiety, etc. Switched to Cymbalta because of claims that it helps with pain. Side effects were terrible. My prescribing MD assured that a second increase in dosage was needed. He believed the drug rep but not me. Finally, was able to see a board certified psychiatrist and switched to Lexapro. Huge improvement and almost instant end to leg spasams. The industry needs more honesty about Cymbalta side effects-it made my liffe a livng hell for 2 years. Wonder how much those drug reps make per year in bonuses. F 60 2 years
11/21/2008
 1  depression/anxiety Increased sweating, numbness from my tongue to my extremities, can't sleep, swollen all over, and if you look up hypothyroidism you will find everything I am going through since I have been on this horrible. It helps with the constant thoughts of worry playing over and over but it's not worth it when you wake up and you have missed some days and you are having zaps so bad if feel like your head is going to explode. I take it and I get so swollen all over and the weight gain within 6 months is amazing. I wish we could get a petition to this company who said take this drug and you will feel wonderful. They should provide everyone who is having a tough time to get off this medicine with something to help you get off from it especially with the extreme side effects that effect your day to day life. I hate it. If your doctor says to get on it please look up hypothyroidism and if you still want to take it then you have been warned. Believe me this is my second time trying to get off from it. The first time I thought I was having a heart attack so I took one and my Klonipin and within 4 hours my symptoms went away. F 39 3 years
12/14/2008
 1  Depression WEIGHT GAIN DESPITE REDUCED CALORIE INTAKE, frequent nausea, vivid dreams to the point that is difficult to wake from them, head rush that made me think I was having a stroke, disassociation, spaciness, horrible withdrawal symptoms--so NOT quit suddenly or on your own. Withdrawal similar to heroin withdrawal. THIS MEDICATION IS GOD AWFUL AND IT SHOULD BE BANNED. F 42 6 months
12/20/2008

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