CYMBALTA Reviews (DULOXETINE)

Average Rating: 2.7 (2745 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

CYMBALTA  (DULOXETINE):  Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on CYMBALTA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR CYMBALTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Fibromyalgia Chronic low grade headache, dry throat, loss of emotional feeling, nervous agitation, insomnia, drowsy, sweating. I have tried it once before. It worked great for the fibro pain but I quit after 10 tens because of all the side effects. I'll try and ride them out but be warned......anyone taking this drug......if you can't handle it the withdrawals are wicked. Wait until you start to experience brain zaps. Wish me luck. M 51 3 days
30 1X day
3/16/2015
Email
 1  for ativan withdrawal EXTREME SUICIDAL IDEATION M 48 1 days
4/8/2013
 1  Depression Night sweats, sexual dysfunction, hypomania, and others. M 29 6 months
120mg
2/21/2014
 1  muscle aches While taking this medicine all was pretty good, coming off it was horrific at best. Agressive behavior, moods going high to low, brain zaps were terrible now off this for 3 weeks and still having bad brain zaps. make this drug your last choice, if possible M 49 1.5 years
60 1X day
7/23/2013
Email
 1  Anxiety/depression Low libido, black outs, no help for depression M 42 6 months
60mg
4/3/2014
 1  fibromyalgia and back pain inability to have sex headaches nausea will not go away after being offered for 2 to 3 years M 64 2 years
90mg/30mg
5/16/2014
 1  nerve pain Made me unable to think, eliminated my motivation, could not focus, made me very tired, but couldn't sleep, them towards the end became out of sorts and felt angry for no particular reason, did NOT take care of pain!!! When Dr. took me off it, I had withdrawals like hard drugs and ended up in kidney shut down and had to go to emergency. This drug is dangerous! It made my life a disaster. Should NOT be approved for pain issues, it destroys your life! Shame of FDA and any Dr. that prescribes it for pain. M 58 9 weeks
30 mg 2X day
7/26/2014
 1   0 Heavy diarrea M 1 days
30 1X day
3/11/2016
 1  Clinical Depression Started out as "best thing since sliced bread", but brain zaps began. Been slowly weaning from it and it looks like it's going to take a while.Fish Oil (Omegas?) Seem to help with withdrawals.If talking helps then I'd love to hear from anyone. Email below here somewhere, I guess. Been on numerous SSRI's for over 10 years. This SNRI started off great, 30mg once a day for a week or so then up to 30mg 2 times a day. Nearly a month ago I noticed the "brain zaps", I guess. More like my brain was turned into ultra fine steel wool and I could hear and feel my steps at times. I could hear my eyes blink, or a squishy sound in my ears (like someone squeezing steel wool inside my ears). The sounds came along with the "mild electric jolt" feeling too, from toes to head often. Generic form I have are 6 small white pills inside the blue and white capsule. Dropped from 60mg to 30mg for several weeks. Then began removing 3 of the small white pills to take 15mg for a few weeks. Was going to remove one more to go to 10mg then one more later to take 5mg for a few weeks. As John, the Duke, Wayne says at one point in McClintock, "Ya-ta-hey". I guess it's Comanche for something, but it seems appropriate for this time. I'm on day 2 of NO Generic Cymbalta. Didn't drop it by 5's as planned. Yesterday was a good day. Today is much vertigo, zaps, steel wool sounds that come and go. Have also been having the WEIRDEST dreams. I wake up and go right back to the dream, like for a freaking commercial break! Dreams seem to go ALL night. I have sleep apnea (5'7", 160 pounds), and use my CPAP, but I'm still tired, I assume, from the dreams. Not really nightmares, like as for many I read about. Take vitamins, have for years, but also 4,000 mcg of Fish M 56 6 months
30mg 2xday
1/28/2016
 1  depression Almost immediate change in cognitive and visual perceptions Spaced, foggy thinking,altered perceptions of routine actions ie Walking felt new,talking seemed to echo within my head , anxious thoughts, extreme fatigue slept on and off for last three days since starting on 30mg only taken for 2 days . I have completely abstained from alcohol and all illegal and prescribed medications for 13 odd years before making the decision to try an anti D as my life situation is spiraling due to depression unemployment ,relationship breakdowns both intimate and family. Id had starter box for 6 months and just finally took one to see if i would feel something for the better shift. I immediately felt completely out of it ,akin to the first rush of an lsd tab, racing thoughts , mentally numb and foggy. It was in this state i picked my son up from school Even though i thought i presented normally he immediately asked " whats wrong dad you sound weird?" That's all the red flags i needed not continue down this path. If i hadnt had over a decade living with depression and anxiety non medicated i would possibly be enjoying the mental fog and body stone but i cant stand feeling this drugged. its like cymbalta immediately added itself as a complete thinking and feeling system to my brain . 3 days ago i knew i was depressed and needing to make changes to get some form of joy or happiness into my bleak mindset. I now know for me alone i prefer that than this chemical straight jacket state. I was on anti depressants for 8 years til 13 years ago They sure helped me feel better about my insane life and drinking /drugging for a while so they did "work"on one level then.. I just can't go back to feeling drugged and be ok about finding my peace of mind there.. M 49 2 days
30
2/20/2016
Email
 1  Anxiety and pain After taking it 1 day, I got very sick .. Diarrhea and upset stomach lasted 2or 3 days. Stopped taking it May try again after the shock wears off M 72 1 days
30
2/20/2016
 1  depression/fibromyalgia brain fog, loss of cognitive skills. A dumbing down effect and affect. Stopped after 30 days, now my pain is worse and I have brain ZAPS and numb fingers all day. Moody and unbearable, almost "like" looking for trouble. My opinion, stay off SSRI and NSRI's period!!! Speaking as a BN. (Baccalaureate of Nursing) M 48 30 days
3o 1X day
10/30/2016
 1  Neuropathy Started at 30 mg for a month. Minimal effects Doctor increased dosage to 60 mg seemed to help foot pain. After 6 months prescription was not refilled due to error at doctor's office, I was not informed of withdrawel issues of this med. After 48 hours I experienced extreme dizziness, brain zaps and vision problems I had no idea it was due to withdrawel from the med at the time. I realized I had best head to the emergency room that evening. Thankfully my exwife got in touch with the docotr's emergency servive a prescription was called in. I had to go to an optometrist a couple days later due to seeing color bands out of the corner of my eyes when looking to either side and floaters appeared also. The optometrist and the prescribing doctor said the visual problems were just a coincidence. I still see the floaters 24 months later. I'm trying to get off this stuff by dose reduction but every day is a challenge and very uncomfortable. I feel like my cognitive abilities have been permanently impaired. My reading and mathematical comprehension have been are degraded and I don't feel like I'm the same person I was before I started the medication. My fingers jitter so much when I write that my writing is scribbled. I experience frequent dizziness and brain zaps. My dreams are crazy and depressing and I wake up 2 or more times each night and feel tired all day. And lots of unusual sensations and frequent headaches and hand tremors. I pray I can get completely off this medication soon and get my life back on track. M 66 2 years
60mg 1X day
4/12/2016
Email
 1  Pain and depression No side effects. Has never really affected me at all positive or negative. Was off of it for a while, but never suffered side effects. I don't know why it doesn't help. It's like taken a baby aspirin. Never helped initially or current. Was off of it for a while, but never suffered side effects. I don't know why it doesn't help. It's like taking a baby aspirin. Never helped initially or current. M 3 years
60MG 2X day
4/20/2016
 1  depression/anxiety Pill "hits" like an illegal narcotic after so many minutes, felt silly and goofy the first two daysm extremely fidgety, more so than normal. Terrible tremors, up for two days straight, remembering hours later what I set out to do. Passed out cold, awoke third day to ringing ears, nausea, blurry vision, severe mood swings, as if I didn’t have enough already, and my favorite, little itchy patches that fill with seepy water and pop almost instantly while removing the entire patch of skin it was covering leaving a raw open red uncovered blister that NEOSPORIN burns if touching them ! Picture chickenpox before they scab, but pop immediately when they appear. And I HATE to tell you where some of these blisters are. Maybe about six or seven large ones around body,. No goody feeling anymore, agitated quickly, "whatever" attitude, confusion, lack of wanting to do anything, narcoleptic "fall asleep anywhwe without notice" type effects, don’t realize amount of time , sometime couple seconds once fifteen min. Doc said blisters were an allergic reaction to stop immediatelY. It's amazing how many of the posts I read the people that say it's done wonders for me and I don't care if it's addictive but these are the same people that will turn around and call a Street addict "degenerate bastards" it is amazing what Society does. The effect of alcohol is The Most Dangerous Drug according to the FDA still…because of what it does to your body and in the am HEY DOC THOSE PILLS MADE ME WAKE UP IN SOMEONES HOUSE AFTER DRIVING THATBI DONT REMEMBER, CAUSED JAUNDICE WAS HOSPITALIZED BECAUSE MY HEART VALVES EXPLODED AND ATTACHED THEMSELVES TO MY BRAIN AND IM MOTE DEPRESSED THAN EVER.....OK PATIENT, HERES AN ATTORNEY REPRESENTINF THAT DRUG, YOU DONT EVEN HAVE TO GO TO COURT THERES A SETTLEMENT FUND AVAILABLE. IT SEEMS WELL JUST HAVE TO UP YOUR DOSES. NOW ARENT YOU GLAD YOU STOPPED THOSE ILLEGAL STEEET DEMONS? amazing how more and more ailments are being treated with antidepressants so instead of actually curing the problem they're making your brain stop functioning properly for that area so you don't feel the problem. Hmm like a form of mind control? just take this pill it'll stop that feeling of guilt when we ask you to kill these people...like cattle? Think about it... M 49 4 days
60
4/20/2016
Email
 1  Depression, anxiety, Hypoglycemia, shaking, sweating, Do not take it. Read the treatment emergent effect from National library of medicine. M 32 2 years
60
5/8/2016
 1  Nerve pain depression anxiety Brain zaps, virtigo, disorientation, cognitive empairment Also because it is expensive I fight with insurance to get it covered M 26 4 years
90 1X day
6/5/2016
 1  PTSD Symptoms After 4 1/2 years on Cymbalta(30mg), and still dealing with Depression from PTSD, I had a 24 hr psychosis event and ended up in the emergency room. My doctor then thought it best to bump my dosage to 60 mg. That extra 30mg of Cymbalta , almost was the last nail in my coffin. Within a few months I was always irritable and angry verbally abusive to my family. My anxiety was on full blast and I couldn't turn it off, causing tremors and restless legs. I slept 3 to 4 days a week, and I had extreme depression. I had migraines and lived in a fog and couldn't even comprehend basic responsibilities , like paying my bills or working my cell phone. I showed paranoia symptoms and my blood pressure would raise or drop at any given moment, I was often dizzy or light headed, probably from the raising and falling of my blood pressure. My heart would beat rapidly much of the time, and my sleep patterns way off. Because many of these symptoms resembled extreme PTSD symptoms and my VA doctor so many mil I am experiencing residue side effect, after a few months without Cymbalta, mostly in tremors and restless legs. Also there is alway an amount of anxiety and nervousness that I never had before, and now rarely goes away. M 50 6 years
60 mg 1X day
6/10/2016
Email
 1  Depression Anxiety At first i thought that this was a wonder drug. Then I found that if i was a little as an hour past time to take my next dose i started feeling horrible. The brain zaps would start and lets not even start with the nausea. I ran out of meds about 3 days ago with no way to refill so I said ill just have to tough it out. My god ive never felt so terrible in my life. I haveterrible sweats, headaches, stomach discomfort, dizziness, brain fog, vertigo, fatigue, lethargy, body aches, elevated blood pressure, shakiness, weakness, blurred vision, cant hold a conversation for more than a couple of minutes, anger, and this one is more my fault than anythimg, after 2 years of no smoking, i picked it back up a day or so ago, and am smoking more now than i did before i quit. This crap is a curse more than anything else. Sure, it does what it is supposed to, but at what cost? M 30 4 years
60 mg 1x a
5/27/2015
Email
 1  Anxiety I wake up nearly every morning in a fog. I feel all of my cognitive functions have been muted. I feel off balance or dizzy. I feel like my vision is different. Get drunk from one beer, fear its from the heavy toll this medication is taking on my liver. Poor memory, can't concentrate, simply do not feel like myself anymore. I tried cymbalta because I was in a constant state of panic due to health anxiety. The only good thing I have to say about cymbatla is that it does take care of anxiety, but I would imagine that a simple SSRI would provide the same results without the unwanted side effects. I guess I can't say the way I am feeling is all due to the cymbalta, but there is a definite correlation between how I feel and when I started taking this medication. M 29 6 months
30 MG 1X day
4/6/2015
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