DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2470 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Birth control Bleeding non-stop. No sex life with this shot. F 44 15 days
1X day
11/13/2023
 1  Prevent Pregnancy I’ve had horrible mood swings in just 16 days of my first shot of Depo, this is ridiculous. I’ve had horrible cramping and vaginal dryness. I don’t have intrest in sex anymore and it’s just horrible. I don’t understand why they didn’t tell me these side effects I could possibly experience while using the shot at the doctors office. The Depo shot should be discontinued and considering my age, they shouldn’t offer it to teens. There’s plenty of hormonal things going on with me right now, this doesn’t help. I always have an attitude and I’m basically angry at the world 24/7. As soon as I go to my doctor’s appointment, I’m getting off of this. This is so ridiculous and I should’ve been told beforehand the symptoms. I already struggle with depression and this isn’t helping. Do not take the shot. Get the pill or another contraption. This is medically unsafe and should be recalled. The symptoms are too horrible, especially when you have another medical issue already, this just doesn’t help. F 16 16 days
30 MG
6/1/2019
 1  Birth control Extremely tired. Loss of appetite. My mood is fine. Some days are better than others. F 19 18 days
1X M
8/18/2020
 1  birth control Nausea, non-stop bleeding I got the shot on Nov. 15 and it seemed as if my period was starting to go away, which is what I was hoping for. I just kept spotting and spotting for a couple weeks. Then I just started bleeding more and more. Now it's going back to spotting a tiny bit. Recently I've been nauseous and throwing up and have been having pregnancy-like symptoms. It's disgusting having sex. My boyfriend doesn't not want to have sex, so we do, and it's very messy and bloody. I can't take it much longer. I'm definitely not getting another shot. I'm too young to be destroying my body like this. F 20 18 days
12/3/2008
 5  Birth Control Occasional spotting if I am overdue for needle. I have no period at all and it has been extremely effective as birth control F 42 19 days
3/20/2007
 3  Prolonged menstrual bleeding hot flashes, night sweats, mood swings i havent been on it that long, less than a month. the side effects im experiencing are tolerable, well so far. my body did start to feel weird a week after i got the shot. my doctor said thats why she prescribed a multi-vitamin supplement for me to take also. maybe that can work for some of you experiencing stronger side effects. Good Luck!!!! F 30 20 days
1/23/2009
Email
 1  very heavy prolonged period Terrible experience!! Almost stopped bleeding and clots entirely for a just under 3 weeks weeks. About day 20 bleeding heavy started again with bad clots and worst cramps in my life in my abdomen and back . Felt like childbirth! All over body aches like I had the flu. Dull headache, insomnia, extremely moody and fatigued. Called dr, scheduled d & c, got off Provera and put another birth control and pain med for severe cramps. About 2 1/2 days being off Provera, bleeding almost completely stopped, NO cramps, no headache or body aches, great mood! Calling Dr. tomorrow to see if I still need d & c. Not sure what to think...did almost stop my nightmare period but came back with a vengance!! Would NOT take Provera again! F 43 20 days
10mg 2X day
1/28/2012
 1  lighter periods/birth control depression, anxiety, complete loss of sex drive and lowered sensation, headaches, nausea ive been on the shot since April 19, and within that day i experienced drastic mood swings, depression, and complete loss of sex drive (which was NEVER a problem before), and i am still experiencing those, in addition to lowered sensation during sex. it is affecting my relationship to the point where my husband almost left because of my mood swings and loss of libido. i cannot drink alcohol because it makes the mood swings so much more severe. im due for another shot july 16th and i do not plant on getting another one ever again. stay away from this. it will ruin your life. F 22 24 days
5/13/2007
 2  prevent pregnancy minor abdominal craps, tiredness, extreme pounding headache, shortness of breath, heart palpitations, nauseau I saw my doctor about some dizziness/vertigo I was experiencing. Before she gave me a prescriptions, she did a pregnancy test to make sure it was safe for me to take the medication. I went for a followup and she asked if I was on any kind of birth control. I told her no because I've had problems with other kinds of birth control before. She quickly goes on to tell me how great depo prevara is and that I should be on it, side effects are minimal, its the best out there for me. It was so sudden, I didn't really have time to think to really ask any important questions. Any questions I did ask, my concerns were downplayed and all I heard was how great this would be for me. So I went ahead with the shot. Now I'm having these side effects, the headache is extremely intense. I've only been on it for about a month. Has anyone else been in my shoes, will the side effects eventually calm down? If this continues, I want OFF! HELP! F 30 28 days
2/17/2009
Email
 2   no energy, tiredness, not hungry, more annoyed, excessive spotting. i have only been on depo for a month. i had a lot of pain in my arm and shoulder after i first took it. i went pretty much symptom free for the first 3 weeks. i noticed i was getting tired in the middle of the day and im sleeping more then 12 hours a night, but i still just want more sleep. i have no desire to eat at all. i am on a mood stabilizer for my bi-polar disorder so my mood does not go to extremes, but i am getting really annoyed with my friends, family, and my bf. i dont know if thats because of the shot or my lack of energy. i am constantly cramping up like i would on my worst of periods and i have been spotting for 8 days straight already. the spotting increases after sexual activity and it is really causing me problems in the bedroom. i got this shot to inhibit the chances of getting pregnant and the shot works in the aspect of which im too tired and spotting too much to really want to have sex... thanks depo provera!!! F 18 28 days
4/16/2009
 1  pregnancy prevention Moderate to severe depression, weakness/shakiness, tired all the time, nausea, no appetite whatsoever, decreased sex drive (so what's the point right?) F 19 30 days
7/30/2009
 1  prevent pregnancy Migraines, spotting, emotional, lack of sex drive, uti. Have only been on the shot for a month and i hate it. I have had a migraine for the past nine days and it is still going strong! Going for a CT Scan tomorrow. I have had spotting for the past two weeks. I cry over the littlest things. I went on depo because I couldn't remember to take my pill and got pregnant twice...i will remember it from now on! I didn't realize how many people have had migraines as a result. I've been scared to death wondering why the headache...but now i know! NEVER taking this junk again F 21 30 days
3/3/2009
 1  birth control nausea, headaches, fatigue, hunger, muscle ache, frequent urination, moodiness, depression, weight gain, acne. i have never been more miserable. my doctor only briefly warned me about a little weight gain and spotting, but ive had no period at all. that would be fine if i wasnt so worried about being pregnant now. this has been the most stressful experience of my life, i would rather have had a baby. F 18 30 days
2/3/2009
 1  Contreception Headaches, Nausea, Drowsiness, Fatigue, Anxiety attacks, Extreme Nervousness, On edge, Angry at the drop of a hat, Extremely moody, Night sweats, Hot Flashes. Never in my life have I ever felt like this all at once, and I think I can count on one hand how many times I have gotten a headache that stopped my daily activities, until I took the Depo-Provera shot. At first I though something was really wrong with me until I saw this sight and realized I had all the same symptoms as many of you. F 20 30 days
1 Shot 1X O
9/14/2011
Email
 1  Birth Control Immediately starving after getting the shot, constantly starving after getting the shot, joint pain in shoulder and knees, night sweats, vivid dreams, increased sense of smell, morning sickness, weight gain (almost 4 pounds in one month), bloating, depression, mood swings, fatigue and exhaustion, skin rash on face, hair falling out everyday, bleeding after sex, bleeding heavy for 10 days, passing HUGE clots, dizziness, sore breasts, decreased sex drive, ovary pains, alcohol aversion, smoke aversion, all over body aches. It's like being pregnant, except you are not pregnant, constantly starving, taking SLIM SHOTS to reduce appetite. Cannot have sex because of heavy blood flow, feeling the worst that I have ever felt. Passed clots so large I was worried for 3 days. At least pregnancy has a purpose. I don't think that I can continue this treatment. F 32 30 days
1 shot 1X AN
7/7/2010
 1  Painful periods Breast tenderness,fatigue,fluid retention,sadness,unable to lose weight-but i havnt put any on either while being on depo which people say they have done,aching limbs,light period 24/7 since the day of 1st and last of the injection I wanted to have the depo provera injection because for many years now i have been having extreme pain with my periods and,because i have had M.E,(chronic fatigue syndrome)it made the pmt a million times worse and i was bed bound with no energy and looked as white as a ghost.So i thought this would help me.I DID i must say look at this forum and i read all the horror stories and comments so i knew the side effects and knew what i was letting myself in for.But i thought,i might be the lucky one and everything will be fine-NO.I had my first jab 31 days ago and,even though things were ok to start with during the 1st week,things went down hill from then on.Id been healthy eating and exercising prior to the injection and had lost 9 pounds.Yay.But the week after the jab id put it all back on again which f****d me off so much.Then i started to have no energy to carry on with my exercising,which after 9 years of M.E and finally recovering from it and getting my life back to normal and getting my energy back,the energy was zapped again.So anyway,as the next few weeks went by,my period has been on and hasnt stopped-light spotting constantly.The thing that i really hate about depo is just how its making me feel.Losing all my energy again.Ive had my fair share of that to last me a life time and i want it back.I havnt put on any weight since the injection but i havnt lost any either.I feel massive though and it is just because of the fluid retention i know but it doesnt make me feel any b F 32 31 days
1X O
4/28/2010
 1  birth control Im actually posting for my girlfriend, she had her first shot just over a month ago, things seemed normal, then she got her period which the Dr told her she wouldnt even get anymore, now its been over 2 weeks and it hasnt stopped. So she saw a Dr today about it, he told her to "deal with it" (his exact words). Now after some research I see all this. Wtf hasnt this been banned, its ruining my GF's life, she's depressed, moody. This drug should be banned. Dont let anyone you know even consider taking it! very effective as birth control though, because you wont get to have sex again. F 27 35 days
8/28/2006
 1  To control heavy bleeding I received my first injection 2/14/11. I started my period on 3/4/2011. It is now 3/21/11 and I am still bleeding. Five days ago I started passing huge clots -so painful it feels like labor pains instead of mentrual cramps. My back aches and I ache from hip to hip across my pelvic reqion. It feels like I've got a stick up my butt. The pain I am feeling is excrutiating- level 10. Midol, Acetamephine and Ibuprofin are just barely masking my pain. I'm moody, and have a headache. Visited the Doctor today, though I considered an Emergency Room Visit because of the pain level. The Doctor tells me I have to give Depo-Provera a period of several injections to see if it will control/stop my heavy bleeding. I don't think I can stick it out! This is torture! I think all Doctors should provide a strong warning to patients about the possible side effects and most common patient complaints. This medication was presented to me as a very probable cure for my menorraghia. If anything, my condition is now worse and not improved. I would have thought twice about taking the injection if I would have known how many women are helped or harmed by this injection. The ratings, so far, according to this website indication more harm than cure. F 48 38 days
400mg 1X O
3/21/2011
 1  yes continious bleeding. My Doctor never metioned this side effect. F 42 40 days
1X day
11/14/2010
 1  dr recommended numbness in face, arms. legs, shakiness, tight chest, rapid heartbeat, burning sensation im my stomach it is horrible and should be taken off the market asap. anytime there is no reversing a drug that does this much harm it is dangerous! F 26 40 days
7/16/2007

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