DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 3  birth contro; No periods, weigh gain ( but I don't eat well either) While I was taking it I had no problems. I was 14. Weight gain was about it, but I don't eat very healthy or exercise. When I got off of it (age 22) I spotted continully for 3 months. Then went on the pill. now almost 3 years later I am having major problems. While on the pill (the same one after 3 years) I am bleeding with intercourse, massive bloating, more weight gain. I have every test my MD can think of and can't tell me why I keep bleeding. Maybe because of Depo but maybe not. anyone have this please tell me. Thanks F 24 8 years
 1/12/2008
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 2  birth control acne I am 25 and have never had acne before but now have bad acne which is scarring my face. Went to my regular physician who told me that this was probably due to depo provera. In fact, she said that women who have been on depo provera for a while tend to develop acne. F 25 8 years
 4/15/2007
 2  Birth Control Major Weight Gain I started taking the shot when I was 16. It was great for a while. No periods. I had no side effects whatsoever. It was the best thing since sliced bread. Then I got into my early 20's. Around the age of 22 I started gaining weight like crazy. I would diet, exercise. Nothing was making the weight come off. And I am a very small person. Anyway, I gained 20lbs. I was up to 145lbs. The heaviest I had EVER been. Then one day I was researching and I heard about all of the horrible weight gain stories. So....I stopped getting the shots and lo and behold, I lost every bit of that 20lbs without even trying really. My normal weight is 125lbs and I am able to stay there without much difficulty. If it weren't for the weight gain, this would be a great method because I didn't experience any of the other typical birth control side effects like I have with other things I've tried. F 32 8 years
1X AN		 6/8/2011
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 2  Birth Control acne, nausea, weight gain, mood swings, anger, low to none sex drive, brown spot on cheeks Coming off the depo I feel is so hard and cant wait till the symptoms END!!! I am angry all the time, feeling depressed for no reason(just moved to a wonderful area, husband stopped drinking and my son is doing awesome in school I have no reason to be depressed) I feel like Im pregnant all the time but tests show negative, after getting my period for 8 days I am now 23 days late and still waiting, I never thought I would want my period to come so bad as I do now, my doctor said I should be back to normal in about 3 months and i pray he is right as I want to have another baby ASAP...Note to self and anyone reading: Will Never Take The Depo Again!!!!!!!! F 29 8 years
1X day		 10/5/2010
 1  Yes Blurred vision (goes clear then blurry again), nausea(terrible), sweating (underarms/palms), dizzy, trouble breathing, feeling nervous. I am not sure what to think. I had happily been on depo provera for many years and had done well. In january 2005 the doctor had switched me from name brand depo-provera to the generic brand. I started getting the symptoms I listed right after the shot in January. I asked my doctor if the way I was feeling was do to the change from name brand to generic he said no. Because I was on it for so many years there is no way that what I am experiencing has come on from the shot. I have been to the doctors and tested and I am as healthy according to blood/urine tests. I don't understand why I am having these symptoms. I got a few more opinions from a pharmacist and two nurses and have been told it is possible that what I am going through is from the shot. For numerous reasons e.g. body changes... Well it is now months later July 08, 2005 in fact and I am due for the shot the end of this month. I am going to stop taking it and see if in a few months that these symptoms dissapear. Prior to all of this I had been healthy happy and in college and working overall I was doing well. F 29 8 years
 7/8/2005
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 1  to prevent pregnancy depression, major increase of breast size, breast soreness, heavy irregular bleeding, night sweats, hot flashes, major mood swings, 30lbs.weight gain, growth of facial hair, acne, blurry vision, leg cramps, joint soreness, loss of sex drive, no menstal cycle, yeast infections, bad headaches, i have not taken dep0-provera for 2 years now and I am still experiencing severe side effects. ( I have not taken any birthcontrol in 2 years) Anytime I do any extreme physical activity that causes my body to burn fat, it releases the drug back into my system. It then causes my menstal cycle to go away for months. I do not recomend the use of this drug to anyone. I was 14 yrs old when a school nurse recomended it to me, thats how i got started. I am now 26yrs old. If anyone is experiencing the same grief as I am, please feel free to contact me by my e-mail, as I would really like to talk about this with others that are going through what I am. I also would like to add that anytime I have brought these issues up with nurses at my clinic, they informed me that I was too young to be experiencing any side effects and brushed off my pleas for help. They tried to just give me birth control pills and said it would get rid of the problem. I tried it for 3 months and it made effects way worse. F 26 8 years
 1/24/2008
 1  birth Control NO sexual drive-headaches-back/neck problems-rage-depression-weight gain-night sweats-heavy sweating during activities-nausea-cramping you name it.... However - I contributed the majority of my symptoms to depo for years, so did my doctors, even when new symptoms came up such as sleeplessness but constant major exhaustion, heart palpatations and major hypertension. Over the years I would gain more symptoms and complain to my doctor but it was ALWAYS blamed on the depo. See, after giving patients like my self, a 99.9% effectiveness, the doc has a hard time convincing them to try a different route. I would have Panic attacks BEFORE I started taking it because I was literally afraid of getting pregnant again....I have been on the depo for more than seven years and was just diagnosed with GRAVES DISEASE - multiple tests were done to confirm. My symptoms worsened dramatically to include the inability to concentrate, deal with situations that arose with my children/husband, I began to sweat profusly, night and day, I experience heart palps, dizziness, nausea, severe migraines and I was so hyper I would scream at anything that had a mou F 34 8 years
 5/20/2008
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 1  Unbearable periods I can completely relate to the stories of those taking the Depo shot for more than 1 year, 40lbs in weight gain, excessive peeing, sever depression and anxiety, complete lack of sex drive, the works. I mean just about everything the other readers have noted. What I want to share with everyone is the fact that over the 8 years I was on Depo, I moved several times and of course changed OBGYN’s. Never once did any of the doctors mention that you SHOULD NOT be on Depo for more than 2 years. I finally got tired of the hour wait for the shot at the OBGYN and turned to my regular doctor, whom upon hearing how long I had been on it denied me from getting the shot anymore. After about 5 months of being off the shot, I dropped a little over 20 lbs out of nowhere. It's been 19 months since my last shot and I still have not had a period. Personally I am fine with not having a period as I don’t plan to have children, but it would be nice to know if/ when I am going to get one. You SHOULD NOT be on Depo for more than 2 years. F 35 8 years
 3/23/2009
 1  to prevent pregnancy I have had horrible weight gain, zits, hair loss, bone loss, mood swings, depression and anxioty. My mom died of overian cancer, 3 doctors told me to go on depo to prevent pregnancy after my 2nd miscarriage. When I started to gain weight it wasn't an issue with my doctor, I went to a different doctor and still wasn't an issue I was told to stay on it since it would lower my risk of overian cancer. When I broke my wrist after loosing my mind one night I was told I had very bad bone loss that they normally don't see that till your 60's and at that time I was 27, I went to a different doctor and was told there was no bone loss. I have suffered from major anxioty attacks that seemed to go away if I ate, which I suffered from the last 6-7 years, my doctor told me low blood sugar till I had a glucose test that was normal, I figured anxioty and the pills he gave helped so I guess I was right. I have over the last 12 months gained 30 pounds, still no concern to my doctor, now I weight almost 300 and I am only 5'4, I tried to loose weight with diet and exersise and I again gained. I can only figure it is the depo shot, I asked my doctor and he said everybody's bodies are different but it would be a step in the right direction to get off the shot. I have actually gained roughly 160 pounds in the 8 years on the shot and not yet sure what else is wrong with me. F 30 8 years
 2/7/2005
 1  contraceptive Horrible mood swings, no sex drive, and headaches. After almost 10 years on this medication i began to hear of many serious problems related to it. I worked for an OB/GYN at the time i began this medication. Like most of you i was told by the DR and the pharmacy reps that this drug was safe for long term use. Well, now we know thats not true!!!!! I recently had a bone scan done to only now find out that i have Osteopenia (the begining stages of Osteoporosis). I am only 28 years old. This is what i have to look foward to now as i age. I just wonder did they know these problems before and just failed to say like many other drugs they put on the market or were they just to cheap to do the research! Either way its careless and just pure GREED. F 28 8 years
 9/26/2007
 1  birth control anxiety, depression, weight gain, hair loss, muscle aches, stomach problems all of which kept getting worse until i realized it was the depo causing them. This is the worst bc in the world I have never had so many health problems in all my life. Coming off of depo was a nightmare but I am so glad i have. Last shot was exactly 6 months ago and am finally starting to feel human again. I literally thought I would die. Started having panic attacks, nausea, vomiting lost 30 lbs in a matter of weeks which i feel kept releasing this poison into my system since depo is stored in the fat. Countless dr visits and no one could find anything wrong. Only 1 dr would believe me that it was the depo. AF has still not returned and who knows if it ever will. Gyn wants to give hormones I said NO WAY!!! never again. Good Luck to all of you going through this just believe there is a light at the end of the tunnel. F 41 8 years
 6/12/2007
 5  B/C & No kids Before DP, I was already irregular. After depo, no period like many others. Had migranes which I thought were due to stress. All over body aches which I thought were from lack of exercise&stress. Lower back pains thought to be from epideral. Increased sex drive, increased appetite/sugar cravings. Before depo, 120llbs. Now, 9 years later, 160llbs; thought this was due to having 2 kids and not exercising. People say your body changes every 5 years. Now, I am 30. I have loved Depo up until this year. Now, around the "time of the month", I have been experiencing severe depression and acne I just can not get rid of. I have been on calcium, women's 1 a day, and green tea pills (curbs appetite and sugar cravings, increased energy with natural caffine), blueberry (antioxidant which helps with depression)protein shakes, high-protein diet, exercise, and I have lost 7 lbs in 1 month. I thought losing weight on Depo was impossible! Herbalist recommended SAM-E for depression. I am working on the acne cure still. Depo is not for everyone and after visiting this website, thinking about a bone density test. F 30 9 years
 7/2/2007
 5  breast pain and tenderness no period, lower sex drive, possible loss of bone density I started depo for birth control while breastfeeding and happily discovered that it relieved me of the nearly constant breast pain that I had had for 3 weeks of every month since my early 20's. They used to hurt whether or not I was on birth control. I seem to be the only person on this site with this situation. I have been very happy with depo, but I am going to stop soon to protect my bones. I do worry that my breasts will hurt again like before. I don't know if my periods will return as I now have hot flashes and have started menopause. Depo seems not to have affected my weight nearly as much as my exercise and diet do--my weight has varied by 12 lbs. up or down in 9 years. F 42 9 years
 6/27/2007
 5  No Period! Birth Control Some weight gain in the beginning.. I guess only the people with bad experiences are looking this up because I am by far an exception to what appears to be horrible experiences. I was on the pill for years, went off to have a baby.. after baby, couldnt remember to take my pill (go figure) so I switched to the Depo shot.. I am also a smoker so this was a better choice for me. Keep in mind that I was 31 when I started this shot so I am not as concerned with my "bone density" because of my age. I am still on the shot, and will continue to stay on it until I have a hysterectomy. I am at high risk of endomitriosis but have always been on some form of birth control so keep it from developing. I do not have health insurance so I get the generic form which is 1/2 the cost of the Depo. I also give myself the shot. F 40 9 years
 12/13/2008
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 5  Heavy periods w/ bad cramps Minor headaches, weight gain, slight loss in sex drive. I got put on Depo Provera when I was 15 years old. I had extremely bad periods and they put me through rounds of different birth control and other medications and gave me depo as a last resort. I absolutely love it and feel it has been a big life saver. It does work differently for everybody but I feel a lot of people blame other symptoms on depo that are not even related!! I did experience some minor headaches and then realized a lot of it had to do with my eye sight going bad, once I was off depo the headaches continued until I had an eye exam....I did experience a little weight gain which I learned to control by eating better and exercising regularly. I had a slight loss in sex drive but I just took a medication that helped fix that because I pretty much require Depo to function... It is recommended to take breaks every 2 years from it and during that year break I am so miserable my periods pretty much stop my life and I am bed ridden. Nothing else works for me, I can pop heavy pain F 23 9 years
 6/4/2008
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 5  Disease control/ Birth control No period since start of shot in 1999, severe cramps every 6 months along with migraines. Despite the side effects I love the shot and would recommend it for anyone who does not enjoy pills or medical procedures. Personally I beleive Cramps, mood swings, migraines, etc. are more easily controlable than Lupus symptoms. My Ob/Gyns have all tried to discourage me from the shot recently b/c of the balck box deal but I am taking DHEA to conteract the bone density issue. F 25 9 years
 6/15/2008
 5  Birth Control Weight gain (40lbs), depression, no sex drive, no bleeding, lethargy, severe back pain. I was on depo for 9 years and loved not having a period. But I am tired of gaining about 5lbs every injection and NO IT'S NOT FROM POOR NUTRITION OR EXCERSIZE. My last injection was in February 2006 and will not ever get it again. I am currently on day 17 of heavy bleeding, but I feel more alive. I just can't wait until it gets out of my system. I have more ambition now. My libido has increase significantly. F 24 9 years
 8/13/2006
 5  turned 35 and smoked so dr recommended some weight gain, no periods i love the shot and will continue it F 44 9 years
4X O		 4/4/2011
 5  prevent pregnancy Loss of period, which used to be horrible so I don't miss it. A little vaginal dryness but nothing a little lube doesn't solve. Sexual desire is still the same. Always been moody so I haven't noticed a difference there. I love it but it apparently effects everyone differently. F 37 9 years
 2/17/2012
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 5  No pregnancy or periods Hair loss and muscle pain weight goes up n down F 30 9 years
 4/25/2017

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