DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Heavy cycles and prevent pregnancy Never had a problem with any of the following until I got on that terrible never want again shot. Vision problems, heart palpitations(PVCs that have sent me to the e.r so many times I lost count), migraine headaches, dizziness, anxiety, nervousness, panic attacks, shakiness, depressed crying all the time and couldn't figure out why, shortness of breath, stomach issues, bloating, night sweats just not feeling like myself. All tests kept coming back normal no one could find a issue which was frustrating because I knew and felt something was wrong except my white blood cells, platelets, and d-dimer kept coming back elevated which led me to being at risk for deep vein thrombosis. Have been so scared for over a year and finally a nurse practitioner at a gastroenterologist appointment I had said "it may be the depo shot causing these issues. Started investigating and voila' found other women having difficulties with this also but bad part is it took me so long to tie all I've been going through was the shot. My primary doctor kept thinking it was all in my head and had me seeing a psychiatrist and being on anxiety meds. Can't wait till this is out of my system. Wouldn't wish this evil on anyone. F 38 2 years
 11/14/2019
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 1  Prevent kid Was 21 at the time where I stopped taking it. The depo stayed in my system for 5 good dam years!!!!!!!!!!!!! After the injection Now 26. Good luck F 21 2 years
1X day		 10/27/2020
 1  To prevent pregnancy Extreme weight gain, and extreme moodiness. I stopped getting my period which was nice. The doctors tell you what to expect while taking the shot. But nothing about after you stop. I went through withdraws. I stopped taking it, my last shot was December 2021. I still have not gotten my period and I thought I was dying while going through withdraws. The after effects are not worth the pregnancy prevention. F 21 2 years
30 8X O		 7/25/2022
 1  Birth Control and no periods Weight gain, mood swings/depression, and dead sex drive/vaginal dryness. I hate myself so much for taking this! It has messed me up so much. My legs are covered in stretch marks from this horrible stuff. I'm going to switch to another birth control as soon as possible. Stay away from Depo Provera!!!! F 19 2 years
 4/29/2009
 1  Birth Control Weight gain, loss of sex drive, vaginal dryness. Before I took this, I was on the pill, and had a hard time remembering to take it. So I started on the shot. I was on it for about two years, from age 17-19. Since starting my sex drive has completely disappeared. It is harder for me to get aroused, mentally but especially physically. Before the shot I had a very, very high libido! This was the biggest change for me, the second biggest being the weight gain, 10+ pounds in two years, I am 5'7 and very slim and used to have an extremely high metabolism. I stopped taking the shot over a year ago. In the last month or so I have dropped over 8 pounds out of nowhere. I have still not had a period. I'm not trying to get pregnant, but I would like to regulate my body and be normal again, as blood tests revealed that my progesterone levels were menopausal (I'm 20 and going through menopause!) so my doctor put me on Prometrium and I'm on my third month of taking it, still no period. NEVER take this shot as it will mess with your hormones and make it hard to regulate your body!! F 20 2 years
 4/29/2009
 1  didnt want to take the pill No sex drive,breast milk and periods last months some times. Don't listen to your doctors.They tell you it will straighten put in a couple months.BS.It just got worse. Heavy periods,breast milk showed up and now theres lumps in my breasts.I'm tired all the time no sex drive have no desire to do anything. I just feel like a bag of crap.The pill is the way to go. F 16 2 years
 6/8/2009
 1  Bith Control I actually lost weight..too much if you ask me. I lost 60 lbs. Most would say that was great however I was only 158 lbs when I started taking the shot. I was 18 years old. Sore breasts is an understatement. Now almost 10 years later, I still have no children. Talk about your sterility. At first it seemed like a great invention to not have the monthly curse. When you are 18, "sowing wild oats" it seems like a God send..now after going thru all that I have to get pregnant, Depo seems to have been a HUGE mistake. I took the shot for about 2 years and didnt have a period for an additonal 2 1/2 years after I stopped taking it. F 28 2 years
 11/9/2009
 1  birth control I have had terrible mood swings also very irregular periods, in one month i've been bleeding for 24 days so far and it shows no sign of stopping. i sometimes get bad cramps, headaches and sickness. to be honest if my doctor had told me more about this contraception i would never of even considered it... you may not experience prolems till you try to come off it, i dont think this injection should be given out unless the doctor explains what can happen during and after the shot. always find out as much as you can about any contraception before you decide to go with it, i regret not doing this myself. im now on the pill to attempt to reset my system(replaces the hormones from the depo) im not sure it works but apparently it does so im giving it a go, it cant get any worse than what im experiencing now. i hope this little bit of info helps any one experiencing the same problems as myself :) dont take it!!!! F 21 2 years
 10/17/2009
 1  Easier than taking tablets Irregular bleeding and spotting, loss of libido, bad mood swings, depression, didnt want to go out Please dont anyone ever take this horrible drug. It has ruined my relationship due to the terrible mood swings and depression, i wasnt warned of any of this and didnt understand what was going on with my mind and body, saw doc 3 months ago, came off it and had copper non-hormonal coil fitted but can take up to 6 months for effects to leave your body so had to go back on anti-depressants to get me over the worst of the depression F 35 2 years
 10/29/2009
 1  birth control weight gain, mood swings, vaginal dryness, absolutely no sex drive, headaches, dizzines, breast tenderness I was on the shot for 2 years, took my last one two months ago. I still am experiencing most of the side effects and have not had a period yet. I would not recommend this shot. F 29 2 years
 10/21/2009
 1  ovarian cysts depression, anxiety, 20 pound weight gain in a matter of two years (by the way i am a health freak and do excercise three times a week), severe acne, kidney stones, kidney problems, dehydration problems,and horrible migraines. the whole reason i had to take depo was because of ovarian cysts, but yet i am still gettin cysts every month almost. this is ridiculous i am going through bone and kidney problems at 16 years old, i would definitely recommend to anyone, to get off of this monster! F 16 2 years
 6/22/2009
 1  birth control weight gain, period for 3 months straight, moodiness, stomach issues, consitpation and diarrhea, some hair loss Ever since starting depo, I haven't been able to lose weight and I just pack on the pounds even though I'm active. I was on the shot for 2 years and just went off it almost 2 months ago. Since going off, my breasts have been tender and sore. I still am packing on the pounds. I still haven't seen my period yet and after reading about other's experiences, I don't expect my cycle to return to normal anytime soon. My husband and I want to try to have a baby but I'm terrified it'll take a year or more. I've been having bad headaches since going off the shot. While on the shot I wouldn't have a bowel movement for a week or more and then when I did have one, it would be diarrhea. It was awful. It was like this every week for 2 years. I just didn't realize it was the depo causing it until I got off of it. I wish I would have had the sense not to use this form of birth control. F 30 2 years
 9/2/2009
 1  birth control SEVERE WEIGHT GAIN, knee and anklejoint pain I was 110 lbs when i originally started taking the shot a year later I am 142 lbs. I have always been slender with a very tiny frame and have never had weight problems, Ever. I wouldnt recomended the shot for anyone. Maybe someone suffering Bulimia or anorexia F 20 2 years
 8/4/2009
 1   sign this petition please if you have been affected by side effects http://petitions.number10.gov.uk/Depo-Provera F 36 2 years
 1/13/2010
 1  horrible periods HORRIBLE!! I had very severe periods since getting my first period at age 11. From Heavy bleeding to cramping so intense feeling as though being "gutted with an ice pick" as well as painful cramping in my thighs. I had tried every form of birth control known to man growing up. After having my child and not wanting to have any more at that time I first tried the Depo shot. It really sounded like a dream come true for someone like me who has gone most their life in such pelvic pain due to my menstrual periods. I quickly learned just how wrong of a decision it was I had made for my self. I no longer felt like myself. My moods were unpredictable and yet so destructive. I always felt tired, never wanting to do the normal things I have always done. I had no motivation for much of anything at this point. Tossing the idea back and fourth wondering if it was due to depression which I had experienced before but yet this still felt very different than any depressing moods I had befo F 29 2 years
30 mg 1X M		 12/13/2013
 1  Birth Control While I was on the shot I didn't have any BAD side effects. I never had a period sense my first shot. The only thing I noticed was when I got the shot every few months I would be dizzy and just didn't feel well for a couple days after wards. I have sense stopped taking the Depo, my last shot was 15 months ago and I am still having problems. VERY irregular periods, and I have suddenly started suffering from depression. Almost like my body is going through a "withdrawal" from being on this drug. My hormones are all screwed up. Before taking depo I was a HAPPY, HEALTHY person with NO history of depression or anxiety. STAY AWAY FROM THIS NASTY STUFF! * No negative side effects DURING the time I was on Depo *DEPRESSION once I stopped taking Depo * IRREGULAR periods for over 1 year after stopping Depo F 25 2 years
1X O		 2/3/2014
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 1  Contraception Depression, mood swings, loss of libido, hard to get pregnant. Hate this drug. I will not encourage anyone to take it. I had severe side effects. F 26 2 years
1X O		 9/6/2013
 1  Endometriosis This drug should not be given to anyone! Doctor never told me about the side effects and didnt give me the option to research it first. He only told me that it doesn't actually make you gain weight but you may think you're hungry more often. Big load of BS!! I went through 2 surgeries because of severe endometriosis that thanks to other doctors who refused to listen I went for 10 years before I was diagnosed. Anyway I was instructed I needed to be on BC that would stop my monthly cycle. I have become depressed, very moody (the littlest things upset me), loss of sex drive, lower back ache, constantly worried, and has possibly ruined my marriage. Now I have to deal with coming off of it. I am done with BC and I am scheduled for a hysterectomy. Hopefully this crap doesn't take too long to get out of my system so I can feel like my old self again, the woman my husband fell in love with, not this crazy person. F 39 2 years
1X O		 8/21/2014
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 1  Birth control method So started out normal, no side effects such as bleeding/spotting, cramps, weight gain (except I gained 15lbs but I was also a freshman in college so idk if it was the depo or freshman 15) anyway, no moods everything was fine. My skin was even better than ever, or just normal..no issues. I was on it for 2 years, 18-19 years old. I am a highly sexual person & noticed my drive was really really low, I wasn't producing vaginal lub & I had no idea why. So I started thinking about what did I eat, wash with, drink, yadda yadda?? I knew it had to be something I put in my body causing trouble. Googled "libido & low sex drive", BOOM. It's the depo, immediately decided to stay off of it because it wasn't worth the damage. Why use it to prevent pregnancy from a good nut if I couldn't even enjoy the sex?? Pointless. So after about 6-8 months after not getting my 3 month dose is when I noticed change. I begin to have sore breasts (which I have never had sore breast, even when I was growing boobs) I never experienced the sore nips & tits thing. So I figured ok my period will come back soon... & it did, with no cramps (shocker, I'm a crampy girl), regular flow, every month, same schedule. Now the libido?? Let me tell you, I don't know if it was the age difference from now to then but it has came back a whole new system, I have no problem getting hot & heavy.. We can skip the foreplay. It is stronger than ever & getting off Depo when I did was the best d F 22 2 years
 1/7/2016
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 1  Birth control Extreme weight gain, hair loss, depression, bone-cracking, delayed fertility, withdrawal symptoms when stopping I would not recommend Depo-provera to anyone. Its a very effective form of birth control but the side effects are not worth it. Please ladies, just do not take Depo. It ruins many woman's lives. F 20 2 years
N/A		 11/3/2015

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