DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Endometriosis/Birth Control MAJOR weight gain, went from 103 to 150 over the past five years, adult acne on face and shoulders, NO sex drive and vaginal dryness, severe pain in injection site. This was basically the only option I had as far as preventing periods ( I have horrible endometriosis). When I first began taking I weighed 103 lbs, now I weigh 150. I lost my sex drive, spotted, and have had facial and shoulder acne for about the past 2 years because they upped my dosage. Was supposed to get another shot today and I finally told them I can't take it anymore. Thank God for Lybrel, the new bc that prevents periods. We now have more options! F 23 6 years
 9/21/2007
 1  birth control weight gain (30 lbs), constant hunger, depression and anxiety, paranoia, mood swings and irritability, complete loss of sex drive, vaginal dryness and painful intercourse, dizziness, cramping and gastrointestinal discomfort, stomach bloating DO NOT TAKE THIS DRUG! It is poison to your body. From March-November 2008, I gained 30 pounds. I have not changed anything in my lifestyle other then that I am hungry ALL THE TIME while I am on Depo. If I don't eat I get light headed and terrible headaches. I also had a complete loss of sex drive and mood swings and anxiety that threatened my marriage. These were completely new and I had never had this problem before. Every time I tried to talk to my doctor or the nurses, they acted like I was crazy and said my symptoms couldn't possibly be the Depo. Now I find out that my doctor didn't bother to counsel me on the fact that I should have been taking extra calcium this whole time and I have to get a bone density scan to be sure I don't have osteoporosis and I'm 31 years old! If you do research on this drug you will see that it never should have been approved by the FDA. I trusted my doctor and thought she wouldn't give me something that wasn't safe. I was wrong. Don't let yourself be t F 31 6 years
 11/19/2008
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 1  endometriosis, cysts, heavy period migraines, liver and kidney problems, IBS, modd swings, loss of sex-drive, no lubrication etc. Depo is a terrible drug. I have been on it for 6 years. I just recently came off in the last 2 weeks. I have had no period which is great, but I never knew all my other medical issues were because of depo. I have liver, kidney and constant migraines. I have level 1 displasia, which is a cervical cancer cursor. Severe, severe migraines, moddy, loss of sex drive, IBS, constant nausea. All of which I have had for years and my doctor has never said anything. Until the last couple of weeks that I have been researching this, I never knew if haults fertility and could even make you pre-menapausal. Please, please do not take this drug. Yes having no periods is great, but it doesnt outweight everything else. F 25 6 years
 12/13/2007
 1  No peroid/no baby's INSANE WEIGHT GAIN I JUST TURNED 33 YEARS OLD AND WOULD NEVER EVER RECOMMENT THIS DRUG. I HAVE TAKEN THIS DRUG 3 OR 4 TIMES. THE LAST TIME I TOOK IT WHICH I STARTED IN JULY OF 07 I WEIGHED 110 LBS. I STOPPED TAKING DEPO IN MAY OF 08 I NOW WEIGH 150 LBS. I NEVER HAD A PROBLEM WITH MY WEIGHT BEFORE. I ALSO TRIED WORKING OUT EVERYDAY FOR THREE MONTHS AND DIDNT LOSE A POUND. I NEVER HAD THIS PROBLEM BEFORE WHEN I GOT THE SHOT. LET ME ALSO SAY THAT GETTING BACK TO "NORMAL" IS NOT AN EASY THING. I'VE NOT HAD A SHOT SINCE MAY OF 08 AND IVE HAD TWO PERIODS SINCE THEN. CRAZY!! F 33 6 years
 1/4/2009
 1  Birth Control Anxiety, depression, oily skin, lack of sex drive, irritability, insomnia, emotional I took Depo from the time I was 22-28 without any side effects and was a HUGE FAN! Then around the time I turned 28 and my internal hormones changed the drugs side effects came on like a freight train. I stopped the drug and within 12 weeks was a totally different person. Sleeping, enjoying relationships, no more paranoia! F 34 6 years
 12/10/2008
 1  Birth Control Aches and pains in my joints. No periods. Fatigue. Long term complications if taken for more than 2 years. Irregular periods since I have stopped my injections. F 33 6 years
 3/24/2009
 1  Birth Control Extreme fatigue, loss of sex drive, irritablity, mood swings. I have been on this for at least six years and every year I went to the doctor complaining that I was ALWAYS tired. I got checked for everything you can think of and yet nothing. I was clueless to the fact that the shot could be doing this but after reading all these other comments I realized im not crazy. I only wish that my doctor suggested this...I went to three different doctors and non of them said it was due to the shot. How clueless are doctors? My shot is up in May and I really feel like getting off of this will change my life completely. I really hate being tired and irritable. People eating chips drives me crazy!! I would recommend not taking the shot, I feel like it ruined 5 years of my life. I never want to do anything, I always want to take a nap and I don’t care to have sex. Low sex drive can ruin relationships. F 22 6 years
 4/25/2008
 1  endo Weight Gain, Abdominal pain, acne, thinning hair, mood swings, swelling I started taking this medication 6 years ago for endo. I worked extremely well in the beginning. The pains subsided and my period completely stopped. After about three years the weight gain came and I have a hard time keeping a steady weight. The pains from endo persisted after some time and also grew in time. I have struggled with acne forever and the shot never helped. Looking for a new help with the endo I came across a Dr. Albee and read about his clinic and found out stuff that my doctor never mentioned. We talked about how the shot decreases the bone density and there is a risk that you will not ovulate again, that chance is rare but it is a possibility. I am now off the shot for about a week and nothing has happened. I don't know what to expect. Took a pregnacy test, it's a negative so here we go with not knowing what to expect. F 26 6 years
 6/10/2007
 1  Birth Control I took DP for 6 years and THOUGHT it was a dream come true. When I decided to stop taking it, my period did not return as expected. Then monthly I began to experience VERY SEVERE abdominal pains periodically, for about a week each time. severe enough to go to the hospital 3 months in a row, with no diagnosis. Finally on my 4th emergency room visit and after a laparoscopy, a determined OB-GYN finally diagnosed my problem as Retrograde Menstruation. I was having a period and bleeding into my abdomen every month. He attempted to open my cervix but it closed within hours. The final treatment was a complete hysterectomy. The reason for my condition was that I took Depo Provera for more than 3 years. Don't do it ladies. Find a better way. It was the most painful experience of my life, and I have given birth and had eye surgery before. Those don't even compare to the pain of the side effects of this drug. It is a very dangerous drug. F 40 6 years
1X O		 12/1/2010
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 3  Birth control Fatige, dizziness, weight gain, mild depression, insomnia, peripheral pitting edema, loss of sex drive, migraine-like headaches, anemia (never diagnosed as to cause, so could be related to drug), stress fractures (running related, but calcium depletion likely played a role), irritability, foggy thought, joint pain I didn't realize how awful I felt on depo until I missed my last shot. Prior to that, I honestly felt like a positive poster child for the drug. I only had a few instances of breakthrough bleeding over 6 years, and just thought the side effects were "other things". I just happened to not make it in for my last shot. It wasn't a big deal because sadly, my sex drive was so low there was no reason to be taking depo. Within a few weeks of missing that shot, it's like the fog has lifted. Honestly, the only way to describe it is 180 degree change. I have more energy, not hungry all the time, my sleeping is better and I don't feel like I'm dragging myself through the day. I've lost a bit of weight (weight gain over 6 years was only ~10-15 lbs, but that's a lot for me, I feel more energetic, my head feels clear, I'm back to my normal "sunny" self. Strange as it is to say, I was so happy to see my period, and my sex drive almost feels like it's in overdrive after four years F 33 6.5 years
 1/25/2009
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 3  Migraines 1st 2 years: fewer migraines, no period, weight loss, increased sex drive around shot time and shortly after decreased in between shots, vaginal dryness, massive mod swings, possibly some paranoia, for the most part the good outweighed the bad After 2years and counting - migraines are the same as they were before, massive weight gain, can't lose it, diabetes (possibly because of depo or as a result of weight gain), tired all the itme, no period, MASSIVE vaginal dryness - needed a cream, yes ladies it can shrivel up from non use....developed HPV - didn't turn to cervical cancer, constant hunger, dizziness, weaknees, no energy, lack of concentration, joint pain, developing allergic reactions... gonna be honest, there's more the list is huge. I loved Depo the first two years but as I hit that two year mark I started to get wingy. It's been 6 now...The side effects that suck no longer outweigh the good ones. I am going to get off of it. Just gotta find another way to keep the period away - mom likes her IUD. F 26 6.5 years
 11/17/2008
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 3  Birth Control I did not receive a period for the duration I was on Depo. I started Depo in May 2001 and my very last injection "expired" on October 11, 2008. I did not receive a period this entire time, which I really enjoyed. I discontinued this med because I felt like I was bipolar on it. My mood swings were TERRIBLE. Now that I've been off if it for 8 months, my period still has not returned. I feel better (mood wise) but I still feel terribly abnormal because it's taking so long to get my period back. I'm now starting Aygestin to induce a period. Keeping my fingers crossed that depo didn't screw me up for good. F 29 6.5 years
 6/1/2009
 1  yes upon reading everyone's comments in here I have to say I experienced just about everything everyone has put on here, I just did not know at the time what was going on the only thing my physician was concerned about was my bones and I don't think he ever put all my symptoms together with the depo provera shot. I have to say that all I remember is that I went through all the horrible symptoms everyone is putting on and my own physician couldnt tell me why I was feeling the way I was. I just thought it was over stress and now the more I read about this the more I put my symptoms to this prescription. It made me do alot of stuff personally that I couldnt understand why I was feeling the way I was. It's sad that they don't come out and actually state what some women experience severly because all I remember getting is some of the symptoms but I remember it was all general. F 24 6.5 years
? 1X AN		 8/13/2010
 5  Couldnt remember to take the pill PMS like symptoms and some spotting right before it is time for my next shot. I dont have a period other than the occational spotting every couple of months. Depo was my first birth control and it has been great. I have never been one to remember to take a pill every day so once every 3 months is perfect for me. I cannot say any weight gain or other sypmtoms are caused by the depo.. they could be from me being a piggy! I stopped taking the depo and had my son and then started again right after I was done breast feeding. I plan to have another child again in the next few years and continue the shot. I think it's great and wonderful! F 25 7 years
1X AN		 4/6/2010
 5  Migraines No period (a good thing!). No weight gain. PMS symptoms (sore breasts, slightly crampy, etc) when I'm due for a shot. Goes away within 24 hrs of receiving shot. I take one shot every 3 months. I started depo because I get migraines every month when I got my period. Migraines lasted 3 to 4 days and put me flat on my back. Depo takes away my period. No period, no migraine! I LOVE it! Nice not to have to plan around my monthly migraine! Can't wait for menopause! F 46 7 years
1X O		 8/27/2010
 5  to prevent pregnancy loss in sex drive, vaginal dryness, possible weight gain and acne I loved "the shot"! It is worry free and not having a period makes life a lot easier. I was on it for 5 years, went off to give my body a break, to get back to a normal cycle. I got my period two months later. The period I did have was unbearable. Cramps like I never had before I went on depo. I didn't get another period, because I found out I was pregnant three months after going off. I went back on after I gave birth. I have been on it for two years now and was due for another shot in November, which I did not get. Now my breast are tender and swollen. I took a pregnancy test and it was negative. After looking on the web, I found it might be a side effect of going off "the shot". Depo is great, but remember it is not "normal" not to get a period. F 24 7 years
 12/17/2006
 5  As BC and for period relief Bone pain, muscle pain, acne, weight gain, fatigue, MS type symptoms. I think it makes for a horrible person to make fun of people who had bad side effects or call them crazy or names. All medicine effects everyone differently...so you don't know what you are talking about and just shouldn't speak. I loved the Depo...I was on it for 7 years. It was great for me. I had big problems with my period and it solved that. I too had the side effects and extensive testing to figure out what was wrong...and was told it wasn't the Depo. I weighed 94 lbs starting...went to 130 over the 7 years...thought it was age...stopped it and lost 30 lbs in 3 months! I feel better, but went right back to period problems. My 37 year old brother had a massive stroke a few months ago...so now they don't want me on anything. While I feel so much better off of it...I would have stayed on it if I didn't have that risk, as long as I knew what was causing my horrible problems...and now just happy to know I don't have MS! Some tests indicated I did...so there is medical proof of the changes it causes to your body. No one is crazy here...it is a massive drug...some can take it and love it, some cannot...and when you can't it is for real valid reasons. F 35 7 years
 12/10/2006
 5  birth control, period pain No periods, increased sex drive, some bloating initially which passed after the first year I have had painful periods (including vomiting etc) since I was 14. I would end up having to take time off from school at first, then from work on a regular basis as a result. I also have had digestive problems since I was a child, which later turned into inflammatory bowel disease. The regular stomach upsets make the pill unsuitable for me as a reliable form of birth control. Depo has helped me with both the periods (I have had none since I started on Depo) which is fantastic, and also allows me to have a normal sex life with my husband without being terrified of getting pregnant! F 26 7 years
 4/27/2004
 5  birth control No periods:) Yeah!! Cured my migraines!! Minimal decrease in sex drive. Cured my migraines!!This drug is a god sent and with the wonderful side effect of no periods. Have gained 10 pounds over the 7 years I have been on the drug but feel it is due to age related change in metabolism and laziness to activity. This is a wonderful drug if you are a person who is frequently on antibiotics (like I was because of acne) because it does not interfere with the effectiveness of the drug F 27 7 years
 10/16/2004
 5  Birth Control Been on for 7 years, no side effects, great contraception for the busy women!!! F 23 7 years
 11/11/2004

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