DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Birth Control Weight gain (14lb), Agression, Painful breasts, Racing pulse, loss of sex drive and dryness. The first time I took it I had no side effects appart from no period which at the time I thought was great. I took it for about a year and stopped when I split from my boyfriend. My periods returned after about 3 months. A year later I started having the shots again and recieved 5 before i decided that the weight gain was intolerable and had lost my sex drive anyway so saw no point in continuing. My real problems started then. It took just over a year for my periods to return and they have been irregular ever since. My breasts are continuously swolen and painful and I am finding it impossible to lose the weight I gained. I am worried about the long term effects now that I am aware they haven't really a clue about the likns with cancer and ostoperosis. i wasn't given enough infomation before I was given it. I hope also that it won't effect my chances of concieving. Slowly with healthy eating and so on the side effects are wearing off but I regret not being properly informed before I took it. The idea of not having a period is so appealing when you are a carefree adolescent you doin't think about the possible conciquences. I wouldn't recommend it to anyone. F 26 15 months
 7/7/2005
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 1  Birth-Control/Stop Irregular Period I have taken the Depo shot for 15 months now, i was not made aware of all of the side effects. However, i was told about the mood swings and weight gain after i had my 1st baby. After one shot i noticed alot of my hair falling out, i assumed it was from the surgery or from having a baby, kept taking the shot and now 15 months later all my hair behind my neck is broken off to about 2 inches long. my hair was long, way past my shoulders. i never wear my hair up so i never noticed it was this bad, currently i have about half of my hair and have had to chop it off above my shoulders to make it look right, i have a gap close to my right shoulder where almost all my hair is broken off. I am severely depressed now because of my hair and my doctor swears its not the shot, dr.s do not listen i have tried everything to help my hair its not stress, not my shampoo, i take vitamins, and i am healthy. this is a horrible shot. I am 19yrs old and have no hair. I DO NOT RECOMMEND THIS SHOT TO ANYONE UNLESS YOU ARE ALREADY BALD. YOUR DOCTOR SHOULD TELL YOU ALL THE SIDE EFFECTS OF A DRUG, I MEAN AFTER ALL HAIR IS WHAT DEFINES A WOMAN FROM A MAN! F 19 15 months
 7/21/2008
 1  birth control severe loss of libido, mood swings, anger, more acne, weight gain (7-14lb), painful sex, vaginal dryness I have been off depo jab for 6 weeks now and am on the mini pill instead, after complaining about side effects to Dr. My libido is back to normal and I am not experiencing pain during sex. My skin is clearer and I feel calmer and am not experiencing the sudden mood swings. F 35 15 months
1X O		 5/11/2011
 1  control periods / endometriosis weight loss of about 22 lbs., extreme hair loss, terrible mood swings, emotional, break through bleeding, depression, loss of personality, terrible pain, loss of appetite. I have had endometriosis since I was 14. I have had surgery twice and been on birth control pills. After my second surgery in June of '09 I was put on this shot. At first it worked great except for a few break through bleeding every now and then. I would say after my second injection I began to loose weight. I weighed 112 lbs. gained 3 to be 115 lbs. then lost 22 lbs. to now be 92 lbs. I am 4' 11 so this is not a healthy weight for me. I also began to have periods exactly a month before I got the next injection, and they would last 7, 14, and one time it lasted 17 days! I have always had a lot of hair but now it just falls out in clumps I cant even run my fingers through my hair anymore because I am scared it will just pull more out. After my third shot my friends and family began to notice that I was not my bubbly outgoing self anymore, I was just so tired and never felt good. My doctor says that this would have shown up after my first injection, but that is not the case. She also said if you are prone to depression the shot will pull it out, but im telling you I have never felt depressed or as messed up as I do now. I would get so upset over every little thing and could switch from being happy to pissed off in about 2 seconds. I was just not myself anymore and am tired of it. I will not take another shot after this one is over I will just go back on the pill. F 18 15 months
 8/15/2009
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 1  Contraception Acne, oily skin & hair, vaginal dryness, night sweats, numbness/tingling in hands & arms when sleeping, swollen breasts, weight gain around the waist I got oily skin & acne from the start, assumed it would settle down but it never did. After the 5th injection the other side effects suddenly got a lot worse so I decided to stop taking depo. A year & a half after my last injection my periods are only now getting back to normal (I had them about every 2 weeks for 9 or 10 months). I also have swollen breasts & discomfort in my upper arms & legs due to swollen glands for the past 5 months. Thankfully the other side effects are gradually wearing off. Before I got my first injection I was told it could take "up to a year" for the depo to get out of my system, that my bone density could be affected through prolonged use & that my periods would most likely stop while taking it. I was not warned of any other possible side effcts. I've also had a sore throat that flares up every few weeks & leaves me feeling exhausted by evening; I don't know if it's connected to the depo but it started a few weeks after my first injection...the doctor says it's a low grade virus that my body has been unable to shake off. F 30 15 months
 12/6/2009
 5  Birth control The only "side effect" is not having any periods since I started Depo. I love Depo! I wish I could stay on it forever, but won't because of the increased risks of osteoporsis. F 21 16 months
 3/4/2006
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 2  birth control no sex drive, depression, mood swings galore! i got it when me and my boyfriend started getting really serious and about a year in i got really depressed and took everything out on him, we woulda broke up if he didnt have faith, then everything went back to normal and i've noticed i have intense mood swings and n=zero urge to have sex, it started really causing problems in our relationship and im not taking it again! i hope my body goes back to normal soon.. want this to be over F 19 16 months
1X AN		 11/4/2010
 1  Birth Control loss of sex drive, depression, mood swings I understand that some wome women have a great experience with depo. Mine has been a nightmare. I started having severe mood swings and I was depressed after my first shot. It would always get worse right after a shot. I loved not having a period though, so I stayed on it. I have now been off for 16 months and trying to get pregnant for the past 8 with no success.It doesn't help at all that I have no desire to have sex. I have heard so many stories of women who were unable to get pregnant for 2 or three years after depo. If you are considering the shot, make sure you understand the risks F 23 16 months
 4/29/2005
 1  birth control extreme hair loss, hot flashes, severe depression, weight gain, panic attacks, anxiety I do not reccomend, when i had my first shot it was brilliant my periods stopped and i lost 2 stone, had no other symptoms after a year on it a put 3 stone on and started having sever panic attacks to the point that it turned into aggraphobia. My hair is falling out and snapping off which really depresses me and im no longer the person i am, im so glad that im not alone, i thought it was just me. the hot flashes are unbearable sometimes i cant get out of bed because my legs hurt that much and feel wobbly. it sould be banned F 28 17 months
1X AN		 3/21/2012
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 5  Birth Control I started getting this shot for birth control, but now I will use it for as long as my doctor lets me, even if I'm no longer sexually active. I'm sorry for everyone who had a bad experience with this shot because I honestly consider this to be the greatest decision I've ever made. I'm 24 years old and haven't had my period for 18 months, literally, no spotting or anything. I never get any cramps, bloating, etc. My sex drive has INCREASED. My appetite has not changed. And my boobs got bigger. No negative side effects for me at all except for a SLIGHT weight gain. I've been on this shot for nearly 2 years and I've only gained 5 pounds, but I also eat like a truck driver so I can't even be sure where the weight came from lol. Also, some of that weight went to my breasts. A 32AA is now a 32A. It may not sound like much, but to those of us in the itty-bitty-titty-committee (lol!) it's a huge difference. I have had nothing but a fantastic experience with this shot. I have read everywhere that you should not get this shot for more than 2 years as it MAY increase your loss of bone density. I'm approaching 2 years and my doctor is a bit hesitant to continue giving me this shot, but I will do pretty much anything to keep getting it. I'll tremendously increase my calcium intake, do weight-bearing exercises, etc. Whatever I have to do to keep getting it. It's fantastic. F 24 18 months
 9/14/2008
 4  easy to remember/ prevent cramps weight gain (~25 pounds), MOODY, a little bit of acne, tender breasts, decreased sex drive I have been off of it for 14 months and have yet to have a normal cycle, which is extremely frustrating considering my husband and I are trying to start a family. During this time I managed to lose all the weight I gained (with exercise) and then some since I no longer have much of an appetite. My moodiness is just now starting to go away (my husband is very excited about that one). I also experienced about three months straight of nausea and extreme fatigue but I haven't had a problem with that for about four months. Oh, and my sex drive has come back. Overall I enjoyed being on it (aside from the weight gain), but have been frustrated coming off. ANYONE WHO IS CONSIDERING DEPO SHOULD KEEP IN MIND THAT THEY ONLY RECOMMEND BEING ON IT A MAXIMUM OF TWO YEARS!!!! F 22 18 months
 7/14/2008
 4  get rid of my period first 3 months constant bleeding, gained weight, NO SEX DRIVE, after the 4th time i just gained excessively, im in the military so i know im healthy, im not going to take it anymore F 20 18 months
 10/5/2007
 4  birth control, get rid of periods vaginal dryness, possible mood swings. I'm not sure if I had mood swings before so I won't blame it on the drug. As for the dryness, Reading others comments I realize that it's probably cause i'm on this shot. I get irritation and even one little hair in the wrong place makes it unbearable to walk. Otherwise I have no periods, no weight gain or hair loss, no more depression than before and i'm still a virgin so I don't know about sex, the drive it still there, though. I've been on the drug over a year. F 17 18 months
 10/22/2008
 3  birth control Viginal dryness (I'm 99% sure it's because of depo); aching and cracking joints and bones (I'm only 29, I feel like an old lady); difficulty maintaining weight; irrational moods. I have been on depo a few times for about a year each time and then come off it for perhaps a year. I do not have any bleeding with it which is one up side, the other up side is contraceptive. I'm convinced it's the depo which makes me feel depressed, angry and irrational, I wasn't like this before and I have no circumstances for feeling that way. I find I feel happier about 10 to 12 weeks after the injection and am seriously thinking of coming off it, and to hell if I get pregnant (although my boyfriend will not be pleased). I go to the gym 2-3 times a week, do yoga, and walk a lot. If I have a few days off from exercise my weight creeps up, even though I only eat 3 healthy meals a day and don't drink much alcohol. I'm also worried that if I stay on it for too long it will affect my fertility and I really want kids in about 2 years time. I have few alternatives: The pop pill gave me excrutiating breast pain, the mini pill cannot be prescribed because I have occasional migraine F 29 18 months
 12/13/2006
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 2  contraception Gained 20lbs in 18 months despite dieting and exercising; severe acne on my back; moderate acne on my face; hunger pains ALL the time; pain in knees (I think from the weight gain); two thick hairs growing out of my face; my Bs are now close to Ds, which would be fine if I were still 130 pounds! I went on the shot because I have had years of bleeding during intercourse that no pill was able to cure. Shot cured this problem but I am due for a shot in two weeks and not getting it. I can't wait to go off to see if I lose weight. My dr. said I wouldn't gain weight if I just watched what I ate. I have always eaten healthy and exercised so I thought this would be easy - not so when you are hungry all the time! The pill is not hard to remember to take. Just leave your pack next to your toothpaste. I did it for 15 years and will be doing it again until menapause! F 30 18 months
 11/13/2004
 2  contraceptive I have gained alot of weight and did not realise why as i have been eating a healthy diet and exercising. I have been getting bad spots and greasy skin, i feel tired all the time and my body aches, my ankles have swollen which i have never had before. My periods stopped and then started again. My breasts have got huge!! and they feel sore and swollen. I have terrible mood swings and feel sad and depressed alot of the time. I am thinking about not having the next jab seriously i cant go on gaining this weight F 40 18 months
1X AN		 7/4/2011
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 2  Birth Control and no periods! Weight gain. A stone and a half so far (25 pounds), which is a lot on my 4' 11 Good points - I haven't had a period or got pregnant! I have now gone back to the Family PLanning clinic and will be back on the pill next month (when my next Depo is due), the weight gain is not funny - I've gone up almost 3 dress sizes now (depending on the shop!) and I look 'fat'. The weight has gone on around my middle and hips - the danger area. Before Depo, I was an hourglass, and the weight would go on evenly. I was told by the nurse that I was lucky I hadn't put on any more weight - a few more pounds and I wouldn't have been able to go back on the combined pill due to higher risk of DVT. I would only recommend this if NOTHING else worked. F 31 18 months
 2/12/2005
 1  help ease menopause Loved it for first 3 shots...then had several UTI's, pain when urinating, severe depression, terrible head aches, swelling in hands and feet, ache everywhere (especially in back and ankle where I'd had injury in the past) I've been to several specialists, had a CT scan, a scope of my bladder, sonogram, they found NOTHING...then I go to St Luke's hospital and find out it's the damn depo. I am miserable...I miss lots of work, scheduled for hystorectomy next month and hope like hell I get back to normal when this poison gets out of my systom. F 46 18 months
 2/18/2009
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 1  birth control Mood swings, night sweats, dizziness, no period. I have not taken it for 2 years now and I am still recovering. I lost alot of weight, way too much in a short period of time, experienced mild depression and chest reduction. As a result I have stretch marks that I am finally getting rid of. Also I experienced an abnormal pap while I was on the shot. My hormones are still a little out of whack. I would not recommend this drug to anyone. Anything that alters your natural hormone balance this much is way too risky. 2 years and im just now feeling better. i am taking phyto-estrogen to balance my hormones out. Its working. Overall I think patients should consider every option out there before they start taking any medication. F 36 18 months
 1/1/2008
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 1  Birth Control weight gain, loss of sex drive, acne I went on depo after having my daughter in October 2005. My doctor recommended it since I was breast feeding. At first I really liked it. Then I noticed that I was gaining weight(after losing all of the baby weight) and had very little sex drive. I just attributed this to motherhood and change of hormones after pregnancy. I also always seemed to have at least one big pimple on my face which was not normal for me. my last shot was near the end of January 2007 and the good news is my face cleared up immediately but I still have not had a period since the shot wore off in April. We are trying to have another baby and have no idea how long it will take. Hopefully not too much longer. I WOULD NOT recommend this shot for anyone who wants to pregnant soon after stopping the shot. I have been very frustrated this summer and never plan to go on the shot again. I have done research and there are other options to women who are nursing. AVOID THIS AT ALL COSTS! F 27 18 months
 9/7/2007

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