DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Endometriosis Drastic mood swings, nausea, cramping, depression, memory fog and weight gain I decided to take the Depo shot after two years of taking birth control pills for endometriosis. At first I felt great, because I thought it was going to take my pain and heavy bleeding away. I was very wrong in that assumption. I gain at least five pounds within the first few weeks and I had extreme mood swings. There were days when I would break down bawling in my college classes, for no apparent reason and I spent a lot of my time away from people so I wouldn't take my temper out on them. I suffered from memory fog as well. I missed classes because of nausea, and did I mention the near constant cramping? While this medication did stop the periods, the cons of the drug are too much for the pros in this situation. I am most definitely going back onto the pill, after most of the medication is out of my system. F 19 3 months
1X O
10/14/2010
 1  Preparation for Essure procedure Severe mood swings, exhuastion, sore breasts, crying for no reason, nausea, digestive problems, irregular periods, weight gain, weakness, dizziness, loss of libido I only took this shot to prepare for having the Essure procedure done. The procedure went perfectly and I've had no side effects from that. But although I had the shot in early June, I am STILL feeling horrible. I have been so emotional and sad, feeling depressed all the time. I've had moments of extreme panic and I can't explain why I feel that way. I've been nauseous and sick feeling all the time now. My breasts are so tender. I have been absolutely uninterested in sex at all. I feel creepy-crawly feelings under my skin at times. I feel achy occasionally. I thought I was going crazy and I was seriously considering seeing a psychiatrist for the depression and then I found all these web sites talking about the side effects of going off the shot. I will never, ever let the doctor give this to me again. I am SO mad that I had to do it, but at least now I know I'm not going crazy. I will never let my daughter get this either. It's a really dangerous drug. F 42 3 months
1X day
10/17/2010
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 1  birth control i started taking this as birth control and to stop my periods. after a few weeks i started to notice pain in my ankles and feet. i thought nothing of it until now ive had my period for 23 days straight and not spotting but true bleeding. now my joint pain has become debilitating and i fear i will get up out of bed and colapse which almost happened last night. thank god i found this site because i now know the shot is to blame. i will never get it again and dont recommend it either. F 23 3 months
1X day
10/16/2010
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 1  not get pregnant Blurriness, shaking, gained 10lbs in 3 months, crying spells, mood swings, increased appetite, depression and the most horrible anxiety!! I had panic attacks almost every other day... I only got one shot and 2 months after being off depro. I'm still dealing with anxiety. I am currently seeing a therapist to help me get over them. I would NEVER recommend depo to anyone!! I regret not looking more into the shot before getting it.. F 25 3 months
1X day
10/17/2010
 1  Endometriosis Loss of appetite, severe hair loss, mood swings - depression Not enough information from Dr. before recommending the shot My daughter (age 14) was diagnosed with endometriosis and hemoragic cysts. Dr. recommended Depo to the endometriosis, she has lost 12 lbs, major hair lost no appetite hardly eats, very depressed. Abdominal pain. Has developed IBS because of it. This is our first and last shot. I wish I had more information about this before doing it. F 14 3 months
1X O
10/19/2010
 1  contraception Nausea, dizziness, pressure on temples, back ache, blurred vision, i was flinching at stupid things paranoia I have come off the injection now. I was told that the only side effects wer abnormal bleeding. My nurse laughed at me when i mentioned all my other side effects i now know i'm not crazy. F 20 3 months
1X M
7/7/2010
 1  Birth Control Extremely heavy and constant bleeding including passing of large clots, depression, aggression, joint pain, total loss of libido, loss of energy, hypertension. Taking Depo-Provera was worst decision of my life. I advise anyone considering it to really really look at the side effects and seriously think if it's worth it, but I promise you, it ain't! F 23 3 months
1X AN
7/15/2010
 1  To not be pregnant Makes you bleed continously, like every other day. It is very unhealthy. Low sex drive, Moody. I hate this depo-provera shot. I dont recommend it. F 21 3 months
150 mg 1X O
7/16/2010
 1  birth-control No period day after taking it. Worried about my chances to have children now! I had no period a year after stopping this drug. Then it slowly came back. It has been 3 years since I have had this drug and my periods just started to be regular. My fiance and I have been trying for a year to have a baby and its just not happening. I know its not him because he has 2 children from a previous marriage. I am starting to wonder if this shot made me sterile. F 20 3 months
1X day
8/1/2010
 1  Fibroid cyst Nausea, increased appetite, hair loss, extreme exhaustion, dizziness, weight gain, acne and lower sex drive This is the drug from hell! In June my doctor game me a choice of either a surgery or taking Depo to treat my fibroid cyst. I didn't want to have surgery so I decided on the shot. I was told the main side effect/risk was blood clots. As you can see I have had many side effects over the last two and half months. My summer has been ruined and my fibroid cyst did not decrease in size. I have lost total trust in my doctor after going through this experience. My doctor told me that I was allergic to the drug and couldn't take another shot. Really? I wouldn't take another shot anyway! My side effects seem to be a common reaction to the drug, not an allergic reaction. I will never take another drug without doing my own research on it myself. So I am left with feeling terrible, still have a fibroid cyst and needing a new doctor. Let's wage our own war against this drug and tell everyone how bad it is! The few satisfied people on this medication are really a small percentage. F 48 3 months
1X AN
8/21/2010
 1  Birthcontrol severe mood swings, deppression, eczema, severe headaches, from no periods while on the shot to constant periods for 6 months after getting off shot, crying uncontrollably over nothing. I had too many side effects to count. I have always had dry skin, but on this shot I developed series eczema where my legs would start bleeding becuase I would itch them so much in my sleep. I honestly became a crazy person with the constant mood swings and would get so angy over the tiniest things that I would just have to grind my teeth to keep from screaming I was so mad, and I have always been an easy going, laid back person before the shot. I hated who I was becoming. I also gained about 40 pounds in 6 months and coulnd't control it no matter how much I worked out or dieted. I am still struggling with the weight and I have been off the shot for over a year. I would NEVER recommend this shot to anyone and STRONGLY urge anyone to get off of it as soon as possible. I don't understand how this shot can be legal. Also the doctors where I got this shot didn't warn me of any of the side effects which isn't right! They said that there weren't any more side effects with the depo than any other birth control which is NOT TRUE!!!! This is the devil's drug. F 21 3 months
3 shots 3X O
4/30/2010
 1  Fibroids immediate forgetfulness, irrational thinking, depression, fatigue, explosive anger, mood swings, blurred vision, dizziness, constant bleeding and menopause I will NEVER, recommend this drug! It's terrible, and it should be taken off the market! I feel that additional medical research will not improve this drug! I got my first shot in January 14, 2010. An hour later, I was forgetful, paranoid, anxious & confused. I skipped my menses that month. In February, I started to spot, this then increased, bleeding more throughout the months. There were times when I passed very large dark red blood clots. I visited my doctor and explained my symptoms, as well as my altered state of mind. I asked him if there was something that he could prescribed to stop the bleeding and to counter act the drug to get it out of my system. He replied I would need a "D"- for some reason, he didn't complete the last part of his sentence, he was going to say a D & C. He changed direction and said that I would need to take another shot. I told him there was no way that I would take another shot and how in the hell could he have the audacity to recommend that I take the shot again even after I've told him what I'm been going through. He called me later on that night (feeling guilty) to check on me, he said "I don't blame you for not wanting to take another shot." I feel extreme anger, I have a drug in my system that has to wear out. April 15 - 25th I had a very heavy menstral with large dark clots. From April 26th - 29 nothing, now today, the 30th I went to the restroom and noiticed that I'm starting to spot. Well, I thought all F 49 3 months
30 mg 1X M
4/30/2010
 1  My sister was prescribed it Horrible anxiety! Moodiness, Even more irregular bleeding Hi, im a concerned, outraged brother that found this site after recieving no help from the "glorified, all-knowing Doctor." My sister started the shot due to heavy bleeding and irregularity. Her doctor put her Depo and after a few weeks of treatment she started showing signs of anxiety. So much so, she would regularly have panic attacks during class time. These attacks became so severe, her 4.0 gpa dropped to almost 2.0 because she couldnt sit through a single class. About a week after these side effects began, she saw her doctor again, but her doctor was clueless as to why she might be having these symptoms, and eagerly dismissed the idea that Depo could cause someone such harm. Really wish doctors were more concerned with helping people... M 22 3 months
1X O
6/23/2010
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 1  avoid getting pregnant PANIC ATTACKS! I am now 27, I got a shot of this when I was around 20. Shortly after I got the shot I remember I had shortness of breath quite often, which led me into having panic attacks and hyper ventilating. I went to the E.R. 2x in one week. I'm so glad I came on here because I was about to go on this again, thinking the panic attacks were coincidental....now I remember how much I hated the shot and couldn't wait for it to leave my body. I remember not being myself at all...locking myself in my room and sleeping all the time. It was horrible. Actually think I'd rather get pregnant than go through that hell again. F 27 3 months
1X AN
6/28/2010
 1  BC loss of about 1/3 of my hair lost 10 lbs in fist month (went from full B bra size to A) to much to list...... 1 shot feb. 2nd 09 (1year 4mts ago) OMG PLEASE HELP!! when will this END!!!! lost 10lbs first month of taking it and lost a full cup size! I have gained the 10lbs back but my breast did not come back w? that!! periods are still all messed up, my hair still falls out, I run 3x a week to stay active and tone up but my body just wont tone up... my breast are still @ a A cup but Im always still so Fatigue..... when I wake up Im sleepy, I need a nap @ about 1 pm and 6pm..... I noticed all this about a month after I got this shot! If you have any advice please let me no..... I've tryed talking to my DR but she blows me off and says it will get better BUT WHEN???? I don't no what to do any more I don't like living like this! I have a 6 year old little boy who wants me to play w/ him and I just can't Im always so sad and angry (oh yeah mood swings to) And my little boy says mommy why are you always so mean) yep thats how I know its the depo!! HELP PLEASE! F 26 3 months
1X O
6/28/2010
Email
 1  Responsible Married Woman During: nausea, headaches, excessively tired, bled for 2 of the first 3 months, acne and eczema increased, reduced libido After: no spotting or period at all since the end of the shot (it has been a little over 2 months), acne and eczema extremely unbearable, joint pains especially in jaw joint, greatly reduced libido, full body aches, random skin rashes, bloodshot eyes that will not go away I am a 27 year old at 5'7" 130 lbs. and healthy with the exception of this dreadful Depo in my system. This is the worst thing on the market for people trying to be responsible about having children when they still want to have children someday. I only see one reason to take Depo and that is to treat PCOS or for sterilization. My husband and I want to have children someday. I took the Depo because I wanted to be period free during our one year wedding anniversary in Mexico. Now, I have had no menstrual cycle and am concerned that I may need hormone therapy if we ever want to have a child. HOW TERRIBLE THAT THIS IS APPROVED SAFE!! SAFE!??? Really? From all these experiences, I would never imagine to call this SAFE. TAKE THIS OFF THE MARKET AND DOCTORS, PLEASE FULLY EDUCATE YOUR PATIENTS AND TALK THEM OUT OF THIS POISON. F 27 3 months
1X O
7/2/2010
 1  prevent pregnancy This shot made me extremly depressed. Thoughts of suicide major mood swings. Before i got the shot my husband of almost threee years and i got along great and after he threatned to leave me because he coulc not stand my mood swings all the time. I swear this shot makes you bi polar. I would not recommend this shot to anyone i got on it because it was the easiest method of birth control but I would get my tubes tied before even thinking about taking this shot again. THIS SHOT SHOULD BE BANNED FOREVER! This shot made me extremly depressed. Thoughts of suicide major mood swings. Before i got the shot my husband of almost threee years and i got along great and after he threatned to leave me because he coulc not stand my mood swings all the time. I swear this shot makes you bi polar. I would not recommend this shot to anyone i got on it because it was the easiest method of birth control but I would get my tubes tied before even thinking about taking this shot again. THIS SHOT SHOULD BE BANNED FOREVER! F 26 3 months
1/26/2010
 1  birth control Three to four week long periods,spotting every day since shot,worsened depression and mood swings,heightened anxiety,PMS cramps 24-7,bloating,painful gas,headaches,backaches,decreased libido (mentally,at least)lack of physical pleasure from sex,VIOLENT ANGER ISSUES,paranoia,loss of interest in going out or being near people (even on line),did i mention the uncontrollable anger I started taking this when my baby was 4 months old to prevent pregnancy and also, I'd been told it would make my uber painful periods go away. It was supposed to be safe for my age and being a smoker and history of blood clots,depression, and anxiety. I was lied to. This stuff has been toxic to me,I have wanted to die the last three months,and I have everything to live for. I am not me anymore and I am angry because I did some research and the medical establishment just downplayed my fears and assured me the only true possible side effects were loss of a period and weight gain. Maybe for a small segment of women, but it has been a nightmare for me. Instead of a week of cramps and a week of bleeding, I get a month of cramps and mood swings and 3 to 4 weeks of bleeding. Their solution is to keep getting the shots until the periods stop.Never mind my pre existing depression,bipolar,and anxiety have me near a break down when I was doing well postpartum before the depo. My stepmom gripes that they took her off the depo and she loved it,so it does work for some, but for those like me who were ill advised and mislead, this stuff is poisonous. I'm not getting another shot,ever, and I personally think with this many bad side effects it should be taken off the market.At the same time, it has been a life saver for some. The happy medium would be health care providers educating patients THOROUGHLY about what COULD happen with this drug. Even if it only happened to one person. F 37 3 months
1X M
2/27/2010
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Patient History
 1  Birth Control More hunger (weight gain as a result),fatique, no sex drive, headaches, no period for 3 Mo. At first I didn't experience any side effects other than no period (not even spotting). After the first missed period I started noticing an increase in headaches, fatigue, lack of sex drive. I gained 10lbs. in 3 months and the fatigue was so disturbing that I decided right away this was not the birth control method for me. What's been even worse is going off of it. I've had non-stop spotting for 4 weeks now, swollen breasts, cramping. It's worse than the changes I went through during pregnancy. This cannot be good for your body -- steer clear of this birth control alternative! F 43 3 months
1X O
2/25/2010
 1  birth control Basically every side effect from the drug excpet weight gain This is the WORST drug EVER! I used to be one of those people that thought eh reviews are reviews theres no chance anything will happen to me...I'm 19 years old and my boyfriend is in the marines so I hardly see him enough as it is. So I thought the shot would be perfect because I wouldn't have to take a pill or anything cause Im bad at taking pills. I got the shot December 9, 2009. Everything was fine until christmas day. Everything started going downhill. My period started which I thought wasn't a big deal because it was to be expected and is the most common side effect. Well my period was a monster and I used to have bad cramps before but this shot my cramps 3 times worse. Then I started getting dizzy spells out of knowwhere. After a week the bleeding went away and then IT CAME BACK! It came back the second week of January and I've been bleeding ever since (today is Feb 26) so I've been bleeding non stop for about two months! And I've had the worst stomach pains and cramps of my life. As of now I'm still extremely dizzy, still bleeding, leg cramps, HORRIBLE MOOD SWINGS! I can cry at the drop of a hat over anything. My acne was starting to clear up before the shot but I think it has gotten worse since I started the shot. The only up side is I haven't gained any weight at all BUT it is impossible to lose weight on this drug. I exercise about 5 times a week and I've recently lost 50 pounds and could was losing weight so easliy. But ever since I got the shot its like frozen my F 19 3 months
1X O
2/26/2010

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