DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 2  Birth control Weight gain, depression, always tired, hard time getting pregnant after 5 years of taking it I loved not having a period for 5 years but, now that I am married and we want to start a family I am having a really hard time getting pregnant. If you are on depo and are thinking about having a baby anytime in the next year get off of it now. When I first got off of depo for the first 2 months you get all of the symptoms that you are pregnant. Morning sickness, tender breasts, all of that good stuff but believe me your not pregnant. I was on another web site and the average time it takes you to even get a regular period is almost 2 years. And it took most women that I talked to 3 or more years to get pregnant. I think that have a baby when you want far out weights having your period once a month. F 23 5 years
 1/20/2005
 1  Endometrosis Weight gain, Acne, headaches, body aches, mood swings, hair loss, anxiety, hot flashes, night sweats I'm taking depo for Endo, those of you who have Endo know how painful having a period is. but I'm looking into other options for Endo because the side effects of this drug are getting unbearable. I feel like I'm 80 years old, my body feels like I have arthiritis all over, I can't sit, stand or lay down for any length of time because of the pain, No matter how little I eat and how many miles I walk, I can't get rid of even one pound.. Im tired of feeling like crap, There has to be a better medication for endo. I would not recommend this to anyone, just remeber to take your pills or get the patch. F 27 5 years
 4/13/2005
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 1  Birth Control I experienced anxiety, depression, weight gain, loss of bone calcium even though I took calcium supplements, irregular periods, and estrogen dominance. After discontinuing my injections, I have been experiencing pregnancy symptoms even though I am not pregnant. My body had started to mimic menopause while on depo which is what worried me and caused me to discontinue it. I am now worried that my ovulation and fertility will be damaged permanently from this drug. I was not informed that Depo should only be taken for 2 years, after being on it for 5 I am horrified as to what this has done to my body. When I started Depo I thought wow, I won't get pregnant and my periods will stop. After 5 years of injections I am now worried that I will never get my periods back to normal and my chances of having children will be compromised. If someone had told me this when I first started I would have never agreed to let a doctor inject this into my body. F 18 5 years
 3/13/2005
 1  prevent pregnancy 40 lb weight gain,unable to lose it w/diet and exercise. Bloating all the time, back, neck and legs hurt. Major depression, loss of sex drive, panic attacks, headaches, and fatigue. Warning: if you think this is a great drug...just wait. These side effects will eventually get to you! It took me 4yrs and now I have been in pain for 1 yr and still in pain after 4 months off of it. It will ruin your life. It needs to be taken off the market! F 36 5 years
 2/10/2005
 1  Birth Control Severe acne, Weight gain, Anxiety and Panic Attacks, Depression and Sleep Issues, Breast soreness (Increase & Decrease in size), Severe mood swings including an increase in anger. Body aches, back and legs and I now suddenly have allergies, which I never had. PLEASE READ ME!!!! DEPO ALMOST RUINED MY RELATIONSHIP!!! I started taking this drug when I was 21 and started off having no problems. My period stopped within 6 months and I have not had one for 5 years, except for occational spotting near the time of the shot. However, the past 6 months have been HORRIBLE! My face broke out with acne 3 shots ago. I have never had acne and at 27, found it shocking. after spending hundreds of dollars on products and facials, I went to a dermatologist and cosmetologist- they both said it was the birthcontrol. The Acne was the least of my problems- The SEVERE MOOD SWINGS have been unbearable! I have never had mental or psychological issues. On Depo I burst out crying- am depressed most of the time (and I'm normally a very happy, energetic, outgoing young woman), I have outbursts of anger and I feel tired ALL the time. I have always had confidence and now I have never felt so bad nor looked so bad. My last shot was 3 weeks ago- and my arm still hurts where I was injected! I truly hope someday I will be back to normal- this has put such a strain on my relationship- I'm lucky to have a man that recognizes that this is NOT the real me, but the hormones that have taken over my body. IF THERE IS ANYONE THAT KNOWS OF A GOOD ALTERNATIVE BIRTH CONTROL OR A WAY TO HELP MY SYMPTOMS, PLEASE ADVISE...To everyone else, I wish you well! Please Don't let this happen to you! F 27 5 years
 2/16/2005
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 1  birthcontrol osteoporosis I was on depo for the duration of 5 years about 10 years ago. Only this week did I find out that I have osteoporosis. When I researched on the internet, I had NO clue that the two were even associated. Being naive at the age of 16 has caused pain now 14 years later F 30 5 years
 7/27/2007
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 1  birth control Weight gain, bloating, loss of sex drive I have gained 40 pounds in 5 years. Complete loss of sex drive. And I wake up every morning bloated. Most people weigh the least in the morning, and I weigh the most in the morning. My rings and watch are cutting into my skin every AM. Then, once I get up and moving, I start peeing and peeing and peeing. Every 15-30 minutes. Then I feel pretty good by noon. I weigh my least in the afternoon. I don't know why I have tortured myself for so long. I haven't had a shot in 3 months, but it takes 6-12 months to leave you system! Do not take Depo Provera!!!!!! F 32 5 years
 3/6/2009
 1  birth control No noticable ones the first two years, except I never had a period after starting the Depo the day I left the hospital after my last son was born. After this I gradually put on 20lbs which I couldn't lose no matter how much I dieted or excersized. Then the depression kicked in every morning. I couldn't figure out what was wrong. I had a great life, but was depressed every morning. My hands fell asleep at night and this woke me up. Lots of insomnia. Acne, which I hadn't had since I was 13yrr old. Hot flashes and sweating. I have been off depo since Oct. of 08'. I no longer have insomnia, am dropping the weight with diet and feel none of the heavt depression. I still haven't had a period, but I understand it may take up to two years to come back. My doctors only informed me of bone density issues and never mentioned these other side effects. Please investigate before taking. Not having a period is cool for 5 years, but the side effects weren't worth it. So glad to be over them. F 44 5 years
 1/9/2009
 1  Birth control Weight gain, migraines, extreme mood swings, and uncontrollable hunger. I have been on this medication for 5 years now, and I have been experiencing menopausal effects. I have hot flashes every night, I have gained 80 lbs since I have been on the medication, I have lost interest in sex, I have to use a lot of lube during intercourse which irrates my boyfriend because he don't like the residue feeling during and afterwards, I have become a very hateful person. The slightest thing will make me explode into a fit of rage at the drop of a hat. I have had to have multiple surgeries that are unusual for a person my age. I have severe headaches everyday that no medicine will subside. Depression comes and goes and is so random and at the worst of times. I feel as though that anyone who considers this drug may really need to do some research and ask their doctor to be 100% truthful about it and its side effects. I was unaware of the bone density loss that may result and was told at one of the most awkward of times and was instructed to wear estrogen patches for 6 m F 20 5 years
 11/22/2008
 1  Prevent Pregnancy& had a low blood I was satisfied the whole time I was on the depo shot but last March I got off of the depo shot and it took about a year for me to start having periods when I first start having Periods, I got a cyst on my ovaries now I dealing with BV it keeps going away and coming back it totally ruined my sex life. my periods are irregular I've gained so much weight. I wish I never got on the shot and I do not recommend it to anyone and if you are on it I recommend get off it now I have done a lot of research on it and I have come to realize that a lot of the symptoms that I'm going through, a lot of other people that have been on the depo shot are dealing with the same thing. F 21 5 years
 5/6/2015
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 1  birth control Coming off depo hard pelvic area like in pregnancy nipple tenderness dry no sex drive depression mood swings no period last shot was due June 7 2013 F 34 5 years
30 mg		 10/22/2013
 1  Birth control I had weight gain and severe mood swings. I had no sex drive at all and extreme dryness if I did try to have sex. I quit taking depo about 1 year ago and am finally beginning to be normal again. I managed to ruin my relationship with my boyfriend because of my lack of sex drive and my anger. Luckily he came back after I got off the depo. I wouldn't recommend this to anyone. F 43 5 years
 6/8/2008
 1  Couldn't remember to take pill Lack of sex drive fatigue, very moody, and weight gain I was on the depo provera for 5yrs. I couldn't figure out why I would be so tired, and have a lack of sex drive, until I did some research. I finanlly made up in my mind this year in March that I would never take another shot. If I would have known that this shot would make me feel so horrible I would have never took the first injection. My relationship was hanging on by the threads because I didn't understand what was going on and he didn't either.It is going on 5 months since i have had any birth control, and I feel as though I am getting better, but my body still isn't where it needs to be. Sometimes I feel as though I am a 50 or 60 year old woman. I have been having back trouble for the last couple of years, the doctors really can't see that I have done any damage to it. Although I seen a chiroprator and he told me some diagnosis in some hard to understand terms. There are mornings where I can't get out of bed, and I just cry. It seems as if no one understands. I don't know if the F 23 5 years
 7/30/2008
 1  Birth Control Extreme loss of libido, depression, fatigue, loss of periods Originally took this a few years ago and was very happy with it at the time. Came off it due to stories of osteoporosis, tried the implant which just made me bleed constantly. Have gone back on Depo but am in serious relationship now which I wasn't when first taking it. Have found that it has reduced my libido to nothing. Have no interest in sex or anything relating to it. Have found studies to suggest links to cancer and that this drug is used to treat sex offenders to reduce their libido. I recommend really reading up about Depo and not just taking what your Doc says as gospel. I'm coming off the injection and will be trying to find a pill that suits me now. F 28 5 years
 5/27/2009
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 1  birth control severe weight gain, decreased sex drive, hypothyroidism, chronic yeast infection, dryness and vaginal irritation, pain with sexual intercourse, very irregular periods I took depo for aprox 5 years which was the biggest mistake of my life. I continue to have sig. problems after stopping this shot. I have not been able to get rid of chronic yeast infections and dryness in the vaginal area since being on the shot. I also continue to have significant pain with intercourse. I now have multiple folicular systs and am having difficulty trying to become pregnant. My weight gain due to the shot has also caused multiple problems. Overall this has been a very nasty drug and has caused multiple ongoing problems even though I have been off of the shot for almost 5 years now. Would like to know if there is a class action suite being persued against this drug. F 31 5 years
 5/31/2009
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 1  Contraception Weight gain (4st in total), complete lack of sex drive, Thrush, Depression, Panic attacks and many more! I was on Depo due to not being able to have the pill. I came off it in July 09 and started my first period two weeks ago after not having one for five years. I has not stopped since. I currenlty have really bad cramps, feel dizzy and sick, totally exhausted and very tender breast.My symptoms seem to be getting worse and NHS Direct say that this is normal after coming off Depo!The worst side affect for me was the painful sex and thrush which nearly wrecked my long term relationship. I would advise anyone who is thinking of going on Depo to seriously consider other options. If I could turn back the clock I would not have gone on it!It maybe the easy and lazy option but in the long term you pay for it! F 22 5 years
 12/10/2009
 1  Birth Control No period, head aches, body aches, joint pain, anxiety, weak, back aches, sensitive skin, weight gain, hair loss, depression, mood swings, low sex drive I was put on the shot shortly after having my 1st child, whom i got pregnant with while i was on the pill(at 17 yrs old). I was on the shot for 3 years with no problems, my doctor told me it wasnt reccomended to recieve the shot more than two consecutive years and that i should consider switching to a new method. So it was back on the pill, shortly after, while on the pill, i became pregnant with my 2nd child. After she was born i insisted i be put back on the shot since it seemed to be the only method that works and it was just a bonus that i had no period. That was 2 years ago, and I am still on the shot now but have recently noticed over the past year my body has felt like its falling apart. I feel very weak, and achy, my skin is very sensitive, ive had major hair loss, my weight is at a halt and no matter what i do eat healthy, eat junk, are active or do nothing, its at a stand still. I've had horrible pains in my ankles, knees, and wrists. It hurts to walk down the stairs, sometimes i cant even hold my 30lb child because i am so weak. I always blamed this on bad diet, not enough vitamins and what not, but the more i read into depo, the more im starting to believe that im not falling apart, the depo is destroying me! After 5 year of what i thought was a miracle drug, last week was my last shot. Im going to give my body some time to recooperate and see what happens from there... F 25 5 years
 12/12/2009
 1  contraception i was on this jab for like 5 yrs and had cramoing,loss of sex drive loss of all drive cant sleep cant do mutch lack of motivation i stopped taking over 2yrs ago and still trying for a baby i alredy have one daughter so its the drug in my sysem i wouldent recamend long term use atall F 24 5 years
 4/4/2006
 1  unwanted pregnancies 20lb weight gain, breastpain, headaches, hairloss, decreased sex drive, period stopped. I,ve recently developed dengerative disc disease in my neck and spine of 2006, I've been of the shot 2yrs. I was taken of the shot by my doctor because it's making women's bones so brittle, when I first started using the shot I wasn't informed that long periods of use would lessen bone density I've been living in chronic pain for a year going to therapy and seeing a chiropractor if my condition doesn't improve I'm thinking about filing a lawsuit I wouldn't recommend depo to anyone they need to take it off the market. F 36 5 years
 8/6/2007
 1  Birth control rapid weight gain (5 lbs. on average each time I got the shot), loss of sex drive, migraines, mild depression F 31 5 years
 7/19/2006

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