DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 3  Endometriosis Weight gain, painful sex, mood swings, irritability, hot flashes As far as treating my endometriosis, this has been a miracle cure! No periods, no pain. After battling endo for upwards of 22 years, the disappearance of pain has been an unbelievable experience. However, I am becoming increasingly torn over the continued use of Depo because of my seemingly escalating array of side effects. I have gained 15 pounds in a year, I seem tired all the time, and sex with my husband of 20 years is so painful that I am avoiding it at all costs...very unhealthy for my marriage. I have 5-year old twins and a 3 year old so I can attribute some of my irritability to the general turmoil of dealing with a houseful of small children but I really feel that I am unrationally volatile in a way that I hadn't been before. I'm having serious doubts about my miracle benefits when balanced against my seeming costs. My pain treatment against my mental well-being and the effects on my family! I really don't know what to do. F 41 1 years
 1/8/2007
 3  Severe Cramps I had a great increase in weight. In the matter of 3 months I gained about 20 pounds. I constantly feel tired and when I do any simple physical task I have shortness of breath. My sex drive has lowered dramtically to the point I just do not care. Although, I love not dealing with all the painfull cramps I just can not deal with side effects that this shot comes with. F 24 1 years
 1/10/2007
 3  birth control Bled for 1 month straight in the beginning and had to take prescribed estrogen pills for a week to get back to normal. I was on it for about 1 year and gained approximately 10 pounds during that time. I know it was from the shot since the weight gain was around the mid-section (never happened before) and i had been on many different brands of the pill without experiencing this side effect. I lost the weight within 6 months of being off of it without dieting. Excellent form of birth control if you don't mind the weight gain. F 26 1 years
 7/6/2005
 3  forget too often to take pills Depression, anxiety, nervousness, hot flashes, some fatigue, libido loss I gave it a rating of 3: which is Somewhat Satisfied because I felt both satisfied and disatisfied with it. On the up-side, I gained weight (before my max weight was 119 lbs.) Now I weight about 140 lbs. With the weight it has filled me out in places that needed filling out, so my body looks better (except for a little pudge in the stomach). Another good thing is that I don't feel like I have to worry every time my husband and I have sex, which is a plus for both of us since we are not ready to have children yet. But on the down-side, it doesn't do anything for my irregular menstrual cycles, I feel depressed more often and that depression seems intense and I feel that my anxiety has intensified while being on this drug. Some nights I would go to be in warm PJ's because I felt chilly only to wake up the next morning and be sweating like crazy. So far, I don't know whether I will continue to take the drug. I feel that the deep depression I feel sometimes outweights the benefits of ke F 21 1 years
 2/19/2006
 3  Avoid hysterectomy for Hyperplasia Mood swings, loss of libido, extreme vaginal dryness, painful intercourse After extended bleeding and spotting for the first few months, all seemed okay except lack of sexual interest. Mentioned to doctor who said it was probably stress. It did stop the pain of suspected endometriosis. After a more than a year, the dryness and pain durning intercourse has made me reconsider the hysterectomy. It's scheduled for this Tuesday. I felt 100% better hearing that others had similar problems and that it was not all in my mind! F 46 1 years
 10/15/2006
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 2  Contraception Chronic bladder infections, spotting, vaginal dryness, painful intercourse While it was nice to not worry about getting pregnant, the constant bladder infections I suffered made my life very painful. I had an average of about two a month, and was prescribed far too many antibiotics, at which point the antibiotics stopped working. I finally saw a specialist and he told me that Depo was most likely the cause of the problem. Sure enough, the minute I went off it, the infections occurred less and less. I now struggle with infections again on Micronor, which contains the same hormone, so I suspect it is the same problem. F 22 1 years
 7/20/2006
 2  prevent pregnancy Depression, dizziness, fatigued, weight gain, very heavy menstruation even after a year. I've been on my period for 2 months, and I have been getting the injections for a year now. I've decided to switch birth control methods. F 17 1 years
2 cc's 1X O		 9/2/2010
 2  Birth Control Hard to regulate weight gain. Mood swings were more extreme after about a year(2nd time on Depo). Getting off of Depo has been a stretch as well. My hormones seem so far out of whack that I'm experiencing insomnia and a multitude of gastrointestinal issues. I am 2 weeks past when I should have had my last shot and the insomnia is awful. I'm hoping that as my body re-adjusts that my sleep issues fade and my energy levels come back. F 30 1 years
 1/30/2009
 2  birth control i had bleeding or spotting EVERY single day while i was using depo. other than the bleeding this drug was great. i didnt have to worry about taking a pill every day and i didnt gain any weight at all (in fact, i lost weight). but the bleeding was annoying and unbearable. i put up with it for an entire year hoping it would go away because the other people i knew who used this said they didnt have a period at all (which would have been nice). F 27 1 years
 9/20/2003
 2  Birth Control Hard to control weight. I had always had a problem with my weight so I did not think much at the time. After the first shot I pretty much bled (not hard) every day for 1.5 months. I tried the second shot and the bleeding stopped. I decided that due to my age and that I smoke I better stop birth control all together. So I was on it 1 year. Since then, I had to be on a 3 month leave from work because I had an emotional breakdown! I never put 2 and 2 together before I saw all of this depo info, by accident mind you. Maybe it is what caused it! Beware! F 36 1 years
 6/17/2007
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 2  Prevent pregnancy I am constantly fatigued. My muscles ache, all over my body. No hair loss. Weight gain (10+ lbs). I have had -3- shots total. I feel like I have been beaten with a stick! I am always tired, insane headaches, depression. Since I have been feeling this constant fatigue and NO motivation to get out and do anything, I decided that it MAY be because of the Depo shot. I do not take any other drugs. I do not have horrible acne, but I have gained wieght. I can feel, about 12 hours after the shot, horrible bone pain. I have to lay down and cry it gets so bad. I am DREADFUL, EVIL and so very mean for about a week after the shot and then I even out. My husband understands, but he also knows that I try to control my bitchiness. I don't want to be mean to him. My biggest complaint is that I am so very tired. I ache, I can't concentrate like I used to (not good for a philosophy major who MAY go to law school), I find that nothing helps. I take Advil PM to sleep, and I want to sleep constantly. I used to do things with friends, and my hubby, but now all I want to do is sit around in my robe and either cry or sleep. I am not getting the next shot, which is due in August. I need to lose weight (I was neve F 37 1 years
 7/8/2007
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 2   No Period for two months then I have a period for a month, weight gain, fatigue, muscle soreness, vaginal dryness during sex I originally thought this would be great because I wouldn't have to worry about taking a pill. It gives me light long periods. I bleed for like a month till I get my next shot then it stops for two months. I've been eating right and excercising and still can't seem to lose weight. Not ideal for me at all. All together I have taken it for a year but with a break and a pregnancy in between. F 22 1 years
 6/1/2009
 2  not to get pregnant, ease cramps weight gain, insomnia, loss of sex drive, irritability, lack of energy was on it for bout a yr n a half, i had my last shot in Nov. 08, shoulda had my nxt 1 in jan but no longer had insurance & no longer wanted it... still have not started my period,(if any1 else had this prob plz email me n let me kno how it ended up workin out for you)and my new doc is iffy on puttin me on new birth control bc of that, i gained a total of 20 lbs wile on it, wen id get my shot for the nxt few days id have bad cramps n feel nauseated... i overall did not like the way it made me feel! also ive heard it causes infertility, jus wondered if that happened to any 1? F 19 1 years
 4/25/2009
 2  Birth Control Extreme weight gain (40 pounds), sex drive remained in tact This drug causes weight gain and decreased bone density. Immediately after switching to the pill, I started to lose weight. F 22 1 years
 12/7/2009
 2  unexplained bleeding I'm taking depo and its horrible, i have unexplained bleeding and had my period for 7 months last year. so they put me on pills which didn't stop my bledding, They decided too put me on depo, My mom agreed and i've been on it a year. I was 138 when i put on this shot and gained 30 pounds. I don't eat very much i munch during the day. but i was wondering if this is normal. My GYN said that I am supposed to be gaining weight but im not sure im suppossed to be gaining this much. And it is embarrassing because it is noticable. its horrible. anyone else have this? F 15 1 years
 7/6/2009
 2  Pregnancy prevention Loss of period, vaginal dryness, muscle pain (only a few days after getting the shot), and painful sex After being on the shot after a year I am going to switch to another method because the vaginal dryness and painful intercourse ruined my sex life. F 20 1 years
30 MG		 5/23/2020
 1  preventing pregnancy No period,and when they come it's either too little like spoting or alot and very painful periods,during the 1year I gained a lot of weight which Icant seem to loose,its been 2years since I stopped using depo and still my body has not gone back to normal Any one thinking of starting depo should think twice. F 30 1 years
00		 5/18/2016
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 1  Prevent pregnancy I've experienced migraines,fatigue,muscle weakness,scoliosis in my spine, muscle spasms in my entire body, sunken eyes, muscle loss, fainting or passing out anytime F*ck depo shot never get it especially with a hormone imbalance F 22 1 years
1 1X day		 2/22/2023
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 1  the boyfriend wanted no periods mood swings, first month period lasted almost 2 months then no period at all. tired all the time. i didnt have a lack of sex drive that bad, even tho it greatly increased when i stopped taking it, i came here looking for information on the side effects when stopping the shot. i still havent had a period and its almost been a year since my last shot. i would say to anyone thinking about the shot DO NOT take it. the time shown on how long i took it is counting even when i stopped taking the shot, i only had 3 injections F 21 1 years
 7/2/2009
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 1  Birth Control Hunger, Weight Gain I started depo july of 2003 and stopped the injections a year later. During and even still to this day I still feel very hungry all the time. It really sucks and it seems like since I started the shot everything tastes completely different. So it's 6 years since I've stopped taking the shot, and I am still constantly starving, all the time, and when I eat nothing seems to satisfy my taste buds. I have gained 35 lbs. and it is very hard to control the hunger and lose the weight. PLEASE IF YOU ARE CONSIDERING THIS BIRTH CONTROL, RETHINK YOUR OTHER OPTIONS. M 23 1 years
 9/16/2009

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