DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  birth control decreased sex drive, non-stop heavy bleeding, excessive weight loss, hair loss, photo sinsativity- causing small blisters on my skin exposed to the sun, hair groth on chest, pannic attacks, and probably more that i was unaware of due to more severe side effects! I TOOK DEPO TO PREVENT GETTING PREGNANT A SECOND TIME. I WAS ONLY 17 AN HAD NO IDEA OF CHECKING SOMETHING OUT AND I TRUSTED MY DOCTOR. I HAVE TYPE ONE DIABETIES AND HAVE BEEN INSULIN DEPENDANT SCINCE 15. I BECAME PR EGNANT AND THEN HAD MY SON. MY DOCTOR INSTISTED I TAKE DEPO AND (NOT HAVE ANY MORE KIDS) DUE TO THIS AND OTHER HEALTTH PROBLEMS. SO I DID. WITHIN THREE DAYS I COULDN'T EVEN GO OUTSIDE IN THE SUN BECAUSE EVERY TIME I DID I GOT BLISTERS. MY HAIR BEGAN TO FALL OUT SO FAST I STARTED TO GET BALD SPOTS. MY DOCTOR TOLD ME THAT IT WAS HORMONAL AND THAT I NEEDED TO GIVE IT TIME. I WAS SOAKING ABOUT A PAD EVERY 2 TO 2& 1/2 HOURS. ONE THING IS FOR SURE IT WORKED FOR BIRTHCONTROL! THERE WAS SO MUCH BLOOD I WOULDN'T EVEN THINK ABOUT SEX. I STILL HAVE SCARS ON MY SKIN FROM THE BLISTERS TEN YEARS LATER. THIS WAS A VERY DANGEROUS AND TERRIBLE EXPERENCE FOR ME. I TRUSTED MY DOC AND I SHOULD HAVE RESEARCHED IT MYSELF FIRST! IF I WOULD HAVE KNOWN ABOUT HALF OF THE SIDEEFFECTS I WOULDN'T F 27 3 months
 11/15/2006
 1  contraception blurred vision, bloating, chills, weakness, leg pain, back pain, headaches...then After I got off of it, I bled for 3 months straight (until I got on regular BC pills and then it got back to normal), painful intercourse, dryness, ovarian cysts, and breast tissue cysts I am amazed that this drug is still on the market! I am even more amazed that doctors refuse to tell patients about the dangers of this drug. How can they sleep at night knowing they're ruining young womens' lives. I really want to have children some day and I'm terrified that I'm going to be permanently infertile. It's also taken a toll on my 5-year relationship with my boyfriend (now fiance). No matter what I do, sex is always extremely painful now, and it wasn't before I got on the shot. The makers of this drug are total crooks. I was naive when I got on this and trusted my doctor to tell me of most of the dangers and so I didn't do any research before taking it. I will never forgive myself for that. I will never trust another doctor as long as I live and I will never trust anything the incompetent FDA approves! F 22 3 months
 7/9/2006
 1  Contraception Loss of sex drive, severe depression, emotional numbness, Painful sex, lack of lubrication, lots of breakthrough bleeding, anxiety, weight gain, vaginal odor, fatigue, breast tenderness, joint pain, bloating, sore muscles, hair loss, abdominal pain, headache, nausea, acne all over my body, sweating, shortness of breath, blurred vision, chills, weakness, memory problems, and constant dark discharge I went to planned parenthood to get the Depo-Provera shot, and the clinician didn't even give me a pelvic exam! I had NEVER had one before, and she gave me the shot without examining me. Then she told me there were no side effects, just that it may cause bone thinning, and it will take 1 week to take effect. Within hours of getting the shot, my emotions were severely effected in a negative way, my body felt heavy, I was tired, and very hungry. The physical side effects wore off in a few days, but the emotional problems worsened. I was very angry, depressed, suicidal, anxious, and constantly on edge. After about a month and a half on the shot, I got a 3 week long period, and had deep brown discharge everyday for a month and a half after that. I didn't want sex at all, and even when I did sex was VERY painful throughout the three months on the shot. I am now feeling the 'detox' from being on the shot, and my anxiety is the worst its ever been!!! F 18 3 months
 1/9/2007
 1  Heavy menst cramps & Birth control Bloating (Belly, hands, feet, thighgs) numbness in right hand and right foot, EATING EATING EATING!! Moodswings, crying, bleeding non-stop, no sex drive I have found this website cause I was trying to find answers on my side effects. Okay, If Depo causes all of these, what is a girl to do? I thought it was great for the 1st 2 months and then I bloated like a balloon and gained 15 lbs in 2 weeks and I am bleeding for 6 weeks non stop. What can we use instead of Depo that doesn't have these side effects? -Dont they all make you gain weight? I am so unhappy, boyfriend's unhappy with me and I am not gonna have my next shot (unless someone can convince me its gonna get better) Can someone pls email me??? I have to get my 2nd shot in 8 days. F 26 3 months
 4/8/2007
 1  to prevent getting pregnant. I only received 1 depo shot and it was in Jan. of '05' it's now July '05' and I am still bleeding. During the first 3 months I had mood swings like crazy! I never wanted the shot again. I'd advice everyone to stick to some other method. F 17 3 months
 7/6/2005
 1  birth contol Bleeding, No weight gain, Very Moody 1 1/2 weeks after first shot started bleeding and have been bleeding now for over 2 months. I have gone to the doctor several times and they are trying different medications to try to get the bleeding under control. After shot I became very moody. Did not gain any weight. I will absolutely not be getting another shot. F 40 3 months
 11/15/2006
 1  birth control suicidality, dissociation, horrible, horrible, horrible. lay in bed for two straight weeks crying. just awful stuff. Depo is a nightmare, or at least it was for me. I got on it because of the appeal of ease of use and infrequent periods. I got one shot and it took me six months before I felt like I was back to normal, or because I got a period again. I did suffer from depression before taking it, and took the antidepressant Lexapro, which controlled my depressive symptoms quite well. Even though I continued to take Lexapro while on Depo, the depression came back worse than ever. One day I walked into the bathroom and swallowed every pill in the medicine cabinet and woke up three days later in the ICU. I am CERTAIN this never would have happened without the Depo. I felt like it took away my brain. I really cannot begin to explain what a nightmare this medication was for me. If you have ANY history of depression, DO NOT take it. F 35 3 months
 11/11/2006
 5  Weight gain, Birth control a lil bit of weight gain, moodiness I have only got up to my second shot on Depo. I could not be more pleased. I have finally gain some weight. I do get a bit moody but my friends are good they understand. I am already Bi-Polar but the shot has not in any way made me feel more depressed. I have not got a real period since, but you wont hear me complain about that either F 25 4 months
 2/5/2007
 5  Painfull periods passed flesh chunk 36 side effects total and I am not happy about it. After reading what's here I realize why I've been going down hill health wise where as I was nicely healthy before starting the shots. SIDE EFFECTS I'M EXPERIANCING: Return of psuedo seizures (that I had finally been able to stop), nausia, return of vomiting (that I had finally stopped after puking my life away for 4 years thanks to Chron's), 10 to 15 lb weight gain (noticeable within a week or so after first shot), Toe nail fungus, Slightly jaundice, obsessive, increased appatite, water retention, !!!POOR!!! digestion, IBS flare ups/ bloody mucus stooles, highly unstable emotions, serious fatigue, slight depression, poor comprehension through hearing, intense cravings, mild head aches, possible back pain from shot, very dry vaginal canal, little to no lubrication when aroused, increased breast size, breast tenderness, oily face, night sweats/ excessive sweating, cold chills, increased B.O., discharge, odd vaginal oder, iritated Chron's, bloating, VERY gassy, irritated more often, pain during sex, spotting for more than 7 days, pelvic cramps and pain and dry skin patches. I AM !!NOT!! GETTING MY NEXT SHOT AS IT'S NO F 22 4 months
 2/11/2007
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 5  endometriosis I am a little moody and have had a little vaginal dryness, The 1st couple of days after the shot, I have mild headaches, but they go away. It has been a blessing so far. No periods since I started, so no cramps! It affects everyone differently. I feel bad for the women who have had such a terrible time on it. For me it is wonderful. My doc told me when I started that it is an appetite stimulant so I needed to be careful and monitor what I ate. I did this and found that I was able to control cravings and I have lost 8 pounds, so weight gain is not a definite side effect. Don't be scared off! After reading some of the negative experiences, I almost was. Individual people have individual side effects. F 36 4 months
1X AN		 12/19/2010
 5  Birth Control I've actually had very little side effects so far. I've had mild spotting here and there and I've noticed slight hair loss, but it's okay because I have really thick hair so I can spare some of it =] I've been on Depo for about 4 months now. I was skeptical when I first started the shots after reading all these horrible reviews on it, but I went for it anyways. So far I've only had minor break through bleeding, and I've noticed some hair loss but it's not enough to make me worry. I love this birth control because I have not gained ANY weight so far. Although I do have an increased appetite. But that's something you have to learn to live with. (As my mom always say, you have to learn to embrace hunger sometimes) I was on about 7 other kinds of birth control pills before my doctor prescribed me the shot, and I'm completely happy with this one. The other pills made me moody to the point where I was constantly snapping at my family and boyfriend, but I've experienced none of that while on Depo. I really recommend that if you're thinking about going on the shot, try it. Everyone's body is different, just remember. All in all I hope that I am this happy with Depo for years to come. F 17 4 months
 7/22/2009
 5  birth control slight spotting fatigue for a week after injection Depo isnt evil like the reviews make it seem. It costs me $17 (generic brand) every 3 months which cant be beat, and you dont have to remember to take pills everyday. It did NOT decrease my sex drive, did NOT make my acne worse, did NOT make me moodier, and DID NOT MAKE ME GAIN A SINGLE POUND. I think it affects different people differently but so far so good for me. (FYI Ive been on other birth controls and had VERY negative side effects) I think it's time someone write a success story for it. Also, if youre considering depo, realize that the people who typically write these reviews only write them because they are angry. Its less likely that someone who is happy with the drug take the time to write a review. Everyones body reacts differently to different prescriptions, but because Ive had so much success with depo, I would 100% recommend it. F 22 4 months
 8/11/2009
 4  birth control light spotting at first shot, extreme mood swings, increased appetite, initial 5-10lb. weight gain, all side effects disappeared throughout the next couple months except for increased vaginal secretions second shot has brought back the intense mood swings, with a little nausea, and increased appetite. so far no more weight gain. I'm hoping the side effects will lessen over the next two months as they did before, but I am having even more vaginal secretions during arousal, which the boy is not complaining about at all. [he thinks its a compliment to him haha] I was a little iffy about depo immediately after the first shot. I have a history of bipolar, and my manic and depression symptoms increased greatly. My first period lasted about 2 weeks of light spotting, then went away. I was told by my mother who is a nurse that this would lessen and she was right. By the end of my third month, I realized that as with any drug or birth control, you will have initial symptoms until your body gets used to it. With pills, i had morning sickness much worse than I experienced with Depo. I love it for its convenience. I initially had vaginal dryness, but after a while it was like a faucet down there [sorry to be graphic] which can get annoying at times, but the man i'm seeing thinks its great...he also doesnt know its because of depo though haha. Overall, minus the mood swings, i love it. It's great to have natural spontaneous sex without the risk of getting pregnant or the stress of remembering to take my pill and forgetting and freaking out for a week. I don't reccomend it for everyone, but please don't be put off by your initial symptoms, as they will get better. Hope i helped! F 20 4 months
 4/8/2009
 4  Prevent Pregnancy Just spotting the first 4 months so far. A little lack of sex drive too (but also because I have no bf and my last bf had sexual issues himself so we rarely had sex even when I tried to initate every time)! I've tried the patch, nuvaring, and depo and so far I like the depo shot. The patch was way too strong for my small body and the nuvaring kept sliding down so much it was uncomfortable. The depo, I don't have to worry about swallowing a pill every day, put a patch on every week or the ring every month. I am going to wait for the full 9 months before deciding what to do about it. I do take calcium supplements every day and try drinking milk as much as possible too since I have a small body frame. I will try to remember to go back on the site at the end of 9 months to let y'all know if my opinion has changed or not. F 26 4 months
 6/11/2009
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 4  Birth Control Acne on my back, slight weight gain I've only had my second shot so far, but I adore it. I hated taking a pill every day (I could taste the ortho-tricyclin, and it wasn't good.) I don't have to worry about remembering anything more then an appointment, and it helps that I enjoy getting shots. My only issues are that I have gained 5 lbs - though I've been inactive - and that I've started getting acne on my back (which is so not pretty... especially since I've been wanting to get a tattoo between my shoulder blades.) F 20 4 months
 2/2/2009
 4  Birth Control, Cramps Loss of sex drive, lower back pain, spotting, depression, occasional cramps Well, I haven't gotten pregnant on it so thats a plus, but the loss of sex drive is putting a strain on my relationship, but over all I love not having a period & the spotting is about the same time I would get my period (lasts about a week) but I am depressed & worry a lot more than I used to. Overall, I would recommend it. F 19 4 months
 5/30/2007
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 4  not to get pregnant, no periods light headed, occass. nausea, minor headaches, increase in sex drive(not a bad thing), dark spotting, light bleeding I started taking depo because I couldn't remember to take the pill. I am starting on my second shot and hoping it gets better as my body gets used to it. I haven't had weight gain or increase in appetite. The first 3 months was ok with small side effects.. I had dark spotting, then light bleeding for about 3 weeks, that sucked but it just stopped over night and I haven't had it since. I am having minor headaches and a little nausea but it has helped my acne and I don't have the worry of getting pregnant. I was told these symtoms were normal with the first shot, so we will see how it effects me with the second shot. Hopefully all will go well. Good luck to anyone trying depo!! F 28 4 months
 5/11/2005
 4  birth control weight gain, moodiness, no periods I love this shot. Estrogen based BC causes problems for me, this does not. There is a small amout of weight gain but that could be other factors also. Compared to others I have virtually no side effects. this is my second time on the shot, I did stop for several years to take a break from it as my Doc warned me that it was not ment to be a long term solution. I am noticing a difference this time in that I am getting the generic version of the shot so there may be something in that particular formula that is causing a few side effects. I was warned about possible effects by my doc before deciding to start back up on it. For me this is the best BC alternative. F 43 4 months
150 1X O		 10/9/2010
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 3  pregnancy prevention Mood swings, depression, anxiety, fears over everything, acne, swelling of the hands and feet and mild fatigue. Negative effects: I'm a completely different person on this medicine. I'm usually very capable of controlling my emtions, but with this shot I'm a mess. I cry all the time over nothing whether its positive or negative. I'm also a very logical person but seem to have developed uncontrollable fears accompanied by anxiety attacks. I've also never really had acne, even as a teen, but seem to have developed it afer taking the shot. Nothing horrible, but I do have acne all over now. I also have swelling in my hands and feet at least a few times a month. Nothing terribly painful, but it does hurt mildly and becomes bothersome. Positive Effects: To speak to the positive, I'm not pregnant, so it did what it says it does. I also had no weight gain, or headaches. Would I reccomend it? Probably not. Its really nice to just have one shot and forget about it, but the effects aren't worth it. Especially with the bone density risks. Had I known of this before taking it, I wouldn't have. F 26 4 months
4X O		 6/28/2011
 3  Pregnancy prevention Nasaeu , weight gain in belly and breasts, frequent peeing, super increased apetite, head aches, nervousness, no periods, loss of "romantic" feelings...... I mean i have only had these simptoms for about a week now but Depo sucks when It comes down to knowing the scary neg. or pos. answer of being pregnant, not having a period is very scary but it's something that affects everyone 100% different F 16 4 months
2		 1/17/2012

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