DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 1  Birth Control Truly, I thought depo was great--no periods and no side effects--I THOUGHT. It turns out I now have osteoperosis. I have also gained a lot of weight (about 70 pounds) that I didn't realize was due to Depo use. Now that I have gone off Depo (about three months now), I am slowly making progress to finally lose the weight. I am way freaked out about the osteoperosis. I am way too young for that! It may look good on the surface, but I'm kinda thinking it's evil. I should have figured that out. It's not natural for a woman to not have her period. I feel like I've danced with the devil... Please be forewarned. F 41 10 years
 6/20/2006
 1  Birth Control Extreme mood swings, depression, migraines, osteoporosis, cystic acne, hair loss, dryness I have not received an injection in 9 months. I have osteoporosis evidenced by a Z-score of -2.7 which remains constant after 2 dexa-scans. ***FYI*** Fosamax and other biophosphonates are not FDA approved for use in treatment of osteoporosis in pre-menopausal women. Not many HCP's are aware of this. My migranes have improved somewhat and may now be controlled with Excedrin Migrane rather than Zomig, which gave me palpitations. My mood swings began to decrease after 6 months. Looking back, my behavior while on depo was truly manic-depressive. My therapist referred to these times as "episodes", which included uncontrollable, unpredictable fits of anger and rage followed by extreme guilt, depression, and crying. Hairloss as subsided. My bathroom floor was always covered with my hair. The cystic acne covering my cheeks and forehead resolved 6 months after my last injection. Vaginal and skin dryness continues to be a problem. I do not recommend this medication to anyone F 36 10 years
 1/2/2007
 1  birth control Gained tons of weight,hair loss,heavy periods with clotting and very severe long lasting painful acne I wouldn't recommend using this to anyone,the side effects are just horrible F 37 10 years
1X AN		 7/29/2011
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 1  Birth Control Absolutely No Periods, Fatigue, Hungry, some weight gain (mainly in mid- section), trouble sleeping, irritability, no energy at times, little to no sex drive. I have been on the Depo-Shot since I was 17 and in the 11th grade. Throughout my college years I, got the shot. Then I started to wonder why there was little to no more recent updated information on this drug. So I started to take a break from it because my doctor could not give me much more information on how safe it was to continue to stay on it as long as I have. In between my breaks, I would have terrible, excruciating, painful periods. They were so painful that I would have to stay in bed and cry because I was unable to move. Because of this pain, I would always return back to the shot to avoid this. In 2006, upon me graduating college, I stop the shot. I did not want to not have a back up birth control so my doctor put me on some BC pills. I started the pills as prescribed. I got so sick from the pills: sore breast where I could not put my arms down, could not sleep, I developed a rashy acne in the form of a beard on my face. From this, I had to start using Proactive and I have never had any skin problems in my life. I stopped the pills. I waited almost 6 months before I started the shot again. After the unbearable periods, I just could not bear it anymore. I started the shot again. Since this, I have been on the shot continuously. I finally decided again in May 2010, not to get the shot ever again because no one can give any answers on the prolonged safeness of this drug. After stopping the shot this past May I have not seen a period. No spotting or anything either. I F 28 10 years
1X AN		 9/14/2010
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 1  To prevent Pregnancy Thinning and loss of hair (bangs area), severely dry scalp, acne, numbness in hands and feet, irritable leg syndrome (that's what I thought), restlessness, joint ache, and numbness in face (was numb once for three days, doctor's were baffled. Even went to a neurologist). Started the shot after having my first child. Was on it for four years. No side effects. Stopped taking it, it took me 8 months to get pregnant. Had my baby began taking it again because I had not had any side effects the first time. It has been six years now. The side effects started with the Irritable Leg Syndrome and numbness. The hair loss just started a year ago. And the acne has started just about three months ago. What's next? F 27 10 years
? 1X O		 8/1/2010
 1  Birth Control Anxiety (paranoid), depression, mood swings I started taking the depot shot when I was a teenager. I have been off and on the drug since. Though it is worth mentioning that I have only been off it a total of 2 years in the entire ten years I used it. The first time I went off it it took about 4 months for my period to come back. It was only slightly more uncomfortable than I remember. However, I am now in my late 20s and I know that I need to take better care of my body if I want to have babies some day, so I have been off the shot since August 2009. Mind you, this is when I would have been due for my next shot. It is now going into May 2010 and I still have not had a period. I fear that I may have done damage to my fertility! This drug should be marketed as a short term solution not a long term method of birth control. No one should be on this for more than six months. I am relieved to know that I am not alone. As women we should speak out against these horrible drugs. I thought I was the only one with anxiety and depression from birth control. It's the big elephant in the room! Remember when post partum depression wasn't a common conversation topic? Now it's common knowledge! Let's bring these issues to the forefront of our health care! If we don't we will continue to suffer in silence. F 26 10 years
1X AN		 4/26/2010
 1  To not get pregnant and no period This is probably one of the worst things I've ever done to my poor body! Only good that came from it was no pregnancy and no period. This is the devils shot!! I have never been so angry and mood swings like you wouldn't believe constantly agitated weight gain! And now that I've stopped taking it I'm starting to act more normal I'm not so agitated and angry all the time but now my hair started to fall out!!! Also didn't know that the shot was 100% synthetic! Nobody ever ever told me of the horrible side effects of this drug not once until I decided to find out why was so angry by process of elimination. Thoughts my actions and everything have slowed I'm not as nervous and tense and angry and frustrated I was completely abnormal and mood swings from hell I would never do this again! If any guy wants to have sex with me in the future he's getting a vasectomy. We go through so much hell as it is a guy can certainly do it! Septa means are pretty painless and are reversible in case he wants kids later but it's about time men have to turn around and have to bend over backwards instead of us all the time! And in all honesty if there's any real honest girls out there the majority of us don't get vaginal orgasms anyway!! :) vasectomies all the way!! F 36 10 years
3 mo shot		 10/18/2014
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 1  birth control All the above name it I had it and I'm still going through it!!! It's poison! F 37 10 years
 12/26/2015
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 1  birth control i THOUGHT that the only side effect was no period, which was awesome and why i stayed on it so long. now i look at what everyone has said and i realize that there are too many coincidences. the effects that i have in common with others are: unstable mood swings, feelings of depression, lack of sex drive, dryness, painful sex, horrible night swears. ALSO now have been diagnosed w/ OSTEOPENIA I feel sick to my stomach when I look at what everyone is saying and actually thinking that I could get away with not having a period for almost 10 years and not having other side effects. I have been diagnosed with osteopenia (low bone mass density, now at risk for osteoporosis) and ONLY found out b/c my Best friend was diagnosed and told me to get a test-not even my DOCTOR told me anything. i have been in denial and now i know that i not only HAVE to get off it to try to reverse the osteopenia, but hopefully I won't feel unhappy, unstable, and will get my sex drive back. PLEASE be careful of the side effects and don't get caught up in the thrill of no periods like i did. only take short term and/or if you are going to be sure to take the calcium supplements to make up for the calcium the depo leeches from you. this didn't work for me b/c the whole reason i took the shot was b/c i couldn't remember to take a little pill. . . F 27 10 years
 9/2/2008
 1  to not get pregnant anxiety, IBS, headaches, fatigue, nauseous, vomiting, lightheaded, dizzy, abdominal pain & joint pain I loved the depo shot until I stopped taking it. I stopped taking it in june 07 and I have had all the side effects every day since. I would never go back on it after going thru what I have gone thru the past year. the doctors have done every test and say there is nothing wrong but I never had issues like I have now when I was on the shot. horrible.... F 29 10 years
 7/16/2008
 1  Birth Control 60lbs of weight gain, loss of period completely, achy everything, sex drive was gone, after getting off the shot I boinked like a rabbit. I'm also concerned that I'm sterile now. I love that 10 years later I get the news that 2 years on the shot is more than enough to make people cringe. F 26 10 years
 11/17/2009
 5  Birth Control/ No Period Vaginal Dryness I have had 2 Bone Scans both came back fine.I am very happy and will continue for as long as I can. F 25 11 years
 6/20/2009
 5  contraception weight gain, bloated feeling, food cravings Since taking this shot 11 years ago, I have had a very worry free life. Life with my heavy sickly periods was over once I started depo. I am active and like to travel, so not having to worry about periods is grand. What is helpful with my relationship is that depo controls mood swings. You are able to stay more even - not get too mad, sad, or happy. It levels you. My husband likes the way that depo helps me to be easier to live with. I would recommend it. My husband and I have no plans to have children, so it works for me. I Don't think I'll come off it any time soon. I have taken calcium and other vitamins for many years to combat the side affect of bone loss. I have a friend who is the wife of a doctor and she is trying to scare me with what she tells me about the drug causing cancer. I don't know what to believe. F 35 11 years
 2/17/2005
 5  Birth control Very few, the benefits outweight the negatives for me. It sounds like for many of you, your doctors did a poor job of educating you. ANY drug you put in your body will effect you, and effect each individual differently. I have been on depo for 11 years, and have had almost no side effects. ALL of my doctors warned me about fertility issues and bone loss, and the other effects listed here you can find listed for every other contraceptive pill on this site. I've had 2 bone scans with no loss of bone density, never had mood problems, only occasionally vaginal dryness and light spotting. Any weight loss or gain related to my diet/exercise program. I switched to seasonale 6 months ago to take a break, and due to the possibility of wanting children soon - and I hate it. I got my period back right away, that's fine, but now can't lose weight despite VERY strict diet & workout schedule, have mood swings, am exhausted and depressed. I want to switch back to depo, but will have to find another alternative. Depo can work great, but educat F 37 11 years
 1/28/2008
 5  Birth Control Loved it!!! Only one side effect- My teeth became very soft. I could be the poster child for this shot!! Loved it!!! Only one suggestion is to make sure you take calcium w/ viatim D supplements. F 35 11 years
 1/19/2009
 5  no period/no baby! 46 years old....I have been taking depo for a little over 11 years and have enjoyed not having a period. Over the past 11 years I've gained about 5 pounds, which I have no problem with. Sex is great not worrying about getting pregnant...vacations are even better not trying to schedule around a period!!! F 46 11 years
 1/8/2009
 5  to gain weight but it didn't help None. It is the best thing ever made. No periods in 11 years, not even spotting. No pregnacies. Will never get off because I don't want anymore children. I have a 12 year old and that's all I need. F 30 11 years
1X O		 1/27/2011
 5  Birth Control No period I started Depo back in highschool because I had really bad periods and the doc suggested this would help. I have had never had an of the bad side effects described by many. I did not have my periods throughout the 11 years, unless I took a break from the shot. I took a one year break about 3 years ago, just to see if my body would "act" normal, and it did. I had normal periods and was just fine. I just recently got engaged and now want start trying to have a baby after the wedding this year. So I decided to get off of the shot and get on regualar bc pills. I am experiencing sore breasts, but thats it. The first 28 days I had a period for 3 days normal bleeding and im on my second month now. So I would recommend this to people who dont experience the side effects. I have been lucky I guess, because ive never gained weight, never had mood swings, never had acne and never had a lowered sex drive. I loved it while I was on it, and although I might never go back on it after I finish having kids, I would still recommend it to anyone who wants an effective bc that is easy to use. F 29 11 years
1X day		 1/17/2011
 5  contraception Taking on and off for the past 11 years. ZERO side effects other than no period, and extended time for it to show back up after discontinuing use (not complaining). I know it's uncommon to not really have any negative side effects at all from Depo, but you're all a bunch of idiots for saying the pill is so much better just because the shot didn't work. Everyone is different. Talk to your doctor, ask questions. If your doctor is rude or you don't feel comfortable, get another doctor. FYI: the pill (3 different formulations) caused nearly every side effect of Depo listed on here for me. Also, make sure to ask about getting a bone density scan and make sure to take your calcium. F 29 11 years
every 3 mo 1X O		 1/23/2012
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 3  Contraception Periods stopped completely. I have been on the depo injection for the last 11 years as it was convenient for me and the pill made me ill. I didn't mind the fact that I had no periods as a result. I did have a break from the depo after afew years of having it, and after a year i still didnt see a period. I started a new relationship and have been back on it ever since with no side effects. I am now considering starting a family and am worried about the amount of time it will take for my menstrual cycle to return and to conceive. F 29 11 years
1X day		 2/25/2012

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