DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 3  Contraception Joint pain, mood swings, weight gain, low sex drive, leg cramps F 18 9 months
1X day		 2/21/2012
 3  Birth Control acne, mood swings, long periods months apart The first month was great. I had one period that lasted a little longer than normal but it wasn't a problem. About halfway through the second month I started getting bad acne on the sides of my chin, something I've never had before. I also have noticed recently that I am easily annoyed. I often find myself upset about little things. Also, I get very angry and jealous for no reason. I have had one additional period that lasted about two weeks but with no cramping. I have two more months on the current shot and I hope the side effects do not get worse as they are putting a strain on my relationship. I will not be getting another shot. However, I would recommend this shot for one three month interval. F 22 9 months
1X M		 12/16/2011
 3  Birth control Decreased appetite, mood swings, Bloatedness F 19 9 months
 11/10/2009
 3  contraception bloating, weight gain, acne, mood swings F 22 9 months
 5/14/2003
 3  Birth Control Lower sex drive, depression I LOVE Depo and am sad I'm about to go off it. I am taking the lower dose version where instead of injecting the shot into my muscle, it is just injected under my skin. I never have my period, I never have to think about birth control with my boyfriend and have only noticed mild depression and mild weight gain (but I have had similar side effects with other bc). What is making me go off it is a complete drop in my sex drive. I used to have a high drive and now I have ZERO! In this way, it is the best bc I've ever been on! F 26 9 months
 4/20/2007
 3  convenience irregular and prolongated periods, no period, massive mood swings, total loss of sex drive. I totally disagree with the person who says you can't blame emotional problems on this drug. Besides hearing from another doctor that she no longer recommends this drug after THREE seperate patients became suicidal while using it, I also experienced unexplained mood swings(basically complete loss of control which I've never struggled with before) depression, i never dreamed it could be my birth control! I assumed the loss of sex drive would end once my body got used to the drug but NO! I think this drug is DANGEROUS. YES, it produces the desired effect but that ddoesn't mean it's good for you. There is just so much they don't know about it, i'm glad i have become an educated consumer of this product. As far as I'm concerned the Pro's just don't outweigh the Con's. It may be working fine for some people but it's not worth the risk for me. F 21 9 months
 11/24/2007
 2  Birth control Massive weight gain, painful joints, water retention, constipation, mood swings, crying hysterically for absolutely nothing,vaginal dryness, loss of sex drive, no period until now... blood clots! been about 9 months now. i have put on almost 20 pounds all in the stomach ad butt and thighs. my boobs have shrunk seriously. Im always crying over the tiniest little thing. Very moody mostly at night. I get depressed because of my weight. I can't even bend my knees without pain (im only 21!) I have a pretty hard time using the bathroom (never did until this pill. I did like the no period thing but im 3 weeks away from my next shot and i have horrible cramps heavy bleeding and blood clots which freak me out! And major loss of sex drive. I am going to stop use and get put on a pill. Shot is not for me. Though that doesnt mean its not for everyone because all my friends love it! You just have to try it yourself. F 21 9 months
 1/8/2008
 2  birth control acne, joint pain, 20 lb weight gain in 9 months, constant need to pee, no period I've had 3 shots and have decided to not get the 4th. I immediately showed signs of weight gain (which was difficult because I've always been thin). By the 3rd month, I had facial, neck, and back acne so bad that I would lose count how many were showing at one time on my face (before the shot, I would average around 5 pimples a year! -- now I have around 20-25 pimples on my face alone every day!). By the end of the first month, I would have to pee so often that I have yet to go a night without having to wake up and go to the bathroom (never had to pee in the middle of the night before the shot). But what finally made me get off the shot?? The joint pain. The worst is in my leg-hip joints, full back and shoulders. The pain would be so bad early in the morning while still in bed, that I would have to get up out of bed (even if at 5AM) to ease the pain. The pain would be so bad, that it hurt to walk, and I would walk like an 80 yr old throughout my workplace -- it was soooo embarrassing! F 33 9 months
 5/6/2005
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 2  birth control Weight gain, no sex drive, and no feeling during sex. I need some help and this is the most useful forum I've seen. I put on some weight when I started it, but not too much. What's disturbing me more is that after my last shot I really started to feel different; before this last shot I had a lowered sex drive, but now I have really no sex drive and I have vitually no sensitivity or feeling during sex. I talked to my doctor and she said the side effects from it vary, but couldn't give me diffinitive answers. I'm happy that it's so effective in preventing conception, but I'm worried that all my sensitivity has disappeared. Is this normal and will it come back? F 26 9 months
 11/9/2009
 2  Birth control Weight loss and minor issues I will cover in comments. Very negative change in vaginal discharge and bleeding: thicker, drier, and everything started to turn brown or black! I came off of Depo in January ('09). It never did what it was supposed to because after taking it I spotted (sometimes bled) almost every day and any discharge was brown or black and tacky. After about 2 months off Depo I noticed a definite change. Improved consistency and wetness of discharge, and my sex drive improved. I have never been regular and though my periods have always been super heavy, I never experienced anything else. But since starting (and stopping) Depo, I have experienced small headaches on a regular basis, cramping (sometimes severe) and I bloat and/or experience gas pain almost daily. F 20 9 months
 10/29/2009
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 2  avoiding pregnancy Take shot every 3 months each time i get the shot a month l later down to the day i bleed for 20 days other than that no complications F 21 9 months
?		 10/1/2014
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 2  Birth Control Exceptional mood swings the week of shot. Just realizing it is drug-related. I'm normally very even tempered and thought I was just living through stressful times (coincidentally week of shot). Now I that I realize it is drug related I will stop taking it. Was exceptionally emotional and stressed at work recently (2 days after shot), made an emotional idiot of myself and now I am probably being fired. I have never come close to this in a work situation (more well versed in the art of promotion). This is horrible. Losing my job before Christmas, not knowing if how I feel/what I say is really me or just a drug side-effect is not worth the benefit of not having a period, not being pregnant, no cramps etc. F 27 9 months
x 1X O		 12/5/2011
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 2  birth control, reduce symptoms Rare light spotting, no cramping, weight gain, decreased ability to be aroused/stay aroused, harsh effects after going off shot Started using it for birth control and to reduce or eliminate my horrible cramping. I was attracted to the concept of 1 shot every 3 months. After the 1st shot, my periods started getting lighter and eventually stopped. I had no cramping which was a wonderful plus; however, after my 2nd shot, I noticed a decrease in my sex drive. I had to start using lubrication, but even with that, halfway through intercourse I would be dry again. I eventually ended up completely losing any desire to have sex. I gained 8-10 pounds mainly due to the occasional heightened appetite. I waited a month before I received my 3rd shot to give myself a little break. After the shot, I was on my period for 2 weeks and spotted off and on during the entire 3 months. My sex drive was non-existent and my poor boyfriend had to suffer. I finally decided to not receive a 4th shot which was supposed to be in late August 2010. 2 months later, I thankfully had my sex drive back to "pre-depo"; but, I developed pregnancy symptoms (lightheaded, nausea, tender breasts, etc) for months. I didn't receive a period until late October and it lasted for a month, first with old blood, then new blood. First week of December I had another period (7 days) then the day after Christmas I had a period (10 days). Now I am on my period again and it's very heavy. I'm still bleeding dried blood and new blood... I would not recommend this to anyone... not even my enemies... F 21 9 months
1X AN		 1/16/2011
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 2  to prevent pregnancy Tenderness at site of injection everytime I got it. Bloating that made me look 6 months pregnant. Horrible irritability. Fatigue that wouldn't go away no matter how much I slept. Weight gain no matter how little I ate/how much I exercised. Constant "fog" from being so tired. I have had these side effects pretty much from day one of the injection, with a little let up of bloating every other day. I first got this birth control because it sounded easy, having to take it once every 3 months, and because I was too young to have another baby. I thought all the side effects I was experiencing was just because I was a new mother. But I'm putting it down to depo for my problems. there is no way I will be getting this again F 19 9 months
1X O		 1/19/2011
 2  Privacy Hair Loss Headaches Weight Gain Mood swings I wish I never have taken this medicine Its HORRIBLE! F 19 9 months
 7/29/2005
 2  Birth Control Weight Gain, 20lbs in one month. Moodiness, total lack of sex drive. Sometimes painful to have sex. I'm getting off this drug as soon as possible now that I realize this is what is causing all the problems. F 19 9 months
 7/25/2005
 2  Birth Control I gained over 15 pounds in 9 months even though I diet and exercise. I will not get another shot. I also feel depressed, have hair loss and mood swings. F 36 9 months
 4/16/2004
 2  breast feeding Body aches, headaches, serious mood settings, find myself stressed more often, note deciding to come off it I'm quite scared cause i've already had heat flashes every so often. Any ideas if to switch to another birth control? Or maybe just take some time off, I'm already of Mommy of 1 beautiful baby girl but planning to wait for the next one???? F 21 9 months
3 shots		 5/9/2012
 1  Prevent pregnancy When I was on this shot i suffered from horrible side effects such as HOT FLASHES, NIGHT SWEATS, weird cyst like rash on my butt cheek, vagina dryness, no period, CONSTIPATION, BLOATING, SWEATING IN GENERAL, CHEST PAINS, FAST HEART BEAT, NAUSEA, ANXIETY, NERVOUSNESS, NOT ABLE TO SLEEP, no sex drive, DRY SKIN, NO APPETITE CUS OF THE NAUSEA, AND THE LIST GOES ON... I have been off this shot for 2 months May 3rd 2013 was the last day to get this shot and i said not anymore... TILL this day i still get nausea, still no period, fatigue during the day, mild cramps, still no sex drive, i lose my appetite on days i am nauseated, vagina dryness, a weird discharge, oily oily skin, nausea, acid reflex, diarrhea, pimples that hurt, mood swings, and still my sleep patterns are alil rough at bed time. The only symptoms that have left was hot flashes and night sweats. LADIES, PLEASE DO NOT GET THIS SHOT!! THE SIDE EFFECTS ARE HORRIBLE! I learned a lesson. The depo shot ruined me! If you ladies need t F 31 9 months
3 shots 3X AN		 7/19/2013
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 1  birth control Bleed for 9 months straight. Now blocked fallopian tubes. Moodiness and low libido. F 30 9 months
 6/27/2012
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