DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  heavy bleeding possibly weight gain, had been gaining weight before, mood swings when I need to get my shot, none that I get complaints about when I am on it, decreased sex drive This drug may not be the answer for everyone but for me without it my life is not pleasant. Bleeding in my shoes for days each month, terrible to the floor cramping and pain. First shot, period gone, have gone off it, takes months for it to come back but when it does it is just as bad. My mood changes when I am due to have my shot, I can feel it happening, and I will admit that I depend on it to keep me more level. I can feel the PMS when my 12 weeks is up, during the 12 weeks I have no side effects. My mom has some bone density issues and my doctor has suggested that perhaps I go off, not going to happen, it is monthly miracle, and although I understand the effects are different for everyone I say sometimes to have a more normal cycle you need to not have one. F 38 8 years
7/8/2007
 5  birth control Low sex drive, dryness, itchy, mood swings, painful sex,breast tenderness,joint pain, night sweats,insomnia, bladder control,extreme anger, no period for 8 years45 pound weight gain, constipaton digestive problems,always congested. Not having s period for 8 years is awesome! I'm having a difficult time convincing myself to Change bc. I have noticed extreme anger issues, I hate everyone, I, ram surprised I am still married due to the anger and lack of sex drive, sex is painful and dry, and is without pleasure. A few days after having sex I feel like a bladder infection or yeast infection starts. My breasts have gotten quite larger from B to DD which would be great if they were not tender...frustrating! Extreme, extreme anger! Weight gain 45 pounds in 8 years. Best figure I've ever had, most people thought I was anorexic before. Dr. Has asked that I switch bc. If it helps sex drive husband will be happy. I hope the painful sex goes away, afraid of new mood swings with new bc and having s period, never missed that. Lack of bone mass was a new concern. Dr. Gave me the scan for ibonr loss I've been on drop For 8 yrs and I'm ok, but that was scary.. so new bc here I come. I would take depo again, my husband had learned stay out of my way when I tell him I will knock you out if you don't get away from asap! F 43 8 years
.? 6X O
8/10/2011
Email
 5  Endo I absolutely love depo. I have a child and don't plan on having more so it's depo until menopause. No side effects or weight gain. Got migraines the first year but they evened out and were still better than the cramps I had before. If you gain weight and can't lose it on this find something new but don't let the small chance scare you away. This is miles better than the pill,implant,or iud. I've had them all. F 30 8 years
3/25/2014
 5  Birth control Weight loss, no periods I loved being on the depo. I did not have breakthrough bleeding, and my periods stopped all together. I lost weight. I did not experience any emotional side effects. No loss of bone density (tests completed), and I took calcium and vitamin D daily while on depo. My sex drive was not affected. The only reason I have stopped it is to better plan for pregnancy in the future. Irregular periods after stopping the depo. F 27 8 years
1X O
6/30/2014
 5  Endometriosis A couple of years ago my doc did a bone scan and I was pre-ostoporosis. I did not gain a lot of weight on depo but I had a really hard time losing weight. I mean it takes everything just to lose a pound. In the last year I started to have break through bleeding with the depo. The depo worked extermely well for me for the last 8 years. My doc recently had me have a hysterectomy because the depo wasn't working anymore. I agree it was time. F 39 8 years
6/20/2009
 5  Birth Control I suffered from headaches but was unaware that they were related to the Depo until I stopped taking the injections, and noticed that the headaches almost completely stopped. I loved Depo. I had NO PERIODS (which was fine with me!) When I stopped taking the injections at age 44, my periods NEVER resumed. That was OK, too. But coincidentally I began feeling severe fatigue, depression, and joint pain/stiffness. My doctor tested me for everything imaginable, Lupus, Lyme Disease, Thyroid, (all negative) then gave up and diagnosed Chronic Fatigue Syndrome. My OBGYN ran a bone scan and diagnosed Osteopenia and said I was Menopausal! I think now that it is not menopause but possibly some thyroid condition induced by Depo, or lack thereof! I am still miserable 4 years later. Anyone else experience misery after quitting? F 48 8 years
3/14/2008
 5  Pain management difficulty in loosing weight when i do gain it. I've been on the shots for 8 years. I would not give them up for anything! I have always had extreme menstral pain, then in 1998 diagnosed with Fibromyalgia. Not only has the shots eliminated my periods (god send)I don't have to deal with the excruciating pain of a period which was adding to the pain of the Firbomyalgia. My Fibro pain has decreased significately as well. I've rollercoastered with weight all my life, so it's just a little harder. For me IT'S WORTH IT! I have my tubes tied, I'm a single mom and grandma and yes I have absolutely no sex drive which for me works. It lets me focus on my kids. I'd rather be a little overweight and single than suffer all that pain again! F 44 8 years
5/22/2007
 5  To correct PMDD symptoms Loss of period (after a couple months), and regulation of mood predominantly. Increased energy, weight loss, ability to focus and remember better. I feel the need to put a positive review. Most people talk about how bad their body reacts to this drug. As someone who suffers severe (suicidal) depression and anxiety monthly, this medince has saved my life. I was on it for 8 years, went off to get pregnant, and recently went back on after my daughter turned 3. I had absoluetly no issue getting pregnant. Only after being off this medication did I learn the full extent of my PMS symptoms and needed to return to it. This is not a drug for everybody. Hormones are not something you should mess with lightly. One shoes does not fit all. Look at all your options, and review all the information you can. There are different hormones in each drug. There are also 2 different types of this specific drug! Make educated choices, not ones based on other peoples emotions. Not everyone has horrbile expierences with Depo. I tried many different "The Pill" and they all had their own aweful effects on me. Every Single One. Everyone's body chemistry is different. That's all. F 33 8 years
30 4X O
5/19/2016
Email
 4  To stop pregnancy I was very happy with depo I was on it long term with no periods and not much thoughts as it worked so well. I asked the nurses if I was fine on it and not having periods for so long and they said it was seen as resting my body so I stayed on it. I was then made aware that I should have had a bone scan after two years 7 years later. So I informed my doctor who put me in for a scan to find out my bones have thinned from the injection. I am absolutely gutted and if someone had told me to come off it I would have. I am currently waiting for my body to reset and scared of the periods that will come if they ever come back. I dont really know what to do regarding my bones as its so upsetting and long term I dont know if they will get strong again. This injection is great short term use but please please dont take it for longer than two years. Just get off it. I wish I had stopped after two years and changed I would have stopped if they had told me. Its not worth it. F 27 8 years
1X AN
4/2/2023
Email
 4  Because couldn't take pills I experienced about 21lbs over 8year period. It's great to have and not have periods.But when you get it off it is so hard to get regular periods back. The flow is extremely heavy. I 'am 27 years old with 1 child I would like to have one more. Being that my thew shot bee in my system so long I believe it's going to take a whle for me to have another child. If you don't want a period I suggest, but you should want your body to have a natural flow. F 27 8 years
4/1/2005
 4  Birth Control Some weight gain, less sex drive and dryness during intercourse I was a person who always forgot to take birth control pills. I would skip a day or two and end up having an irregular period. Once I found out about Depot Provera I thought F 38 8 years
2/23/2005
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 4  Birth control Some pimples - not sure if they are related to the Depo but they seemed to coincide with when I started it. It is a really convenient form of birth control and I haven't had any problems with spotting, mood swings or weight gain like a lot of other people seem to have had. F 30 8 years
4/30/2009
 4   I have been on depo for the last 8 years. About 3 years ago I took a break because of the bone density but the test came back normal. Just recently I came off of depo because I was married and my husband wants to start a family. I have a 9 year old son and we are wanting one more child. I got on depo because I had the most awful cycles and I cramped so bad I had to miss days of work. I really enjoyed the no menstruals. My Dr. did say that after coming off that it could take up to a year to become pregnant, which is around the time we are plannig on conceiving. My Dr. told me the first time I got off of Depo that I needed a form of BC to regulate my cycles again, so I got on the patch. I had regular, lighter cycles without issues so I couldn't complain. I just came off 2 months ago. I haven't had my period yet bc I haven't started my new bc patch so I will see how that goes when I begin my bc on Sunday. The only issues that I have had when off is the swollen, sore, itchy breast. It really is a pain and it hurts to touch especially when taken off my bra. I think this is one of the reasons I stayed on for so long because when I missed shots it would happen. I also recently have gained about 30lbs even when killing myself in the gym it will not come off, so I am looking forward to getting back in shape. Would I take depo again after conceiving probably. I really did like it, but I know I can't stay on it forever. IUD is really not an option for me, I hear the side effects are sometimes worse than the product. F 27 8 years
12/23/2009
 4  birth control No periods but some spotting, bone mass loss I was a loyal user of Depo from age 16 to almost 25. It was very convienient and was effective for me. I didn't have mood or weight related side effects. I switched to Implanon eventually because my bone mass was suffering from prolonged use of Depo, but I have had a lot of spotting with Implanon and I'm considering switching back. F 28 8 years
1X AN
10/29/2011
 4  birth control ~ to gain weight no periods, gained about 30 lbs in the past 8 years... i got on the depo after having my daughter in jan of 98... i almost instantly began having no periods... this went on for about 8 years... i maybe spotted once or twice a year and it didnt bother me... now my last shot was in dec of 2005 and i have yet to have another period and now my breast are so sore to the touch that it hurts to wear a bra... i know that this may be normal but geezzz... anyways i think that for the time i was on the shot i have to say i was pleased but now i am just ready to be a normal woman again and be regular... F 26 8 years
6/7/2006
Email
 4  Birth Control I have been on Depo for over 8 years. I have noticed that i have gained alot of weight while on Depo Provera. Recently i have been extremly moody towards things that i should not be. Other than that i haven't had any serious side effect in the past 8 years. F 23 8 years
12/20/2004
 4  Birth Control Weight gain, loss in sex drive, low self esteem I first started taking the depo because of bad cramps when I was 17 helped 100% I had no periods after the first year. I have gained about 20 pounds (which sucks). My low self esteem is from my weight gain. I wore a size 5/6 jeans now a 11/12. i think that it has a lot to do with my husbands and my sex lives. Only if they could make a shot with no weight gain. I don't think that I will get off from the shot. I love not have periods. F 25 8 years
5/18/2004
 4  birth control Had no menstrual cycle at all. I gained weight for the first 2 injections. After that my weight wasnt affected. My hair fell out badly. Once I stopped I was still very fertile and became pregnant immediately. I liked the every 3 mos. Refill very convenient. F 31 8 years
5/21/2012
 3  Birth Control 50 LB weight gain over 8 years, severe acne that didn't even clear with treatment by a dermatoligist, constant moodiness- at times severe depression that I needed meds for. I love the fact that I have not a period in 8 years, but the weight gain (that was a huge factor in my fiancee and I breaking up) that I haven't been able to lose no matter how hard I try (1500 a day calorie diet- go to gym 5 times a week)and the severe acne that has ruined my self-confidence isn't worth it. I just stopped the shot (within the last month) and already my face is clearing up. Hopefully I'll start losing weight soon too! F 27 8 years
5/14/2004
 3  birth control I loved loved loved depo for the 8 years I was on it. BUT i went off it in hopes of starting a family and i swear I went crazy! was it the rush of hormones?? no idea, but make sure you are under a dr's care Again, I loved the depo and I had no negative side effects. But just be aware of the change in your body when you go off it! F 35 8 years
4/10/2009

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