DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 3  Heavy period, bad cramps It works as a birth control, but I never feel good. My stomach always hurts. Memory loss, sleep insomnia. WEAKNES!! F 14 4 months
 7/5/2012
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 3  Birth control I got my shot a couple days after I got off my period and didn't have one for about 1 1/2 months i've since then got my second shot and I've been bleeding for 3 months F 16 4 months
 3/18/2005
 3  Pregancy Prevention Tired, weight gain, sore boobs, lack of sex drive. I can't take the pill - it makes me crazy. :) So I figured I'd try the shot; I've had 2 so far. I seem pretty tired all the time but that's not stopping me and could also be compounded by my career and stress. I've also gained weight which is worriesome since I'm an athlete and work out all the time and thought I could prevent the weight gain. It came in the 3rd month of the 1st shot, almost over night, but I'm determined to manage that with my diet and exercise. I haven't had the mood swings or depression others speak of and that was my problem with the pill. I do notice a lack of libido (not an absolute dead libido), which sucks, obviously, but my boyfriend is aware and we just try to do different things to make me excited. My boobs do get sore but typically only right after the shot and only for about a week or so, it tends to go away after a while. So I'd say even with the fatigue, weight gain, slight lack of sex drive and soreness of boobs sometimes - the shot is still better than the pill and condoms (and I tried those patches which were nasty) and better than getting pregnant. Hopefully after your body gets used to the hormone, these symptoms will subside. I'm going to give it the full 9 months (3 shots) before I make a decision about it. F 29 4 months
 5/20/2009
 2  Don't want kids Mood swings, nausia, acne, stress, loss of sex drive At first I liked the idea of not having to worry about taking a pill everyday, but lately I've been considering to going back to it. I find myself mad all the time. The smallest things can piss me off. Alot of the time I just want to be alone. I've even lost some weight from it because I feel nauseous all the time. I have to make myself eat so I won't feel hungry all the time. My face has broken out, and I've been using proactiv for over two years now and my face has never been as bad. And at work or school I'm always stressed out. Me and my boyfriend haven't had sex in almost a month because I'm just never in the mood. And as much as I love him, I found myself not wanting to be around him or the people I care about the most. I just don't feel like myself anymore. F 20 4 months
 9/29/2007
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 2  birth control Weight gain. Once I tried to counteract it with exercise, the bleeding began. I was fine the first month after the injection, then I bled for the next two, then it threw my menstrual cycle off for the following month, during which I just continued to bleed without abatement. Finally, the doctor put me on 10 days of pill-based Depo, and two days afterward, the strange bleeding stopped and my regular period began. I haven't bled in 2 weeks, but I still have the bloating and weight gain. Occasionally, I find myself crying at the stupidest sentimentality, which is not my usual m.o. Don't take it. F 39 4 months
 3/8/2007
 2  Birth Control hair loss, joint pain, breast tenderness, moodiness The first time I took it I was on it for about a year. I didn't notice any side effects. My period stopped all together which was great and my moods seemed good most of the time. I stopped when I started getting extreme soreness in my breasts near my arm-pits. I stayed off it for about another year, during which time I felt like I was a crazy person. Extreme anxiety. I finally decided to go back on it about four months ago. I just decided tonight that I'm not going to get my next shot. I was running my hand through my hair and a chunk of hair came out. I've been noticing a lot of hair loss when combing my hair, but didn't put it together that it was the shot causing it. It's been going on for about 2-3 months now, since I started back on the shot. About two weeks ago I also started having pain in my right hip. I can't really explain the type of pain, but it's off and on and feels like it's in the joint. There are the good sides to the shot, but for me, I just don't think it is healthy and I would not recommend it. It seems there are more people having problems than not. I believe that those who are rating it a 5 are either not aware of what it's doing to them or they just haven't used it long enough to experience the effects. F 25 4 months
 2/13/2005
 2  menstruation cycle control increased appetite, decreased sex drive, mood swings, depression, cramps, frequent spotting I was taking it because my periods were out of control but I'm going to try a different kind of birth control after this shot runs out. It took until the second 3 month cycle of depo for me to really see how horribly my body and mind are responding to this drug. I didn't gain any weight because I watch what I eat pretty closely, but I do feel hungry like ALL the time. It did help with my period, but the side effects are not worth it one bit. My mood and mental state are completely out of control and it's hurting my relationship with my long term boyfriend. F 25 4 months
1X O		 2/23/2012
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 1  Stop pregnancy and period Extreme fatigue, lightheadedness, constipation, depression, pain in joints, bladder and abdominal pressure, frequent urination, bloating, Vitamin D deficiency, excessive body hair growth, body weakness, poor circulation, obsessive thoughts, extreme paranoia, increased acne, poor digestion, hot and cold flashes, mood swings, difficulty keeping visual focus, overall body aches, pain, and lethargy, thoughts of suicide, genital discharge, incontinence, insomnia, easy bruising, etc. I was highly active and very energetic, healthy, and not overweight. BECAUSE OF DEPO I HAVE SUFFERED SINCE BEING INJECTED. I have no doubts about Depo being the root cause of my symptoms. After going months and not knowing what was wrong with me, I went to a specialist. The endocrinologist ran tests, and diagnosed me with HYPOTHYROIDISM. No doctor, nurse, or lawyer will believe the Depo is the cause, but I know it is. I didn't develop any problems causing me to be confined in my house for four months. Don't let your belief be swayed because there are thousands of women who have suffered like I have. If you are having symptoms as I described, go to an Endocrinologist. You will likely get a diagnosis and get treatment before it is too late. I now have A DISEASE FOR LIFE. I will never take Depo again. All this lifelong suffering from a single shot. F 18 4 months
150 1X O		 4/19/2011
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 1  not to have a period weight gain, personality switched from being extremely laid back and nice to being a totaly different person, constant period. I would NOT recommend this drug to anyone. I've been on it twice. the first time, it was fine, i didnt have my period and i only gained 5 pounds. This time around its horrible, Ive gained 20 pounds so far in the 4 months i've been on it. I already have major depression but I've been able to manage it myself but since i've been on this, I've hit rock bottom. I'm constantly wanting to kill myself. I can go from being my usual happy self to either snapping at someone or crying over the stupidest crap. My personality has changed completely, I've gone from being laid back, caring and sweet to being a total bitch to everyone.I'm quick to snap at anyone and thats not like me. I went back on it to get off my period but no, the last 4 months, I've had a constant period, not full-on but its not right. Its not even spotting or anything just its been constant since i went back on it. I also shake alot, have trouble sleeping and when i do sleep, i have trouble getting up. I wish that this stupid drug would be taken off the market so that nobody else has to go through this crap. F 23 4 months
1X AN		 4/16/2011
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 1  contraception Backache, dizziness, feeling weak/fatigued, changes in mood, daily crying for little or no reason, mood swings, irritability, vaginal dryness. I've been on this for around 4 and a half months now, with the first injection I had mild side effects but didnt attribute them to the depo. After the 2nd one Ive not stopped crying. Other effects like dizziness and vaginal dryness also crept in, which I wasnt experiencing before, and the aches are continuing to get worse. It all makes me a nightmare to be around, particularly for my partner, which defeats the object entirely. My next injection is due in about 5 weeks, but I will not be taking this again and hope the effects wear off soon. F 22 4 months
2X AN		 3/21/2011
 1  contaceptive excessive weight gain and hunger camparable to pregnancy I have been off the shot now for four months and have not been able to lose the weight no matter how often i work out. I gained 18 pounds on the shot in a matter 4 months and still am steadily gaining weight since the side affects are known to last up to six months after coming off. I DO NOT RECOMMEND THIS SHOT TO ANYONE! I was always thin with a high metabolism but this shot has ruined my figure. please do not ever take this medication. F 24 4 months
30mg 1X O		 4/7/2010
 1  Contraception Bleeding almost constantly since about 2 weeks after my first injection, sometimes quite heavily and with bad cramps. Anxiety, depression, moodiness, tearfulness, almost felt hysterical at times - this has caused me to have to take time off work as I felt incapable of doing my job when I would burst into tears for no reason, and I've felt lower than I ever have, but haven't been able to put it down to anything going on in my life. Do not have this poison injected into you! I had my first jab in December 2009, after trying a few different forms of the pill and finding that none of them agreed with me (either tearfulness/anxiety or bleeding before I finished the pack). I had previously had Depo when I was 18 or 19, and found that it stopped my periods, but was hell when I came off it. I bled pretty much solid for six months when I stopped it the last time I tried it. This time, I knew I wanted contraception for a few years and knew my experiences of coming off it wouldn't happen again for quite some time, so I decided to try Depo again. How wrong was I?! I started bleeding a couple of weeks after my first jab four months ago and haven't stopped apart from maybe 2 weeks during that time. Emotionally I've gone through hell too, feeling like I was cracking up and unable to go to work for a couple of days because I felt so hysterical one minute and so low the next. I can't wait for this to get out of my system; I've read it will take at least 6 months. There is no way of getting it out of your system any quicker, it's not reversible if your experience of depo is as hellish as mine. Think very carefully about having this, even if a previous experience of Depo was okay, it seems it affects your body differently as you age, as well as it affecting different people in different ways. F 27 4 months
1X AN		 4/11/2010
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 1   Massive headaches, Mood swings, Painful intercourse (sometimes), Constantly tired, Spotting, Cramp like feelings, Ringing of ears. DON'T TAKE THIS SHOT!!!!!!!!!!!!! Its been a living nightmare! After the first shot i had only a few of the side effects. When i went back to Planned Parent Hood the scum bags there told me the side effects weren't related to the shot and gave it to me again. Ever since the second shot i have felt like complete sh*t! Please read up on this shot before you take it....it can really mess up your body....and your sex drive! F 25 4 months
 10/12/2007
 1  Endometriosis huge weight gain, 40 lbs in 3 months, unable to lose any weight even after 8 years off the drug this drug should be banned, it's a night mare, I only took 4 shots the doctor said "this will shut down everything" when she knew I needed a hysterectomy I'd had my children I was supposed to take it for 6 months and could only take it for 4 and 9 years later I still have all of the effects everyone else notes and despite lots of exercise and eating well I can't lose any weight, I was only 32 when I took this and am now 40 and absolutely miserable about this I wish I'd known this before it ruined me! It needs to be banned. F 40 4 months
 4/3/2007
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 1  cysts and heavy bleeding This shot is poison! A few weeks after my first shot began having dizzy spells and abdominal pain...took the second shot 3 weeks ago abd truly regret it. Been to the emergency room for heart palpitations chest pain and difficulty breathing... been to my primary doctor now who thinks sypmtoms may be related to anxiety with the Depo shot... as i sit and write this review im on a heart monitor for 7 days to rule out anything cardiac.... been severely depressed, cry atleast once a day over not feeling like myself. This shot is the worst drug available.... cant sleep, cant eat without feeling nauseous! Not to mention the extreme fear felt from the anxiety! I can't drive or even get out of bed most days! Worst part is when I called my OBGYN they said there is nothing they can give to counteract the shot .... just have to wait for it to get out of my system! TRUST ME ..... DO NOT EVER TAKE THIS SHOT! IT IS THE WORST EVER AND SHOULDNT BE ON THE MARKET! F 43 4 months
 5/21/2013
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 1  no period, pregnancy prevention ACNE, mood swings,weight gain, constant spotting, cramps, anxiety, fatigue, weakness. I switched to the shot because I was always forgetting to take my pill, so I figured the shot would be worth it. I THOUGHT WRONG. Worst decision I've ever made, my face used to be flawless when I was on the pill, now I have moderate ache breakouts id say once every week and a half. I have no patience with anyone, I fell into a depression for a couple of months, and I constantly have to check and make sure I'm not spotting. Not to mention I've gained 6 pounds per shot. I'm so done with it. And if you want kids in the future, forget about it, this thing messes up your fertility and hormones so bad, it'll be like you're on birth control forever because its going to be impossible to get pregnant. Don't take it, the cons outweigh the pros in almost ever depot case! I'm switching back to the pill ASAP and I WILL take it like I should, especially after this horrendous experience. Stay away from it at all costs. F 17 4 months
least am.		 8/21/2012
 1  Prevent Pregnancy Spotting, Depression, Mood Swings, Extreme Anger, Suicidal thoughts. Sadness, Crying and emotional. Last night I got so upset with my boyfriend...I have never felt that kind of anger ever! Stayed up all night thinking what the heck is wrong with me...then it hit me. It's this damn shot!!! I'm normally a girl who can control my emotions, let things go. But lately I've been getting extremely angry, feeling sad for no reason and I never put the math together. I just recently got my 2nd shot and the thought that this will be in my body for another 3 months worries me. DO NOT take this shot. Try every other option before going on Depo. Like someone said its better to have a baby, than to be having suicidal thoughts and depressed. F 27 4 months
1X O		 1/3/2013
 1  Birth control Weight gain, anxiety, mood swings, depression I got this shot because I can not take the pill due to blood clots and needed something until my husbands vasectomy. About a couple weeks after my first shot I was constantly irratated by EVERYTHING and yelling at my kids every day for nothing, I did not want to be around anyone either, just wanted to be by myself all the time. This was something I had never experienced. I realized some days later that it was side effects of this shot. I called my OB/GYN office and explained my experiences and have been put on Zoloft! I have to apologize to my friends, family and especialy my young kids and explain that it is not me it is this shot that is making me a raging b*tch. I am still having some bouts of anxiety, anger, mood swings and depression even on the Zoloft but am trying to recognize it and correct it (which doesnt always work). Oh, and I have also gained 5 lbs with the first shot; just got my 2nd so who knows what I will gain with that. Can not wait to be off of this. F 4 months
1X O		 12/26/2012
 1  Endometriosis I experienced weight gain, depression, hair loss, continued to bleed constantly and for three months after the shot wore off. I would never use this again, but to all of you suffering the lasting effects of bleeding and anxiety I used acupuncture and it completely cured the problems caused by Depo. There is a "stop bleed" acupuncture point which stopped my three months of bleeding within four sessions. F 36 4 months
 5/15/2007
 1  OVARIAN CYSTS NAUSEA TIRED ALL THE TIME/ WEAKNESS HEADACHES ABDOMINAL PAIN ACHNE DEPRESSION MOOD CHANGES I HATE THIS DRUG! F 22 4 months
 10/15/2007

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