DEPO-PROVERA Reviews (MEDROXYPROGESTERONE ACETATE)

Average Rating: 2.1 (2471 Ratings)

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 ESTROGENS PROGESTINS ANTINEOPLASTICS

 Type: Rx Drug

  

DEPO-PROVERA  (MEDROXYPROGESTERONE ACETATE):  This medication is used to treat certain types of cancer (such as uterine cancer, kidney cancer). Medroxyprogesterone is like a natural hormone called progesterone made by the body. It is usually used with or after other treatments (such as radiation, surgery). Medroxyprogesterone may prevent or slow the worsening of the cancer and decrease pain and other symptoms.    (Sources: U.S. Centers for Medicare Services, FDA)

  

More on DEPO-PROVERA: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DEPO-PROVERACOMMENTSSEXAGEDURATION/
DOSAGE		DATE ADDED
 
 3  Prevent Pregency I didn't have side effects while I was on the shot. I love the shot no periods was the best part. But when I stop taking the shot the periods began. I stop taking the shot around the end of November and for the whole month of December my period was on and for the months that followed. My breast was also sore. I loved it while I was on it, but after I got off of it I hated it. F 17 3 years
 1/4/2005
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 3  Birth Control weight gain (40lbs.) mood swings, leg cramps I started this after my first child and I had my period for about 2 months! Then I never went back for my follow up shot. Three years later I decided to try it again and I loved it! No periods, no pills, and it even improved sex drive. Now Im trying to get pregnant again and I am experiencing some things I cant explain. I dont know if its because im off the shot or something else. I dont have insurnce anymore so I cant talk to a doctor about it. F 25 3 years
 4/13/2008
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 3  birth control i would like to say that for about the first year i loved it. no problems what-so-ever. now, in the past year, ive experienced severe joint and muscle pain and breast tenderness, extremely emotional, extreme mood swings - i get frustrated very easily, i feel anxious, nervous, and irritability a lot of the time. it started with the low sex drive, but it went away. then came the night sweats, i have them pretty much every night. i have a lot of the symptoms mentioned by the other women, but minus the weight gain.. i have lost about 10lbs that i cannot get back. and i have not had any issues with hair.. yet. i took my last shot in oct and i NEVER plan on getting another. the psychological effects are what's really getting to me. i hate wanting to cry all the time.. and i hate fighting with my boyfriend. if this drug works for you, go for it, but once you start feeling any symptoms, stop while you still can and get help. im so scared because i have no idea how much this drug actually hurt me. F 19 3 years
 12/19/2007
 3  Period and pregnancy With the shot i never had periods , but I always felt so weak and I would gain so much weight . When I decided to stop taking it because my doctor suggested I try something else I started getting feverish flashes, cramps that make me cry , it would make me nauseous where I couldn't eat , it was helping at first but after I couldn't get up in the mornings and I gained 50 pounds I wish I would've never started. Don't mess up your body F 18 3 years
 2/18/2017
 3  Prevent pregnancy I was on the depo shot for about 3 years and decided to skip my last shot. I am now dealing with what seem to be withdrawl symptoms (headache, body aches, fatigue, shortness of breathe, loss of appetite, feeling of having a viral infection, and as of lately a little bit of nausea) has anyone had anything similar to this when coming off of this shot? F 29 3 years
4X O		 7/22/2022
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 2  Period Control, Birth Control depression, mood swings, steady weight gain, complete lack of sex drive. Every body is different, but Depo did not work for mine. When I started on the shot I weighed 128 lbs; I now weigh 158 even though my lifestyle/eating habits have largely stayed the same. The lack of libido due to the shot's hormones have negatively affected my relationship with my boyfriend. How do you tell a guy you "just don't want sex anymore" without hurting his feelings? You can't. All the side effects of the shot are just not worth the convenience of having no period and only needing one shot every 3 months. I'm switching birth control methods this Tuesday, and I'm very excited. F 21 3 years
 2/10/2008
 2  Previous pregnancy on the pills! While taking using the DEPO PROVERA shot I experienced weight gain, depression, paranoia, bloating, hair loss, missed cycles, and frequent headaches. After taking the shot was returned I returned to have displaced cycles and did not experience a normal cycle until month 17 of quitting the shot. For me the recovery portion of my entire cycle of cleaning out was worst for me. Complete sadness and wondering if my system would ever become normal, missing cycles and hoping pregnancy occurred only to be let down by negatives after negative. It took me 19 months after depo and three cycles to conceive a child which I am now currently 9 weeks pregnant with! I guess I am one of the lucky one that depo did not effect that horribly. I have read millions of horror stories about depo, doctors should not be allowed to give this horrible medication to anyone at anytime! Like many of you I was never told a complete list of the possible side effects. If I would have knew then what I knew now I would have NEVER taken the shot! F 26 3 years
1X O		 6/20/2013
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 2  Prevent pregnancy- forced by father Headaches depression and weight gain When I was 12 (almost 13) my parents forced me to go on the shot..I am still a virgin and the shot makes me hate everyone and everything..so I'm never going to have sex anyway..I've only had 1 period and the next day I was on birth control..I hope this doesn't make it impossible to have kids F 16 3 years
 12/23/2014
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 2  Contraception Headaches, thickness of the breast caused by harmonal changes, mood swings, aching knees and feet, stomach cramps, tiredness, bloating and weight gain Used depo provera for 2 years without many problems then had a break to have a baby. Been back on it now for a year and think it's time to stop taking it for good as this time round it's causing so many symptoms F 33 3 years
1X day		 9/1/2015
 2  Severe Endometriosis MOOD SWINGS!! Joint Pains, Weight Gain, Disorganized Speech, Hair Loss, Spotting, Bloating, Tiredness, Memory Loss, and Frequent Urination. I absolutely HATE this shot. However, because I have a severe case of endometriosis I have no other choice but to take it because no other pills, patch, ring etc..will work. I bleed through all of them. I am moody as hell all the time and have developed a very quick vicious temper. I've been on it 3years and have gained 15lbs (I am only 5ft tall so that is horrendous!). It's hard to control what you eat because the cravings are insane. I have managed to keep an eye on what I eat lately which seems to help, I lost a little weight. Sometimes I forget things right after someone tells me. Not sure if my brain is preoccupied or if this is from the shot. I also have disorganized speech. For example, if I'm trying to explain something my words get jumbled up or I use wrong words and it ends up making no sense. Not sure if this is really a side effect but I saw it on one of the other sites and it said it was. MY knees recently started to really bother me, its kind of like they feel swollen and they ache. I still get bad cramps sometimes but no period. I do randomly spot throughout the cycle. I absolutely hate this shot but its the only thing that will help slow down/treat my endometriosis and stop my heavy periods so I assume its serving its purpose. Otherwise I would NOT recommend taking it! Thank god for my boyfriend being so patient and understanding or I would lose my mind F 24 3 years
4X O		 9/28/2012
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 2  birth control acne, loss of sex drive, still no period (have been off 7 months) i wouldn't recommend it!!!! F 34 3 years
 10/8/2007
 1  Birth Control I experienced a deacreased sex drive and severely painful intercourse! I have been to the doctors for painful intercourse and they never mentioned that depo could be the cause. They never found out the cause either and I still suffer from severely painful intercourse! Now I know that depo is the cause! I am getting off depo-provera and hopefully I will return to normal.My boyfriend thought that I just did not find him physically appealing and my boyfriend is HOT! It's not worth ruining a loving 4 year relationship! I only reccommend it to young females that are not in serious relationships, because it can ruin your relationship with your boyfreind. F 18 3 years
 10/21/2004
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 1  Birth Control Decreased interest in sex, extremely painful intercourse. The first 1 1/2 years on depo were great. No periods - that's why I went on it in the first place. However, as time went on I noticed that sex was becoming a bit painful. It got to the point that when I went to the doctor about it she could barely examine me as it caused me so much pain. She told me it was because of the Depo. I am now waiting for the shot to wear off and hope I get back to normal has quickly as possible. I would NOT recommend that anyone take this. This side effect has been horrible. I've been doing a lot of reading since this has happened to me and realize that my hair loss, memory loss, and irritability may have something to do with the Depo as well. I think this is a nasty drug, and doctors need to be more upfront in telling patients about the side effects. F 42 3 years
 4/20/2004
 1  pregnancy prevention I had extreme bleeding for weeks when STOPPING depo, I have bled through my pad in a 1/2 hour,serious lack of libidio to the point of wanting to throw up when being touched, aggression/depression, hair loss, speech problems Please do not take this drug it isnot worth it, I used to love depo when I first started taking it, now I'm just scared about how long it will be before I can go on with my life F 26 3 years
 4/26/2004
 1  doctors panic attacks,extreme depression,moody,bitchy,im fucking fat i was a size 6-8 now im 12-14,i cant stop crying,i hate my life,im always tired people think im a fat lazy bitch,i thought i was going crazy,i hate this shit they have been injecting into me for the last 3yrs im only 21 and i feel like im60.i cant lose weight at all.my 4yr relationship is crumbling,ive lost all my friends confidence sexdrive,hair,im getting this shit banned i swear to you im suing the shit out of the manufactors. STAY AWAY FROM THIS SHIT IF YOU WANT TO LIVE HAPPILY. F 21 3 years
 3/23/2007
 1  Contraception Decreased sex drive, depression, 25 lb weight gain, increase in frequency of migraines, no periods, increase in perspiration and odor... I also was told this was safe, and that my periods would go away. I went on the shot 3 years ago when my son was six weeks old. I was warned that it may decrease my milk production but it didn't. But after 2 years it seems my sex drive was not recovering at all. My doctor merely suggests my husband get a vasectomy. Now another year later and my husband is complaining again about sex, so I do some research. And I find the other side effects...it explains so much about what's been happening to me the last 3 years! I love sex but just getting in the mood is the problem. Now I have a reason for being tired all the time, and more migraines, and not being able to lose the weight I gained after I started taking the shot (I lost most of the baby weight int he beginning), even with healthier eating and exercise. I took the pill before and got pregnant three times...I love my boys, but that's one of the reasons I have stayed on Depo...the effectiveness and you don't have to remember to F 38 3 years
 7/27/2006
 1  To prevent pregnancy Constantly hungry, eating a lot, weight gain, shortness of breath, bloating, fatigue, nausea, headaches, mood swings, major depressive disorder Depo provera gave me clinical depression that I had to start taking medication for. Depo provera also made me fatter. Do not use this drug no matter what; tell him to use condoms. F 28 3 years
the shot 1X AN		 1/28/2013
 1  Birth control This shot is awful. Irritabilty, no sex drive, headaches, joint pain, extreme and constant fatigue, muscle weekness, hot flashes...all while being ON the shot. Once off, extreme loss on bone density, really bad symptoms while ovulating each month, and not being able to get pregnant again, 2years after being off of it. Still getting constant headaches and constantly tires, nauseous and weakness. This drug is literally poison, please stay away!!! F 29 3 years
1mg		 12/7/2012
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 1  birth control many:extreme fatigue, major depression, joint pain, loss of libido, extreme vaginal dryness, total loss of period, gained weight, then lost weight and was diagnosed with Graves' disease (went to 90 lbs. at 5"5'). Went off it (after Graves' got better): irregular periods then none for 6 months, migranes, joint popping, back pains etc. I have been off it for 1 year and do not recommend it. I immediately felt better once I stopped it however still do not feel like my previous self, especially as far as energy, still extreme fatigue for 34 years old. It doesn't seem it was tested well b4 entering the market! F 3 years
 4/4/2006
 1  form of birth control well lets see i gained about 25-30 pounds and went from a size 1/2 to a size 5/6 deffinetly not happy of that fact, severe anxiety, mood swings, depression, weight gain, acne, decreased in sex drive, severe abdominal pain, muscle aches, memory problems... This injection has truly ruined my life..i went from a happy go lucky person to a being very depressed and a lot less motivated to do ne thing, not impressed with the weight gain, i have joined the YMCA hoping that i can loose the weight, i can truly say that it has ruined my relationships with my friends and with my more serious relationship with my bf, the depression has made me not want to do ne thing but feel tired and constant paranioa that bad things are going to happen to me, i feel i could have done better in school, and with my life..im proud to say that i am off the needle and back on the pill so im hoping that i will be back to normal soon! F 18 3 years
 1/17/2006

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